-
1
-
-
0025829522
-
Erythropoietin
-
Erslev AJ. Erythropoietin. N Engl J Med. 1991;324(19):1339-1344.
-
(1991)
N Engl J Med
, vol.324
, Issue.19
, pp. 1339-1344
-
-
Erslev, A.J.1
-
2
-
-
0025931724
-
Erythropoietin 1991 - An overview
-
Eschbach JW. Erythropoietin 1991 - an overview. Am J Kidney Dis. 1991;18(4 suppl 1):3-9.
-
(1991)
Am J Kidney Dis
, vol.18
, Issue.4
, pp. 3-9
-
-
Eschbach, J.W.1
-
3
-
-
48149088154
-
The effect of altitude on dosing and response to erythropoietin in ESRD
-
Brookhart MA, et al. The effect of altitude on dosing and response to erythropoietin in ESRD. J Am Soc Nephrol. 2008;19(7):1389-1395.
-
(2008)
J Am Soc Nephrol
, vol.19
, Issue.7
, pp. 1389-1395
-
-
Brookhart, M.A.1
-
4
-
-
0023199353
-
Erythropoietin-hematocrit feedback circuit in the anemia of end-stage renal disease
-
Walle AJ, Wong GY, Clemons GK, Garcia JF, Niedermayer W. Erythropoietin-hematocrit feedback circuit in the anemia of end-stage renal disease. Kidney Int. 1987;31(5):1205-1209.
-
(1987)
Kidney Int
, vol.31
, Issue.5
, pp. 1205-1209
-
-
Walle, A.J.1
Wong, G.Y.2
Clemons, G.K.3
Garcia, J.F.4
Niedermayer, W.5
-
5
-
-
0024213759
-
Relation of serum erythropoietin levels to renal excretory function: Evidence for lowered set point for erythropoietin production in chronic renal failure
-
Chandra M, Clemons GK, McVicar MI. Relation of serum erythropoietin levels to renal excretory function: evidence for lowered set point for erythropoietin production in chronic renal failure. J Pediatr. 1988;113(6):1015-1021.
-
(1988)
J Pediatr
, vol.113
, Issue.6
, pp. 1015-1021
-
-
Chandra, M.1
Clemons, G.K.2
McVicar, M.I.3
-
6
-
-
0018889403
-
Renal and extrarenal erythropoietin production in anaemic rats
-
Erslev AJ, Caro J, Kansu E, Silver R. Renal and extrarenal erythropoietin production in anaemic rats. Br J Haematol. 1980;45(1):65-72.
-
(1980)
Br J Haematol
, vol.45
, Issue.1
, pp. 65-72
-
-
Erslev, A.J.1
Caro, J.2
Kansu, E.3
Silver, R.4
-
7
-
-
78649876180
-
Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD
-
Bernhardt WM, et al. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. J Am Soc Nephrol. 2010;21(12):2151-2156.
-
(2010)
J Am Soc Nephrol
, vol.21
, Issue.12
, pp. 2151-2156
-
-
Bernhardt, W.M.1
-
8
-
-
0027367661
-
Identification of the renal erythropoietin-producing cells using transgenic mice
-
Maxwell PH, et al. Identification of the renal erythropoietin-producing cells using transgenic mice. Kidney Int. 1993;44(5):1149-1162.
-
(1993)
Kidney Int
, vol.44
, Issue.5
, pp. 1149-1162
-
-
Maxwell, P.H.1
-
9
-
-
0027410945
-
Co-localization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin
-
Bachmann S, Le Hir M, Eckardt KU. Co-localization of erythropoietin mRNA and ecto-5'-nucleotidase immunoreactivity in peritubular cells of rat renal cortex indicates that fibroblasts produce erythropoietin. J Histochem Cytochem. 1993;41(3):335-341.
-
(1993)
J Histochem Cytochem
, vol.41
, Issue.3
, pp. 335-341
-
-
Bachmann, S.1
Le Hir, M.2
Eckardt, K.U.3
-
10
-
-
46749127450
-
Repression via the GATA box is essential for tissue-specific erythropoietin gene expression
-
Obara N, Suzuki N, Kim K, Nagasawa T, Imagawa S, Yamamoto M. Repression via the GATA box is essential for tissue-specific erythropoietin gene expression. Blood. 2008;111(10):5223-5232.
-
(2008)
Blood
, vol.111
, Issue.10
, pp. 5223-5232
-
-
Obara, N.1
Suzuki, N.2
Kim, K.3
Nagasawa, T.4
Imagawa, S.5
Yamamoto, M.6
-
11
-
-
80053394522
-
Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice
-
Asada N, et al. Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest. 2011;121(10):3981-3990.
