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Volumn 285, Issue 6 54-6, 2003, Pages

Effects of hypoxia-reoxygenation on rat blood-brain barrier permeability and tight junctional protein expression

Author keywords

Hypoxemia; In vivo; Occludin

Indexed keywords

ACTIN; CLAUDIN; CLAUDIN 3; OCCLUDIN; SUCROSE; UNCLASSIFIED DRUG;

EID: 0344009459     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00589.2003     Document Type: Article
Times cited : (164)

References (72)
  • 2
    • 0032925674 scopus 로고    scopus 로고
    • Combination of hypoxia/aglycemia compromises in vitro blood-brain barrier integrity
    • Abbruscato TJ and Davis TP. Combination of hypoxia/aglycemia compromises in vitro blood-brain barrier integrity. J Pharmacol Exp Ther 289: 668-675, 1999.
    • (1999) J Pharmacol Exp Ther , vol.289 , pp. 668-675
    • Abbruscato, T.J.1    Davis, T.P.2
  • 3
    • 0016380398 scopus 로고
    • Mechanisms activating glycolysis in the brain in arterial hypoxia
    • Bachelard HS, Lewis LD, Ponten U, and Siesjo BK. Mechanisms activating glycolysis in the brain in arterial hypoxia. J Neurochem 22: 395-401, 1974.
    • (1974) J Neurochem , vol.22 , pp. 395-401
    • Bachelard, H.S.1    Lewis, L.D.2    Ponten, U.3    Siesjo, B.K.4
  • 4
    • 0034038626 scopus 로고    scopus 로고
    • Multiple domains of occludin are involved in the regulation of paracellular permeability
    • Balda MS, Flores-Maldonado C, Cereijido M, and Matter K. Multiple domains of occludin are involved in the regulation of paracellular permeability. J Cell Biochem 78: 85-96, 2000.
    • (2000) J Cell Biochem , vol.78 , pp. 85-96
    • Balda, M.S.1    Flores-Maldonado, C.2    Cereijido, M.3    Matter, K.4
  • 5
    • 0023186372 scopus 로고
    • Cerebral circulation, metabolism, and blood-brain barrier of rats in hypocapnic hypoxia
    • Beck T and Krieglstein J. Cerebral circulation, metabolism, and blood-brain barrier of rats in hypocapnic hypoxia. Am J Physiol Heart Circ Physiol 252: H504-H512, 1987.
    • (1987) Am J Physiol Heart Circ Physiol , vol.252
    • Beck, T.1    Krieglstein, J.2
  • 6
    • 0025048342 scopus 로고
    • Electrical resistance across the blood-brain barrier in anaesthetized rats: A developmental study
    • Butt AM, Jones HC, and Abbott NJ. Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study. J Physiol 429: 47-62, 1990.
    • (1990) J Physiol , vol.429 , pp. 47-62
    • Butt, A.M.1    Jones, H.C.2    Abbott, N.J.3
  • 7
    • 0033783241 scopus 로고    scopus 로고
    • Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets
    • Clarke H, Soler AP, and Mullin JM. Protein kinase C activation leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets. J Cell Sci 113: 3187-3196, 2000.
    • (2000) J Cell Sci , vol.113 , pp. 3187-3196
    • Clarke, H.1    Soler, A.P.2    Mullin, J.M.3
  • 8
    • 0022332365 scopus 로고
    • Morphometric analysis of CNS microvascular endothelium
    • Coomber BL and Stewart PA. Morphometric analysis of CNS microvascular endothelium. Microvasc Res 30: 99-115, 1985.
    • (1985) Microvasc Res , vol.30 , pp. 99-115
    • Coomber, B.L.1    Stewart, P.A.2
  • 10
    • 0019523265 scopus 로고
    • Electrical resistance of a capillary endothelium
    • Crone C and Christensen O. Electrical resistance of a capillary endothelium. J Gen Physiol 77: 349-371, 1981.
    • (1981) J Gen Physiol , vol.77 , pp. 349-371
    • Crone, C.1    Christensen, O.2
  • 12
    • 0031825437 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
    • Esser S, Lampugnani MG, Corada M, Dejana E, and Risau W. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J Cell Sci 111: 1853-1865, 1998.
