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Volumn 84, Issue 1, 2015, Pages 339-350

Toxoplasma gondii GRA7-induced TRAF6 activation contributes to host protective immunity

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MYELOID DIFFERENTIATION FACTOR 88; REACTIVE OXYGEN METABOLITE; RECOMBINANT GRANULE ANTIGEN 7 PROTEIN; RECOMBINANT PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; CYBB PROTEIN, MOUSE; GRA7 PROTEIN, TOXOPLASMA GONDII; MEMBRANE PROTEIN; MYD88 PROTEIN, MOUSE; NEUTROPHIL CYTOSOLIC FACTOR 1; PARASITE ANTIGEN; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

EID: 84957611936     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00734-15     Document Type: Article
Times cited : (35)

References (50)
  • 1
    • 84892910206 scopus 로고    scopus 로고
    • Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse
    • Alaganan A, Fentress SJ, Tang K, Wang Q, Sibley LD. 2014. Toxoplasma GRA7 effector increases turnover of immunity-related GTPases and contributes to acute virulence in the mouse. Proc Natl Acad Sci U S A 111: 1126-1131. http://dx.doi.org/10.1073/pnas.1313501111.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 1126-1131
    • Alaganan, A.1    Fentress, S.J.2    Tang, K.3    Wang, Q.4    Sibley, L.D.5
  • 2
    • 33646469572 scopus 로고    scopus 로고
    • Potent antigenspecific immunity to Toxoplasma gondii in adjuvant-free vaccination system using Rop2-Leishmania infantum Hsp83 fusion protein
    • Echeverria PC, de Miguel N, Costas M, Angel SO. 2006. Potent antigenspecific immunity to Toxoplasma gondii in adjuvant-free vaccination system using Rop2-Leishmania infantum Hsp83 fusion protein. Vaccine 24: 4102-4110. http://dx.doi.org/10.1016/j.vaccine.2006.02.039.
    • (2006) Vaccine , vol.24 , pp. 4102-4110
    • Echeverria, P.C.1    de Miguel, N.2    Costas, M.3    Angel, S.O.4
  • 4
    • 84864766099 scopus 로고    scopus 로고
    • Enhancement of protective immune responses induced by Toxoplasma gondii dense granule antigen 7 (GRA7) against toxoplasmosis in mice using a prime-boost vaccination strategy
    • Min J, Qu D, Li C, Song X, Zhao Q, Li XA, Yang Y, Liu Q, He S, Zhou H. 2012. Enhancement of protective immune responses induced by Toxoplasma gondii dense granule antigen 7 (GRA7) against toxoplasmosis in mice using a prime-boost vaccination strategy. Vaccine 30:5631-5636. http://dx.doi.org/10.1016/j.vaccine.2012.06.081.
    • (2012) Vaccine , vol.30 , pp. 5631-5636
    • Min, J.1    Qu, D.2    Li, C.3    Song, X.4    Zhao, Q.5    Li, X.A.6    Yang, Y.7    Liu, Q.8    He, S.9    Zhou, H.10
  • 5
    • 1542345731 scopus 로고    scopus 로고
    • The SRS superfamily of Toxoplasma surface proteins
    • Jung C, Lee CY, Grigg ME. 2004. The SRS superfamily of Toxoplasma surface proteins. Int J Parasitol 34:285-296. http://dx.doi.org/10.1016/j.ijpara.2003.12.004.
    • (2004) Int J Parasitol , vol.34 , pp. 285-296
    • Jung, C.1    Lee, C.Y.2    Grigg, M.E.3
  • 6
    • 84860321117 scopus 로고    scopus 로고
    • Induction of protective immune responses by a multiantigenic DNA vaccine encoding GRA7 and ROP1 of Toxoplasma gondii
    • Quan JH, Chu JQ, Ismail HA, Zhou W, Jo EK, Cha GH, Lee YH. 2012. Induction of protective immune responses by a multiantigenic DNA vaccine encoding GRA7 and ROP1 of Toxoplasma gondii. Clin Vaccine Immunol 19:666-674. http://dx.doi.org/10.1128/CVI.05385-11.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 666-674
    • Quan, J.H.1    Chu, J.Q.2    Ismail, H.A.3    Zhou, W.4    Jo, E.K.5    Cha, G.H.6    Lee, Y.H.7
  • 8
    • 84893115383 scopus 로고    scopus 로고
    • Innate immunity to Toxoplasma gondii infection
    • Yarovinsky F. 2014. Innate immunity to Toxoplasma gondii infection. Nat Rev Immunol 14:109-121. http://dx.doi.org/10.1038/nri3598.
