1,25-Dyhydroxyvitamin D3 attenuates rotenone-induced neurotoxicity in SH-SY5Y cells through induction of autophagy

Biochemical and Biophysical Research Communications

Volumn 451, Issue 1, 2014, Pages 142-147

  Jang, Wooyoung ^a   Kim, Hee Ju ^b   Li, Huan ^b   Jo, Kwang Deog ^a   Lee, Moon Kyu ^a   Song, Sun Hong ^c   Yang, Hyun Ok ^b  

^a University of Ulsan College of Medicine   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c University of Ulsan   (South Korea)

Author keywords

Autophagy; Calcitriol; Neuroprotection; Parkinson's disease

Indexed keywords

BECLIN 1; CALCITRIOL; CASPASE 3; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; NEUROPROTECTIVE AGENT; PROTEIN BAK; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; ROTENONE; APOPTOSIS REGULATORY PROTEIN; BAK1 PROTEIN, HUMAN; BAX PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIGHT CHAIN 3, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; PROTECTIVE AGENT;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MTT ASSAY; NEUROPROTECTION; NEUROTOXICITY; PARKINSON DISEASE; PRIORITY JOURNAL; PROPIDIUM IODIDE ASSAY; WESTERN BLOTTING; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; NEUROTOXICITY SYNDROMES; PATHOLOGY; TOXICITY;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CALCITRIOL; CASPASE 3; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; NEUROTOXICITY SYNDROMES; PARKINSON DISEASE; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; ROTENONE;

EID: 84906217905     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.081     Document Type: Article

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