Fresh frozen plasma resuscitation attenuates platelet dysfunction compared with normal saline in a large animal model of multisystem trauma

Journal of Trauma and Acute Care Surgery

Volumn 76, Issue 4, 2014, Pages 998-1007

  Sillesen, Martin ^a,b   Johansson, Pär I ^b,c   Rasmussen, Lars S ^b   Jin, Guang ^d   Jepsen, Cecilie H ^a,b   Imam, Ayesha ^a   Hwabejire, John O ^a   Deperalta, Danielle ^a   Duggan, Michael ^a   Demoya, Marc ^a   Velmahos, George C ^a   Alam, Hasan B ^d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health   (Denmark)

^c UNIVERSITY OF TEXAS   (United States)

^d UNIVERSITY OF MICHIGAN HOSPITALS   (United States)

Author keywords

brain; endothelium; platelets; swine; Trauma

Indexed keywords

ADENOSINE DIPHOSPHATE; CD40 LIGAND; FIBRINOGEN; FRESH FROZEN PLASMA; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOD CELL COUNT; BLOOD CLOTTING; BLOOD GAS; BLOOD VOLUME; CONFERENCE PAPER; CONTROLLED STUDY; ENDOTHELIUM INJURY; FEMALE; HEMODYNAMICS; HEMORRHAGIC SHOCK; LIVER INJURY; MEAN ARTERIAL PRESSURE; MULTIPLE TRAUMA; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION; RIB FRACTURE; SOFT TISSUE INJURY; SWINE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE DYSFUNCTION; THROMBOCYTE FUNCTION; THROMBOELASTOGRAPHY; TRAUMATIC BRAIN INJURY;

ANIMALS; BLOOD PLATELETS; DISEASE MODELS, ANIMAL; FEMALE; MULTIPLE TRAUMA; PLASMA; PLATELET ACTIVATION; RESUSCITATION; SODIUM CHLORIDE; SWINE;

EID: 84897057737     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000000193     Document Type: Conference Paper

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