    • (1998) J Cell Sci , vol.111 , pp. 1853-1865
    • Esser, S.1    Lampugnani, M.G.2    Corada, M.3    Dejana, E.4    Risau, W.5
  • 13
    • 0000752197 scopus 로고
    • Junctional complexes in various epithlia
    • Faquhar MG and PGE. Junctional complexes in various epithlia. J Cell Biol 375-412, 1963.
    • (1963) J Cell Biol , pp. 375-412
    • Faquhar, M.G.1
  • 14
    • 0032792058 scopus 로고    scopus 로고
    • Redistribution and phosphorylation of occludin during opening and resealing of tight junctions in cultured epithelial cells
    • Farshori P and Kachar B. Redistribution and phosphorylation of occludin during opening and resealing of tight junctions in cultured epithelial cells. J Membr Biol 170: 147-156, 1999.
    • (1999) J Membr Biol , vol.170 , pp. 147-156
    • Farshori, P.1    Kachar, B.2
  • 15
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse M, Fujita K, Hiiragi T, Fujimoto K, and Tsukita S. Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141: 1539-1550, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, S.5
  • 16
  • 17
    • 0028110309 scopus 로고
    • Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
    • Furuse M, Itoh M, Hirase T, Nagafuchi A, Yonemura S, and Tsukita S. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J Cell Biol 127: 1617-1626, 1994.
    • (1994) J Cell Biol , vol.127 , pp. 1617-1626
    • Furuse, M.1    Itoh, M.2    Hirase, T.3    Nagafuchi, A.4    Yonemura, S.5    Tsukita, S.6
  • 18
    • 0018901526 scopus 로고
    • Rapid simultaneous determination of regional blood flow and blood-brain glucose transfer in brain of rat
    • Gjedde A, Hansen AJ, and Siemkowicz E. Rapid simultaneous determination of regional blood flow and blood-brain glucose transfer in brain of rat. Acta Physiol Scand 108: 321-330, 1980.
    • (1980) Acta Physiol Scand , vol.108 , pp. 321-330
    • Gjedde, A.1    Hansen, A.J.2    Siemkowicz, E.3
  • 19
    • 0031590412 scopus 로고    scopus 로고
    • Interleukin-1 modulates protein tyrosine phosphatase activity and permeability of brain endothelial cells
    • Gloor SM, Weber A, Adachi N, and Frei K. Interleukin-1 modulates protein tyrosine phosphatase activity and permeability of brain endothelial cells. Biochem Biophys Res Commun 239: 804-809, 1997.
    • (1997) Biochem Biophys Res Commun , vol.239 , pp. 804-809
    • Gloor, S.M.1    Weber, A.2    Adachi, N.3    Frei, K.4
  • 21
    • 0034464601 scopus 로고    scopus 로고
    • High altitude cerebral edema and acute mountain sickness. A pathophysiology update
    • Hackett PH. High altitude cerebral edema and acute mountain sickness. A pathophysiology update. Adv Exp Med Biol 474: 23-45, 1999.
    • (1999) Adv Exp Med Biol , vol.474 , pp. 23-45
    • Hackett, P.H.1
  • 22
    • 84979102148 scopus 로고
    • Effects of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow autoregulation in dogs
    • Haggendal E and Johansson B. Effects of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow autoregulation in dogs. Acta Physiol Scand Suppl 258: 27-53, 1965.
    • (1965) Acta Physiol Scand Suppl , vol.258 , pp. 27-53
    • Haggendal, E.1    Johansson, B.2
  • 23
    • 0032489875 scopus 로고    scopus 로고
    • ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
    • Haskins J, Gu L, Wittchen ES, Hibbard J, and Stevenson BR. ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J Cell Biol 141: 199-208, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 199-208
    • Haskins, J.1    Gu, L.2    Wittchen, E.S.3    Hibbard, J.4    Stevenson, B.R.5
  • 24
    • 0025319983 scopus 로고
    • Brain edema and cerebrovascular permeability during cerebral ischemia in rats
    • Hatashita S and Hoff JT. Brain edema and cerebrovascular permeability during cerebral ischemia in rats. Stroke 21: 582-588, 1990.
