메뉴 건너뛰기




Volumn 24, Issue 5, 2016, Pages 835-843

Genome-wide DNA methylation profile implicates potential cartilage regeneration at the late stage of knee osteoarthritis

Author keywords

Cartilage; Epigenetics; Methylation; Osteoarthritis

Indexed keywords

BETA CATENIN; GENOMIC DNA; HOMEODOMAIN PROTEIN; MICRORNA; WNT PROTEIN;

EID: 84956939820     PISSN: 10634584     EISSN: 15229653     Source Type: Journal    
DOI: 10.1016/j.joca.2015.12.013     Document Type: Article
Times cited : (37)

References (45)
  • 1
    • 33846213905 scopus 로고    scopus 로고
    • Clinical aspects, pathology and pathophysiology of osteoarthritis
    • Goldring S.R., Goldring M.B. Clinical aspects, pathology and pathophysiology of osteoarthritis. J Musculoskelet Neuronal Interact 2006, 6(4):376-378.
    • (2006) J Musculoskelet Neuronal Interact , vol.6 , Issue.4 , pp. 376-378
    • Goldring, S.R.1    Goldring, M.B.2
  • 3
    • 34249337761 scopus 로고    scopus 로고
    • Perceptions of epigenetics
    • Bird A. Perceptions of epigenetics. Nature 2007, 447(7143):396-398.
    • (2007) Nature , vol.447 , Issue.7143 , pp. 396-398
    • Bird, A.1
  • 4
    • 26844518429 scopus 로고    scopus 로고
    • Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions
    • Roach H.I., Yamada N., Cheung K.S., Tilley S., Clarke N.M., Oreffo R.O., et al. Association between the abnormal expression of matrix-degrading enzymes by human osteoarthritic chondrocytes and demethylation of specific CpG sites in the promoter regions. Arthritis Rheum 2005, 52(10):3110-3124.
    • (2005) Arthritis Rheum , vol.52 , Issue.10 , pp. 3110-3124
    • Roach, H.I.1    Yamada, N.2    Cheung, K.S.3    Tilley, S.4    Clarke, N.M.5    Oreffo, R.O.6
  • 5
    • 84875999020 scopus 로고    scopus 로고
    • Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1beta (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites
    • Hashimoto K., Otero M., Imagawa K., de Andres M.C., Coico J.M., Roach H.I., et al. Regulated transcription of human matrix metalloproteinase 13 (MMP13) and interleukin-1beta (IL1B) genes in chondrocytes depends on methylation of specific proximal promoter CpG sites. J Biol Chem 2013, 288(14):10061-10072.
    • (2013) J Biol Chem , vol.288 , Issue.14 , pp. 10061-10072
    • Hashimoto, K.1    Otero, M.2    Imagawa, K.3    de Andres, M.C.4    Coico, J.M.5    Roach, H.I.6
  • 6
    • 61449135868 scopus 로고    scopus 로고
    • Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation
    • Cheung K.S., Hashimoto K., Yamada N., Roach H.I. Expression of ADAMTS-4 by chondrocytes in the surface zone of human osteoarthritic cartilage is regulated by epigenetic DNA de-methylation. Rheumatol Int 2009, 29(5):525-534.
    • (2009) Rheumatol Int , vol.29 , Issue.5 , pp. 525-534
    • Cheung, K.S.1    Hashimoto, K.2    Yamada, N.3    Roach, H.I.4
  • 9
    • 84922240639 scopus 로고    scopus 로고
    • Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches
    • den Hollander W., Ramos Y.F., Bos S.D., Bomer N., van der Breggen R., Lakenberg N., et al. Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches. Ann Rheum Dis 2014, 73(12):2208-2212.
    • (2014) Ann Rheum Dis , vol.73 , Issue.12 , pp. 2208-2212
    • den Hollander, W.1    Ramos, Y.F.2    Bos, S.D.3    Bomer, N.4    van der Breggen, R.5    Lakenberg, N.6
  • 10
    • 84908381697 scopus 로고    scopus 로고
    • Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage
    • Jeffries M.A., Donica M., Baker L.W., Stevenson M.E., Annan A.C., Humphrey M.B., et al. Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage. Arthritis Rheumatol 2014, 66(10):2804-2815.
