메뉴 건너뛰기




Volumn 23, Issue 3, 2015, Pages 71-78

Vitamin D3 in cancer prevention and therapy: The nutritional issue

Author keywords

cancer; Vitamin D

Indexed keywords

CALCITRIOL; COLECALCIFEROL; CYTOKINE; HORMONE; VITAMIN;

EID: 84957707494     PISSN: 18681883     EISSN: 18681891     Source Type: Journal    
DOI: 10.1515/hmbci-2015-0011     Document Type: Review
Times cited : (13)

References (88)
  • 1
    • 84922985021 scopus 로고    scopus 로고
    • Systematic review and meta-Analysis: Prevalence and possible causes of Vitamin D deficiency and insufficiency in pediatri c cancer patients
    • Revuelta Iniesta R, Rush R, Paciarotti I, Rhatigan EB, Brougham FH, McKenzie JM, Wilson DC. Systematic review and meta-Analysis: prevalence and possible causes of vitamin D deficiency and insufficiency in pediatri c cancer patients. Clin Nutr 2015; doi: 10.1016/j. clnu.2014.12.023.
    • (2015) Clin Nutr
    • Revuelta Iniesta, R.1    Rush, R.2    Paciarotti, I.3    Rhatigan, E.B.4    Brougham, F.H.5    McKenzie, J.M.6    Wilson, D.C.7
  • 2
    • 84928255074 scopus 로고    scopus 로고
    • The relationship of Vitamin D status to risk of cardiovascular disease and mortality
    • Skaaby T. The relationship of vitamin D status to risk of cardiovascular disease and mortality. Dan Med J 2015;61:pii: B5008.
    • (2015) Dan Med J , vol.61
    • Skaaby, T.1
  • 4
    • 84866353183 scopus 로고    scopus 로고
    • Circulating 25-hydroxyvitamin d concentration and the risk of type 2 diab etes: Results from the european prospective investigation into cancer (epic)-norfolk cohort and updated meta-Analysis of prospective studies
    • Forouhi NG, Ye Z, Rickard AP, Khaw KT, Luben R, Langenberg C, Wareham NJ. Circulating 25-hydroxyvitamin D concentration and the risk of type 2 diab etes: results from the European Prospective Investigation into Cancer (EPIC)-Norfolk cohort and updated meta-Analysis of prospective studies. Diabetologia 2012;55:2173-82.
    • (2012) Diabetologia , vol.55 , pp. 2173-2182
    • Forouhi, N.G.1    Ye, Z.2    Rickard, A.P.3    Khaw, K.T.4    Luben, R.5    Langenberg, C.6    Wareham, N.J.7
  • 5
    • 84879800751 scopus 로고    scopus 로고
    • Plasma Vitamin D levels, menopause, and risk of breast cancer: Doseresponse meta-Analysis of prospective studies
    • Bauer SR,Hankinson SE,Bert one-Johnson ER,Ding EL. Plasma vitamin D levels, menopause, and risk of breast cancer: doseresponse meta-Analysis of prospective studies Medicine ( Baltimore 2013 92, 123-31.
    • (2013) Medicine ( Baltimore , vol.92 , pp. 123-131
    • Bauer, S.R.1    Hankinson, S.E.2    Bertone-Johnson, E.R.3    Ding, E.L.4
  • 6
    • 84925545290 scopus 로고    scopus 로고
    • Vitamin-d status at breast cancer diagnosis: Correlation with social and environmental factors and dietary intake
    • Imtiaz S, Siddiqui N. Vitamin-D status at breast cancer diagnosis: correlation with social and environmental factors and dietary intake. J Ayub Med Coll Abbottabad 2014;26:186-90.
    • (2014) J Ayub Med Coll Abbottabad , vol.26 , pp. 186-190
    • Imtiaz, S.1    Siddiqui, N.2
  • 7
    • 84926970639 scopus 로고    scopus 로고
    • The prevalence of Vitamin D deficiency is higher in adult survivors of childhood cancer
    • Neville KA, Walker JL, Cohn RJ, Cowell CT, White CP. The Prevalence of Vitamin D deficiency is higher in adult survivors of childhood cancer. Clin Endocrinol (Oxf) 2015;82:657-62.
    • (2015) Clin Endocrinol (Oxf , vol.82 , pp. 657-662
    • Neville, K.A.1    Walker, J.L.2    Cohn, R.J.3    Cowell, C.T.4    White, C.P.5
  • 8
    • 84922402224 scopus 로고    scopus 로고
    • Hypovitaminosis d a common deficiency with pervasive consequences
    • Podd D. Hypovitaminosis D: a common deficiency with pervasive consequences. J Am Acad Physician Assist 2015;28:20-6.
