Cyclophilin A facilitates translocation of the Clostridium botulinum C2 toxin across membranes of acidified endosomes into the cytosol of mammalian cells

Cellular Microbiology

Volumn 11, Issue 5, 2009, Pages 780-795

  Kaiser, Eva ^a   Pust, Sascha ^b,c   Kroll, Claudia ^a   Barth, Holger ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADENOSINE DIPHOSPHATE; BOTULINUM TOXIN; BOTULINUM TOXIN C 2; CYCLOPHILIN; CYCLOPHILIN A; CYCLOSPORIN A; EXOENZYME C2; HEAT SHOCK PROTEIN 90; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PEPTIDYLPROLYL ISOMERASE; UNCLASSIFIED DRUG;

ACIDIFICATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL LYSATE; CELL MEMBRANE; CHANNEL GATING; CLOSTRIDIUM BOTULINUM TYPE C; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; ENDOSOME; ENZYME ACTIVITY; EUKARYOTIC CELL; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; INTERNALIZATION; MAMMAL CELL; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN TRANSPORT; VERO CELL;

ADP RIBOSE TRANSFERASES; ANIMALS; BOTULINUM TOXINS; CACO-2 CELLS; CERCOPITHECUS AETHIOPS; CYCLOSPORINE; CYTOSOL; ENDOSOMES; HELA CELLS; HT29 CELLS; HUMANS; PROTEIN INTERACTION MAPPING; PROTEIN TRANSPORT; VERO CELLS;

CLOSTRIDIUM BOTULINUM; EUKARYOTA; MAMMALIA;

EID: 64049084122     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2009.01291.x     Document Type: Article

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