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Volumn 90, Issue 5, 2012, Pages 411-419

17β-estradiol rapidly activates calcium release from intracellular stores via the GPR30 pathway and MAPK phosphorylation in osteocyte-like MLO-Y4 cells

Author keywords

Calcium ion; Estrogen; Estrogen receptor; GPR30; MAPK; Osteocyte

Indexed keywords

CALCIUM ION; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; G PROTEIN COUPLED RECEPTOR 30; MITOGEN ACTIVATED PROTEIN KINASE;

EID: 84862781225     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-012-9581-x     Document Type: Article
Times cited : (24)

References (34)
  • 1
    • 78651395974 scopus 로고    scopus 로고
    • Preventing osteoporosis in symptomatic postmenopausal women
    • 20661164 10.1097/gme.0b013e3181e324a6
    • JC Gallagher JP Levine 2011 Preventing osteoporosis in symptomatic postmenopausal women Menopause 18 1 109 118 20661164 10.1097/gme. 0b013e3181e324a6
    • (2011) Menopause , vol.18 , Issue.1 , pp. 109-118
    • Gallagher, J.C.1    Levine, J.P.2
  • 2
    • 77649193010 scopus 로고    scopus 로고
    • Osteocyte apoptosis and control of bone resorption following ovariectomy in mice
    • 19925896 10.1016/j.bone.2009.11.006 1:CAS:528:DC%2BC3cXitV2htLk%3D
    • KB Emerton B Hu AA Woo, et al. 2010 Osteocyte apoptosis and control of bone resorption following ovariectomy in mice Bone 46 43 577 583 19925896 10.1016/j.bone.2009.11.006 1:CAS:528:DC%2BC3cXitV2htLk%3D
    • (2010) Bone , vol.46 , Issue.43 , pp. 577-583
    • Emerton, K.B.1    Hu, B.2    Woo, A.A.3
  • 3
    • 43549095238 scopus 로고    scopus 로고
    • Estrogen signaling through the transmembrane G protein-coupled receptor GPR30
    • DOI 10.1146/annurev.physiol.70.113006.100518
    • ER Prossnitz BA Jeffrey OS Harriet 2008 Estrogen signaling through the transmembrane G protein-coupled receptor GPR30 Annu Rev Physiol 70 165 190 18271749 10.1146/annurev.physiol.70.113006.100518 1:CAS:528:DC%2BD1cXkt1eqtrw%3D (Pubitemid 351738176)
    • (2008) Annual Review of Physiology , vol.70 , pp. 165-190
    • Prossnitz, E.R.1    Arterburn, J.B.2    Smith, H.O.3    Oprea, T.I.4    Sklar, L.A.5    Hathaway, H.J.6
  • 4
    • 24044441632 scopus 로고    scopus 로고
    • 2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: A potential initiation mechanism for estrogen-induced neuroprotection
    • DOI 10.1016/j.neuroscience.2004.12.027, PII S0306452205000333
    • 2+ influx via L-type calcium channel activates the SRC/ERK/c-AMP response element binding protein signal pathway and BCL-2 expression in rat hippocampal neurons: a potential initiation mechanism for estrogen-induced neuroprotection Neuroscience 135 159 172 10.1016/j.neuroscience.2004.12.027 (Pubitemid 41219738)
    • (2005) Neuroscience , vol.135 , Issue.1 , pp. 59-72
    • Wu, T.-W.1    Wang, J.M.2    Chen, S.3    Brinton, R.D.4
  • 5
    • 77957345404 scopus 로고    scopus 로고
    • Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes
    • 20881113 10.1523/JNEUROSCI.1158-10.2010 1:CAS:528:DC%2BC3cXht1KisLvL
    • J Kuo N Hamid G Bondar ER Prossnitz P Micevych 2010 Membrane estrogen receptors stimulate intracellular calcium release and progesterone synthesis in hypothalamic astrocytes J Neurosci 30 39 12950 12957 20881113 10.1523/JNEUROSCI.1158-10.2010 1:CAS:528:DC%2BC3cXht1KisLvL
