A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Ernst, Katharina ^a   Liebscher, Markus ^b   Mathea, Sebastian ^b   Granzhan, Anton ^c   Schmid, Johannes ^a   Popoff, Michel R ^d   Ihmels, Heiko ^c   Barth, Holger ^a   Schiene Fischer, Cordelia ^b,e  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b MAX PLANCK RESEARCH UNIT FOR ENZYMOLOGY OF PROTEIN FOLDING   (Germany)

^c UNIVERSITY OF SIEGEN   (Germany)

^d INSTITUT PASTEUR   (France)

^e MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN; HEAT SHOCK PROTEIN 70; IOTA TOXIN, CLOSTRIDIUM PERFRINGENS; MOLECULAR LIBRARY; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BINDING SITE; CELL LINE; CELL SURVIVAL; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; HEK293 CELL LINE; HELA CELL LINE; HT-29 CELL LINE; HUMAN; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; VERO CELL LINE;

ADP RIBOSE TRANSFERASES; ANIMALS; APOPTOSIS; BACTERIAL TOXINS; BINDING SITES; CELL LINE; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; HEK293 CELLS; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HT29 CELLS; HUMANS; SMALL MOLECULE LIBRARIES; VERO CELLS;

EID: 84957837635     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20301     Document Type: Article

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