-
1
-
-
71449125977
-
Forcing cells to change lineages
-
Graf, T. & Enver, T. Forcing cells to change lineages. Nature 462, 587-594 (2009).
-
(2009)
Nature
, vol.462
, pp. 587-594
-
-
Graf, T.1
Enver, T.2
-
2
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J. & Melton, D.A. In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455, 627-632 (2008).
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
-
3
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen, T. et al. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 463, 1035-1041 (2010).
-
(2010)
Nature
, vol.463
, pp. 1035-1041
-
-
Vierbuchen, T.1
-
4
-
-
77955321344
-
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
-
Ieda, M. et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 142, 375-386 (2010).
-
(2010)
Cell
, vol.142
, pp. 375-386
-
-
Ieda, M.1
-
5
-
-
77951611220
-
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
-
Thorel, F. et al. Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 464, 1149-1154 (2010).
-
(2010)
Nature
, vol.464
, pp. 1149-1154
-
-
Thorel, F.1
-
6
-
-
84868138400
-
Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression
-
Ginsberg, M. et al. Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell 151, 559-575 (2012).
-
(2012)
Cell
, vol.151
, pp. 559-575
-
-
Ginsberg, M.1
-
7
-
-
84880506680
-
Adult duct-lining cells can reprogram into beta-like cells able to counter repeated cycles of toxin-induced diabetes
-
Al-Hasani, K. et al. Adult duct-lining cells can reprogram into beta-like cells able to counter repeated cycles of toxin-induced diabetes. Dev. Cell 26, 86-100 (2013).
-
(2013)
Dev. Cell
, vol.26
, pp. 86-100
-
-
Al-Hasani, K.1
-
8
-
-
84893761684
-
In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model
-
Guo, Z. et al. In vivo direct reprogramming of reactive glial cells into functional neurons after brain injury and in an Alzheimer's disease model. Cell Stem Cell 14, 188-202 (2014).
-
(2014)
Cell Stem Cell
, vol.14
, pp. 188-202
-
-
Guo, Z.1
-
9
-
-
84892173922
-
Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
-
Baeyens, L. et al. Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nat. Biotechnol. 32, 76-83 (2014).
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 76-83
-
-
Baeyens, L.1
-
10
-
-
84888096421
-
Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells
-
Lee, J. et al. Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells. eLife 2, e00940 (2013).
-
(2013)
eLife
, vol.2
, pp. e00940
-
-
Lee, J.1
-
11
-
-
84866780162
-
Molecular roadblocks for cellular reprogramming
-
Vierbuchen, T. & Wernig, M. Molecular roadblocks for cellular reprogramming. Mol. Cell 47, 827-838 (2012).
-
(2012)
Mol. Cell
, vol.47
, pp. 827-838
-
-
Vierbuchen, T.1
Wernig, M.2
-
12
-
-
85027957068
-
Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5
-
Chen, J.X. et al. Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Circ. Res. 111, 50-55 (2012).
-
(2012)
Circ. Res.
, vol.111
, pp. 50-55
-
-
Chen, J.X.1
-
13
-
-
30944467113
-
A guide to choosing fluorescent proteins
-
Shaner, N.C., Steinbach, P.A. & Tsien, R.Y. A guide to choosing fluorescent proteins. Nat. Methods 2, 905-909 (2005).
-
(2005)
Nat. Methods
, vol.2
, pp. 905-909
-
-
Shaner, N.C.1
Steinbach, P.A.2
Tsien, R.Y.3
-
14
-
-
24144473869
-
Very slow turnover of beta-cells in aged adult mice
-
Teta, M., Long, S.Y., Wartschow, L.M., Rankin, M.M. & Kushner, J.A. Very slow turnover of beta-cells in aged adult mice. Diabetes 54, 2557-2567 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 2557-2567
-
-
Teta, M.1
Long, S.Y.2
Wartschow, L.M.3
Rankin, M.M.4
Kushner, J.A.5
-
15
-
-
34250858628
-
All β cells contribute equally to islet growth and maintenance
-
Brennand, K., Huangfu, D. & Melton, D. All β cells contribute equally to islet growth and maintenance. PLoS Biol. 5, e163 (2007).
-
(2007)
PLoS Biol.
, vol.5
, pp. e163
-
-
Brennand, K.1
Huangfu, D.2
Melton, D.3
-
16
-
-
0028330011
-
Transplanted beta cell response to increased metabolic demand. Changes in beta cell replication and mass
-
Montaña, E., Bonner-Weir, S. & Weir, G.C. Transplanted beta cell response to increased metabolic demand. Changes in beta cell replication and mass. J. Clin. Invest. 93, 1577-1582 (1994).
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1577-1582
-
-
Montaña, E.1
Bonner-Weir, S.2
Weir, G.C.3
-
17
-
-
0033770540
-
Life and death of the pancreatic β cells
-
Bonner-Weir, S. Life and death of the pancreatic β cells. Trends Endocrinol. Metab. 11, 375-378 (2000).
-
(2000)
Trends Endocrinol. Metab.
, vol.11
, pp. 375-378
-
-
Bonner-Weir, S.1
-
18
-
-
0028558590
-
Beneficial influence of glycemic control upon the growth and function of transplanted islets
-
Juang, J.H., Bonner-Weir, S., Wu, Y.J. & Weir, G.C. Beneficial influence of glycemic control upon the growth and function of transplanted islets. Diabetes 43, 1334-1339 (1994).
