Conserved conformational changes in the ATPase cycle of human Hsp90

Journal of Biological Chemistry

Volumn 283, Issue 26, 2008, Pages 17757-17765

  Richter, Klaus ^a   Soroka, Joanna ^a   Skalniak, Lukasz ^a   Leskovar, Adriane ^b   Hessling, Martin ^a   Reinstein, Jochen ^b   Buchner, Johannes ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIMERIZATION; HYDROLYSIS; PROTEINS; SIGNAL TRANSDUCTION; YEAST;

ACTIVATION PROCESSES; ATP HYDROLYSES; ATPASE REACTIONS; BASIC PRINCIPLES; BINDING DOMAINS; CONFORMATIONAL CHANGES; CONFORMATIONAL REARRANGEMENTS; CRITICAL STEPS; DIMERIZATION DOMAINS; DO-MAINS; ENZYMATIC MECHANISMS; LIMITING STEPS; MECHANISTIC ASPECTS; MOLECULAR CHAPERONES; PROTOMERS; SIGNAL TRANSDUCTION PATHWAYS; SUBSTRATE PROTEINS; TERMINAL DOMAINS;

PORT TERMINALS;

ADENOSINE TRIPHOSPHATASE; GLUCOSE REGULATED PROTEIN 94; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 ALPHA; HEAT SHOCK PROTEIN 90 BETA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL PROTEIN TRAP1; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; FUNGAL PROTEIN; HSP90AB1 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; DIMERIZATION; ENZYME CONFORMATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STABILITY; REACTION ANALYSIS; YEAST; CHEMISTRY; CHROMATOGRAPHY; CYTOSOL; DOSE RESPONSE; GENE DELETION; KINETICS; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; CHROMATOGRAPHY; CYTOSOL; DIMERIZATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FUNGAL PROTEINS; GENE DELETION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; HYDROLYSIS; KINETICS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 49649113716     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800540200     Document Type: Article

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