Adipose tissue-derived stem cells promote pancreatic cancer cell proliferation and invasion

Brazilian Journal of Medical and Biological Research

Volumn 46, Issue 9, 2013, Pages 758-764

  Ji, S Q ^b   Cao, J ^b   Zhang, Q Y ^a   Li, Y Y ^a   Yan, Y Q ^b   Yu, F X ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Adipose tissue derived stem cells; Invasion; Pancreatic cancer; Proliferation; SDF 1

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MESSENGER RNA; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1;

ADIPOSE DERIVED STEM CELL; ARTICLE; CELL DIFFERENTIATION; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; PANCREAS CANCER; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY;

ADIPOCYTES; ADIPOSE TISSUE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CHEMOKINE CXCL12; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CXCR4; RNA, MESSENGER; STEM CELLS;

EID: 84884574047     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/1414-431X20132907     Document Type: Article

References (33)

1. Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004; 432: 332-337, doi:10.1038/nature03096.
2. Armstrong T, Packham G, Murphy LB, Bateman AC, Conti JA, Fine DR, et al. Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma. Clin Cancer Res 2004; 10: 7427-7437, doi:10.1158/1078-0432.CCR-03-0825.
3. Bachem MG, Schunemann M, Ramadani M, Siech M, Beger H, Buck A, et al. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 2005; 128: 907-921, doi:10.1053/j.gastro.2004.12.036.
4. Miyamoto H, Murakami T, Tsuchida K, Sugino H, Miyake H, Tashiro S. Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and pro-iferation regulation is dependent on extracellular matrix proteins. Pancreas 2004; 28: 38-44, doi:10.1097/00006676200401000-00006.
5. Muerkoster S, Wegehenkel K, Arlt A, Witt M, Sipos B, Kruse ML, et al. Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res 2004; 64: 1331-1337, doi:10.1158/0008-5472.CAN-03-1860.
6. Ohuchida K, Mizumoto K, Murakami M, Qian LW, Sato N, Nagai E, et al. Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumorstromal interactions. Cancer Res 2004; 64: 3215-3222, doi:10.1158/0008-5472.CAN-03-2464.
7. Daly AJ, McIlreavey L, Irwin CR. Regulation of HGF and SDF-1 expression by oral fibroblasts implications for invasion of oral cancer. Oral Oncol 2008; 44: 646-651, doi:10.1016/j.oraloncology.2007.08.012.
8. Kajita T, Ohta Y, Kimura K, Tamura M, Tanaka Y, Tsunezuka Y, et al. The expression of vascular endothelial growth factor C and its receptors in non-small cell lung cancer. Br J Cancer 2001; 85: 255-260, doi:10.1054/bjoc.2001.1882.
9. Pablos JL, Amara A, Bouloc A, Santiago B, Caruz A, Galindo M, et al. Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin. Am J Pathol 1999; 155: 1577-1586, doi:10.1016/S0002-9440(10)65474-0.
10. Muehlberg FL, Song YH, Krohn A, Pinilla SP, Droll LH, Leng X, et al. Tissue-resident stem cells promote breast cancer growth and metastasis. Carcinogenesis 2009; 30: 589-597, doi:10.1093/carcin/bgp036.
11. Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, McCauley LK. Use of the stromal cell-derived factor-1/ CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 2002; 62: 1832-1837.
12. Schrader AJ, Lechner O, Templin M, Dittmar KE, Machtens S, Mengel M, et al. CXCR4/CXCL12 expression and signalling in kidney cancer. Br J Cancer 2002; 86: 1250-1256, doi:10.1038/sj.bjc.6600221.
13. Marchesi F, Monti P, Leone BE, Zerbi A, Vecchi A, Piemonti L, et al. Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4. Cancer Res 2004; 64: 8420-8427, doi:10.1158/0008-5472.CAN-04-1343.
