Dehydroepiandrosterone activation of G-protein-coupled estrogen receptor rapidly stimulates MicroRNA-21 transcription in human hepatocellular carcinoma cells

Journal of Biological Chemistry

Volumn 290, Issue 25, 2015, Pages 15799-15811

  Teng, Yun ^a   Radde, Brandie N ^a   Litchfield, Lacey M ^a   Ivanova, Margarita M ^a   Prough, Russell A ^a   Clark, Barbara J ^a   Doll, Mark A ^a   Hein, David W ^a   Klinge, Carolyn M ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; GENE EXPRESSION; PROTEINS;

DEHYDROEPIANDROSTERONE; EPIDERMAL GROWTH FACTOR RECEPTORS; G PROTEIN COUPLED RECEPTORS; HEPATOCELLULAR CARCINOMA CELL; INTRACELLULAR SIGNALING; PHYSIOLOGICAL CONCENTRATIONS; PRIMARY HUMAN HEPATOCYTES; PROTEIN EXPRESSIONS;

TRANSCRIPTION;

EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR ALPHA 36; G PROTEIN COUPLED RECEPTOR 30; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PRASTERONE; PROTEIN C FOS; PROTEIN C JUN; PROTEIN KINASE P60; UNCLASSIFIED DRUG; ANDROGEN RECEPTOR; CSK TYROSINE-PROTEIN KINASE; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA, HUMAN; G PROTEIN COUPLED RECEPTOR; GPER PROTEIN, HUMAN; IMMUNOLOGICAL ADJUVANT; MAPK1 PROTEIN, HUMAN; MICRORNA; MIRN21 MICRORNA, HUMAN; PROTEIN TYROSINE KINASE; RNA; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIVER CELL CARCINOMA; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN RNA BINDING; PROTEIN SECRETION; PROTEIN SYNTHESIS; RNA INTERFERENCE; RNA TRANSCRIPTION; SEX DIFFERENCE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION; BIOSYNTHESIS; DNA RESPONSIVE ELEMENT; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HEPG2 CELL LINE; LIVER TUMOR; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ADJUVANTS, IMMUNOLOGIC; CARCINOMA, HEPATOCELLULAR; DEHYDROEPIANDROSTERONE; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MAP KINASE SIGNALING SYSTEM; MICRORNAS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED; RESPONSE ELEMENTS; RNA, NEOPLASM; SRC-FAMILY KINASES; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC;

EID: 84938839072     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.641167     Document Type: Article

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