    • (2015) J Am Acad Physician Assist , vol.28 , pp. 20-26
    • Podd, D.1
  • 9
    • 84923276391 scopus 로고    scopus 로고
    • Vitamin D supplementation and health-related quality of life: A systematic review of the literature
    • Hoffmann MR, Senior PA, Mager DR. Vitamin D supplementation and health-related quality of life: a systematic review of the literature. J Acad Nutr Diet 2015;115:406-18.
    • (2015) J Acad Nutr Diet , vol.115 , pp. 406-418
    • Hoffmann, M.R.1    Senior, P.A.2    Mager, D.R.3
  • 11
    • 0028019547 scopus 로고
    • Mammary ductal epithelial cell hyperproliferation and hyperplasia induced by a nutritional stress diet containin g four components of a western-style diet
    • Khan N, Yang K, Newmark H, Wong G, Telang N, Rivlin R, Lipkin M. Mammary ductal epithelial cell hyperproliferation and hyperplasia induced by a nutritional stress diet containin g four components of a western-style diet. Carcinogenesis 1994;15:2645-8.
    • (1994) Carcinogenesis , vol.15 , pp. 2645-2648
    • Khan, N.1    Yang, K.2    Newmark, H.3    Wong, G.4    Telang, N.5    Rivlin, R.6    Lipkin, M.7
  • 12
    • 46749132318 scopus 로고    scopus 로고
    • Effect of a western-style diet fortified with increased calcium a nd Vitamin D on mammary gland of c57bl/6 mice
    • Kurihara N, Fan K, Thaler HT, Yang K, Lipkin M. Effect of a Western-style diet fortified with increased calcium a nd vitamin D on mammary gland of C57BL/6 mice. J Med Food 2008;11: 201-6.
    • (2008) J Med Food , vol.11 , pp. 201-206
    • Kurihara, N.1    Fan, K.2    Thaler, H.T.3    Yang, K.4    Lipkin, M.5
  • 13
    • 0028556513 scopus 로고
    • Vitamin D adequacy: A possible relationship to breast cancer
    • Newmark HL. Vitamin D adequacy: a possible relationship to breast cancer. Adv Exp Med Biol 1994;364:109-14.
    • (1994) Adv Exp Med Biol , vol.364 , pp. 109-114
    • Newmark, H.L.1
  • 15
    • 84922146531 scopus 로고    scopus 로고
    • Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer
    • Irving AA, Plum LA, Blaser WJ, Ford MR, Weng C, Clipson L, DeLuca HF, Dove WF. Cholecalciferol or 25-hydroxycholecalciferol neither prevents nor treats adenomas in a rat model of familial colon cancer. J Nutr 2015;145:291-8.
    • (2015) J Nutr , vol.145 , pp. 291-298
    • Irving, A.A.1    Plum, L.A.2    Blaser, W.J.3    Ford, M.R.4    Weng, C.5    Clipson, L.6    DeLuca, H.F.7    Dove, W.F.8
  • 16
    • 0034446449 scopus 로고    scopus 로고
    • A protective role of dietary vitamin d3 in rat colon carcinogenesis
    • Mokady E, Schwartz B, Shany S, Lamprecht SA. A protective role of dietary vitamin D3 in rat colon carcinogenesis. Nutr Cancer 2000;38:65-73.
    • (2000) Nutr Cancer , vol.38 , pp. 65-73
    • Mokady, E.1    Schwartz, B.2    Shany, S.3    Lamprecht, S.A.4
  • 20
    • 84907163236 scopus 로고    scopus 로고
    • Sunlight ultraviolet radiation Vitamin D and skin cancer: How much sunlight do we need?
    • Holick MF. Sunlight, ultraviolet radiation, vitamin D and skin cancer: how much sunlight do we need? Adv Exp Med Biol 2014;810:1-16.
    • (2014) Adv Exp Med Biol , vol.810 , pp. 1-16
    • Holick, M.F.1
  • 21
    • 84907168852 scopus 로고    scopus 로고
    • Optimal serum 25-hydroxyvitamin d levels for multiple health outcomes
    • Bischoff-Ferrari HA. Optimal serum 25-hydroxyvitamin D levels for multiple health outcomes. Adv Exp Med Biol 2014;810:500-25.
    • (2014) Adv Exp Med Biol , vol.810 , pp. 500-525
    • Bischoff-Ferrari, H.A.1
  • 22
    • 84904870926 scopus 로고    scopus 로고
    • Are low levels of Vitamin D causes of disease-or just indicators of poor lifestyle choices that can foster disease? There's no clear answer yet
    • Sunshine in a bottle: continuing debate over vitamin D supplements
    • Sunshine in a bottle: continuing debate over vitamin D supplements. Are low levels of vitamin D causes of disease-or just indicators of poor lifestyle choices that can foster disease? There's no clear answer yet. Duke Med Health News 20 14;20:4-5.
