Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration

Protein and Cell

Volumn 7, Issue 6, 2016, Pages 391-402

  Feng, Juan ^a   Lü, Silin ^a   Ding, Yanhong ^a   Zheng, Ming ^a   Wang, Xian ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

endoplasmic reticulum stress; homocysteine; mitochondria; T cell

Indexed keywords

GAMMA INTERFERON; HOMOCYSTEINE; REACTIVE OXYGEN METABOLITE; 4-PHENYLBUTYRIC ACID; ARYLBUTYRIC ACID DERIVATIVE; CALCIUM; ERN1 PROTEIN, MOUSE; NOCODAZOLE; PERK KINASE; PROTEIN KINASE B; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM SIGNALING; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM MITOCHONDRIA COUPLING; ENDOPLASMIC RETICULUM STRESS; FEMALE; FLOW CYTOMETRY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE COUPLING; OXYGEN CONSUMPTION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; METABOLIC ENGINEERING; METABOLISM; MITOCHONDRION; T LYMPHOCYTE;

ANIMALS; CALCIUM; CELL PROLIFERATION; CELLS, CULTURED; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FEMALE; HOMOCYSTEINE; INTERFERON-GAMMA; METABOLIC ENGINEERING; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NOCODAZOLE; PHENYLBUTYRATES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; T-LYMPHOCYTES;

EID: 84957684736     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-016-0245-x     Document Type: Article

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