14. Mori T.R, Koizumi M, Toyoda E, Ito D, Kami K, et al. CXCR4 antagonist inhibits stromal cell-derived factor 1 induced migration and invasion of human pancreatic cancer. Mol Cancer Ther 2004; 3: 29-37.
15. Wang J, Wang J, Sun Y, Song W, Nor JE, Wang CY, et al. Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis. Cell Signal 2005; 17: 1578-1592, doi:10.1016/j.cellsig.2005.03.022.
16. Kucerova L, Altanerova V, Matuskova M, Tyciakova S, Altaner C. Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. Cancer Res 2007; 67: 6304-6313, doi:10.1158/0008-5472.CAN-06-4024.
17. Prantl L, Muehlberg F, Navone NM, Song YH, Vykoukal J, Logothetis CJ, et al. Adipose tissue-derived stem cells promote prostate tumor growth. Prostate 2010; 70: 1709-1715, doi:10.1002/pros.21206.
18. Yu JM, Jun ES, Bae YC, Jung JS. Mesenchymal stem cells derived from human adipose tissues favor tumor cell growth in vivo. Stem Cells Dev 2008; 17: 463-473, doi:10.1089/scd.2007.0181.
19. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, et al. Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med 2006; 203: 1235-1247, doi:10.1084/jem.20051921.
20. Qiao L, Xu ZL, Zhao TJ, Ye LH, Zhang XD. Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling. Cancer Lett 2008; 269: 67-77, doi:10.1016/j.canlet.2008.04.032.
21. de Wever O, Mareel M. Role of tissue stroma in cancer cell invasion. J Pathol 2003; 200: 429-447, doi:10.1002/path.1398.
22. Liotta LA, Kohn EC. The microenvironment of the tumourhost interface. Nature 2001; 411: 375-379, doi:10.1038/ 35077241.
23. Burger JA, Kipps TJ. CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006; 107: 1761-1767, doi:10.1182/blood-2005-08-3182.
24. Balkwill F. Cancer and the chemokine network. Nat Rev Cancer 2004; 4: 540-550, doi:10.1038/nrc1388.
25. Homey B, Muller A, Zlotnik A. Chemokines: agents for the immunotherapy of cancer? Nat Rev Immunol 2002; 2: 175-184, doi:10.1038/nri748.
26. Murphy PM. Chemokines and the molecular basis of cancer metastasis. N Engl J Med 2001; 345: 833-835, doi:10.1056/ NEJM200109133451113.
27. Brand S, Dambacher J, Beigel F, Olszak T, Diebold J, Otte JM, et al. CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. Exp Cell Res 2005; 310: 117-130, doi:10.1016/j.yexcr.2005.07.006.
28. Koshiba T, Hosotani R, Miyamoto Y, Ida J, Tsuji S, Nakajima S, et al. Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression. Clin Cancer Res 2000; 6: 3530-3535.
29. Billadeau DD, Chatterjee S, Bramati P, Sreekumar R, Shah V, Hedin K, et al. Characterization of the CXCR4 signaling in pancreatic cancer cells. Int J Gastrointest Cancer 2006; 37: 110-119.
30. Nagakawa Y, Aoki T, Kasuya K, Tsuchida A, Koyanagi Y. Histologic features of venous invasion, expression of vascular endothelial growth factor and matrix metalloproteinase-2 and matrix metalloproteinase-9, and the relation with liver metastasis in pancreatic cancer. Pancreas 2002; 24: 169-178, doi:10.1097/00006676-200203000-00008.
31. Iyengar P, Combs TP, Shah SJ, Gouon-Evans V, Pollard JW, Albanese C, et al. Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and protooncogene stabilization. Oncogene 2003; 22: 6408-6423, doi:10.1038/sj.onc.1206737.
32. Matsuo Y, Ochi N, Sawai H, Yasuda A, Takahashi H, Funahashi H, et al. CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer. Int J Cancer 2009; 124: 853-861, doi:10.1002/ijc.24040
33. Niedergethmann M, Alves F, Neff JK, Heidrich B, Aramin N, Li L, et al. Gene expression profiling of liver metastases and tumour invasion in pancreatic cancer using an orthotopic SCID mouse model. Br J Cancer 2007; 97: 1432-1440, doi:10.1038/sj.bjc.6604031.