-
(1994)
Diabetes
, vol.43
, pp. 1334-1339
-
-
Juang, J.H.1
Bonner-Weir, S.2
Wu, Y.J.3
Weir, G.C.4
-
19
-
-
0027502147
-
Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice
-
Montaña, E., Bonner-Weir, S. & Weir, G.C. Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice. J. Clin. Invest. 91, 780-787 (1993).
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 780-787
-
-
Montaña, E.1
Bonner-Weir, S.2
Weir, G.C.3
-
20
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner, A. et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454, 766-770 (2008).
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
-
21
-
-
84899800252
-
In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes
-
Li, W. et al. In vivo reprogramming of pancreatic acinar cells to three islet endocrine subtypes. eLife 3, e01846 (2014).
-
(2014)
eLife
, vol.3
, pp. e01846
-
-
Li, W.1
-
22
-
-
84857975722
-
Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3
-
Blum, B. et al. Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3. Nat. Biotechnol. 30, 261-264 (2012).
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 261-264
-
-
Blum, B.1
-
23
-
-
0029793745
-
Cadherins regulate aggregation of pancreatic beta-cells in vivo
-
Dahl, U., Sjodin, A. & Semb, H. Cadherins regulate aggregation of pancreatic beta-cells in vivo. Development 122, 2895-2902 (1996).
-
(1996)
Development
, vol.122
, pp. 2895-2902
-
-
Dahl, U.1
Sjodin, A.2
Semb, H.3
-
24
-
-
0022375778
-
Structure-function relationships in pancreatic islets: Support for intraislet modulation of insulin secretion
-
Hopcroft, D.W., Mason, D.R. & Scott, R.S. Structure-function relationships in pancreatic islets: support for intraislet modulation of insulin secretion. Endocrinology 117, 2073-2080 (1985).
-
(1985)
Endocrinology
, vol.117
, pp. 2073-2080
-
-
Hopcroft, D.W.1
Mason, D.R.2
Scott, R.S.3
-
25
-
-
0025149615
-
Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells
-
Meda, P. et al. Rapid and reversible secretion changes during uncoupling of rat insulin-producing cells. J. Clin. Invest. 86, 759-768 (1990).
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 759-768
-
-
Meda, P.1
-
26
-
-
20044389102
-
Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release
-
Ravier, M.A. et al. Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2+ and insulin oscillations, and basal insulin release. Diabetes 54, 1798-1807 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 1798-1807
-
-
Ravier, M.A.1
-
27
-
-
34147163066
-
EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets
-
Konstantinova, I. et al. EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell 129, 359-370 (2007).
-
(2007)
Cell
, vol.129
, pp. 359-370
-
-
Konstantinova, I.1
-
28
-
-
84857888840
-
Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA
-
Akinci, E., Banga, A., Greder, L.V., Dutton, J.R. & Slack, J.M. Reprogramming of pancreatic exocrine cells towards a beta (β) cell character using Pdx1, Ngn3 and MafA. Biochem. J. 442, 539-550 (2012).
-
(2012)
Biochem. J.
, vol.442
, pp. 539-550
-
-
Akinci, E.1
Banga, A.2
Greder, L.V.3
Dutton, J.R.4
Slack, J.M.5
-
29
-
-
84866550121
-
In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts
-
Banga, A., Akinci, E., Greder, L.V., Dutton, J.R. & Slack, J.M. In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts. Proc. Natl. Acad. Sci. USA 109, 15336-15341 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 15336-15341
-
-
Banga, A.1
Akinci, E.2
Greder, L.V.3
Dutton, J.R.4
Slack, J.M.5
-
30
-
-
84897030116
-
De novo formation of insulin-producing "neo-beta cell islets" from intestinal crypts
-
Chen, Y.J. et al. De novo formation of insulin-producing "neo-beta cell islets" from intestinal crypts. Cell Reports 6, 1046-1058 (2014).
-
(2014)
Cell Reports
, vol.6
, pp. 1046-1058
-
-
Chen, Y.J.1
-
31
-
-
0023224147
-
Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection
-
Gotoh, M. et al. Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection. Transplantation 43, 725-730 (1987).
-
(1987)
Transplantation
, vol.43
, pp. 725-730
-
-
Gotoh, M.1
-
32
-
-
84921424912
-
Direct lineage conversion of pancreatic exocrine to endocrine beta cells in vivo with defined factors
-
Cavelti-Weder, C., Li, W., Weir, G.C. & Zhou, Q. Direct lineage conversion of pancreatic exocrine to endocrine beta cells in vivo with defined factors. Methods Mol. Biol. 1150, 247-262 (2014).
-
(2014)
Methods Mol. Biol.
, vol.1150
, pp. 247-262
-
-
Cavelti-Weder, C.1
Li, W.2
Weir, G.C.3
Zhou, Q.4
-
33
-
-
79952788617
-
Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling
-
Gu, H. et al. Preparation of reduced representation bisulfite sequencing libraries for genome-scale DNA methylation profiling. Nat. Protoc. 6, 468-481 (2011).
-
(2011)
Nat. Protoc.
, vol.6
, pp. 468-481
-
-
Gu, H.1
-
34
-
-
4544341015
-
Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
-
Smyth, G.K. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat. Appl. Genet. Molec. Biol. 3, 3 (2004).
-
(2004)
Stat. Appl. Genet. Molec. Biol.
, vol.3
, pp. 3
-
-
Smyth, G.K.1
|