    • (2010) J Neurosci , vol.30 , Issue.39 , pp. 12950-12957
    • Kuo, J.1    Hamid, N.2    Bondar, G.3    Prossnitz, E.R.4    Micevych, P.5
  • 6
    • 49549099539 scopus 로고    scopus 로고
    • 17β-Estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKA-Erk-dependent pathway in the human eccrine sweat gland cell line NCL-SG3
    • 18215419 10.1016/j.ceca.2007.12.001 1:CAS:528:DC%2BD1cXhtVejs7zF
    • RW Muchekehu JH Brain 2008 17β-Estradiol rapidly mobilizes intracellular calcium from ryanodine-receptor-gated stores via a PKC-PKA-Erk-dependent pathway in the human eccrine sweat gland cell line NCL-SG3 Cell Calcium 44 276 288 18215419 10.1016/j.ceca.2007.12.001 1:CAS:528:DC%2BD1cXhtVejs7zF
    • (2008) Cell Calcium , vol.44 , pp. 276-288
    • Muchekehu, R.W.1    Brain, J.H.2
  • 7
    • 77649273816 scopus 로고    scopus 로고
    • An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation
    • 20060586 10.1016/j.ceca.2009.12.005 1:CAS:528:DC%2BC3cXjt1KgsLg%3D
    • B Huo XL Lu KD Costa, et al. 2010 An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation Cell Calcium 47 43 234 241 20060586 10.1016/j.ceca.2009.12.005 1:CAS:528:DC%2BC3cXjt1KgsLg%3D
    • (2010) Cell Calcium , vol.47 , Issue.43 , pp. 234-241
    • Huo, B.1    Lu, X.L.2    Costa, K.D.3
  • 8
    • 75149186664 scopus 로고    scopus 로고
    • The unfolding stories of GPR30, a new membrane-bound estrogen receptor
    • 10.1677/JOE-09-0242
    • M Marcello P Didier 2010 The unfolding stories of GPR30, a new membrane-bound estrogen receptor J Endocrinol 204 105 114 10.1677/JOE-09-0242
    • (2010) J Endocrinol , vol.204 , pp. 105-114
    • Marcello, M.1    Didier, P.2
  • 9
    • 67349105361 scopus 로고    scopus 로고
    • Mechanisms of estrogen signaling and gene expression via GPR30
    • 19464786 10.1016/j.mce.2009.03.026 1:CAS:528:DC%2BD1MXnsFant7s%3D
    • ER Prossnitz M Maggiolini 2009 Mechanisms of estrogen signaling and gene expression via GPR30 Mol Cell Endocrinol 308 1-2 32 38 19464786 10.1016/j.mce.2009.03.026 1:CAS:528:DC%2BD1MXnsFant7s%3D
    • (2009) Mol Cell Endocrinol , vol.308 , Issue.12 , pp. 32-38
    • Prossnitz, E.R.1    Maggiolini, M.2
  • 10
    • 79952317334 scopus 로고    scopus 로고
    • Membrane estrogen receptors mediate calcium signaling and MAP kinase activation in individual hippocampal neurons
    • 10.1016/j.brainres.2011.01.034
    • TW Wu S Chen RD Brinton 2011 Membrane estrogen receptors mediate calcium signaling and MAP kinase activation in individual hippocampal neurons Brain Res 1379 1334 1343 10.1016/j.brainres.2011.01.034
    • (2011) Brain Res , vol.1379 , pp. 1334-1343
    • Wu, T.W.1    Chen, S.2    Brinton, R.D.3
  • 11
    • 33847755409 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • DOI 10.1158/0008-5472.CAN-06-2909
    • L Albanito A Madeo R Lappano, et al. 2007 G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells Cancer Res 67 4 1859 1866 17308128 10.1158/0008-5472.CAN-06-2909 1:CAS:528:DC%2BD2sXhvVajs78%3D (Pubitemid 46383413)
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3    Vivacqua, A.4    Rago, V.5    Carpino, A.6    Oprea, T.I.7    Prossnitz, E.R.8    Musti, A.M.9    Ando, S.10    Maggiolini, M.11
  • 12
    • 34247895595 scopus 로고    scopus 로고
    • G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage
    • DOI 10.2353/ajpath.2007.060883
