-
1
-
-
60049098657
-
Beiträge zur Theorie des Mikroskops und der mikroskopischen Wahrnehmung
-
ABBE, E. (1873). Beiträge zur Theorie des Mikroskops und der mikroskopischen Wahrnehmung. Archiv für Mikroskopische Anatomie 9, 413-468.
-
(1873)
Archiv für Mikroskopische Anatomie
, vol.9
, pp. 413-468
-
-
Abbe, E.1
-
2
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
ARRASATE, M., MITRA, S., SCHWEITZER, E. S., SEGAL, M.R. & FINKBEINER, S. (2004). Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death. Nature 431(7010), 805-810.
-
(2004)
Nature
, vol.431
, Issue.7010
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
3
-
-
85017268070
-
Huntington disease
-
BATES, G. P., DORSEY, R., GUSELLA, J. F., HAYDEN, M. R., KAY, C., LEAVITT, B. R., NANCE, M., ROSS, C. A., SCAHILL, R. I., WETZEL, R., WILD, E.J. & TABRIZI, S. J. (2015). Huntington disease. Nature Reviews Disease Primers, article number 15005. doi: 10.1038/nrdp.2015.5.
-
(2015)
Nature Reviews Disease Primers
-
-
Bates, G.P.1
Dorsey, R.2
Gusella, J.F.3
Hayden, M.R.4
Kay, C.5
Leavitt, B.R.6
Nance, M.7
Ross, C.A.8
Scahill, R.I.9
Wetzel, R.10
Wild, E.J.11
Tabrizi, S.J.12
-
4
-
-
84856653724
-
Nanoscopy in a living mouse brain
-
BERNING, S., WILLIG, K. I., STEFFENS, H., DIBAJ, P. & HELL, S.W. (2012). Nanoscopy in a living mouse brain. Science 335(6068), 551.
-
(2012)
Science
, vol.335
, Issue.6068
, pp. 551
-
-
Berning, S.1
Willig, K.I.2
Steffens, H.3
Dibaj, P.4
Hell, S.W.5
-
5
-
-
56149118370
-
Super-resolution imaging in live caulobacter crescentus cells using photoswitchable EYFP
-
BITEEN, J. S., THOMPSON, M. A., TSELENTIS, N. K., BOWMAN, G. R., SHAPIRO, L. & MOERNER, W. E. (2008). Super-resolution imaging in live Caulobacter crescentus cells using photoswitchable EYFP. Nature Methods 5, 947-949.
-
(2008)
Nature Methods
, vol.5
, pp. 947-949
-
-
Biteen, J.S.1
Thompson, M.A.2
Tselentis, N.K.3
Bowman, G.R.4
Shapiro, L.5
Moerner, W.E.6
-
6
-
-
38149030094
-
Determination of particle number and brightness using a laser scanning confocal microscope operating in the analog mode
-
DALAL, R. B., DIGMAN, M. A., HORWITZ, A. F., VETRI, V. & GRATTON, E. (2008). Determination of particle number and brightness using a laser scanning confocal microscope operating in the analog mode. Microscopy Research and Technique 71(1), 69-81.
-
(2008)
Microscopy Research and Technique
, vol.71
, Issue.1
, pp. 69-81
-
-
Dalal, R.B.1
Digman, M.A.2
Horwitz, A.F.3
Vetri, V.4
Gratton, E.5
-
7
-
-
0030832226
-
On/off blinking and switching behaviour of single molecules of green fluorescent protein
-
DICKSON, R. M., CUBITT, A. B., TSIEN, R.Y. & MOERNER, W. E. (1997). On/off blinking and switching behaviour of single molecules of green fluorescent protein. Nature 388(6640), 355-358.
-
(1997)
Nature
, vol.388
, Issue.6640
, pp. 355-358
-
-
Dickson, R.M.1
Cubitt, A.B.2
Tsien, R.Y.3
Moerner, W.E.4
-
8
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DIFIGLIA, M., SAPP, E., CHASE, K. O., DAVIES, S.W., BATES, G.P., VONSATTEL, J.P. & ARONIN, N. (1997). Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277(5334), 1990-1993.