    • (2014) Duke Med Health News , vol.20 , pp. 4-5
  • 23
    • 79951782445 scopus 로고    scopus 로고
    • 1,25-DihydroxyVitamin D3 acts directly on the T lymphocyte Vitamin D receptor to inhibit experimental autoimmune encephalomyeliti s
    • Mayne CG, Spanier JA, Relland LM, Williams CB, Hayes CE. 1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyeliti s. Eur J Immunol 2011;41:822-32.
    • (2011) Eur J Immunol , vol.41 , pp. 822-832
    • Mayne, C.G.1    Spanier, J.A.2    Relland, L.M.3    Williams, C.B.4    Hayes, C.E.5
  • 25
    • 84901506266 scopus 로고    scopus 로고
    • The Vitamin D receptor turns off chronically activated t cells
    • Cantorna MT, Waddell A. The vitamin D receptor turns off chronically activated T cells. Ann N Y Acad Sci 2014;1317:70-5.
    • (2014) Ann N y Acad Sci , vol.1317 , pp. 70-75
    • Cantorna, M.T.1    Waddell, A.2
  • 26
    • 84893662446 scopus 로고    scopus 로고
    • Vitamin D receptor expression controls proliferation of naïve cd8+ t cells and development of cd8 mediated gastrointestinal inflammation
    • Chen J,Bruce D,Cantorna MT. Vitamin D receptor expression controls proliferation of naïve CD8+ T cells and development of CD8 mediated gastrointestinal inflammation BMC Immunol 2014 15, 6.
    • (2014) BMC Immunol , vol.15 , pp. 6
    • Chen, J.1    Bruce, D.2    Cantorna, M.T.3
  • 27
    • 79251550435 scopus 로고    scopus 로고
    • Why do t cells express the Vitamin D receptor?
    • Cantorna MT. Why do T cells express the vitamin D receptor? Ann N Y Acad Sci 2011;1217:77-82.
    • (2011) Ann N y Acad Sci , vol.1217 , pp. 77-82
    • Cantorna, M.T.1
  • 31
    • 84894677493 scopus 로고    scopus 로고
    • Association between vdr polymorphisms and breast cancer: An updated and comparative meta-Analysis of cru de and adjusted odd ratios
    • Huang QQ, Liao YY, Ye XH, Fu JJ, Chen SD. Association between VDR polymorphisms and breast cancer: an updated and comparative meta-Analysis of cru de and adjusted odd ratios. Asian Pac J Cancer Prev 2014;15:847-53.
    • (2014) Asian Pac J Cancer Prev , vol.15 , pp. 847-853
    • Huang, Q.Q.1    Liao, Y.Y.2    Ye, X.H.3    Fu, J.J.4    Chen, S.D.5
  • 32
    • 84977134566 scopus 로고    scopus 로고
    • Inkt/cd1d-Antitumor immunotherapy significantly increases th e efficacy of therapeutic cpg/peptide-based cancer vaccine
    • Corgnac S, Perret R, Zhang L, Mach JP, Romero P, Donda A. iNKT/CD1d-Antitumor immunotherapy significantly increases th e efficacy of therapeutic CpG/peptide-based cancer vaccine. J Immunother Cancer 2014;2:39.
    • (2014) J Immunother Cancer , vol.2 , pp. 39
    • Corgnac, S.1    Perret, R.2    Zhang, L.3    Mach, J.P.4    Romero, P.5    Donda, A.6
  • 33
    • 42449108137 scopus 로고    scopus 로고
    • The Vitamin D receptor is required for inkt cell development
    • Yu S, Cantorna MT. The vitamin D receptor is required for iNKT cell development. Proc Natl Acad Sci USA 2008;105:5207-12.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5207-5212
    • Yu, S.1    Cantorna, M.T.2
  • 34
    • 79960444343 scopus 로고    scopus 로고
    • Anti-tumor immune responses induced by inkt cell-based immunotherapy for lung cancer and head and neck cancer
    • Motohashi S, Okamoto Y, Yoshino I, Nakayama T. Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer. Clin Immunol 2011;140:167-76.
    • (2011) Clin Immunol , vol.140 , pp. 167-176
    • Motohashi, S.1    Okamoto, Y.2    Yoshino, I.3    Nakayama, T.4
  • 37
    • 84894538861 scopus 로고    scopus 로고
    • Invariant nkt cells: Killers and conspirators against cancer
    • Bassiri H, Das R, Nichols KE. Invariant NKT cells: killers and conspirators against cancer. Oncoimmunology 2013;2:e27440.
    • (2013) Oncoimmunology , vol.2 , pp. e27440
    • Bassiri, H.1    Das, R.2    Nichols, K.E.3
  • 38
    • 65649111531 scopus 로고    scopus 로고
    • Invariant natural killer t cells: Innate-like t cells with potent immunomodulatory activities
    • Wu L, Gabriel CL, Parekh VV, Van Kaer L. Invariant natural killer T cells: innate-like T cells with potent immunomodulatory activities. Tissue Antigens 2009;73:535-45.
