Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice

Diabetologia

Volumn 59, Issue 3, 2016, Pages 522-532

  Cavelti Weder, Claudia ^a   Li, Weida ^b,c   Zumsteg, Adrian ^c   Stemann Andersen, Marianne ^a   Zhang, Yuemei ^c   Yamada, Takatsugu ^a   Wang, Max ^c   Lu, Jiaqi ^c   Jermendy, Agnes ^a   Bee, Yong Mong ^a   Bonner Weir, Susan ^a   Weir, Gordon C ^a   Zhou, Qiao ^c  

^a JOSLIN DIABETES CENTER   (United States)

^b TONGJI UNIVERSITY   (China)

^c Harvard University   (United States)

Author keywords

Diabetes; Exocrine to beta cell reprogramming; Hyperglycaemia

Indexed keywords

ADENOVIRUS VECTOR; CD11B ANTIGEN; CD9 ANTIGEN; GLUCOSE; INSULIN; NEUROGENIN 3; TRANSCRIPTION FACTOR MAFA;

ACINAR CELL; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CONTROLLED STUDY; DRUG IMPLANTATION; DRUG PELLET; EXOCRINE CELL; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IN VIVO STUDY; MACROPHAGE; MALE; MOUSE; MOUSE MODEL; NEPHRECTOMY; NONHUMAN; NUCLEAR REPROGRAMMING; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PANCREATITIS; PHENOTYPE; PRIORITY JOURNAL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; VIRAL GENE DELIVERY SYSTEM; ANIMAL; EXOCRINE PANCREAS; IN VITRO STUDY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CELLULAR REPROGRAMMING; HYPERGLYCEMIA; IN VITRO TECHNIQUES; INSULIN-SECRETING CELLS; MALE; MICE; PANCREAS, EXOCRINE;

EID: 84957442623     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-015-3838-7     Document Type: Article

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