    • (2014) Nat Rev Immunol , vol.14 , pp. 109-121
    • Yarovinsky, F.1
  • 13
    • 23344436402 scopus 로고    scopus 로고
    • Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70
    • Mun HS, Aosai F, Norose K, Piao LX, Fang H, Akira S, Yano A. 2005. Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70. Infect Immun 73:4634-4642 http://dx.doi.org/10.1128/IAI.73.8.4634-4642.2005.
    • (2005) Infect Immun , vol.73 , pp. 4634-4642
    • Mun, H.S.1    Aosai, F.2    Norose, K.3    Piao, L.X.4    Fang, H.5    Akira, S.6    Yano, A.7
  • 14
  • 15
    • 40249088259 scopus 로고    scopus 로고
    • The DNA sugar backbone 2' deoxyribose determines Toll-like receptor 9 activation
    • Haas T, Metzger J, Schmitz F, Heit A, Müller T, Latz E, Wagner H. 2008 The DNA sugar backbone 2' deoxyribose determines Toll-like receptor 9 activation. Immunity 28:315-323. http://dx.doi.org/10.1016/j.immuni.2008.01.013.
    • (2008) Immunity , vol.28 , pp. 315-323
    • Haas, T.1    Metzger, J.2    Schmitz, F.3    Heit, A.4    Müller, T.5    Latz, E.6    Wagner, H.7
  • 16
    • 0037097795 scopus 로고    scopus 로고
    • Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells
    • Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A. 2002. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J Immunol 168:5997-6001. http://dx.doi.org/10.4049/jimmunol.168.12.5997.
    • (2002) J Immunol , vol.168 , pp. 5997-6001
    • Scanga, C.A.1    Aliberti, J.2    Jankovic, D.3    Tilloy, F.4    Bennouna, S.5    Denkers, E.Y.6    Medzhitov, R.7    Sher, A.8
  • 17
    • 77953714711 scopus 로고    scopus 로고
    • Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling
    • Lin SC, Lo YC, Wu H. 2010. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature 465:885-890. http://dx.doi.org/10.1038/nature09121.
    • (2010) Nature , vol.465 , pp. 885-890
    • Lin, S.C.1    Lo, Y.C.2    Wu, H.3
  • 18
    • 4644244927 scopus 로고    scopus 로고
    • TRAF6-dependent mitogen-activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii
    • Mason NJ, Fiore J, Kobayashi T, Masek KS, Choi Y, Hunter CA. 2004. TRAF6-dependent mitogen-activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii. Infect Immun 72:5662-5667. http://dx.doi.org/10.1128/IAI.72.10.5662-5667.2004.
    • (2004) Infect Immun , vol.72 , pp. 5662-5667
    • Mason, N.J.1    Fiore, J.2    Kobayashi, T.3    Masek, K.S.4    Choi, Y.5    Hunter, C.A.6
  • 19
    • 84879162127 scopus 로고    scopus 로고
    • Toxoplasma gondii proliferation require [sic] down-regulation of host Nox4 expression via activation of PI3 kinase/Akt signaling pathway
    • Zhou W, Quan JH, Lee YH, Shin DW, Cha GH. 2013. Toxoplasma gondii proliferation require [sic] down-regulation of host Nox4 expression via activation of PI3 kinase/Akt signaling pathway. PLoS One 8:e66306. http://dx.doi.org/10.1371/journal.pone.0066306.
