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Volumn 6, Issue , 2016, Pages

Glutamatergic axon-derived BDNF controls GABAergic synaptic differentiation in the cerebellum

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CONTACTIN 1; GLUTAMIC ACID;

EID: 84957567340     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20201     Document Type: Article
Times cited : (31)

References (60)
  • 1
    • 32644451922 scopus 로고    scopus 로고
    • Neurotrophin signalling in health and disease
    • Chao, M. V., Rajagopal, R. & Lee, F. S. Neurotrophin signalling in health and disease. Clinical Sci 110, 167-173 (2006).
    • (2006) Clinical Sci , vol.110 , pp. 167-173
    • Chao, M.V.1    Rajagopal, R.2    Lee, F.S.3
  • 2
    • 84887329131 scopus 로고    scopus 로고
    • The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition
    • Bloodgood, B. L. et al. The activity-dependent transcription factor NPAS4 regulates domain-specific inhibition. Nature 503, 121-125 (2013).
    • (2013) Nature , vol.503 , pp. 121-125
    • Bloodgood, B.L.1
  • 3
    • 84878864672 scopus 로고    scopus 로고
    • ProBDNF and mature BDNF as punishment and reward signals for synapse elimination at mouse neuromuscular junctions
    • Je, H. S. et al. ProBDNF and mature BDNF as punishment and reward signals for synapse elimination at mouse neuromuscular junctions. J Neurosci 33, 9957-9962 (2013).
    • (2013) J Neurosci , vol.33 , pp. 9957-9962
    • Je, H.S.1
  • 4
    • 84859366504 scopus 로고    scopus 로고
    • Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation
    • Kaneko, M., Xie, Y., An, J. J., Stryker, M. P. & Xu, B. Dendritic BDNF synthesis is required for late-phase spine maturation and recovery of cortical responses following sensory deprivation. J Neurosci 32, 4790-4802 (2012).
    • (2012) J Neurosci , vol.32 , pp. 4790-4802
    • Kaneko, M.1    Xie, Y.2    An, J.J.3    Stryker, M.P.4    Xu, B.5
  • 5
    • 59049095242 scopus 로고    scopus 로고
    • Control of extracellular cleavage of ProBDNF by high frequency neuronal activity
    • Nagappan, G. et al. Control of extracellular cleavage of ProBDNF by high frequency neuronal activity. Proc Natl Acad Sci USA 106, 1267-1272 (2009).
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 1267-1272
    • Nagappan, G.1
  • 6
    • 84919417240 scopus 로고    scopus 로고
    • Essential role of presynaptic NMDA receptors in activity-dependent BDNF secretion and corticostriatal LTP
    • Park, H., Popescu, A. & Poo, M. M. Essential role of presynaptic NMDA receptors in activity-dependent BDNF secretion and corticostriatal LTP. Neuron 84, 1009-1022 (2014).
    • (2014) Neuron , vol.84 , pp. 1009-1022
    • Park, H.1    Popescu, A.2    Poo, M.M.3
  • 7
    • 33749010358 scopus 로고    scopus 로고
    • Neurotrophin-regulated signalling pathways
    • Reichardt, L. F. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 361, 1545-1564 (2006).
    • (2006) Philos Trans R Soc Lond B Biol Sci , vol.361 , pp. 1545-1564
    • Reichardt, L.F.1
  • 8
    • 84861693054 scopus 로고    scopus 로고
    • Sustained expression of brain-derived neurotrophic factor is required for maintenance of dendritic spines and normal behavior
    • Vigers, A. J. et al. Sustained expression of brain-derived neurotrophic factor is required for maintenance of dendritic spines and normal behavior. Neurosci 212, 1-18 (2012).
    • (2012) Neurosci , vol.212 , pp. 1-18
    • Vigers, A.J.1
  • 9
    • 79951993695 scopus 로고    scopus 로고
    • TrkB (tropomyosin-related kinase B) controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex
    • Chen, A. I. et al. TrkB (tropomyosin-related kinase B) controls the assembly and maintenance of GABAergic synapses in the cerebellar cortex. J Neurosci 31, 2769-2780 (2011).
    • (2011) J Neurosci , vol.31 , pp. 2769-2780
    • Chen, A.I.1
  • 10
    • 84879081935 scopus 로고    scopus 로고
    • Coupling between GABA-A receptor and chloride transporter underlies ionic plasticity in cerebellar Purkinje neurons
    • Huang, Y., Wang, J. J. & Yung, W. H. Coupling between GABA-A receptor and chloride transporter underlies ionic plasticity in cerebellar Purkinje neurons. Cerebellum 12, 328-330 (2013).
