Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans

Diabetologia

Volumn 59, Issue 5, 2016, Pages 1040-1048

  Gemmink, Anne ^a   Bosma, Madeleen ^a,b   Kuijpers, Helma J H ^c   Hoeks, Joris ^a   Schaart, Gert ^a   van Zandvoort, Marc A M J ^c,d   Schrauwen, Patrick ^a   Hesselink, Matthijs K C ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KAROLINSKA INSTITUTE   (Sweden)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Fasting; IMCL; Lipid droplet size; Lipotoxicity; Perilipin 5

Indexed keywords

COENZYME A; FAT DROPLET; GLUTAMIC ACID; LAMININ; PERILIPIN; PERILIPIN 5; SUCCINIC ACID; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAMYOCELLULAR LIPID CONTENT; LIPID STORAGE; LIPOTOXICITY; MALE; MORPHOMETRICS; MUSCLE BIOPSY; PRIORITY JOURNAL; PROTEIN CONTENT; CONTROLLED STUDY; DIET RESTRICTION; METABOLISM; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; YOUNG ADULT;

ADULT; BLOTTING, WESTERN; FASTING; HUMANS; INSULIN RESISTANCE; LAMININ; LIPID DROPLETS; MALE; PERILIPIN-5; REAL-TIME POLYMERASE CHAIN REACTION; YOUNG ADULT;

EID: 84957640093     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-016-3865-z     Document Type: Article

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