    • (1990) Stroke , vol.21 , pp. 582-588
    • Hatashita, S.1    Hoff, J.T.2
  • 25
    • 0035971219 scopus 로고    scopus 로고
    • Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms
    • Hirase T, Kawashima S, Wong EY, Ueyama T, Rikitake Y, Tsukita S, Yokoyama M, and Staddon JM. Regulation of tight junction permeability and occludin phosphorylation by Rhoa-p160ROCK-dependent and -independent mechanisms. J Biol Chem 276: 10423-10431, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 10423-10431
    • Hirase, T.1    Kawashima, S.2    Wong, E.Y.3    Ueyama, T.4    Rikitake, Y.5    Tsukita, S.6    Yokoyama, M.7    Staddon, J.M.8
  • 27
    • 0035576934 scopus 로고    scopus 로고
    • Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier
    • Huber JD, Egleton RD, and Davis TP. Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier. Trends Neurosci 24: 719-725, 2001.
    • (2001) Trends Neurosci , vol.24 , pp. 719-725
    • Huber, J.D.1    Egleton, R.D.2    Davis, T.P.3
  • 29
    • 0030748548 scopus 로고    scopus 로고
    • Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments
    • Itoh M, Nagafuchi A, Moroi S, and Tsukita S. Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to alpha catenin and actin filaments. J Cell Biol 138: 181-192, 1997.
    • (1997) J Cell Biol , vol.138 , pp. 181-192
    • Itoh, M.1    Nagafuchi, A.2    Moroi, S.3    Tsukita, S.4
  • 30
    • 0015980960 scopus 로고
    • Blood flow and oxygen consumption of the rat brain in profound hypoxia
    • Johannsson H and Siesjo BK. Blood flow and oxygen consumption of the rat brain in profound hypoxia. Acta Physiol Scand 90: 281-282, 1974.
    • (1974) Acta Physiol Scand , vol.90 , pp. 281-282
    • Johannsson, H.1    Siesjo, B.K.2
  • 31
    • 0016732013 scopus 로고
    • Cerebral blood flow and oxygen consumption in the rat in hypoxic hypoxia
    • Johannsson H and Siesjo BK. Cerebral blood flow and oxygen consumption in the rat in hypoxic hypoxia. Acta Physiol Scand 93: 269-276, 1975.
    • (1975) Acta Physiol Scand , vol.93 , pp. 269-276
    • Johannsson, H.1    Siesjo, B.K.2
  • 33
    • 0033973460 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier
    • Kniesel U and Wolburg H. Tight junctions of the blood-brain barrier. Cell Mol Neurobiol 20: 57-76, 2000.
    • (2000) Cell Mol Neurobiol , vol.20 , pp. 57-76
    • Kniesel, U.1    Wolburg, H.2
  • 34
    • 0002738930 scopus 로고    scopus 로고
    • Cerebral hemodynamics and high altitude cerebral edema
    • edited by Houston C and Coates G. Burlington, VT: Queen City Printers
    • Krasney J. Cerebral hemodynamics and high altitude cerebral edema. In: Hypoxia: Women at Altitude, edited by Houston C and Coates G. Burlington, VT: Queen City Printers, 1997, p. 254-268.
    • (1997) Hypoxia: Women at Altitude , pp. 254-268
    • Krasney, J.1
  • 35
    • 0028040040 scopus 로고
    • A neurogenic basis for acute altitude illness
    • Krasney JA. A neurogenic basis for acute altitude illness. Med Sci Sports Exerc 26: 195-208, 1994.
    • (1994) Med Sci Sports Exerc , vol.26 , pp. 195-208
    • Krasney, J.A.1
  • 36
    • 0016844941 scopus 로고
    • High-altitude cerebral oedema
    • Lassen NA and Harper AM. High-altitude cerebral oedema (Letter). Lancet 2: 1154, 1975.
    • (1975) Lancet , vol.2 , pp. 1154
    • Lassen, N.A.1    Harper, A.M.2
  • 37
    • 0034465468 scopus 로고    scopus 로고
    • Dynamic cerebral autoregulation at high altitude
    • edited by Roach RC, Wagner PD, and Hackett PH. New York: Kluwer Academic/Plenum
    • Levine BD, Zhang R, and Roach RC. Dynamic cerebral autoregulation at high altitude. In: Hypoxia: Into the Next Millenium, edited by Roach RC, Wagner PD, and Hackett PH. New York: Kluwer Academic/Plenum, 1999, p. 319-322.
