Early hemorrhage triggers metabolic responses that build up during prolonged shock

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 308, Issue 12, 2015, Pages R1034-R1044

  D’Alessandro, Angelo ^a   Moore, Hunter B ^a   Moore, Ernest E ^a,b   Wither, Matthew ^a   Nemkov, Travis ^a   Gonzalez, Eduardo ^a   Slaughter, Anne ^a   Fragoso, Miguel ^a   Hansen, Kirk C ^a   Silliman, Christopher C ^c,d   Banerjee, Anirban ^a  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b DENVER HEALTH MEDICAL CENTER   (United States)

^c Children's Hospital Colorado   (United States)

^d Bonfils Blood Center   (United States)

Author keywords

Hemorrhagic shock; Mass spectrometry; Metabolomics; Plasma; Trauma

Indexed keywords

ADENOSINE; CITRULLINE; FATTY ACID; GLUTAMIC ACID; GLUTATHIONE DISULFIDE; NICOTINAMIDE; ORNITHINE; POLYAMINE; SPERMIDINE; SPERMINE; TISSUE PLASMINOGEN ACTIVATOR; URATE; BIOLOGICAL MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CITRIC ACID CYCLE; CONTROLLED STUDY; ENERGY METABOLISM; FIBRINOLYSIS; GLYCOLYSIS; HEMORRHAGIC SHOCK; HYPERGLYCEMIA; HYPERMETABOLISM; LIPID OXIDATION; LIPOLYSIS; MALE; MASS SPECTROMETRY; METABOLISM; METABOLOMICS; NITROGEN METABOLISM; NONHUMAN; PRIORITY JOURNAL; RAT; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; UREA CYCLE; ANIMAL; BLOOD; BLOOD VOLUME; DISEASE MODEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PATHOPHYSIOLOGY; PHENOTYPE; PROCEDURES; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; BIOMARKERS; BLOOD VOLUME; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; MALE; MASS SPECTROMETRY; METABOLOMICS; PHENOTYPE; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; TIME FACTORS;

EID: 84931097002     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00030.2015     Document Type: Article

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