    • (2013) Cerebellum , vol.12 , pp. 328-330
    • Huang, Y.1    Wang, J.J.2    Yung, W.H.3
  • 11
    • 0029807584 scopus 로고    scopus 로고
    • TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons
    • Minichiello, L. & Klein, R. TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes and Dev 10, 2849-2858 (1996).
    • (1996) Genes and Dev , vol.10 , pp. 2849-2858
    • Minichiello, L.1    Klein, R.2
  • 12
    • 0036176884 scopus 로고    scopus 로고
    • TrkB receptor signaling is required for establishment of GABAergic synapses in the cerebellum
    • Rico, B., Xu, B. & Reichardt, L. F. TrkB receptor signaling is required for establishment of GABAergic synapses in the cerebellum. Nat Neurosci 5, 225-233 (2002).
    • (2002) Nat Neurosci , vol.5 , pp. 225-233
    • Rico, B.1    Xu, B.2    Reichardt, L.F.3
  • 13
    • 33847784737 scopus 로고    scopus 로고
    • Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release
    • Sadakata, T. et al. Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release. J Neurosci 27, 2472-2482 (2007).
    • (2007) J Neurosci , vol.27 , pp. 2472-2482
    • Sadakata, T.1
  • 14
    • 80051709985 scopus 로고    scopus 로고
    • TrkB and protein kinase Mzeta regulate synaptic localization of PSD-95 in developing cortex
    • Yoshii, A. et al. TrkB and protein kinase Mzeta regulate synaptic localization of PSD-95 in developing cortex. J Neurosci 31, 11894-11904 (2011).
    • (2011) J Neurosci , vol.31 , pp. 11894-11904
    • Yoshii, A.1
  • 15
    • 34250807034 scopus 로고    scopus 로고
    • Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors
    • Zhou, P. et al. Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Neuron 55, 53-68 (2007).
    • (2007) Neuron , vol.55 , pp. 53-68
    • Zhou, P.1
  • 16
    • 16444381512 scopus 로고    scopus 로고
    • PLCgamma signaling underlies BDNF potentiation of Purkinje cell responses to GABA
    • Cheng, Q. & Yeh, H. H. PLCgamma signaling underlies BDNF potentiation of Purkinje cell responses to GABA. J Neurosci Res 79, 616-627 (2005).
    • (2005) J Neurosci Res , vol.79 , pp. 616-627
    • Cheng, Q.1    Yeh, H.H.2
  • 17
    • 26844525094 scopus 로고    scopus 로고
    • Neuronal depolarization controls brain-derived neurotrophic factor-induced upregulation of NR2C NMDA receptor via calcineurin signaling
    • Suzuki, K., Sato, M., Morishima, Y. & Nakanishi, S. Neuronal depolarization controls brain-derived neurotrophic factor-induced upregulation of NR2C NMDA receptor via calcineurin signaling. J Neurosci 25, 9535-9543 (2005).
    • (2005) J Neurosci , vol.25 , pp. 9535-9543
    • Suzuki, K.1    Sato, M.2    Morishima, Y.3    Nakanishi, S.4
  • 18
    • 46149100739 scopus 로고    scopus 로고
    • Distinct role of long 3 UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons
    • An, J. J. et al. Distinct role of long 3 UTR BDNF mRNA in spine morphology and synaptic plasticity in hippocampal neurons. Cell 134, 175-187 (2008).
    • (2008) Cell , vol.134 , pp. 175-187
    • An, J.J.1
  • 19
    • 67349113528 scopus 로고    scopus 로고
    • Synaptotagmin-IV modulates synaptic function and long-Term potentiation by regulating BDNF release
    • Dean, C. et al. Synaptotagmin-IV modulates synaptic function and long-Term potentiation by regulating BDNF release. Nat Neurosci 12, 767-776 (2009).
    • (2009) Nat Neurosci , vol.12 , pp. 767-776
    • Dean, C.1
  • 20
    • 0037462449 scopus 로고    scopus 로고
    • The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
    • Egan, M. F. et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 112, 257-269 (2003).
    • (2003) Cell , vol.112 , pp. 257-269
    • Egan, M.F.1
  • 21
    • 52049117013 scopus 로고    scopus 로고
    • A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibition
    • Hong, E. J., McCord, A. E. & Greenberg, M. E. A biological function for the neuronal activity-dependent component of Bdnf transcription in the development of cortical inhibition. Neuron 60, 610-624 (2008).