    • YC Hsieh HP Yu M Frink, et al. 2007 G protein-coupled receptor 30-dependent protein kinase A pathway is critical in non-genomic effects of estrogen in attenuating liver injury after trauma-hemorrhage Am J Pathol 170 4 1210 1218 17392161 10.2353/ajpath.2007.060883 1:CAS:528:DC%2BD2sXkvFymsLY%3D (Pubitemid 47339329)
    • (2007) American Journal of Pathology , vol.170 , Issue.4 , pp. 1210-1218
    • Hsieh, Y.-C.1    Yu, H.-P.2    Frink, M.3    Suzuki, T.4    Choudhry, M.A.5    Schwacha, M.G.6    Chaudry, I.H.7
  • 13
    • 33846813959 scopus 로고    scopus 로고
    • The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro
    • DOI 10.1016/j.bone.2006.10.014, PII S8756328206007927
    • V Mann C Huber G Kogianni, et al. 2007 The antioxidant effect of estrogen and selective estrogen receptor modulators in the inhibition of osteocyte apoptosis in vitro Bone 40 43 674 684 17174166 10.1016/j.bone.2006.10.014 1:CAS:528:DC%2BD2sXhtlSks7k%3D (Pubitemid 46201947)
    • (2007) Bone , vol.40 , Issue.3 , pp. 674-684
    • Mann, V.1    Huber, C.2    Kogianni, G.3    Collins, F.4    Noble, B.5
  • 14
    • 43849105081 scopus 로고    scopus 로고
    • The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone
    • DOI 10.1677/JOE-07-0629
    • TJ Heino AS Chagin L Sävendahl 2008 The novel estrogen receptor G-protein-coupled receptor 30 is expressed in human bone J Endocrinol 197 2 R1 R6 18434348 10.1677/JOE-07-0629 1:CAS:528:DC%2BD1cXmsVOltb0%3D (Pubitemid 351696258)
    • (2008) Journal of Endocrinology , vol.197 , Issue.2
    • Heino, T.J.1    Chagin, A.S.2    Savendahl, L.3
  • 15
    • 23044495913 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent kinases in skeletal muscle plasticity
    • DOI 10.1152/japplphysiol.00015.2005
    • 2+/calmodulin-dependent kinases in skeletal muscle plasticity J Appl Physiol 99 2 414 423 16020436 10.1152/japplphysiol.00015.2005 1:CAS:528:DC%2BD2MXpsVaqsr0%3D (Pubitemid 41061133)
    • (2005) Journal of Applied Physiology , vol.99 , Issue.2 , pp. 414-423
    • Chin, E.R.1
  • 16
    • 14944361741 scopus 로고    scopus 로고
    • A new mediator for an old hormone?
    • DOI 10.1126/science.1110345
    • SC Hewitt BJ Deroo KS Korach 2005 A new mediator for an old hormone? Science 307 5715 1572 1573 15761144 10.1126/science.1110345 1:CAS:528: DC%2BD2MXitlarurc%3D (Pubitemid 40354728)
    • (2005) Science , vol.307 , Issue.5715 , pp. 1572-1573
    • Hewitt, S.C.1    Deroo, B.J.2    Korach, K.S.3
  • 18
    • 33646366423 scopus 로고    scopus 로고
    • Virtual and biomolecular screening converge on a selective agonist for GPR30
    • 16520733 10.1038/nchembio775 1:CAS:528:DC%2BD28XisFOnsbs%3D
    • CG Bologa CM Revankar SM Young, et al. 2006 Virtual and biomolecular screening converge on a selective agonist for GPR30 Nat Chem Biol 2 4 207 212 16520733 10.1038/nchembio775 1:CAS:528:DC%2BD28XisFOnsbs%3D
    • (2006) Nat Chem Biol , vol.2 , Issue.4 , pp. 207-212
    • Bologa, C.G.1    Revankar, C.M.2    Young, S.M.3
  • 19
    • 67349140294 scopus 로고    scopus 로고
    • In vivo effects of a GPR30 antagonist
    • 19430488 10.1038/nchembio.168 1:CAS:528:DC%2BD1MXls1Cmtr0%3D
    • MK Dennis R Burai C Ramesh, et al. 2009 In vivo effects of a GPR30 antagonist Nat Chem Biol 5 6 421 427 19430488 10.1038/nchembio.168 1:CAS:528:DC%2BD1MXls1Cmtr0%3D