    • (2009) Tissue Antigens , vol.73 , pp. 535-545
    • Wu, L.1    Gabriel, C.L.2    Parekh, V.V.3    Van Kaer, L.4
  • 40
    • 84912017977 scopus 로고    scopus 로고
    • V itamin d receptor signals regulate effector and memory cd8 t cell responses to infections in mice
    • Yuzefpolskiy Y, Baumann FM, Penny LA, Studzinski GP, Kalia V, Sarkar S. V itamin D receptor signals regulate effector and memory CD8 T cell responses to infections in mice. J Nutr 2014;144: 2073-82.
    • (2014) J Nutr , vol.144 , pp. 2073-2082
    • Yuzefpolskiy, Y.1    Baumann, F.M.2    Penny, L.A.3    Studzinski, G.P.4    Kalia, V.5    Sarkar, S.6
  • 41
    • 84924405606 scopus 로고    scopus 로고
    • Vitamin D(3metabolites enhance the nlrp3-dependent secretion of il-1? from human thp-1 monocytic cells
    • Tulk SE, Liao KC, Muruve DA, Li Y, Beck PL, MacDonald JA. Vitamin D(3) metabolites enhance the NLRP3-dependent secretion of IL-1? from human THP-1 monocytic cells. J Cell Biochem 2015;116:711-20.
    • (2015) J Cell Biochem , vol.116 , pp. 711-720
    • Tulk, S.E.1    Liao, K.C.2    Muruve, D.A.3    Li, Y.4    Beck, P.L.5    MacDonald, J.A.6
  • 42
    • 84891922851 scopus 로고    scopus 로고
    • 1 Alpha, 25-dihydroxylvitamin d3 promotes bacillus calmette-guérin immunotherapy of bladder cancer
    • Hsu JW, Yin PN, Wood R, Messing J, Messing E, Lee YF. 1 alpha, 25-dihydroxylvitamin D3 promotes Bacillus Calmette-Guérin immunotherapy of bladder cancer. Oncotarget 2013;4: 2397-406.
    • (2013) Oncotarget , vol.4 , pp. 2397-2406
    • Hsu, J.W.1    Yin, P.N.2    Wood, R.3    Messing, J.4    Messing, E.5    Lee, Y.F.6
  • 43
    • 36849085584 scopus 로고    scopus 로고
    • Immunotherapy of metastatic breast cancer patients with Vitamin D-binding protein-derived macrophage activating factor (gcmaf)
    • Yamamoto N, Suyama H, Yamamoto N, Ushijima N. Immunotherapy of metastatic breast cancer patients with vitamin D-binding protein-derived macrophage activating factor (GcMAF). Int J Cancer 2008;122:4 61-7.
    • (2008) Int J Cancer , vol.122 , pp. 461-467
    • Yamamoto, N.1    Suyama, H.2    Yamamoto, N.3    Ushijima, N.4
  • 44
    • 42649110411 scopus 로고    scopus 로고
    • Immunotherapy of metastatic colorectal cancer with Vitamin D-binding protein-derived macrophage-Activating factor gcmaf
    • Yamamoto N, Suyama H, Nakazato H, Yamamoto N, Koga Y. Immunotherapy of metastatic colorectal cancer with vitamin D-binding protein-derived macrophage-Activating factor, GcMAF. Cancer Immunol Immuno ther 2008;57:1007-16.
    • (2008) Cancer Immunol Immuno Ther , vol.57 , pp. 1007-1016
    • Yamamoto, N.1    Suyama, H.2    Nakazato, H.3    Yamamoto, N.4    Koga, Y.5
  • 45
    • 84883818341 scopus 로고    scopus 로고
    • Vitamin D therapy and related metabolomics: Is the calciferol dose and form the only requirements f or successful clinical therapeutics?
    • Braithwaite MC, Kumar P, Tyagi C, Tomar LK, Choonara YE, Pillay V. Vitamin D therapy and related metabolomics: is the calciferol dose and form the only requirements f or successful clinical therapeutics? Med Hypotheses 2013;81:656-63.
    • (2013) Med Hypotheses , vol.81 , pp. 656-663
    • Braithwaite, M.C.1    Kumar, P.2    Tyagi, C.3    Tomar, L.K.4    Choonara, Y.E.5    Pillay, V.6
  • 46
    • 84920083874 scopus 로고    scopus 로고
    • The Vitamin D receptor inhibits the respiratory chain, contributing to the metabolic switch that is essential for cancer cell proliferation
    • Consiglio M, Destefanis M, Morena D, Foglizzo V, Forneris M, Pescarmona G, Silvagno F. The vitamin D receptor inhibits the respiratory chain, contributing to the metabolic switch that is essential for cancer cell proliferation. PLoS One 2014;9:e115816.