    • (2013) PLoS One , vol.8
    • Zhou, W.1    Quan, J.H.2    Lee, Y.H.3    Shin, D.W.4    Cha, G.H.5
  • 20
    • 0036120221 scopus 로고    scopus 로고
    • Dendritic cells as effector cells: gamma interferon activation of murine dendritic cells triggers oxygendependent inhibition of Toxoplasma gondii replication
    • Aline F, Bout D, Dimier-Poisson I. 2002. Dendritic cells as effector cells: gamma interferon activation of murine dendritic cells triggers oxygendependent inhibition of Toxoplasma gondii replication. Infect Immun 70: 2368-2374. http://dx.doi.org/10.1128/IAI.70.5.2368-2374.2002.
    • (2002) Infect Immun , vol.70 , pp. 2368-2374
    • Aline, F.1    Bout, D.2    Dimier-Poisson, I.3
  • 21
    • 84863847438 scopus 로고    scopus 로고
    • Reactive oxygen species-triggered trophoblast apoptosis is initiated by endoplasmic reticulum stress via activation of caspase-12, CHOP, and the JNK pathway in Toxoplasma gondii infection in mice
    • Xu X, Liu T, Zhang A, Huo X, Luo Q, Chen Z, Yu L, Li Q, Liu L, Lun ZR, Shen J. 2012. Reactive oxygen species-triggered trophoblast apoptosis is initiated by endoplasmic reticulum stress via activation of caspase-12, CHOP, and the JNK pathway in Toxoplasma gondii infection in mice. Infect Immun 80:2121-2132. http://dx.doi.org/10.1128/IAI.06295-11.
    • (2012) Infect Immun , vol.80 , pp. 2121-2132
    • Xu, X.1    Liu, T.2    Zhang, A.3    Huo, X.4    Luo, Q.5    Chen, Z.6    Yu, L.7    Li, Q.8    Liu, L.9    Lun, Z.R.10    Shen, J.11
  • 25
    • 33750114685 scopus 로고    scopus 로고
    • Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondii
    • Kim JY, Ahn MH, Song HO, Choi JH, Ryu JS, Min DY, Cho MH. 2006. Involvement of MAPK activation in chemokine or COX-2 productions by Toxoplasma gondii. Korean J Parasitol 44:197-207. http://dx.doi.org/10.3347/kjp.2006.44.3.197.
    • (2006) Korean J Parasitol , vol.44 , pp. 197-207
    • Kim, J.Y.1    Ahn, M.H.2    Song, H.O.3    Choi, J.H.4    Ryu, J.S.5    Min, D.Y.6    Cho, M.H.7
  • 26
    • 84873328380 scopus 로고    scopus 로고
    • Galectin-3 is essential for reactive oxygen species production by peritoneal neutrophils from mice infected with a virulent strain of Toxoplasma gondii
    • Alves CM, Silva DA, Azzolini AE, Marzocchi-Machado CM, Lucisano-Valim YM, Roque-Barreira MC, Mineo JR. 2013. Galectin-3 is essential for reactive oxygen species production by peritoneal neutrophils from mice infected with a virulent strain of Toxoplasma gondii. Parasitology 140:210-219. http://dx.doi.org/10.1017/S0031182012001473.
    • (2013) Parasitology , vol.140 , pp. 210-219
    • Alves, C.M.1    Silva, D.A.2    Azzolini, A.E.3    Marzocchi-Machado, C.M.4    Lucisano-Valim, Y.M.5    Roque-Barreira, M.C.6    Mineo, J.R.7
  • 28
    • 43349086813 scopus 로고    scopus 로고
    • TRAF6 distinctively mediates MyD88-and IRAK-1-induced activation of NF-kappaB
    • Muroi M, Tanamoto K. 2008. TRAF6 distinctively mediates MyD88-and IRAK-1-induced activation of NF-kappaB. J Leukoc Biol 83:702-707.