-
(1997)
Science
, vol.277
, Issue.5334
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
9
-
-
44049105523
-
Mapping the number of molecules and brightness in the laser scanning microscope
-
DIGMAN, M. A., DALAL, R., HORWITZ, A.F. & GRATTON, E. (2008). Mapping the number of molecules and brightness in the laser scanning microscope. Biophysical Journal 94(6), 2320-2332.
-
(2008)
Biophysical Journal
, vol.94
, Issue.6
, pp. 2320-2332
-
-
Digman, M.A.1
Dalal, R.2
Horwitz, A.F.3
Gratton, E.4
-
10
-
-
80052501613
-
Subdiffraction imaging of huntingtin protein aggregates by fluorescence blink-microscopy and atomic force microscopy
-
DUIM, W. C., CHEN, B., FRYDMAN, J. & MOERNER, W. E. (2011). Subdiffraction imaging of huntingtin protein aggregates by fluorescence blink-microscopy and atomic force microscopy. ChemPhysChem 12(13), 2387-2390.
-
(2011)
ChemPhysChem
, vol.12
, Issue.13
, pp. 2387-2390
-
-
Duim, W.C.1
Chen, B.2
Frydman, J.3
Moerner, W.E.4
-
11
-
-
84919702871
-
Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregates
-
DUIM, W. C., JIANG, Y., SHEN, K., FRYDMAN, J. & MOERNER, W.E. (2014). Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregates. ACS Chemical Biology 9(12), 2767-2778.
-
(2014)
ACS Chemical Biology
, vol.9
, Issue.12
, pp. 2767-2778
-
-
Duim, W.C.1
Jiang, Y.2
Shen, K.3
Frydman, J.4
Moerner, W.E.5
-
12
-
-
0028460042
-
Breaking the diffraction resolution limit by stimulated-emission - stimulated-emissiondepletion fluorescence microscopy
-
HELL, S.W. & WICHMANN, J. (1994). Breaking the diffraction resolution limit by stimulated-emission - stimulated-emissiondepletion fluorescence microscopy. Optics Letters 19(11), 780-782.
-
(1994)
Optics Letters
, vol.19
, Issue.11
, pp. 780-782
-
-
Hell, S.W.1
Wichmann, J.2
-
13
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
HUNTINGTON'S DISEASE COLLABORATIVE RESEARCH GROUP. (1993). A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72(6), 971-983.
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 971-983
-
-
-
14
-
-
84893649786
-
D-polyglutamine amyloid recruits l-polyglutamine monomers and kills cells
-
KAR, K., ARDUINI, I., DROMBOSKY, K.W., VAN DER WEL, P.C.A. & WETZEL, R. (2014). d-Polyglutamine amyloid recruits l-polyglutamine monomers and kills cells. Journal of Molecular Biology 426(4), 816-829.
-
(2014)
Journal of Molecular Biology
, vol.426
, Issue.4
, pp. 816-829
-
-
Kar, K.1
Arduini, I.2
Drombosky, K.W.3
Van Der-Wel, P.C.A.4
Wetzel, R.5
-
15
-
-
0032607671
-
Subdiffraction resolution in farfield fluorescence microscopy
-
KLAR, T.A. & HELL, S.W. (1999). Subdiffraction resolution in farfield fluorescence microscopy. Optics Letters 24(14), 954-956.
-
(1999)
Optics Letters
, vol.24
, Issue.14
, pp. 954-956
-
-
Klar, T.A.1
Hell, S.W.2
-
16
-
-
84898623416
-
Biophysical underpinnings of the repeat length dependence of polyglutamine amyloid formation
-
LANDRUM, E. & WETZEL, R. (2014). Biophysical underpinnings of the repeat length dependence of polyglutamine amyloid formation. Journal of Biological Chemistry 289(15), 10254-10260.
