Plasma first resuscitation reduces lactate acidosis, enhances redox homeostasis, amino acid and purine catabolism in a rat model of profound hemorrhagic shock

Shock

Volumn 46, Issue 2, 2016, Pages 173-182

  D'Alessandro, Angelo ^a   Moore, Hunter B ^a,b   Moore, Ernest E ^a,b   Wither, Matthew J ^a   Nemkov, Travis ^a   Morton, Alexander P ^a,b   Gonzalez, Eduardo ^a,b   Chapman, Michael P ^a,b   Fragoso, Miguel ^a,b   Slaughter, Anne ^a,b   Sauaia, Angela ^a   Silliman, Christopher C ^a,c   Hansen, Kirk C ^a   Banerjee, Anirban ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b DENVER HEALTH MEDICAL CENTER   (United States)

^c Bonfils Blood Center   (United States)

Author keywords

Metabolomics; normal saline; plasma first; shock

Indexed keywords

AMINO ACID; ASPARAGINE; ASPARTIC ACID; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLYCINE; HISTIDINE; LYSINE; METHIONINE; PHENYLALANINE; PURINE; SODIUM CHLORIDE; THREONINE; CRYSTALLOID; ISOTONIC SOLUTION; LACTIC ACID; PURINE DERIVATIVE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VOLUME; CATABOLISM; COMPARATIVE STUDY; CONTROLLED STUDY; ENERGY METABOLISM; FLUID RESUSCITATION; HEMORRHAGIC SHOCK; LACTIC ACIDOSIS; MASS SPECTROMETRY; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PLASMA TRANSFUSION; PROTEIN DEGRADATION; PURINE METABOLISM; RAT; THROMBOCYTE FREE PLASMA; TRANSAMINATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UREA CYCLE; ACIDOSIS; ANIMAL; FLUID THERAPY; MALE; METABOLISM; PHYSIOLOGY; PLASMA; PROCEDURES; RESUSCITATION; SPRAGUE DAWLEY RAT;

ACIDOSIS; AMINO ACIDS; ANIMALS; FLUID THERAPY; ISOTONIC SOLUTIONS; LACTIC ACID; MALE; PLASMA; PURINES; RATS; RATS, SPRAGUE-DAWLEY; RESUSCITATION; SHOCK, HEMORRHAGIC;

EID: 84957812451     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000588     Document Type: Article

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