    • (2008) J Leukoc Biol , vol.83 , pp. 702-707
    • Muroi, M.1    Tanamoto, K.2
  • 29
    • 84861732291 scopus 로고    scopus 로고
    • Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily
    • Ferrao R, Li J, Bergamin E, Wu H. 2012. Structural insights into the assembly of large oligomeric signalosomes in the Toll-like receptor-interleukin-1 receptor superfamily. Sci Signal 5:re3. http://dx.doi.org/10.1126/scisignal.2003124.
    • (2012) Sci Signal , vol.5
    • Ferrao, R.1    Li, J.2    Bergamin, E.3    Wu, H.4
  • 30
    • 79952789527 scopus 로고    scopus 로고
    • UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii
    • Pifer R, Benson A, Sturge CR, Yarovinsky F. 2011. UNC93B1 is essential for TLR11 activation and IL-12-dependent host resistance to Toxoplasma gondii. J Biol Chem 286:3307-3314. http://dx.doi.org/10.1074/jbc.M110.171025.
    • (2011) J Biol Chem , vol.286 , pp. 3307-3314
    • Pifer, R.1    Benson, A.2    Sturge, C.R.3    Yarovinsky, F.4
  • 32
    • 84883444752 scopus 로고    scopus 로고
    • Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15
    • Gov L, Karimzadeh A, Ueno N, Lodoen MB. 2013. Human innate immunity to Toxoplasma gondii is mediated by host caspase-1 and ASC and parasite GRA15. mBio 4:e00255-13. http://dx.doi.org/10.1128/mBio.00255-13.
    • (2013) mBio , vol.4
    • Gov, L.1    Karimzadeh, A.2    Ueno, N.3    Lodoen, M.B.4
  • 35
    • 84928672338 scopus 로고    scopus 로고
    • Toxoplasma gondii isolate with genotype Chinese 1 triggers trophoblast apoptosis through oxidative stress and mitochondrial dysfunction in mice
    • Xu X, He L, Zhang A, Li Q, Hu W, Chen H, Du J, Shen J. 2015. Toxoplasma gondii isolate with genotype Chinese 1 triggers trophoblast apoptosis through oxidative stress and mitochondrial dysfunction in mice. Exp Parasitol 154:51-61. http://dx.doi.org/10.1016/j.exppara.2015.04.008.
    • (2015) Exp Parasitol , vol.154 , pp. 51-61
    • Xu, X.1    He, L.2    Zhang, A.3    Li, Q.4    Hu, W.5    Chen, H.6    Du, J.7    Shen, J.8
  • 37
    • 80054792189 scopus 로고    scopus 로고
    • Toxoplasma gondii effectors are master regulators of the inflammatory response
    • Melo MB, Jensen KD, Saeij JP. 2011. Toxoplasma gondii effectors are master regulators of the inflammatory response. Trends Parasitol 27:487-495 http://dx.doi.org/10.1016/j.pt.2011.08.001.
    • (2011) Trends Parasitol , vol.27 , pp. 487-495
    • Melo, M.B.1    Jensen, K.D.2    Saeij, J.P.3
  • 38
    • 78651504365 scopus 로고    scopus 로고
    • Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein
    • Rosowski EE, Lu D, Julien L, Rodda L, Gaiser RA, Jensen KD, Saeij JP. 2011 Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein. J Exp Med 208:195-212. http://dx.doi.org/10.1084/jem.20100717.
    • (2011) J Exp Med , vol.208 , pp. 195-212
    • Rosowski, E.E.1    Lu, D.2    Julien, L.3    Rodda, L.4    Gaiser, R.A.5    Jensen, K.D.6    Saeij, J.P.7
  • 39
    • 39049193076 scopus 로고    scopus 로고
    • Interactions between secreted GRA proteins and host cell proteins across the parasitophorous vacuolar membrane in the parasitism of Toxoplasma gondii
    • Ahn HJ, Kim S, Kim HE, Nam HW. 2006. Interactions between secreted GRA proteins and host cell proteins across the parasitophorous vacuolar membrane in the parasitism of Toxoplasma gondii. Korean J Parasitol 44:303-312. http://dx.doi.org/10.3347/kjp.2006.44.4.303.