-
(2011)
J Clin Invest
, vol.121
, Issue.10
, pp. 3981-3990
-
-
Asada, N.1
-
12
-
-
84881115491
-
Renal CD133(+)/CD73(+) progenitors produce erythropoietin under hypoxia and prolyl hydroxylase inhibition
-
Bussolati B, Lauritano C, Moggio A, Collino F, Mazzone M, Camussi G. Renal CD133(+)/CD73(+) progenitors produce erythropoietin under hypoxia and prolyl hydroxylase inhibition. J Am Soc Nephrol. 2013;24(8):1234-1241.
-
(2013)
J Am Soc Nephrol
, vol.24
, Issue.8
, pp. 1234-1241
-
-
Bussolati, B.1
Lauritano, C.2
Moggio, A.3
Collino, F.4
Mazzone, M.5
Camussi, G.6
-
13
-
-
84890195204
-
A mouse model of adult-onset anaemia due to erythropoietin deficiency
-
Yamazaki S, et al. A mouse model of adult-onset anaemia due to erythropoietin deficiency. Nat Commun. 2013;4:1950.
-
(2013)
Nat Commun
, vol.4
, pp. 1950
-
-
Yamazaki, S.1
-
14
-
-
84885060233
-
Plasticity of renal erythropoietin-producing cells governs fibrosis
-
Souma T, et al. Plasticity of renal erythropoietin-producing cells governs fibrosis. J Am Soc Nephrol. 2013;24(10):1599-1616.
-
(2013)
J Am Soc Nephrol
, vol.24
, Issue.10
, pp. 1599-1616
-
-
Souma, T.1
-
15
-
-
80052568370
-
Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages
-
Suzuki N, et al. Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages. Mol Cell Biol. 2011;31(18):3896-3905.
-
(2011)
Mol Cell Biol
, vol.31
, Issue.18
, pp. 3896-3905
-
-
Suzuki, N.1
-
16
-
-
84897451173
-
A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression
-
Storti F, et al. A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression. Haematologica. 2014;99(4):e45-e48.
-
(2014)
Haematologica
, vol.99
, Issue.4
, pp. e45-e48
-
-
Storti, F.1
-
17
-
-
0033957513
-
DNA methylation represses the expression of the human erythropoietin gene by two different mechanisms
-
Yin H, Blanchard KL. DNA methylation represses the expression of the human erythropoietin gene by two different mechanisms. Blood. 2000;95(1):111-119.
-
(2000)
Blood
, vol.95
, Issue.1
, pp. 111-119
-
-
Yin, H.1
Blanchard, K.L.2
-
18
-
-
84943808252
-
Methylation impact analysis of erythropoietin (EPO) gene to hypoxia inducible factor-1alpha (HIF-1α) activity
-
Dewi FR, Fatchiyah F. Methylation impact analysis of erythropoietin (EPO) gene to hypoxia inducible factor-1alpha (HIF-1α) activity. Bioinformation. 2013;9(15):782-787.
-
(2013)
Bioinformation
, vol.9
, Issue.15
, pp. 782-787
-
-
Dewi, F.R.1
Fatchiyah, F.2
-
19
-
-
16644380412
-
Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site
-
Rossler J, et al. Hypoxia-induced erythropoietin expression in human neuroblastoma requires a methylation free HIF-1 binding site. J Cell Biochem. 2004;93(1):153-161.
-
(2004)
J Cell Biochem
, vol.93
, Issue.1
, pp. 153-161
-
-
Rossler, J.1
-
20
-
-
79960031964
-
Epigenetic silencing of erythropoietin in human cancers
-
Steinmann K, Richter AM, Dammann RH. Epigenetic silencing of erythropoietin in human cancers. Genes Cancer. 2011;2(1):65-73.
-
(2011)
Genes Cancer
, vol.2
, Issue.1
, pp. 65-73
-
-
Steinmann, K.1
Richter, A.M.2
Dammann, R.H.3
-
21
-
-
84902179695
-
Cellular and molecular mechanisms in kidney fibrosis
-
Duffield JS. Cellular and molecular mechanisms in kidney fibrosis. J Clin Invest. 2014;124(6):2299-2306.
-
(2014)
J Clin Invest
, vol.124
, Issue.6
, pp. 2299-2306
-
-
Duffield, J.S.1
-
22
-
-
57149113728
-
Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney
-
Lin SL, Kisseleva T, Brenner DA, Duffield JS. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. Am J Pathol. 2008;173(6):1617-1627.