    • (2009) Nat Chem Biol , vol.5 , Issue.6 , pp. 421-427
    • Dennis, M.K.1    Burai, R.2    Ramesh, C.3
  • 20
    • 33645221301 scopus 로고    scopus 로고
    • The predominant mechanism of intercellular calcium wave propagation changes during long-term culture of human osteoblast-like cells
    • 16545868 10.1016/j.ceca.2006.01.012 1:CAS:528:DC%2BD28XjtFOktr8%3D
    • Z Henriksen JF Hiken TH Steinberg NR Jørgensen 2006 The predominant mechanism of intercellular calcium wave propagation changes during long-term culture of human osteoblast-like cells Cell Calcium 39 35 435 444 16545868 10.1016/j.ceca.2006.01.012 1:CAS:528:DC%2BD28XjtFOktr8%3D
    • (2006) Cell Calcium , vol.39 , Issue.35 , pp. 435-444
    • Henriksen, Z.1    Hiken, J.F.2    Steinberg, T.H.3    Jørgensen, N.R.4
  • 22
    • 38149120809 scopus 로고    scopus 로고
    • 17β-Estradiol induces the translocation of the estrogen receptors ESR1 and ESR2 to the cell membrane, MAPK3/1 phosphorylation and proliferation of cultured immature rat sertoli cells
    • 17928626 10.1095/biolreprod.107.063909 1:CAS:528:DC%2BD1cXlslM%3D
    • TF Lucas ER Siu CA Esteves, et al. 2008 17β-Estradiol induces the translocation of the estrogen receptors ESR1 and ESR2 to the cell membrane, MAPK3/1 phosphorylation and proliferation of cultured immature rat sertoli cells Biol Reprod 78 71 101 114 17928626 10.1095/biolreprod.107.063909 1:CAS:528:DC%2BD1cXlslM%3D
    • (2008) Biol Reprod , vol.78 , Issue.71 , pp. 101-114
    • Lucas, T.F.1    Siu, E.R.2    Esteves, C.A.3
  • 23
    • 79956308108 scopus 로고    scopus 로고
    • G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium
    • 21427217 10.1210/en.2010-0979 1:CAS:528:DC%2BC3MXns1Sntb8%3D
    • K Maiti J Paul M Read, et al. 2011 G-1-activated membrane estrogen receptors mediate increased contractility of the human myometrium Endocrinology 152 6 2448 2455 21427217 10.1210/en.2010-0979 1:CAS:528:DC%2BC3MXns1Sntb8%3D
    • (2011) Endocrinology , vol.152 , Issue.6 , pp. 2448-2455
    • Maiti, K.1    Paul, J.2    Read, M.3
  • 24
    • 44549086936 scopus 로고    scopus 로고
    • MNAR plays an important role in ERa activation of Src/MAPK and PI3 K/Akt signaling pathways
    • 18261753 10.1016/j.steroids.2007.12.028 1:CAS:528:DC%2BD1cXmvFensb8%3D
    • BJ Cheskis J Greger N Cooch, et al. 2008 MNAR plays an important role in ERa activation of Src/MAPK and PI3 K/Akt signaling pathways Steroids 73 79-10 901 905 18261753 10.1016/j.steroids.2007.12.028 1:CAS:528:DC%2BD1cXmvFensb8%3D
    • (2008) Steroids , vol.73 , Issue.7910 , pp. 901-905
    • Cheskis, B.J.1    Greger, J.2    Cooch, N.3
  • 26
    • 63749118192 scopus 로고    scopus 로고
    • Rapid action of oestrogen in luteinising hormone-releasing hormone neurones: The role of GPR30
    • 19207808 10.1111/j.1365-2826.2009.01839.x 1:CAS:528:DC%2BD1MXks1Wnurc%3D
    • E Terasawa S Noel KL Keen 2009 Rapid action of oestrogen in luteinising hormone-releasing hormone neurones: the role of GPR30 J Neuroendocrinol 21 24 316 321 19207808 10.1111/j.1365-2826.2009.01839.x 1:CAS:528:DC%2BD1MXks1Wnurc%3D
    • (2009) J Neuroendocrinol , vol.21 , Issue.24 , pp. 316-321
    • Terasawa, E.1    Noel, S.2    Keen, K.L.3
  • 27
    • 77955918599 scopus 로고    scopus 로고
    • Estrogen receptor α and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models