    • (2014) Arthritis Rheumatol , vol.66 , Issue.10 , pp. 2804-2815
    • Jeffries, M.A.1    Donica, M.2    Baker, L.W.3    Stevenson, M.E.4    Annan, A.C.5    Humphrey, M.B.6
  • 12
    • 84873175958 scopus 로고    scopus 로고
    • Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees
    • Chou C.H., Lee C.H., Lu L.S., Song I.W., Chuang H.P., Kuo S.Y., et al. Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees. Osteoarthritis Cartilage 2013, 21(3):450-461.
    • (2013) Osteoarthritis Cartilage , vol.21 , Issue.3 , pp. 450-461
    • Chou, C.H.1    Lee, C.H.2    Lu, L.S.3    Song, I.W.4    Chuang, H.P.5    Kuo, S.Y.6
  • 13
    • 84924916657 scopus 로고    scopus 로고
    • Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments
    • Chou C.H., Lee M.T.M., Song I.W., Lu L.S., Shen H.C., Lee C.H., et al. Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments. Osteoarthritis Cartilage 2015, 23(4):571-580.
    • (2015) Osteoarthritis Cartilage , vol.23 , Issue.4 , pp. 571-580
    • Chou, C.H.1    Lee, M.T.M.2    Song, I.W.3    Lu, L.S.4    Shen, H.C.5    Lee, C.H.6
  • 14
    • 84897548625 scopus 로고    scopus 로고
    • Minfi: a flexible and comprehensive bioconductor package for the analysis of infinium DNA methylation microarrays
    • Aryee M.J., Jaffe A.E., Corrada-Bravo H., Ladd-Acosta C., Feinberg A.P., Hansen K.D., et al. Minfi: a flexible and comprehensive bioconductor package for the analysis of infinium DNA methylation microarrays. Bioinformatics 2014, 30(10):1363-1369.
    • (2014) Bioinformatics , vol.30 , Issue.10 , pp. 1363-1369
    • Aryee, M.J.1    Jaffe, A.E.2    Corrada-Bravo, H.3    Ladd-Acosta, C.4    Feinberg, A.P.5    Hansen, K.D.6
  • 15
    • 84862266444 scopus 로고    scopus 로고
    • Complete pipeline for Infinium((R)) human methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation
    • Touleimat N., Tost J. Complete pipeline for Infinium((R)) human methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation. Epigenomics 2012, 4(3):325-341.
    • (2012) Epigenomics , vol.4 , Issue.3 , pp. 325-341
    • Touleimat, N.1    Tost, J.2
  • 16
    • 78649475003 scopus 로고    scopus 로고
    • Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
    • Du P., Zhang X., Huang C.C., Jafari N., Kibbe W.A., Hou L., et al. Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis. BMC Bioinforma 2010, 11:587.
    • (2010) BMC Bioinforma , vol.11 , pp. 587
    • Du, P.1    Zhang, X.2    Huang, C.C.3    Jafari, N.4    Kibbe, W.A.5    Hou, L.6
  • 17
    • 0141453478 scopus 로고    scopus 로고
    • Expression of bone morphogenetic protein 6 in healthy and osteoarthritic human articular chondrocytes and stimulation of matrix synthesis in vitro
    • Bobacz K., Gruber R., Soleiman A., Erlacher L., Smolen J.S., Graninger W.B. Expression of bone morphogenetic protein 6 in healthy and osteoarthritic human articular chondrocytes and stimulation of matrix synthesis in vitro. Arthritis Rheum 2003, 48(9):2501-2508.
    • (2003) Arthritis Rheum , vol.48 , Issue.9 , pp. 2501-2508
    • Bobacz, K.1    Gruber, R.2    Soleiman, A.3    Erlacher, L.4    Smolen, J.S.5    Graninger, W.B.6
  • 18
    • 83755182740 scopus 로고    scopus 로고
    • Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis
    • Wang M., Shen J., Jin H., Im H.J., Sandy J., Chen D. Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis. Ann N Y Acad Sci 2011, 1240:61-69.
