Reduced ability to recover from spindle disruption and loss of kinetochore spindle assembly checkpoint proteins in oocytes from aged mice

Cell Cycle

Volumn 13, Issue 12, 2014, Pages 1938-1947

  Yun, Yan ^a   Holt, Janet E ^a   Lane, Simon I R ^a,b   McLaughlin, Eileen A ^c   Merriman, Julie A ^a,b   Jones, Keith T ^a,b  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^c UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Aging; Aneuploidy; Cell cycle; Error correction; Meiosis; Oocyte; Spindle assembly checkpoint

Indexed keywords

AURORA C KINASE; N [4 [6 METHOXY 7 (3 MORPHOLINOPROPOXY) 4 QUINAZOLINYLAMINO]PHENYL]BENZAMIDE; NOCODAZOLE; PROTEIN MAD2; CELL CYCLE PROTEIN; MAD2L1 PROTEIN, MOUSE; SGOL2 PROTEIN, MOUSE;

AGED; ANEUPLOIDY; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL DISRUPTION; CENTROMERE; CONTROLLED STUDY; DEPOLYMERIZATION; ENZYME PHOSPHORYLATION; FEMALE; KINETOCHORE MICROTUBULE; M PHASE CELL CYCLE CHECKPOINT; MATERNAL AGE; MEIOTIC SPINDLE; MOUSE; NONHUMAN; OOCYTE; OOCYTE MATURATION; SISTER CHROMATID; AGING; ANIMAL; C57BL MOUSE; CHROMOSOME SEGREGATION; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SPECIES DIFFERENCE; SPINDLE APPARATUS;

AGING; ANEUPLOIDY; ANIMALS; AURORA KINASE C; CELL CYCLE PROTEINS; CHROMOSOME SEGREGATION; FEMALE; KINETOCHORES; M PHASE CELL CYCLE CHECKPOINTS; MAD2 PROTEINS; MICE; MICE, INBRED C57BL; NOCODAZOLE; OOCYTES; SPECIES SPECIFICITY; SPINDLE APPARATUS;

EID: 84902496194     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.28897     Document Type: Article

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