Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effect

eLife

Volumn 4, Issue DECEMBER2015, 2015, Pages

  Zielinska, Agata P ^a   Holubcova, Zuzana ^a   Blayney, Martyn ^b   Elder, Kay ^b   Schuh, Melina ^a,c  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b Bourn Hall Clinic ^*  (United Kingdom)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANAPHASE; ARTICLE; BIVALENT TWISTING; CELL ADHESION; CELL COUNT; CENTROMERE; CHROMOSOMAL PARAMETERS; CHROMOSOME ARM; CHROMOSOME BIVALENT; CHROMOSOME DAMAGE; COLD TREATMENT; CONFOCAL MICROSCOPY; DEPOLYMERIZATION; FEMALE; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; INTRACYTOPLASMIC SPERM INJECTION; KINETOCHORE MICROTUBULE; KINETOCHORE SPLITTING; MATERNAL AGE; MEIOSIS; MESSENGER RNA SYNTHESIS; OOCYTE; OOCYTE DEVELOPMENT; ROTATION; SISTER CHROMATID; ANEUPLOIDY; CHROMOSOME SEGREGATION; KINETOCHORE; METABOLISM; PHYSIOLOGY;

ANEUPLOIDY; CHROMOSOME SEGREGATION; HUMANS; KINETOCHORES; MATERNAL AGE; MEIOSIS; OOCYTES;

EID: 84956890317     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11389     Document Type: Article

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