    • (1999) Hypoxia: Into the Next Millenium , pp. 319-322
    • Levine, B.D.1    Zhang, R.2    Roach, R.C.3
  • 39
    • 0026578796 scopus 로고
    • Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms
    • Lum H, Barr DA, Shaffer JR, Gordon RJ, Ezrin AM, and Malik AB. Reoxygenation of endothelial cells increases permeability by oxidant-dependent mechanisms. Circ Res 70: 991-998, 1992.
    • (1992) Circ Res , vol.70 , pp. 991-998
    • Lum, H.1    Barr, D.A.2    Shaffer, J.R.3    Gordon, R.J.4    Ezrin, A.M.5    Malik, A.B.6
  • 40
    • 0036084919 scopus 로고    scopus 로고
    • Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation
    • Mark KS and Davis TP. Cerebral microvascular changes in permeability and tight junctions induced by hypoxia-reoxygenation. Am J Physiol Heart Circ Physiol 282: H1485-H1494, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Mark, K.S.1    Davis, T.P.2
  • 41
    • 0031944250 scopus 로고    scopus 로고
    • Molecular architecture of tight junctions
    • Mitic LL and Anderson JM. Molecular architecture of tight junctions. Annu Rev Physiol 60: 121-142, 1998.
    • (1998) Annu Rev Physiol , vol.60 , pp. 121-142
    • Mitic, L.L.1    Anderson, J.M.2
  • 43
    • 0026338562 scopus 로고
    • The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells
    • Nigam SK, Denisenko N, Rodriguez-Boulan E, and Citi S. The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells. Biochem Biophys Res Commun 181: 548-553, 1991.
    • (1991) Biochem Biophys Res Commun , vol.181 , pp. 548-553
    • Nigam, S.K.1    Denisenko, N.2    Rodriguez-Boulan, E.3    Citi, S.4
  • 44
    • 0016711099 scopus 로고
    • Greater number of capillary endothelial cell mitochondria in brain than in muscle
    • Oldendorf WH and Brown WJ. Greater number of capillary endothelial cell mitochondria in brain than in muscle. Proc Soc Exp Biol Med 149: 736-738, 1975.
    • (1975) Proc Soc Exp Biol Med , vol.149 , pp. 736-738
    • Oldendorf, W.H.1    Brown, W.J.2
  • 45
    • 0017487289 scopus 로고
    • The large apparent work capability of the blood-brain barrier: A study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat
    • Oldendorf WH, Cornford ME, and Brown WJ. The large apparent work capability of the blood-brain barrier: a study of the mitochondrial content of capillary endothelial cells in brain and other tissues of the rat. Ann Neurol 1: 409-417, 1977.
    • (1977) Ann Neurol , vol.1 , pp. 409-417
    • Oldendorf, W.H.1    Cornford, M.E.2    Brown, W.J.3
  • 47
    • 0020956774 scopus 로고
    • Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data
    • Patlak CS, Blasberg RG, and Fenstermacher JD. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 3: 1-7, 1983.
    • (1983) J Cereb Blood Flow Metab , vol.3 , pp. 1-7
    • Patlak, C.S.1    Blasberg, R.G.2    Fenstermacher, J.D.3
  • 48
    • 0037648757 scopus 로고    scopus 로고
    • Brain oedema following blood-brain barrier disruption: Mechanisms and diagnosis
    • Payen JF, Fauvage B, Falcon D, and Lavagne P. [Brain oedema following blood-brain barrier disruption: mechanisms and diagnosis]. Ann Fr Anesth Reanim 22: 220-225, 2003.
    • (2003) Ann Fr Anesth Reanim , vol.22 , pp. 220-225
    • Payen, J.F.1    Fauvage, B.2    Falcon, D.3    Lavagne, P.4
  • 49
    • 0028822474 scopus 로고
    • Hypoxia increases the susceptibility to oxidant stress and the permeability of the blood-brain barrier endothelial cell monolayer
    • Plateel M, Dehouck MP, Torpier G, Cecchelli R, and Teissier E. Hypoxia increases the susceptibility to oxidant stress and the permeability of the blood-brain barrier endothelial cell monolayer. J Neurochem 65: 2138-2145, 1995.