    • (2014) PLoS One , vol.9 , pp. e115816
    • Consiglio, M.1    Destefanis, M.2    Morena, D.3    Foglizzo, V.4    Forneris, M.5    Pescarmona, G.6    Silvagno, F.7
  • 47
    • 79751471302 scopus 로고    scopus 로고
    • The role of quercetin, flavonols and flavones in modulating inflammatory cell function
    • Chirumbolo S. The role of quercetin, flavonols and flavones in modulating inflammatory cell function Inflamm Allergy Drug Targets 2010, 9, 263-85.
    • (2010) Inflamm Allergy Drug Targets , vol.9 , pp. 263-285
    • Chirumbolo, S.1
  • 48
    • 84884966255 scopus 로고    scopus 로고
    • Novel nonsecosteroidal vdr agonists with phenyl-pyrrolyl pentane skeleton
    • Shen W, Xue J, Zhao Z, Zhang C. Novel nonsecosteroidal VDR agonists with phenyl-pyrrolyl pentane skeleton. Eur J Med Chem 2013;69:768-78.
    • (2013) Eur J Med Chem , vol.69 , pp. 768-778
    • Shen, W.1    Xue, J.2    Zhao, Z.3    Zhang, C.4
  • 49
    • 82255195555 scopus 로고    scopus 로고
    • Apigenin accelerates lipopolysaccharide induced apoptosis in mesenchymal stem cells through suppressing Vitamin D receptor expression
    • Zhang HT, Zha ZG, Cao JH, Liang ZJ, Wu H, He MT, Zang X, Yao P, Zhang JQ. Apigenin accelerates lipopolysaccharide induced apoptosis in mesenchymal stem cells through suppressing vitamin D receptor expression. Chin Med J (Engl) 2011;124:3537-45.
    • (2011) Chin Med J (Engl , vol.124 , pp. 3537-3545
    • Zhang, H.T.1    Zha, Z.G.2    Cao, J.H.3    Liang, Z.J.4    Wu, H.5    He, M.T.6    Zang, X.7    Yao, P.8    Zhang, J.Q.9
  • 50
    • 84901022347 scopus 로고    scopus 로고
    • Impact of Vitamin D on immune function: Lessons learned from genome-wide analysis
    • Chun RF, Liu PT, Modlin RL, Adams JS, Hewison M. Impact of vitamin D on immune function: lessons learned from genome-wide analysis. Front Physiol 2014;5:151.
    • (2014) Front Physiol , vol.5 , pp. 151
    • Chun, R.F.1    Liu, P.T.2    Modlin, R.L.3    Adams, J.S.4    Hewison, M.5
  • 51
    • 84858150326 scopus 로고    scopus 로고
    • Vitamin D metabolism and signaling in the immune system
    • White JH. Vitamin D metabolism and signaling in the immune system. Rev Endocr Metab Disord 2012;13:21-9.
    • (2012) Rev Endocr Metab Disord , vol.13 , pp. 21-29
    • White, J.H.1
  • 52
    • 84861575040 scopus 로고    scopus 로고
    • Regulation of intracrine production of 1,25-dihydroxyvitamin d and its role in innate immune defense against infection
    • White JH. Regulation of intracrine production of 1,25-dihydroxyvitamin D and its role in innate immune defense against infection. Arch Biochem Biophys 2012;523:58-63.
    • (2012) Arch Biochem Biophys , vol.523 , pp. 58-63
    • White, J.H.1
  • 53
    • 84880094789 scopus 로고    scopus 로고
    • A novel role for a major component of the Vitamin D axis: Vitamin D binding protein-derived macrophage activating factor induces human breast cancer cell apoptosis through stimulation of macrophages
    • Thyer L, Ward E, Smith R, Fiore MG, Magherini S, Branca JJ, Morucci G, Gulisano M, Ruggiero M, Pacini S. A novel role for a major component of the vitamin D axis: vitamin D binding protein-derived macrophage activating factor induces human breast cancer cell apoptosis through stimulation of macrophages. Nu trients 2013;5:2577-89.
    • (2013) Nutrients , vol.5 , pp. 2577-2589
    • Thyer, L.1    Ward, E.2    Smith, R.3    Fiore, M.G.4    Magherini, S.5    Branca, J.J.6    Morucci, G.7    Gulisano, M.8    Ruggiero, M.9    Pacini, S.10
  • 54
    • 84906217905 scopus 로고    scopus 로고
    • 1,25-Dyhydroxyvitamin D3 attenuates rotenone-induced neurotoxicity in SH-SY5Y cells through induction of autophagy
    • Jang W, Kim HJ, Li H, Jo KD, Lee MK, Song SH, Yang HO. 1,25-Dyhydroxyvitamin D3 attenuates rotenone-induced neurotoxicity in SH-SY5Y cells through induction of autophagy. Biochem Biophys Res Commun 2014;451:142-7.
