D-chiro-inositol glycan reduces food intake by regulating hypothalamic neuropeptide expression via AKT-FoxO1 pathway

Biochemical and Biophysical Research Communications

Volumn 470, Issue 4, 2016, Pages 818-823

  Jeon, Yoonjeong ^a   Aja, Susan ^b   Ronnett, Gabriele V ^a,b,c   Kim, Eun Kyoung ^a  

^a Daegu Gyeongbuk Institute of Science and Technology   (South Korea)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

Food intake; INS 2; Neuropeptide Y; Proopiomelanocortin

Indexed keywords

DEXTRO CHIRO INOSITOL GLYCAN; GLYCAN; INSULIN; NEUROPEPTIDE; NEUROPEPTIDE Y; PROOPIOMELANOCORTIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; 4-(2-AMINO-2-DEOXYGALACTOPYRANOSYL)-3-O-METHYLINOSITOL; DISACCHARIDE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; INOSITOL PHOSPHATE; INOSITOL PHOSPHATE GLYCAN; POLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOWN REGULATION; FOOD INTAKE; HYPOTHALAMUS; INFANT; MALE; METABOLIC DISORDER; MOUSE; NERVE CELL; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL LINE; DOSE RESPONSE; DRUG EFFECTS; EATING; GENE EXPRESSION REGULATION; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BODY WEIGHT; CELL LINE; DISACCHARIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HYPOTHALAMUS; INOSITOL PHOSPHATES; INSULIN; MALE; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84957537122     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.01.115     Document Type: Article

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