-
(2014)
Journal of Biological Chemistry
, vol.289
, Issue.15
, pp. 10254-10260
-
-
Landrum, E.1
Wetzel, R.2
-
17
-
-
77951988103
-
Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo
-
LEGLEITER, J., MITCHELL, E., LOTZ, G. P., SAPP, E., NG, C., DIFIGLIA, M., THOMPSON, L.M. & MUCHOWSKI, P. J. (2010). Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo. Journal of Biological Chemistry 285(19), 14777-14790.
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.19
, pp. 14777-14790
-
-
Legleiter, J.1
Mitchell, E.2
Lotz, G.P.3
Sapp, E.4
Ng, C.5
Difiglia, M.6
Thompson, L.M.7
Muchowski, P.J.8
-
18
-
-
0001195918
-
On the theory of optical images, with special reference to the microscope
-
LORD RAYLEIGH. (1896). On the theory of optical images, with special reference to the microscope. Philosophical Magazine 5(42), 167-195.
-
(1896)
Philosophical Magazine
, vol.5
, Issue.42
, pp. 167-195
-
-
-
19
-
-
0030866150
-
Those blinking molecules
-
MOERNER, W. E. (1997). Those blinking molecules. Science 277(5329), 1059-1060.
-
(1997)
Science
, vol.277
, Issue.5329
, pp. 1059-1060
-
-
Moerner, W.E.1
-
20
-
-
34547878369
-
New directions in single-molecule imaging and analysis
-
MOERNER, W. E. (2007). New directions in single-molecule imaging and analysis. Proceedings of the National Academy of Sciences 104(31), 12596-12602.
-
(2007)
Proceedings of the National Academy of Sciences
, vol.104
, Issue.31
, pp. 12596-12602
-
-
Moerner, W.E.1
-
22
-
-
77953567262
-
A two-step path to inclusion formation of huntingtin peptides revealed by number and brightness analysis
-
OSSATO, G., DIGMAN, M. A., AIKEN, C., LUKACSOVICH, T., MARSH, J.L. & GRATTON, E. (2010). A two-step path to inclusion formation of huntingtin peptides revealed by number and brightness analysis. Biophysical Journal 98(12), 3078-3085.
-
(2010)
Biophysical Journal
, vol.98
, Issue.12
, pp. 3078-3085
-
-
Ossato, G.1
Digman, M.A.2
Aiken, C.3
Lukacsovich, T.4
Marsh, J.L.5
Gratton, E.6
-
23
-
-
84862701723
-
Fibrillar α-synuclein and huntingtin exon 1 assemblies are toxic to the cells
-
PIERI, L., MADIONA, K., BOUSSET, L. & MELKI, R. (2012). Fibrillar α-synuclein and huntingtin Exon 1 assemblies are toxic to the cells. Biophysical Journal 102(12), 2894-2905.
-
(2012)
Biophysical Journal
, vol.102
, Issue.12
, pp. 2894-2905
-
-
Pieri, L.1
Madiona, K.2
Bousset, L.3
Melki, R.4
-
24
-
-
0037174879
-
Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization
-
POIRIER, M. A., LI, H., MACOSKO, J., CAI, S., AMZEL, M. & ROSS, C.A. (2002). Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization. Journal of Biological Chemistry 277(43), 41032-41037.
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.43
, pp. 41032-41037
-
-
Poirier, M.A.1
Li, H.2
MacOsko, J.3
Cai, S.4
Amzel, M.5
Ross, C.A.6
-
25
-
-
0035818579
-
Specificity in intracellular protein aggregation and inclusion body formation
-
RAJAN, R. S., ILLING, M. E., BENCE, N.F. & KOPITO, R. R. (2001). Specificity in intracellular protein aggregation and inclusion body formation. Proceedings of the National Academy of Sciences 98(23), 13060-13065.
-
(2001)
Proceedings of the National Academy of Sciences
, vol.98
, Issue.23
, pp. 13060-13065
-
-
Rajan, R.S.1
Illing, M.E.2
Bence, N.F.3
Kopito, R.R.4
-
26
-
-
78650031174
-
Huntington's disease: From molecular pathogenesis to clinical treatment
-
ROSS, C.A. & TABRIZI, S. J. (2011). Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurology 10(1), 83-98.