    • (1995) J Neurochem , vol.65 , pp. 2138-2145
    • Plateel, M.1    Dehouck, M.P.2    Torpier, G.3    Cecchelli, R.4    Teissier, E.5
  • 51
    • 0014109002 scopus 로고
    • Fine structural localization of a blood-brain barrier to exogenous peroxidase
    • Reese TS and Karnovsky MJ. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 34: 207-217, 1967.
    • (1967) J Cell Biol , vol.34 , pp. 207-217
    • Reese, T.S.1    Karnovsky, M.J.2
  • 53
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • Rothman SM and Olney JW. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann Neurol 19: 105-111, 1986.
    • (1986) Ann Neurol , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 54
    • 0019798461 scopus 로고
    • Simultaneous measurement of cerebral blood flow and unidirectional movement of substances across the blood-brain barrier: Theory, method, and application to leucine
    • Sage JI, Van Uitert RL, and Duffy TE. Simultaneous measurement of cerebral blood flow and unidirectional movement of substances across the blood-brain barrier: theory, method, and application to leucine. J Neurochem 36: 1731-1738, 1981.
    • (1981) J Neurochem , vol.36 , pp. 1731-1738
    • Sage, J.I.1    Van Uitert, R.L.2    Duffy, T.E.3
  • 55
    • 0030982357 scopus 로고    scopus 로고
    • Possible involvement of phosphorylation of occludin in tight junction formation
    • Sakakibara A, Furuse M, Saitou M, Ando-Akatsuka Y, and Tsukita S. Possible involvement of phosphorylation of occludin in tight junction formation. J Cell Biol 137: 1393-1401, 1997.
    • (1997) J Cell Biol , vol.137 , pp. 1393-1401
    • Sakakibara, A.1    Furuse, M.2    Saitou, M.3    Ando-Akatsuka, Y.4    Tsukita, S.5
  • 56
    • 0028322134 scopus 로고
    • Relationship of serine/threonine phosphorylation/dephosphorylation signaling to glucocorticoid regulation of tight junction permeability and ZO-1 distribution in nontransformed mammary epithelial cells
    • Singer KL, Stevenson BR, Woo PL, and Firestone GL. Relationship of serine/threonine phosphorylation/dephosphorylation signaling to glucocorticoid regulation of tight junction permeability and ZO-1 distribution in nontransformed mammary epithelial cells. J Biol Chem 269: 16108-16115, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 16108-16115
    • Singer, K.L.1    Stevenson, B.R.2    Woo, P.L.3    Firestone, G.L.4
  • 58
    • 0028931103 scopus 로고
    • Evidence that tyrosine phosphorylation may increase tight junction permeability
    • Staddon JM, Herrenknecht K, Smales C, and Rubin LL. Evidence that tyrosine phosphorylation may increase tight junction permeability. J Cell Sci 108: 609-619, 1995.
    • (1995) J Cell Sci , vol.108 , pp. 609-619
    • Staddon, J.M.1    Herrenknecht, K.2    Smales, C.3    Rubin, L.L.4
  • 59
    • 0018691704 scopus 로고
    • Pathophysiology of acute mountain sickness and high-altitude pulmonary oedema: An hypothesis
    • Sutton JR and Lassen N. Pathophysiology of acute mountain sickness and high-altitude pulmonary oedema: an hypothesis. Bull Physiopathol Respir (Nancy) 15: 1045-1052, 1979.
    • (1979) Bull Physiopathol Respir (Nancy) , vol.15 , pp. 1045-1052
    • Sutton, J.R.1    Lassen, N.2
  • 60
    • 0022586446 scopus 로고
    • Regional cerebral glucose metabolic rate during thirty minutes hypoxia of 7% oxygen in adult conscious rats
    • Torbati D, Greenberg JH, and Lambertsen CJ. Regional cerebral glucose metabolic rate during thirty minutes hypoxia of 7% oxygen in adult conscious rats. Neurosci Lett 65: 253-258, 1986.
    • (1986) Neurosci Lett , vol.65 , pp. 253-258
    • Torbati, D.1    Greenberg, J.H.2    Lambertsen, C.J.3
  • 61
    • 0025295847 scopus 로고
    • Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins
    • Triguero D, Buciak J, and Pardridge WM. Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins. J Neurochem 54: 1882-1888, 1990.