-
(2008)
Am J Pathol
, vol.173
, Issue.6
, pp. 1617-1627
-
-
Lin, S.L.1
Kisseleva, T.2
Brenner, D.A.3
Duffield, J.S.4
-
23
-
-
73949096744
-
Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis
-
Humphreys BD, et al. Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis. Am J Pathol. 2010;176(1):85-97.
-
(2010)
Am J Pathol
, vol.176
, Issue.1
, pp. 85-97
-
-
Humphreys, B.D.1
-
24
-
-
79951816985
-
Targeting endothelium-pericyte crosstalk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis
-
Lin SL, et al. Targeting endothelium-pericyte crosstalk by inhibiting VEGF receptor signaling attenuates kidney microvascular rarefaction and fibrosis. Am J Pathol. 2011;178(2):911-923.
-
(2011)
Am J Pathol
, vol.178
, Issue.2
, pp. 911-923
-
-
Lin, S.L.1
-
25
-
-
84860645452
-
Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury
-
Schrimpf C, et al. Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury. J Am Soc Nephrol. 2012;23(5):868-883.
-
(2012)
J Am Soc Nephrol
, vol.23
, Issue.5
, pp. 868-883
-
-
Schrimpf, C.1
-
26
-
-
84872420242
-
Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis
-
Chang FC, Chou YH, Chen YT, Lin SL. Novel insights into pericyte-myofibroblast transition and therapeutic targets in renal fibrosis. J Formos Med Assoc. 2012;111(11):589-598.
-
(2012)
J Formos Med Assoc
, vol.111
, Issue.11
, pp. 589-598
-
-
Chang, F.C.1
Chou, Y.H.2
Chen, Y.T.3
Lin, S.L.4
-
27
-
-
84920730709
-
Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis
-
Kramann R, et al. Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis. Cell Stem Cell. 2015;16(1):51-66.
-
(2015)
Cell Stem Cell
, vol.16
, Issue.1
, pp. 51-66
-
-
Kramann, R.1
-
28
-
-
81155131228
-
Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis
-
Chen YT, et al. Platelet-derived growth factor receptor signaling activates pericyte-myofibroblast transition in obstructive and post-ischemic kidney fibrosis. Kidney Int. 2011;80(11):1170-1181.
-
(2011)
Kidney Int
, vol.80
, Issue.11
, pp. 1170-1181
-
-
Chen, Y.T.1
-
29
-
-
84871300122
-
Transforming growth factor beta-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis
-
Wu CF, et al. Transforming growth factor beta-1 stimulates profibrotic epithelial signaling to activate pericyte-myofibroblast transition in obstructive kidney fibrosis. Am J Pathol. 2013;182(1):118-131.
-
(2013)
Am J Pathol
, vol.182
, Issue.1
, pp. 118-131
-
-
Wu, C.F.1
-
30
-
-
84872867267
-
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1
-
Ren S, et al. LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1. Proc Natl Acad Sci U S A. 2013;110(4):1440-1445.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.4
, pp. 1440-1445
-
-
Ren, S.1
-
31
-
-
77749319814
-
Serum amyloid P inhibits fibrosis through FcγR-dependent monocyte-macrophage regulation in vivo
-
Castano AP, et al. Serum amyloid P inhibits fibrosis through FcγR-dependent monocyte-macrophage regulation in vivo. Sci Transl Med. 2009;1(5):5ra13.
-
(2009)
Sci Transl Med
, vol.1
, Issue.5
, pp. 5ra13
-
-
Castano, A.P.1
-
32
-
-
77952116121
-
Methylation determines fibroblast activation and fibrogenesis in the kidney
-
Bechtel W, et al. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010;16(5):544-550.
-
(2010)
Nat Med
, vol.16
, Issue.5
, pp. 544-550
-
-
Bechtel, W.1
-
33
-
-
33847796951
-
Acute postnatal ablation of Hif-2α results in anemia
-
Gruber M, Hu CJ, Johnson RS, Brown EJ, Keith B, Simon MC. Acute postnatal ablation of Hif-2α results in anemia. Proc Natl Acad Sci U S A. 2007;104(7):2301-2306.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.7
, pp. 2301-2306
-
-
Gruber, M.1
Hu, C.J.2
Johnson, R.S.3
Brown, E.J.4
Keith, B.5
Simon, M.C.6
-
34
-
-
77958177671
-
Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia
-
Kapitsinou PP, et al. Hepatic HIF-2 regulates erythropoietic responses to hypoxia in renal anemia. Blood. 2010;116(16):3039-3048.
-
(2010)
Blood
, vol.116
, Issue.16
, pp. 3039-3048
-
-
Kapitsinou, P.P.1
-
35
-
-
75749150800
-
Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization
-
Paliege A, et al. Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization. Kidney Int. 2010;77(4):312-318.