-
(2011)
Lancet Neurology
, vol.10
, Issue.1
, pp. 83-98
-
-
Ross, C.A.1
Tabrizi, S.J.2
-
28
-
-
84885862934
-
Super-resolution fluorescence imaging with single molecules
-
SAHL, S. J. & MOERNER, W. E. (2013). Super-resolution fluorescence imaging with single molecules. Current Opinion in Structural Biology 23(5), 778-787.
-
(2013)
Current Opinion in Structural Biology
, vol.23
, Issue.5
, pp. 778-787
-
-
Sahl, S.J.1
Moerner, W.E.2
-
29
-
-
84870839496
-
Cellular inclusion bodies of mutant huntingtin exon 1 obscure small fibrillar aggregate species
-
SAHL, S. J., WEISS, L.E., DUIM, W.C., FRYDMAN, J. & MOERNER, W.E. (2012). Cellular inclusion bodies of mutant huntingtin exon 1 obscure small fibrillar aggregate species. Scientific Reports 2, 895.
-
(2012)
Scientific Reports
, vol.2
, pp. 895
-
-
Sahl, S.J.1
Weiss, L.E.2
Duim, W.C.3
Frydman, J.4
Moerner, W.E.5
-
30
-
-
84903214409
-
Aggregation behavior of chemically synthesized, full-length huntingtin exon1
-
SAHOO, B., SINGER, D., KODALI, R., ZUCHNER, T. & WETZEL, R. (2014). Aggregation behavior of chemically synthesized, full-length huntingtin Exon1. Biochemistry 53(24), 3897-3907.
-
(2014)
Biochemistry
, vol.53
, Issue.24
, pp. 3897-3907
-
-
Sahoo, B.1
Singer, D.2
Kodali, R.3
Zuchner, T.4
Wetzel, R.5
-
31
-
-
84873463075
-
Aberrant splicing of HTT generates the pathogenic exon 1 protein in huntington disease
-
SATHASIVAM, K., NEUEDER, A., GIPSON, T. A., LANDLES, C., BENJAMIN, A. C., BONDULICH, M. K., SMITH, D. L., FAULL, R. L. M., ROOS, R. A. C., HOWLAND, D., DETLOFF, P. J., HOUSMAN, D.E. & BATES, G.P. (2013). Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease. Proceedings of the National Academy of Sciences 110(6), 2366-2370.
-
(2013)
Proceedings of the National Academy of Sciences
, vol.110
, Issue.6
, pp. 2366-2370
-
-
Sathasivam, K.1
Neueder, A.2
Gipson, T.A.3
Landles, C.4
Benjamin, A.C.5
Bondulich, M.K.6
Smith, D.L.7
Faull, R.L.M.8
Roos, R.A.C.9
Howland, D.10
Detloff, P.J.11
Housman, D.E.12
Bates, G.P.13
-
32
-
-
0033551063
-
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington's disease pathology
-
SCHERZINGER, E., SITTLER, A., SCHWEIGER, K., HEISER, V., LURZ, R., HASENBANK, R., BATES, G. P., LEHRACH, H. & WANKER, E.E. (1999). Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology. Proceedings of the National Academy of Sciences 96(8), 4604-4609.
-
(1999)
Proceedings of the National Academy of Sciences
, vol.96
, Issue.8
, pp. 4604-4609
-
-
Scherzinger, E.1
Sittler, A.2
Schweiger, K.3
Heiser, V.4
Lurz, R.5
Hasenbank, R.6
Bates, G.P.7
Lehrach, H.8
Wanker, E.E.9
-
33
-
-
84874237482
-
Exogenous delivery of chaperonin subunit fragment apicct1 modulates mutant huntingtin cellular phenotypes
-
SONTAG, E.M., JOACHIMIAK, L.A., TAN, Z., TOMLINSON, A., HOUSMAN, D. E., GLABE, C.G., POTKIN, S.G., FRYDMAN, J. & THOMPSON, L.M. (2013). Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes. Proceedings of the National Academy of Sciences 110(8), 3077-3082.
