A New Pathway for Senescence Regulation

Genomics, Proteomics and Bioinformatics

Volumn 13, Issue 6, 2015, Pages 333-335

  Cao, Xi ^a   Li, Mo ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; ATR PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1A; TRANSCRIPTION FACTOR GATA 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR INTERACTING PROTEIN 2; UNCLASSIFIED DRUG;

DNA DAMAGE; ECTOPIC EXPRESSION; EDITORIAL; GENETIC REGULATION; SELECTIVE AUTOPHAGY; SENESCENCE; AGING; ANIMAL; AUTOPHAGY; CELL AGING; GENETICS; HUMAN; INFLAMMATION; METABOLISM;

AGING; ANIMALS; AUTOPHAGY; CELL AGING; DNA DAMAGE; GATA4 TRANSCRIPTION FACTOR; HUMANS; INFLAMMATION;

EID: 84957433643     PISSN: 16720229     EISSN: 22103244     Source Type: Journal    
DOI: 10.1016/j.gpb.2015.11.002     Document Type: Editorial

References (20)

1. Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp Cell Res 1961, 25:585-621.
2. Kang C., Xu Q., Martin T.D., Li M.Z., Demaria M., Aron L., et al. The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. Science 2015, 349:aaa5612.
3. Gonzalez L.C., Ghadaouia S., Martinez A., Rodier F. Premature aging/senescence in cancer cells facing therapy: good or bad?. Biogerontology 2015, 1-17.
4. Collado M., Blasco M.A., Serrano M. Cellular senescence in cancer and aging. Cell 2007, 130:223-233.
5. Green M.R. Senescence: not just for tumor suppression. Cell 2008, 134:562-564.
6. van Deursen J.M. The role of senescent cells in ageing. Nature 2014, 509:439-446.
7. Kuilman T., Michaloglou C., Vredeveld L.C., Douma S., van Doorn R., Desmet C.J., et al. Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 2008, 133:1019-1031.
8. Acosta J.C., O'Loghlen A., Banito A., Guijarro M.V., Augert A., Raguz S., et al. Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 2008, 133:1006-1018.
9. Munoz-Espin D., Serrano M. Cellular senescence: from physiology to pathology. Nat Rev Mol Cell Biol 2014, 15:482-496.
10. Ciccia A., Elledge S.J. The DNA damage response: making it safe to play with knives. Mol Cell 2010, 40:179-204.
11. Lombard D.B., Chua K.F., Mostoslavsky R., Franco S., Gostissa M., Alt F.W. DNA repair, genome stability, and aging. Cell 2005, 120:497-512.
12. Viger R.S., Guittot S.M., Anttonen M., Wilson D.B., Heikinheimo M. Role of the GATA family of transcription factors in endocrine development, function, and disease. Mol Endocrinol 2008, 22:781-798.
13. Aries A., Whitcomb J., Shao W., Komati H., Saleh M., Nemer M. Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate. Cell Death Dis 2014, 5:e1566.
14. Brown J.P., Wei W., Sedivy J.M. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. Science 1997, 277:831-834.
15. Sherr C.J., McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002, 2:103-112.
16. Campisi J., d'Adda di Fagagna F. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007, 8:729-740.
17. d'Adda di Fagagna F., Reaper P.M., Clay-Farrace L., Fiegler H., Carr P., Von Zglinicki T., et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003, 426:194-198.
18. Gewirtz D.A. Autophagy and senescence: a partnership in search of definition. Autophagy 2013, 9:808-812.
19. Ivanov A., Pawlikowski J., Manoharan I., van Tuyn J., Nelson D.M., Rai T.S., et al. Lysosome-mediated processing of chromatin in senescence. J Cell Biol 2013, 202:129-143.
20. Kang H.T., Lee K.B., Kim S.Y., Choi H.R., Park S.C. Autophagy impairment induces premature senescence in primary human fibroblasts. PLoS One 2011, 6:e23367.