    • (2014) Biochem Biophys Res Commun , vol.451 , pp. 142-147
    • Jang, W.1    Kim, H.J.2    Li, H.3    Jo, K.D.4    Lee, M.K.5    Song, S.H.6    Yang, H.O.7
  • 57
    • 84910002431 scopus 로고    scopus 로고
    • Vitamin D suppresses leptin stimulation of cancer growth through microrna
    • Kasiappan R, Sun Y, Lungchukiet P, Quarni W, Zhang X, Bai W. Vitamin D suppresses leptin stimulation of cancer growth through microRNA. Cancer Res 2014;74:6194-204 .
    • (2014) Cancer Res , vol.74 , pp. 6194-6204
    • Kasiappan, R.1    Sun, Y.2    Lungchukiet, P.3    Quarni, W.4    Zhang, X.5    Bai, W.6
  • 58
    • 84915773887 scopus 로고    scopus 로고
    • The multifaceted mechanism of leptin signaling within tumor microenvironment in driving breast cancer growth and progression
    • Andó S, Barone I, Giordano C, Bonofiglio D, Catalano S. The multifaceted mechanism of leptin signaling within tumor microenvironment in driving breast cancer growth and progression. Front Oncol 20 14;4:340.
    • (2014) Front Oncol , Issue.4 , pp. 340
    • Andó, S.1    Barone, I.2    Giordano, C.3    Bonofiglio, D.4    Catalano, S.5
  • 59
    • 84858019563 scopus 로고    scopus 로고
    • Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires ?-catenin activation via akt/gsk3-And mta1/wnt1 proteindependent path ways
    • Yan D, Avtanski D, Saxena NK, Sharma D. Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires ?-catenin activation via Akt/GSK3-And MTA1/Wnt1 proteindependent path ways. J Biol Chem 2012;287:8598-612.
    • (2012) J Biol Chem , vol.287 , pp. 8598-8612
    • Yan, D.1    Avtanski, D.2    Saxena, N.K.3    Sharma, D.4
  • 61
    • 84874775354 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 upregulates leptin expression in mouse adipose tissue
    • Kong J, Chen Y, Zhu G, Zhao Q, Li YC. 1,25-Dihydroxyvitamin D3 upregulates leptin expression in mouse adipose tissue. J Endocrinol 2013;216:265-71.
    • (2013) J Endocrinol , vol.216 , pp. 265-271
    • Kong, J.1    Chen, Y.2    Zhu, G.3    Zhao, Q.4    Li, Y.C.5
  • 63
    • 84905986639 scopus 로고    scopus 로고
    • Leptin promotes metastasis by inducing an epithelialmesenchymal transition in a549 lung cancer cells
    • Feng H, L iu Q, Zhang N, Zheng L, Sang M, Feng J, Zhang J, Wu X, Shan B. Leptin promotes metastasis by inducing an epithelialmesenchymal transition in A549 lung cancer cells. Oncol Res 2013;21:165-71.
    • (2013) Oncol Res , vol.21 , pp. 165-171
    • Feng, H.1    Iu Q, L.2    Zhang, N.3    Zheng, L.4    Sang, M.5    Feng, J.6    Zhang, J.7    Wu, X.8    Shan, B.9
  • 64
    • 34249901328 scopus 로고    scopus 로고
    • The influence of isoflavonoids on the antitumor activity of vitamin d3]
    • (Online). [In Polish]
    • Wietrzyk J. [The influence of isoflavonoids on the antitumor activity of vitamin D3]. Postepy Hig Med Dosw (Online). 2007;61:253-60. [In Polish].
    • (2007) Postepy Hig Med Dosw , vol.61 , pp. 253-260
    • Wietrzyk, J.1
  • 65
    • 0037323184 scopus 로고    scopus 로고
    • Phytoestrogen r egulation of a vitamin d3 receptor promoter and 1,25-dihydroxyvitamin d3 actions in human breast cancer cells
    • Wietzke JA, Welsh J. Phytoestrogen r egulation of a Vitamin D3 receptor promoter and 1,25-dihydroxyvitamin D3 actions in human breast cancer cells. J Steroid Biochem Mol Biol 2003;84:149-57.
    • (2003) J Steroid Biochem Mol Biol , vol.84 , pp. 149-157
    • Wietzke, J.A.1    Welsh, J.2
  • 66
    • 84921494821 scopus 로고    scopus 로고
    • Cutting edge: Progesterone directly upregulates Vitamin D receptor gene expression for efficient regulation of t cells by calcitriol
    • Thangamani S, Kim M, Son Y, Huang X, K im H, Lee JH, Cho J, Ulrich B, Broxmeyer HE, Kim CH. Cutting edge: progesterone directly upregulates vitamin d receptor gene expression for efficient regulation of T cells by calcitriol. J Immunol 2015;194:8 83-6.