    • S Gingerich GL Kim JA Chalmers, et al. 2010 Estrogen receptor α and G-protein coupled receptor 30 mediate the neuroprotective effects of 17β-estradiol in novel murine hippocampal cell models Neuroscience 170 171 154 166
    • (2010) Neuroscience , vol.170 , Issue.171 , pp. 154-166
    • Gingerich, S.1    Kim, G.L.2    Chalmers, J.A.3
  • 28
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • DOI 10.1016/j.cell.2007.11.028, PII S0092867407015310
    • DE Clapham 2007 Calcium signaling Cell 131 136 1047 1058 18083096 10.1016/j.cell.2007.11.028 1:CAS:528:DC%2BD1cXksFGgsA%3D%3D (Pubitemid 350258556)
    • (2007) Cell , vol.131 , Issue.6 , pp. 1047-1058
    • Clapham, D.E.1
  • 29
    • 0034997845 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
    • DOI 10.1210/er.22.2.153
    • G Pearson F Robinson BT Gibson, et al. 2001 Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions Endocr Rev 22 2 153 183 11294822 10.1210/er.22.2.153 1:CAS:528:DC%2BD3MXjsFSntL4%3D (Pubitemid 32458157)
    • (2001) Endocrine Reviews , vol.22 , Issue.2 , pp. 153-183
    • Pearson, G.1    Robinson, F.2    Gibson, T.B.3    Xu, B.-E.4    Karandikar, M.5    Berman, K.6    Cobb, M.H.7
  • 30
    • 80052006781 scopus 로고    scopus 로고
    • 1 subunit with Ca(v)3.2 enhances membrane expression and regulates mechanically induced ATP release in MLO-Y4 osteocytes
    • 21638318 10.1002/jbmr.437 1:CAS:528:DC%2BC3MXht1CjsrnL
    • 1 subunit with Ca(v)3.2 enhances membrane expression and regulates mechanically induced ATP release in MLO-Y4 osteocytes J Bone Miner Res 26 9 2125 2139 21638318 10.1002/jbmr.437 1:CAS:528: DC%2BC3MXht1CjsrnL
    • (2011) J Bone Miner Res , vol.26 , Issue.9 , pp. 2125-2139
    • Thompson, W.R.1    Majid, A.S.2    Czymmek, K.J.3
  • 31
    • 77950633401 scopus 로고    scopus 로고
    • New strategies in estrogen receptor-positive breast cancer
    • 20332324 10.1158/1078-0432.CCR-09-1823 1:CAS:528:DC%2BC3cXktFygu7o%3D
    • SR Johnston 2010 New strategies in estrogen receptor-positive breast cancer Clin Cancer Res 16 7 1979 1987 20332324 10.1158/1078-0432.CCR-09-1823 1:CAS:528:DC%2BC3cXktFygu7o%3D
    • (2010) Clin Cancer Res , vol.16 , Issue.7 , pp. 1979-1987
    • Johnston, S.R.1
  • 32
    • 77149180777 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in triple-negative and basal-like breast cancer: Promising clinical target or only a marker?
    • 20164687 10.1097/PPO.0b013e3181d24fc1 1:CAS:528:DC%2BC3cXjvVKkt7Y%3D
    • ML Burness TA Grushko OI Olopade 2010 Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker? Cancer J 16 1 23 32 20164687 10.1097/PPO.0b013e3181d24fc1 1:CAS:528:DC%2BC3cXjvVKkt7Y%3D
    • (2010) Cancer J , vol.16 , Issue.1 , pp. 23-32
    • Burness, M.L.1    Grushko, T.A.2    Olopade, O.I.3
  • 34
    • 0033055990 scopus 로고    scopus 로고
    • Establishment and characterization of an osteocyte-like cell line, MLO- Y4
    • DOI 10.1007/s007740050066
    • LF Bonewald 1999 Establishment and characterization of an osteocyte-like cell line, MLO-Y4 J Bone Miner Metab 17 1 61 65 10084404 10.1007/s007740050066 1:STN:280:DyaK1M7otFyqtw%3D%3D (Pubitemid 29117755)
    • (1999) Journal of Bone and Mineral Metabolism , vol.17 , Issue.1 , pp. 61-65
    • Bonewald, L.F.1


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