    • (2011) Ann N Y Acad Sci , vol.1240 , pp. 61-69
    • Wang, M.1    Shen, J.2    Jin, H.3    Im, H.J.4    Sandy, J.5    Chen, D.6
  • 19
    • 77950021301 scopus 로고    scopus 로고
    • Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis
    • Karlsson C., Dehne T., Lindahl A., Brittberg M., Pruss A., Sittinger M., et al. Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis. Osteoarthritis Cartilage 2010, 18(4):581-592.
    • (2010) Osteoarthritis Cartilage , vol.18 , Issue.4 , pp. 581-592
    • Karlsson, C.1    Dehne, T.2    Lindahl, A.3    Brittberg, M.4    Pruss, A.5    Sittinger, M.6
  • 20
    • 84888873366 scopus 로고    scopus 로고
    • Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis
    • Pesesse L., Sanchez C., Delcour J.P., Bellahcene A., Baudouin C., Msika P., et al. Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis. Osteoarthritis Cartilage 2013, 21(12):1913-1923.
    • (2013) Osteoarthritis Cartilage , vol.21 , Issue.12 , pp. 1913-1923
    • Pesesse, L.1    Sanchez, C.2    Delcour, J.P.3    Bellahcene, A.4    Baudouin, C.5    Msika, P.6
  • 21
    • 84897532806 scopus 로고    scopus 로고
    • Matrilin-2 is a widely distributed extracellular matrix protein and a potential biomarker in the early stage of osteoarthritis in articular cartilage
    • Zhang S., Peng J., Guo Y., Javidiparsijani S., Wang G., Wang Y., et al. Matrilin-2 is a widely distributed extracellular matrix protein and a potential biomarker in the early stage of osteoarthritis in articular cartilage. Biomed Res Int 2014, 2014:986127.
    • (2014) Biomed Res Int , vol.2014 , pp. 986127
    • Zhang, S.1    Peng, J.2    Guo, Y.3    Javidiparsijani, S.4    Wang, G.5    Wang, Y.6
  • 22
    • 12344334669 scopus 로고    scopus 로고
    • The T-box transcription factor Tbx15 is required for skeletal development
    • Singh M.K., Petry M., Haenig B., Lescher B., Leitges M., Kispert A. The T-box transcription factor Tbx15 is required for skeletal development. Mech Dev 2005, 122(2):131-144.
    • (2005) Mech Dev , vol.122 , Issue.2 , pp. 131-144
    • Singh, M.K.1    Petry, M.2    Haenig, B.3    Lescher, B.4    Leitges, M.5    Kispert, A.6
  • 23
    • 84907073808 scopus 로고    scopus 로고
    • Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance
    • Ramos Y.F., Metrustry S., Arden N., Bay-Jensen A.C., Beekman M., de Craen A.J., et al. Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. J Med Genet 2014, 51(9):596-604.
    • (2014) J Med Genet , vol.51 , Issue.9 , pp. 596-604
    • Ramos, Y.F.1    Metrustry, S.2    Arden, N.3    Bay-Jensen, A.C.4    Beekman, M.5    de Craen, A.J.6
  • 24
    • 34250719638 scopus 로고    scopus 로고
    • Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis
    • Min J.L., Meulenbelt I., Kloppenburg M., van Duijn C.M., Slagboom P.E. Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis. Eur J Hum Genet 2007, 15(7):791-799.
    • (2007) Eur J Hum Genet , vol.15 , Issue.7 , pp. 791-799
    • Min, J.L.1    Meulenbelt, I.2    Kloppenburg, M.3    van Duijn, C.M.4    Slagboom, P.E.5
  • 25
    • 84879851334 scopus 로고    scopus 로고
    • Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation
    • Culley K.L., Hui W., Barter M.J., Davidson R.K., Swingler T.E., Destrument A.P., et al. Class I histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation. Arthritis Rheum 2013, 65(7):1822-1830.