    • (2008) Neuron , vol.60 , pp. 610-624
    • Hong, E.J.1    McCord, A.E.2    Greenberg, M.E.3
  • 22
    • 79960687631 scopus 로고    scopus 로고
    • JIP3 mediates TrkB axonal anterograde transport and enhances BDNF signaling by directly bridging TrkB with kinesin-1
    • Huang, S. H. et al. JIP3 mediates TrkB axonal anterograde transport and enhances BDNF signaling by directly bridging TrkB with kinesin-1. J Neurosci 31, 10602-10614 (2011).
    • (2011) J Neurosci , vol.31 , pp. 10602-10614
    • Huang, S.H.1
  • 23
    • 84884776465 scopus 로고    scopus 로고
    • Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development
    • Ouyang, Q. et al. Christianson syndrome protein NHE6 modulates TrkB endosomal signaling required for neuronal circuit development. Neuron 80, 97-112 (2013).
    • (2013) Neuron , vol.80 , pp. 97-112
    • Ouyang, Q.1
  • 24
    • 79961161973 scopus 로고    scopus 로고
    • Severe alterations of cerebellar cortical development after constitutive activation of Wnt signaling in granule neuron precursors
    • Lorenz, A. et al. Severe alterations of cerebellar cortical development after constitutive activation of Wnt signaling in granule neuron precursors. Mol Cell Biol 31, 3326-3338 (2011).
    • (2011) Mol Cell Biol , vol.31 , pp. 3326-3338
    • Lorenz, A.1
  • 26
    • 0027491104 scopus 로고
    • Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death
    • Klein, R. et al. Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75, 113-122 (1993).
    • (1993) Cell , vol.75 , pp. 113-122
    • Klein, R.1
  • 27
    • 0031017680 scopus 로고    scopus 로고
    • Immunocytochemical localization of TrkB in the central nervous system of the adult rat
    • Yan, Q. et al. Immunocytochemical localization of TrkB in the central nervous system of the adult rat. J Comp Neurol 378, 135-157 (1997).
    • (1997) J Comp Neurol , vol.378 , pp. 135-157
    • Yan, Q.1
  • 28
    • 0032848464 scopus 로고    scopus 로고
    • Transgenic brain-derived neurotrophic factor modulates a developing cerebellar inhibitory synapse
    • Bao, S., Chen, L., Qiao, X. & Thompson, R. F. Transgenic brain-derived neurotrophic factor modulates a developing cerebellar inhibitory synapse. Learn Mem 6, 276-283 (1999).
    • (1999) Learn Mem , vol.6 , pp. 276-283
    • Bao, S.1    Chen, L.2    Qiao, X.3    Thompson, R.F.4
  • 29
    • 84899761760 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes gephyrin protein expression and GABAA receptor clustering in immature cultured hippocampal cells
    • Gonzalez, M. I. Brain-derived neurotrophic factor promotes gephyrin protein expression and GABAA receptor clustering in immature cultured hippocampal cells. Neurochem Int 72, 14-21 (2014).
    • (2014) Neurochem Int , vol.72 , pp. 14-21
    • Gonzalez, M.I.1
  • 30
    • 84898475018 scopus 로고    scopus 로고
    • High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons
    • Andreska, T., Aufmkolk, S., Sauer, M. & Blum, R. High abundance of BDNF within glutamatergic presynapses of cultured hippocampal neurons. Front Cell Neurosci 8, 107 (2014).
    • (2014) Front Cell Neurosci , vol.8 , pp. 107
    • Andreska, T.1    Aufmkolk, S.2    Sauer, M.3    Blum, R.4
  • 31
    • 84860280494 scopus 로고    scopus 로고
    • BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons
    • Dieni, S. et al. BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons. J Cell Biol 196, 775-788 (2012).
    • (2012) J Cell Biol , vol.196 , pp. 775-788
    • Dieni, S.1
  • 32
    • 0035882477 scopus 로고    scopus 로고
    • Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression
    • Farinas, I. et al. Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression. The Journal of Neuroscience 21, 6170-6180 (2001).
    • (2001) The Journal of Neuroscience , vol.21 , pp. 6170-6180
    • Farinas, I.1
  • 33
    • 0024274598 scopus 로고
    • Quantitative morphology and synaptology of cerebellar glomeruli in the rat
    • Jakab, R. L. & Hamori, J. Quantitative morphology and synaptology of cerebellar glomeruli in the rat. Anat Embryol (Berl) 179, 81-88 (1988).
    • (1988) Anat Embryol (Berl) , vol.179 , pp. 81-88
    • Jakab, R.L.1    Hamori, J.2
  • 35
    • 0032481124 scopus 로고    scopus 로고
    • Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
    • Danielian, P. S., Muccino, D., Rowitch, D. H., Michael, S. K. & McMahon, A. P. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol 8, 1323-1326 (1998).