    • (2015) J Immunol , vol.194 , pp. 883-886
    • Thangamani, S.1    Kim, M.2    Son, Y.3    Huang, X.4    Im H, K.5    Lee, J.H.6    Cho, J.7    Ulrich, B.8    Broxmeyer, H.E.9    Kim, C.H.10
  • 67
    • 84922019061 scopus 로고    scopus 로고
    • Effects of 17?-estradiol and progesterone on the production of adipokines in differentiating 3t3-l1 adipocytes: Role of rho-kinase
    • Pekta M, Kurt AH, U n A, Tiftik RN, Büyükafar K. Effects of 17?-estradiol and progesterone on the production of adipokines in differentiating 3T3-L1 adipocytes: role of Rho-kinase. Cytokine 2015;72:13 0-4.
    • (2015) Cytokine , vol.72 , pp. 130-134
    • Pekta, M.1    Kurt, A.H.2    Un, A.3    Tiftik, R.N.4    Büyükafar, K.5
  • 68
    • 84902320560 scopus 로고    scopus 로고
    • Vitamin D alters genes involved in follicular development and steroidogenesis in human cumulus granulosa cells
    • Merhi Z, Doswell A, Krebs K, Cipolla M. Vitamin D alters genes involved in follicular development and steroidogenesis in human cumulus granulosa cells. J Clin Endocrinol Metab 2014;99:E1137-45.
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E1137-E1145
    • Merhi, Z.1    Doswell, A.2    Krebs, K.3    Cipolla, M.4
  • 69
    • 84875630917 scopus 로고    scopus 로고
    • Supraphysiological leptin levels shift the profile of steroidogenesis in porcine ovarian follicles toward progesterone and testosterone secretion through increased expressions of cyp11a1 and 17b-h sd: A tissue culture approach
    • Gregoraszczuk E?, Rak-Mardya A. Supraphysiological leptin levels shift the profile of steroidogenesis in porcine ovarian follicles toward progesterone and testosterone secretion through increased expressions of CYP11A1 and 17b-H SD: a tissue culture approach. Reproduction 2013 145 311-7.
    • (2013) Reproduction , vol.145 , pp. 311-317
    • Gregoraszczuk, E.1    Rak-Mardya, A.2
  • 70
    • 84904670754 scopus 로고    scopus 로고
    • Putative role of adipose tissue in growth and metabolism of colon cancer cells
    • Schwartz B, Yehuda-Shnaidman E. Putative role of adipose tissue in growth and metabolism of colon cancer cells. Front Oncol 2014;4:164.
    • (2014) Front Oncol , vol.4 , pp. 164
    • Schwartz, B.1    Yehuda-Shnaidman, E.2
  • 72
    • 84872290190 scopus 로고    scopus 로고
    • Hypoxia and adipose tissue function and dysfunction in obesity
    • Trayhurn P. Hypoxia and adipose tissue function and dysfunction in obesity. Physiol Rev 2013;93:1-21.
    • (2013) Physiol Rev , vol.93 , pp. 1-21
    • Trayhurn, P.1
  • 73
    • 84893707651 scopus 로고    scopus 로고
    • Hypoxia, leptin, and vascular endothelial growth factor stim ulate vascular endothelial cell differentiation of human adipose tissue-derived stem cells
    • Bekhite MM, Finkensieper A, Rebhan J, Huse S, Schultze-Mosgau S, Figulla HR, Sauer H, Wartenberg M. Hypoxia, leptin, and vascular endothelial growth factor stim ulate vascular endothelial cell differentiation of human adipose tissue-derived stem cells. Stem Cells Dev 2014;23:333-51.
    • (2014) Stem Cells Dev , vol.23 , pp. 333-351
    • Bekhite, M.M.1    Finkensieper, A.2    Rebhan, J.3    Huse, S.4    Schultze-Mosgau, S.5    Figulla, H.R.6    Sauer, H.7    Wartenberg, M.8
  • 75
    • 84943198214 scopus 로고    scopus 로고
    • Visceral adipose tissue and t he risk of colorectal adenomas: A meta-Analysis of observational studies
    • Hu H, Cai Y, Huang J, Zhang J, Deng Y. Visceral adipose tissue and t he risk of colorectal adenomas: a meta-Analysis of observational studies. Eur J Cancer Prev 2014; doi: 10.1097/CEJ.0000000000000113.