    • (2013) Arthritis Rheum , vol.65 , Issue.7 , pp. 1822-1830
    • Culley, K.L.1    Hui, W.2    Barter, M.J.3    Davidson, R.K.4    Swingler, T.E.5    Destrument, A.P.6
  • 26
    • 36949023800 scopus 로고    scopus 로고
    • Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling
    • Hopwood B., Tsykin A., Findlay D.M., Fazzalari N.L. Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling. Arthritis Res Ther 2007, 9(5):R100.
    • (2007) Arthritis Res Ther , vol.9 , Issue.5 , pp. R100
    • Hopwood, B.1    Tsykin, A.2    Findlay, D.M.3    Fazzalari, N.L.4
  • 27
    • 77950860603 scopus 로고    scopus 로고
    • The human alpha11 integrin promoter drives fibroblast-restricted expression in vivo and is regulated by TGF-beta1 in a Smad- and Sp1-dependent manner
    • Lu N., Carracedo S., Ranta J., Heuchel R., Soininen R., Gullberg D. The human alpha11 integrin promoter drives fibroblast-restricted expression in vivo and is regulated by TGF-beta1 in a Smad- and Sp1-dependent manner. Matrix Biol 2010, 29(3):166-176.
    • (2010) Matrix Biol , vol.29 , Issue.3 , pp. 166-176
    • Lu, N.1    Carracedo, S.2    Ranta, J.3    Heuchel, R.4    Soininen, R.5    Gullberg, D.6
  • 28
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
    • Irizarry R.A., Ladd-Acosta C., Wen B., Wu Z., Montano C., Onyango P., et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009, 41(2):178-186.
    • (2009) Nat Genet , vol.41 , Issue.2 , pp. 178-186
    • Irizarry, R.A.1    Ladd-Acosta, C.2    Wen, B.3    Wu, Z.4    Montano, C.5    Onyango, P.6
  • 29
    • 76249090741 scopus 로고    scopus 로고
    • Nucleosome deposition and DNA methylation at coding region boundaries
    • Choi J.K., Bae J.B., Lyu J., Kim T.Y., Kim Y.J. Nucleosome deposition and DNA methylation at coding region boundaries. Genome Biol 2009, 10(9):R89.
    • (2009) Genome Biol , vol.10 , Issue.9 , pp. R89
    • Choi, J.K.1    Bae, J.B.2    Lyu, J.3    Kim, T.Y.4    Kim, Y.J.5
  • 30
    • 79958754527 scopus 로고    scopus 로고
    • Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
    • Sandoval J., Heyn H., Moran S., Serra-Musach J., Pujana M.A., Bibikova M., et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics 2011, 6(6):692-702.
    • (2011) Epigenetics , vol.6 , Issue.6 , pp. 692-702
    • Sandoval, J.1    Heyn, H.2    Moran, S.3    Serra-Musach, J.4    Pujana, M.A.5    Bibikova, M.6
  • 31
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: islands, start sites, gene bodies and beyond
    • Jones P.A. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 2012, 13(7):484-492.
    • (2012) Nat Rev Genet , vol.13 , Issue.7 , pp. 484-492
    • Jones, P.A.1
  • 35
    • 77955053847 scopus 로고    scopus 로고
    • Hox genes and regional patterning of the vertebrate body plan
    • Mallo M., Wellik D.M., Deschamps J. Hox genes and regional patterning of the vertebrate body plan. Dev Biol 2010, 344(1):7-15.
    • (2010) Dev Biol , vol.344 , Issue.1 , pp. 7-15
    • Mallo, M.1    Wellik, D.M.2    Deschamps, J.3
  • 37
    • 84869046236 scopus 로고    scopus 로고
    • Methylation alterations of WT1 and homeobox genes in inflamed muscle biopsy samples from patients with untreated juvenile dermatomyositis suggest self-renewal capacity
    • Wang M., Xie H., Shrestha S., Sredni S., Morgan G.A., Pachman L.M. Methylation alterations of WT1 and homeobox genes in inflamed muscle biopsy samples from patients with untreated juvenile dermatomyositis suggest self-renewal capacity. Arthritis Rheum 2012, 64(10):3478-3485.
