Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity

Nature

Volumn 529, Issue 7587, 2016, Pages 532-536

  Luo, Chong T ^a   Liao, Will ^b   Dadi, Saida ^a   Toure, Ahmed ^a   Li, Ming O ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NEW YORK GENOME CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B INHIBITOR; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE;

CELLS AND CELL COMPONENTS; DIFFERENTIATION; ENZYME ACTIVITY; GENE EXPRESSION; IMMUNITY; PHENOTYPE; PHYSIOLOGICAL RESPONSE; RODENT; TOLERANCE; TUMOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ARTICLE; AUTOIMMUNITY; CANCER PATIENT; CANCER PROGNOSIS; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REPRESSION; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; LIVER INJURY; LYMPHOCYTE DIFFERENTIATION; LYMPHOID ORGAN; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUMOR GROWTH; TUMOR IMMUNITY; ANIMAL; BIOSYNTHESIS; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; FEMALE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MUTATION; NEOPLASM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR ASSOCIATED LEUKOCYTE;

MUS;

ANIMALS; AUTOIMMUNITY; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL MOVEMENT; DOWN-REGULATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; LYMPHOCYTE ACTIVATION; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MICE; MUTATION; NEOPLASMS; PHOSPHORYLATION; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRANSCRIPTION, GENETIC;

EID: 84956616968     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16486     Document Type: Article

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