    • (2014) Eur J Cancer Prev
    • Hu, H.1    Cai, Y.2    Huang, J.3    Zhang, J.4    Deng, Y.5
  • 76
    • 84884574047 scopus 로고    scopus 로고
    • Adipose tissued erived stem cells promote pancreatic cancer cell proliferation and invasion
    • Ji SQ, Cao J, Zhang QY, Li YY, Yan YQ, Yu FX. Adipose tissued erived stem cells promote pancreatic cancer cell proliferation and invasion. Braz J Med Biol Res 2013;46:758-64.
    • (2013) Braz J Med Biol Res , vol.46 , pp. 758-764
    • Ji, S.Q.1    Cao, J.2    Zhang, Q.Y.3    Li, Y.Y.4    Yan, Y.Q.5    Yu, F.X.6
  • 78
    • 84906271657 scopus 로고    scopus 로고
    • Effects of 12 weeks high dose Vitamin D3 treatment on insulin sensitivity, beta cell function, and metabolic markers in patients with type 2 diabetes and Vitamin D insufficiency-A double-blind, randomized, placebocontrolled trial
    • Kampmann U, Mosekilde L, Juhl C, Mol ler N, Christensen B, Rejnmark L, Wamberg L, Orskov L. Effects of 12 weeks high dose vitamin D3 treatment on insulin sensitivity, beta cell function, and metabolic markers in patients with type 2 diabetes and vitamin D insufficiency-A double-blind, randomized, placebocontrolled trial. Metabolism 2014;63:1115-24.
    • (2014) Metabolism , vol.63 , pp. 1115-1124
    • Kampmann, U.1    Mosekilde, L.2    Juhl, C.3    Moller, N.4    Christensen, B.5    Rejnmark, L.6    Wamberg, L.7    Orskov, L.8
  • 80
    • 84882338383 scopus 로고    scopus 로고
    • Evidences of dual role of Vitamin D through cellular energy homeostasis and inflammation pathway in risk of cancer in obese subjects
    • Hossein-Nezhad A, Mirzaei K, Keshavarz S A, Ansar H, Saboori S, Tootee A. Evidences of dual role of vitamin D through cellular energy homeostasis and inflammation pathway in risk of cancer in obese subjects. Minerva Med 2013;104:295-307.
    • (2013) Minerva Med , vol.104 , pp. 295-307
    • Hossein-Nezhad, A.1    Mirzaei, K.2    Keshavarz, S.A.3    Ansar, H.4    Saboori, S.5    Tootee, A.6
  • 81
    • 84929949038 scopus 로고    scopus 로고
    • Pathophysiological mechanisms linking obesity and esophageal adenocarcinoma
    • 1. Alexandre L, Long E, Beales IL. Pathophysiological mechanisms linking obesity and esophageal adenocarcinoma. World J Gastrointest Pathophysiol 2014;5:534-49.
    • (2014) World J Gastrointest Pathophysiol , vol.5 , pp. 534-549
    • Alexandre, L.1    Long, E.2    Beales, I.L.3
  • 82
    • 39649089581 scopus 로고    scopus 로고
    • Leptin and leptin receptor genotypes and colon cancer: Gene-gene and gene-lifestyle interactions
    • Slattery ML, Wolff RK, Herrick J, Caan BJ, Potter JD. Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. Int J Cancer 2008;122:1611-7.
    • (2008) Int J Cancer , vol.122 , pp. 1611-1617
    • Slattery, M.L.1    Wolff, R.K.2    Herrick, J.3    Caan, B.J.4    Potter, J.D.5
  • 83
    • 34347389223 scopus 로고    scopus 로고
    • Leptin in autoimmunity: Many questions, some answers
    • Matarese G, Leiter EH, La Cava A. Leptin in autoimmunity: many questions, some answers. Tissue Antigens 2007;70:87-95.
    • (2007) Tissue Antigens , vol.70 , pp. 87-95
    • Matarese, G.1    Leiter, E.H.2    La Cava, A.3
  • 87
    • 84879555168 scopus 로고    scopus 로고
    • Leptin stimulation of cell cycle and inhibition of apoptosis gene and protein expression in ovcar-3 ovarian cancer cells
    • Ptak A, Kolaczkowska E, Gregoraszczuk EL. Leptin stimulation of cell cycle and inhibition of apoptosis gene and protein expression in OVCAR-3 ovarian cancer cells. Endocrine 2013;43: 394-403 .
    • (2013) Endocrine , vol.43 , pp. 394-403
    • Ptak, A.1    Kolaczkowska, E.2    Gregoraszczuk, E.L.3
  • 88
    • 78650876692 scopus 로고    scopus 로고
    • Vitamin D evolutionary, physiological and health perspectives
    • Holick MF. Vitamin D: evolutionary, physiological and health perspectives. Curr Drug Targets 2011;12:4-18.
    • (2011) Curr Drug Targets , vol.12 , pp. 4-18
    • Holick, M.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.