-
(2013)
Proceedings of the National Academy of Sciences
, vol.110
, Issue.8
, pp. 3077-3082
-
-
Sontag, E.M.1
Joachimiak, L.A.2
Tan, Z.3
Tomlinson, A.4
Housman, D.E.5
Glabe, C.G.6
Potkin, S.G.7
Frydman, J.8
Thompson, L.M.9
-
34
-
-
64049119303
-
Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism
-
THAKUR, A. K., JAYARAMAN, M., MISHRA, R., THAKUR, M., CHELLGREN, V. M., L BYEON, I.-J., ANJUM, D. H., KODALI, R., CREAMER, T.P., CONWAY, J.F., M GRONENBORN, A. & WETZEL, R. (2009). Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nature Structural and Molecular Biology 16(4), 380-389.
-
(2009)
Nature Structural and Molecular Biology
, vol.16
, Issue.4
, pp. 380-389
-
-
Thakur, A.K.1
Jayaraman, M.2
Mishra, R.3
Thakur, M.4
Chellgren, V.M.5
Lbyeon, I.-J.6
Anjum, D.H.7
Kodali, R.8
Creamer, T.P.9
Conway, J.F.10
Mgronenborn, A.11
Wetzel, R.12
-
35
-
-
84906255971
-
Spontaneous selfassembly of pathogenic huntingtin exon 1 protein into amyloid structures
-
TREPTE, P., STREMPEL, N. & WANKER, E. E. (2014). Spontaneous selfassembly of pathogenic huntingtin exon 1 protein into amyloid structures. Essays in Biochemistry 56(167-180).
-
(2014)
Essays in Biochemistry
, vol.56
, Issue.167-180
-
-
Trepte, P.1
Strempel, N.2
Wanker, E.E.3
-
36
-
-
57049133956
-
Mutant huntingtin activates nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease
-
VAN ROON-MOM, W., PEPERS, B., T'HOEN, P., VERWIJMEREN, C., DEN DUNNEN, J., DORSMAN, J. & VAN OMMEN, G. (2008). Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease. BMC Molecular Biology 9(1), 84.
-
(2008)
BMC Molecular Biology
, vol.9
, Issue.1
, pp. 84
-
-
Van Roon-Mom, W.1
Pepers, B.2
T'Hoen, P.3
Verwijmeren, C.4
Den Dunnen, J.5
Dorsman, J.6
Van Ommen, G.7
-
37
-
-
84893675019
-
Structural biology: Order, disorder, and conformational flux
-
(ed. G. P. BATES, TABRIZI, S.J. & JONES, L.), New York: Oxford University Press
-
WETZEL, R. & MISHRA, R. (2014). Structural Biology: Order, disorder, and conformational flux. In Huntington's Disease (ed. G. P. BATES, TABRIZI, S.J. & JONES, L.), pp. 274-322. New York: Oxford University Press.
-
(2014)
Huntington's Disease
, pp. 274-322
-
-
Wetzel, R.1
Mishra, R.2
-
38
-
-
35748933204
-
STED microscopy with continuous wave beams
-
WILLIG, K. I., HARKE, B., MEDDA, R. & HELL, S.W. (2007). STED microscopy with continuous wave beams. Nature Methods 4(11), 915-918.
-
(2007)
Nature Methods
, vol.4
, Issue.11
, pp. 915-918
-
-
Willig, K.I.1
Harke, B.2
Medda, R.3
Hell, S.W.4
-
39
-
-
72349098331
-
Real-time computation of subdiffraction-resolution fluorescence images
-
WOLTER, S., SCHÜTTPELZ, M., TSCHEREPANOW, M., VAN DE LINDE, S., HEILEMANN, M. & SAUER, M. (2010). Real-time computation of subdiffraction-resolution fluorescence images. Journal of Microscopy 237(1), 12-22.
-
(2010)
Journal of Microscopy
, vol.237
, Issue.1
, pp. 12-22
-
-
Wolter, S.1
Schüttpelz, M.2
Tscherepanow, M.3
Van De-Linde, S.4
Heilemann, M.5
Sauer, M.6
|