    • (1998) Curr Biol , vol.8 , pp. 1323-1326
    • Danielian, P.S.1    Muccino, D.2    Rowitch, D.H.3    Michael, S.K.4    McMahon, A.P.5
  • 36
    • 0031004888 scopus 로고    scopus 로고
    • Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS, evidence for anterograde axonal transport
    • Conner, J. M., Lauterborn, J. C., Yan, Q., Gall, C. M. & Varon, S. Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS, evidence for anterograde axonal transport. J Neurosci 17, 2295-2313 (1997).
    • (1997) J Neurosci , vol.17 , pp. 2295-2313
    • Conner, J.M.1    Lauterborn, J.C.2    Yan, Q.3    Gall, C.M.4    Varon, S.5
  • 37
    • 4644328190 scopus 로고    scopus 로고
    • Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities
    • Harfe, B. D. et al. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 118, 517-528 (2004).
    • (2004) Cell , vol.118 , pp. 517-528
    • Harfe, B.D.1
  • 38
    • 34548363842 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor induces cell surface expression of short-form tenascin R complex in hippocampal postsynapses
    • Maruyama, E. et al. Brain-derived neurotrophic factor induces cell surface expression of short-form tenascin R complex in hippocampal postsynapses. Int J Biochem Cell Biol 39, 1930-1942 (2007).
    • (2007) Int J Biochem Cell Biol , vol.39 , pp. 1930-1942
    • Maruyama, E.1
  • 39
    • 70349459260 scopus 로고    scopus 로고
    • Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit
    • Betley, J. N. et al. Stringent specificity in the construction of a GABAergic presynaptic inhibitory circuit. Cell 139, 161-174 (2009).
    • (2009) Cell , vol.139 , pp. 161-174
    • Betley, J.N.1
  • 40
    • 65249121931 scopus 로고    scopus 로고
    • Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex
    • Sakata, K. et al. Critical role of promoter IV-driven BDNF transcription in GABAergic transmission and synaptic plasticity in the prefrontal cortex. Proc Natl Acad Sci USA 106, 5942-5947 (2009).
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5942-5947
    • Sakata, K.1
  • 41
    • 0037083578 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure
    • Carter, A. R., Chen, C., Schwartz, P. M. & Segal, R. A. Brain-derived neurotrophic factor modulates cerebellar plasticity and synaptic ultrastructure. J Neurosci 22, 1316-1327 (2002).
    • (2002) J Neurosci , vol.22 , pp. 1316-1327
    • Carter, A.R.1    Chen, C.2    Schwartz, P.M.3    Segal, R.A.4
  • 42
    • 44349087637 scopus 로고    scopus 로고
    • Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration
    • Singh, K. K. et al. Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat Neurosci 11, 649-658 (2008).
    • (2008) Nat Neurosci , vol.11 , pp. 649-658
    • Singh, K.K.1
  • 43
    • 23044464168 scopus 로고    scopus 로고
    • Activation of p75NTR by proBDNF facilitates hippocampal long-Term depression
    • Woo, N. H. et al. Activation of p75NTR by proBDNF facilitates hippocampal long-Term depression. Nat Neurosci 8, 1069-1077 (2005).
    • (2005) Nat Neurosci , vol.8 , pp. 1069-1077
    • Woo, N.H.1
  • 44
    • 33847788692 scopus 로고    scopus 로고
    • Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients
    • Sadakata, T. et al. Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients. J Clin Invest 117, 931-943 (2007).
    • (2007) J Clin Invest , vol.117 , pp. 931-943
    • Sadakata, T.1
  • 45
    • 76149121821 scopus 로고    scopus 로고
    • Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth
    • Rauskolb, S. et al. Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. J Neurosci 30, 1739-1749 (2010).
    • (2010) J Neurosci , vol.30 , pp. 1739-1749
    • Rauskolb, S.1
  • 46
    • 41149120733 scopus 로고    scopus 로고
    • Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines
    • Tanaka, J. et al. Protein synthesis and neurotrophin-dependent structural plasticity of single dendritic spines. Science 319, 1683-1687 (2008).
    • (2008) Science , vol.319 , pp. 1683-1687
    • Tanaka, J.1
  • 47
    • 84878152890 scopus 로고    scopus 로고
    • Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation
    • Hiester, B. G., Galati, D. F., Salinas, P. C. & Jones, K. R. Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation. Mol Cell Neurosci 56, 115-127 (2013).
