Class i histone deacetylase inhibition modulates metalloproteinase expression and blocks cytokine-induced cartilage degradation

Arthritis and Rheumatism

Volumn 65, Issue 7, 2013, Pages 1822-1830

  Culley, Kirsty L ^a   Hui, Wang ^b   Barter, Matt J ^b   Davidson, Rose K ^a   Swingler, Tracey E ^a   Destrument, Auriane P M ^b   Scott, Jenny L ^b   Donell, Simon T ^c   Fenwick, Steve ^d,e   Rowan, Andrew D ^b   Young, David A ^b   Clark, Ian M ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NORFOLK AND NORWICH UNIVERSITY HOSPITAL   (United Kingdom)

^d Smith and Nephew Research Centre   (United Kingdom)

^e HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; COLLAGENASE 3; CYTOKINE; ENTINOSTAT; HISTONE DEACETYLASE 1; METALLOPROTEINASE; SMALL INTERFERING RNA; TRICHOSTATIN A; VALPROIC ACID;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARTILAGE CELL; CARTILAGE DEGENERATION; CHONDROLYSIS; CHONDROPROTECTION; CHONDROSARCOMA; CONTROLLED STUDY; DRUG ACTIVITY; ENZYME INHIBITION; EXPLANT; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KNEE MENISCUS; MOUSE; NONHUMAN; NOSE CARTILAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; QUANTITATIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; BENZAMIDES; CATTLE; CELL LINE, TUMOR; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; HISTONE DEACETYLASE INHIBITORS; HISTONES; HUMANS; HYDROXAMIC ACIDS; METALLOPROTEASES; MICE; MICE, INBRED C57BL; NASAL CARTILAGES; OSTEOARTHRITIS, KNEE; PYRIDINES; RNA, SMALL INTERFERING; TUBULIN;

EID: 84879851334     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37965     Document Type: Article

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