Insulin directly regulates NPY and AgRP gene expression via the MAPK MEK/ERK signal transduction pathway in mHypoE-46 hypothalamic neurons

Molecular and Cellular Endocrinology

Volumn 307, Issue 1-2, 2009, Pages 99-108

  Mayer, Christopher M ^a   Belsham, Denise D ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Agouti related peptide; Gene expression; Hypothalamus; Insulin receptor; Mitogen activated protein kinase; Neuropeptide Y; Signal transduction

Indexed keywords

AGOUTI RELATED PROTEIN; INSULIN; INSULIN RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NEUROPEPTIDE Y;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; DNA FLANKING REGION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HORMONAL REGULATION; HUMAN; HYPOTHALAMUS; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

5' FLANKING REGION; AGOUTI-RELATED PROTEIN; ANIMALS; BUTADIENES; CELL LINE; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HUMANS; HYPOTHALAMUS; INSULIN; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEURONS; NEUROPEPTIDE Y; NITRILES; PHOSPHORYLATION; PLASMIDS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REGULATORY SEQUENCES, NUCLEIC ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 67349115357     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2009.02.031     Document Type: Article

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