    • (2012) Arthritis Rheum , vol.64 , Issue.10 , pp. 3478-3485
    • Wang, M.1    Xie, H.2    Shrestha, S.3    Sredni, S.4    Morgan, G.A.5    Pachman, L.M.6
  • 39
    • 84924911763 scopus 로고    scopus 로고
    • Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs
    • Dijksterhuis J.P., Baljinnyam B., Stanger K., Sercan H.O., Ji Y., Andres O., et al. Systematic mapping of WNT-FZD protein interactions reveals functional selectivity by distinct WNT-FZD pairs. J Biol Chem 2015, 290(11):6789-6798.
    • (2015) J Biol Chem , vol.290 , Issue.11 , pp. 6789-6798
    • Dijksterhuis, J.P.1    Baljinnyam, B.2    Stanger, K.3    Sercan, H.O.4    Ji, Y.5    Andres, O.6
  • 40
    • 53849125461 scopus 로고    scopus 로고
    • Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis
    • Corr M. Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis. Nat Clin Pract Rheumatol 2008, 4(10):550-556.
    • (2008) Nat Clin Pract Rheumatol , vol.4 , Issue.10 , pp. 550-556
    • Corr, M.1
  • 41
    • 84862545919 scopus 로고    scopus 로고
    • Insights on biology and pathology of HIF-1alpha/-2alpha, TGFbeta/BMP, Wnt/beta-catenin, and NF-kappaB pathways in osteoarthritis
    • Wu L., Huang X., Li L., Huang H., Xu R., Luyten W. Insights on biology and pathology of HIF-1alpha/-2alpha, TGFbeta/BMP, Wnt/beta-catenin, and NF-kappaB pathways in osteoarthritis. Curr Pharm Des 2012, 18(22):3293-3312.
    • (2012) Curr Pharm Des , vol.18 , Issue.22 , pp. 3293-3312
    • Wu, L.1    Huang, X.2    Li, L.3    Huang, H.4    Xu, R.5    Luyten, W.6
  • 42
    • 77951073232 scopus 로고    scopus 로고
    • To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy
    • Blom A.B., van Lent P.L., van der Kraan P.M., van den Berg W.B. To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy. Curr Drug Targets 2010, 11(5):620-629.
    • (2010) Curr Drug Targets , vol.11 , Issue.5 , pp. 620-629
    • Blom, A.B.1    van Lent, P.L.2    van der Kraan, P.M.3    van den Berg, W.B.4
  • 43
    • 17844372752 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis
    • Day T.F., Guo X., Garrett-Beal L., Yang Y. Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis. Dev Cell 2005, 8(5):739-750.
    • (2005) Dev Cell , vol.8 , Issue.5 , pp. 739-750
    • Day, T.F.1    Guo, X.2    Garrett-Beal, L.3    Yang, Y.4
  • 44
    • 84924632183 scopus 로고    scopus 로고
    • Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation
    • Narcisi R., Cleary M.A., Brama P.A., Hoogduijn M.J., Tuysuz N., ten Berge D., et al. Long-term expansion, enhanced chondrogenic potential, and suppression of endochondral ossification of adult human MSCs via WNT signaling modulation. Stem Cell Rep 2015, 4(3):459-472.
    • (2015) Stem Cell Rep , vol.4 , Issue.3 , pp. 459-472
    • Narcisi, R.1    Cleary, M.A.2    Brama, P.A.3    Hoogduijn, M.J.4    Tuysuz, N.5    ten Berge, D.6
  • 45
    • 62949120743 scopus 로고    scopus 로고
    • Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis
    • Koelling S., Kruegel J., Irmer M., Path J.R., Sadowski B., Miro X., et al. Migratory chondrogenic progenitor cells from repair tissue during the later stages of human osteoarthritis. Cell Stem Cell 2009, 4(4):324-335.
    • (2009) Cell Stem Cell , vol.4 , Issue.4 , pp. 324-335
    • Koelling, S.1    Kruegel, J.2    Irmer, M.3    Path, J.R.4    Sadowski, B.5    Miro, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.