    • (1990) J Neurochem , vol.54 , pp. 1882-1888
    • Triguero, D.1    Buciak, J.2    Pardridge, W.M.3
  • 62
    • 0034599992 scopus 로고    scopus 로고
    • Pores in the wall: Claudins constitute tight junction strands containing aqueous pores
    • Tsukita S and Furuse M. Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol 149: 13-16, 2000.
    • (2000) J Cell Biol , vol.149 , pp. 13-16
    • Tsukita, S.1    Furuse, M.2
  • 63
    • 0030983484 scopus 로고    scopus 로고
    • Occludin confers adhesiveness when expressed in fibroblasts
    • Van Itallie CM and Anderson JM. Occludin confers adhesiveness when expressed in fibroblasts. J Cell Sci 110: 1113-1121, 1997.
    • (1997) J Cell Sci , vol.110 , pp. 1113-1121
    • Van Itallie, C.M.1    Anderson, J.M.2
  • 64
    • 0030051010 scopus 로고    scopus 로고
    • Effects of hypoxia-ischemia on GLUT1 and GLUT3 glucose transporters in immature rat brain
    • Vannucci SJ, Seaman LB, and Vannucci RC. Effects of hypoxia-ischemia on GLUT1 and GLUT3 glucose transporters in immature rat brain. J Cereb Blood Flow Metab 16: 77-81, 1996.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 77-81
    • Vannucci, S.J.1    Seaman, L.B.2    Vannucci, R.C.3
  • 65
    • 0027346592 scopus 로고
    • Some aspects of the use of laser Doppler flow meters for recording tissue blood flow
    • Vongsavan N and Matthews B. Some aspects of the use of laser Doppler flow meters for recording tissue blood flow. Exp Physiol 78: 1-14, 1993.
    • (1993) Exp Physiol , vol.78 , pp. 1-14
    • Vongsavan, N.1    Matthews, B.2
  • 66
    • 0033491912 scopus 로고    scopus 로고
    • Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition
    • Wachtel M, Frei K, Ehler E, Fontana A, Winterhalter K, and Gloor SM. Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J Cell Sci 112: 4347-4356, 1999.
    • (1999) J Cell Sci , vol.112 , pp. 4347-4356
    • Wachtel, M.1    Frei, K.2    Ehler, E.3    Fontana, A.4    Winterhalter, K.5    Gloor, S.M.6
  • 67
    • 0036627211 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier: Development, composition and regulation
    • Wolburg H and Lippoldt A. Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 38: 323-337, 2002.
    • (2002) Vascul Pharmacol , vol.38 , pp. 323-337
    • Wolburg, H.1    Lippoldt, A.2
  • 69
    • 0031425958 scopus 로고    scopus 로고
    • Phosphorylation of occludin correlates with occludin localization and function at the tight junction
    • Wong V. Phosphorylation of occludin correlates with occludin localization and function at the tight junction. Am J Physiol Cell Physiol 273: C1859-C1867, 1997.
    • (1997) Am J Physiol Cell Physiol , vol.273
    • Wong, V.1
  • 70
    • 0032843718 scopus 로고    scopus 로고
    • Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension
    • Zaharchuk G, Mandeville JB, Bogdanov AA Jr, Weissleder R, Rosen BR, and Marota JJ. Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension. Stroke 30: 2197-2204; 2204-2205, 1999.
    • (1999) Stroke , vol.30 , pp. 2197-2204
    • Zaharchuk, G.1    Mandeville, J.B.2    Bogdanov Jr., A.A.3    Weissleder, R.4    Rosen, B.R.5    Marota, J.J.6
  • 72
    • 0022527283 scopus 로고
    • Measurement of solute transport across the blood-brain barrier in the perfused guinea pig brain: Method and application to N-methyl-alpha-aminoisobutyric acid
    • Zlokovic BV, Begley DJ, Djuricic BM, and Mitrovic DM. Measurement of solute transport across the blood-brain barrier in the perfused guinea pig brain: method and application to N-methyl-alpha-aminoisobutyric acid. J Neurochem 46: 1444-1451, 1986.
    • (1986) J Neurochem , vol.46 , pp. 1444-1451
    • Zlokovic, B.V.1    Begley, D.J.2    Djuricic, B.M.3    Mitrovic, D.M.4


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