A review of the mechanisms of blood-brain barrier permeability by tissue-type plasminogen activator treatment for cerebral ischemia

Frontiers in Cellular Neuroscience

Volumn 10, Issue JAN, 2016, Pages

  Suzuki, Yasuhiro ^a,b   Nagai, Nobuo ^c   Umemura, Kazuo ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OHU UNIVERSITY   (Japan)

^c NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

Blood brain barrier permeability; Brain ischemia; Endothelial endocytosis; Intracranial bleeding; Tissuetype plasminogen activator; Vascular endothelial growth factor

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALTEPLASE; CLAUDIN 5; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; OCCLUDIN; PLASMIN; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE; STROMELYSIN; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

BLOOD BRAIN BARRIER; BLOOD CLOT LYSIS; BLOOD VESSEL PERMEABILITY; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; ENDOCYTOSIS; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HUMAN; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RECANALIZATION; REPERFUSION INJURY; REVIEW; TIGHT JUNCTION; TRANSCYTOSIS; VASCULAR REMODELING;

EID: 84957800953     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2016.00002     Document Type: Review

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