    • (2013) Mol Cell Neurosci , vol.56 , pp. 115-127
    • Hiester, B.G.1    Galati, D.F.2    Salinas, P.C.3    Jones, K.R.4
  • 48
    • 79955652877 scopus 로고    scopus 로고
    • GABAA receptor trafficking-mediated plasticity of inhibitory synapses
    • Luscher, B., Fuchs, T. & Kilpatrick, C. L. GABAA receptor trafficking-mediated plasticity of inhibitory synapses. Neuron 70, 385-409 (2011).
    • (2011) Neuron , vol.70 , pp. 385-409
    • Luscher, B.1    Fuchs, T.2    Kilpatrick, C.L.3
  • 49
    • 79955660254 scopus 로고    scopus 로고
    • PSD-95-like membrane associated guanylate kinases (PSD-MAGUKs) and synaptic plasticity
    • Xu, W. PSD-95-like membrane associated guanylate kinases (PSD-MAGUKs) and synaptic plasticity. Curr Opin Neurobiol 21, 306-312 (2011).
    • (2011) Curr Opin Neurobiol , vol.21 , pp. 306-312
    • Xu, W.1
  • 50
    • 84904742939 scopus 로고    scopus 로고
    • Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling
    • Yoshii, A. & Constantine-Paton, M. Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling. Front Synaptic Neurosci 6, 6 (2014).
    • (2014) Front Synaptic Neurosci , vol.6 , pp. 6
    • Yoshii, A.1    Constantine-Paton, M.2
  • 51
    • 84920426339 scopus 로고    scopus 로고
    • Activity-dependent inhibitory synapse remodeling through gephyrin phosphorylation
    • Flores, C. E. et al. Activity-dependent inhibitory synapse remodeling through gephyrin phosphorylation. Proc Natl Acad Sci USA. 112, E65-72 (2015).
    • (2015) Proc Natl Acad Sci USA , vol.112 , pp. E65-72
    • Flores, C.E.1
  • 52
    • 84897874869 scopus 로고    scopus 로고
    • Gephyrin: A master regulator of neuronal function?
    • Tyagarajan, S. K. & Fritschy, J. M. Gephyrin: A master regulator of neuronal function? Nat Rev Neurosci 15, 141-156 (2014).
    • (2014) Nat Rev Neurosci , vol.15 , pp. 141-156
    • Tyagarajan, S.K.1    Fritschy, J.M.2
  • 53
    • 0037223854 scopus 로고    scopus 로고
    • Signalling and crosstalk of Rho GTPases in mediating axon guidance
    • Yuan, X. B. et al. Signalling and crosstalk of Rho GTPases in mediating axon guidance. Nat Cell Biol 5, 38-45 (2003).
    • (2003) Nat Cell Biol , vol.5 , pp. 38-45
    • Yuan, X.B.1
  • 54
    • 0028274040 scopus 로고
    • Mice lacking brain-derived neurotrophic factor develop with sensory deficits
    • Ernfors, P., Lee, K. F. & Jaenisch, R. Mice lacking brain-derived neurotrophic factor develop with sensory deficits. Nature 368, 147-150 (1994).
    • (1994) Nature , vol.368 , pp. 147-150
    • Ernfors, P.1    Lee, K.F.2    Jaenisch, R.3
  • 55
    • 0034792085 scopus 로고    scopus 로고
    • Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity
    • Rios, M. et al. Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity. Mol Endocrinol 15, 1748-1757 (2001).
    • (2001) Mol Endocrinol , vol.15 , pp. 1748-1757
    • Rios, M.1
  • 56
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano, P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genetics 21, 70-71 (1999).
    • (1999) Nat Genetics , vol.21 , pp. 70-71
    • Soriano, P.1
  • 57
    • 3042856262 scopus 로고    scopus 로고
    • Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
    • Srinivas, S. et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 1, 4 (2001).
    • (2001) BMC Dev Biol , vol.1 , pp. 4
    • Srinivas, S.1
  • 58
    • 0033634813 scopus 로고    scopus 로고
    • Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP
    • Feng, G. et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28, 41-51 (2000).
    • (2000) Neuron , vol.28 , pp. 41-51
    • Feng, G.1
  • 59
    • 84856006967 scopus 로고    scopus 로고
    • Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus
    • Beaudoin, G. M., 3rd et al. Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampus. J Neurosci 32, 99-110 (2012).
    • (2012) J Neurosci , vol.32 , pp. 99-110
    • Beaudoin, G.M.1
  • 60
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini, L., Buchs, P. A. & Muller, D. A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37, 173-182 (1991).
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3


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