    • (2006) Korean J Parasitol , vol.44 , pp. 303-312
    • Ahn, H.J.1    Kim, S.2    Kim, H.E.3    Nam, H.W.4
  • 42
    • 78650210471 scopus 로고    scopus 로고
    • Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii
    • Steinfeldt T, Könen-Waisman S, Tong L, Pawlowski N, Lamkemeyer T, Sibley LD, Hunn JP, Howard JC. 2010. Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii. PLoS Biol 8:e1000576. http://dx.doi.org/10.1371/journal.pbio.1000576.
    • (2010) PLoS Biol , vol.8
    • Steinfeldt, T.1    Könen-Waisman, S.2    Tong, L.3    Pawlowski, N.4    Lamkemeyer, T.5    Sibley, L.D.6    Hunn, J.P.7    Howard, J.C.8
  • 43
    • 84870848874 scopus 로고    scopus 로고
    • The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18
    • Behnke MS, Fentress SJ, Mashayekhi M, Li LX, Taylor GA, Sibley LD. 2012 The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18. PLoS Pathog 8:e1002992. http://dx.doi.org/10.1371/journal.ppat.1002992.
    • (2012) PLoS Pathog , vol.8
    • Behnke, M.S.1    Fentress, S.J.2    Mashayekhi, M.3    Li, L.X.4    Taylor, G.A.5    Sibley, L.D.6
  • 46
    • 84887340478 scopus 로고    scopus 로고
    • Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse
    • Lilue J, Muller UB, Steinfeldt T, Howard JC. 2013. Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse. Elife 2:e01298. http://dx.doi.org/10.7554/eLife.01298.
    • (2013) Elife , vol.2
    • Lilue, J.1    Muller, U.B.2    Steinfeldt, T.3    Howard, J.C.4
  • 47
    • 84901029147 scopus 로고    scopus 로고
    • The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice
    • Etheridge RD, Alaganan A, Tang K, Lou HJ, Turk BE, Sibley LD. 2014 The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice. Cell Host Microbe 15:537-550. http://dx.doi.org/10.1016/j.chom.2014.04.002.
    • (2014) Cell Host Microbe , vol.15 , pp. 537-550
    • Etheridge, R.D.1    Alaganan, A.2    Tang, K.3    Lou, H.J.4    Turk, B.E.5    Sibley, L.D.6
  • 48
    • 57349192061 scopus 로고    scopus 로고
    • The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4
    • Dunn JD, Ravindran S, Kim SK, Boothroyd JC. 2008. The Toxoplasma gondii dense granule protein GRA7 is phosphorylated upon invasion and forms an unexpected association with the rhoptry proteins ROP2 and ROP4. Infect Immun 76:5853-5861. http://dx.doi.org/10.1128/IAI.01667-07.
    • (2008) Infect Immun , vol.76 , pp. 5853-5861
    • Dunn, J.D.1    Ravindran, S.2    Kim, S.K.3    Boothroyd, J.C.4
  • 49
    • 84955076988 scopus 로고    scopus 로고
    • The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7
    • 6 August
    • Hermanns T, Müller UB, Könen-Waisman S, Howard JC, Steinfeldt T. 6 August 2015. The Toxoplasma gondii rhoptry protein ROP18 is an Irga6-specific kinase and regulated by the dense granule protein GRA7. Cell Microbiol http://dx.doi.org/10.1111/cmi.12499.
    • (2015) Cell Microbiol
    • Hermanns, T.1    Müller, U.B.2    Könen-Waisman, S.3    Howard, J.C.4    Steinfeldt, T.5
  • 50
    • 46249124976 scopus 로고    scopus 로고
    • Deubiquitylation and regulation of the immune response
    • Sun SC. 2008. Deubiquitylation and regulation of the immune response. Nat Rev Immunol 8:501-511. http://dx.doi.org/10.1038/nri2337.
    • (2008) Nat Rev Immunol , vol.8 , pp. 501-511
    • Sun, S.C.1


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