-
(2010)
Kidney Int
, vol.77
, Issue.4
, pp. 312-318
-
-
Paliege, A.1
-
36
-
-
84863337757
-
Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells
-
Tsai H-C, et al. Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. Cancer Cell. 2012;21(3):430-446.
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 430-446
-
-
Tsai, H.-C.1
-
37
-
-
84859554235
-
In epigenetic therapy, less is more
-
Shen H, Laird PW. In epigenetic therapy, less is more. Cell Stem Cell. 2012;10(4):353-354.
-
(2012)
Cell Stem Cell
, vol.10
, Issue.4
, pp. 353-354
-
-
Shen, H.1
Laird, P.W.2
-
38
-
-
10744233452
-
Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies
-
Issa J-PJ, et al. Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies. Blood. 2004;103(5):1635-1640.
-
(2004)
Blood
, vol.103
, Issue.5
, pp. 1635-1640
-
-
J-Pj, I.1
-
39
-
-
0030964765
-
Erythropoietin in the pathogenesis and treatment of the anemia of chronic renal failure
-
Erslev AJ, Besarab A. Erythropoietin in the pathogenesis and treatment of the anemia of chronic renal failure. Kidney Int. 1997;51(3):622-630.
-
(1997)
Kidney Int
, vol.51
, Issue.3
, pp. 622-630
-
-
Erslev, A.J.1
Besarab, A.2
-
40
-
-
80155151941
-
Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner
-
Chiang CK, Tanaka T, Inagi R, Fujita T, Nangaku M. Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner. Lab Invest. 2011;91(11):1564-1571.
-
(2011)
Lab Invest
, vol.91
, Issue.11
, pp. 1564-1571
-
-
Chiang, C.K.1
Tanaka, T.2
Inagi, R.3
Fujita, T.4
Nangaku, M.5
-
41
-
-
0018894525
-
Improving anemia by hemodialysis: Effect of serum erythropoietin
-
Radtke HW, Frei U, Erbes PM, Schoeppe W, Koch KM. Improving anemia by hemodialysis: effect of serum erythropoietin. Kidney Int. 1980;17(3):382-387.
-
(1980)
Kidney Int
, vol.17
, Issue.3
, pp. 382-387
-
-
Radtke, H.W.1
Frei, U.2
Erbes, P.M.3
Schoeppe, W.4
Koch, K.M.5
-
42
-
-
73849144012
-
The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 α in progression of chronic kidney disease
-
Tanaka T, Nangaku M. The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 α in progression of chronic kidney disease. Curr Opin Nephrol Hypertens. 2010;19(1):43-50.
-
(2010)
Curr Opin Nephrol Hypertens
, vol.19
, Issue.1
, pp. 43-50
-
-
Tanaka, T.1
Nangaku, M.2
-
43
-
-
78651395628
-
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
-
Wang Z, et al. Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells. Kidney Int. 2011;79(3):300-310.
-
(2011)
Kidney Int
, vol.79
, Issue.3
, pp. 300-310
-
-
Wang, Z.1
-
44
-
-
84939872439
-
Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney
-
Pritchett TL, Bader HL, Henderson J, Hsu T. Conditional inactivation of the mouse von Hippel-Lindau tumor suppressor gene results in wide-spread hyperplastic, inflammatory and fibrotic lesions in the kidney. Oncogene. 2015;34(20):2631-2639.
-
(2015)
Oncogene
, vol.34
, Issue.20
, pp. 2631-2639
-
-
Pritchett, T.L.1
Bader, H.L.2
Henderson, J.3
Hsu, T.4
-
45
-
-
84923861810
-
Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury
-
Chen YT, et al. Lineage tracing reveals distinctive fates for mesothelial cells and submesothelial fibroblasts during peritoneal injury. J Am Soc Nephrol. 2014;25(12):2847-2858.
-
(2014)
J Am Soc Nephrol
, vol.25
, Issue.12
, pp. 2847-2858
-
-
Chen, Y.T.1
-
46
-
-
64649098703
-
Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model
-
Tamura M, Aizawa R, Hori M, Ozaki H. Progressive renal dysfunction and macrophage infiltration in interstitial fibrosis in an adenine-induced tubulointerstitial nephritis mouse model. Histochem Cell Biol. 2009;131(4):483-490.
-
(2009)
Histochem Cell Biol
, vol.131
, Issue.4
, pp. 483-490
-
-
Tamura, M.1
Aizawa, R.2
Hori, M.3
Ozaki, H.4
|