-
1
-
-
43449084346
-
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
-
Akala OO, Park IK, Qian D, Pihalja M, Becker MW, Clarke MF (2008) Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors. Nature 453: 228- 232
-
(2008)
Nature
, vol.453
, pp. 228-232
-
-
Akala, O.O.1
Park, I.K.2
Qian, D.3
Pihalja, M.4
Becker, M.W.5
Clarke, M.F.6
-
2
-
-
73349143984
-
Niche recycling through division-independent egress of hematopoietic stem cells
-
Bhattacharya D, Czechowicz A, Ooi AG, Rossi DJ, Bryder D, Weissman IL (2009) Niche recycling through division-independent egress of hematopoietic stem cells. J Exp Med 206: 2837- 2850
-
(2009)
J Exp Med
, vol.206
, pp. 2837-2850
-
-
Bhattacharya, D.1
Czechowicz, A.2
Ooi, A.G.3
Rossi, D.J.4
Bryder, D.5
Weissman, I.L.6
-
3
-
-
0033607506
-
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
-
Bouillet P, Metcalf D, Huang DC, Tarlinton DM, Kay TW, Kontgen F, Adams JM, Strasser A (1999) Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735- 1738
-
(1999)
Science
, vol.286
, pp. 1735-1738
-
-
Bouillet, P.1
Metcalf, D.2
Huang, D.C.3
Tarlinton, D.M.4
Kay, T.W.5
Kontgen, F.6
Adams, J.M.7
Strasser, A.8
-
4
-
-
77449121923
-
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells
-
Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, et al (2010) Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. Cell Stem Cell 6: 251- 264
-
(2010)
Cell Stem Cell
, vol.6
, pp. 251-264
-
-
Butler, J.M.1
Nolan, D.J.2
Vertes, E.L.3
Varnum-Finney, B.4
Kobayashi, H.5
Hooper, A.T.6
Seandel, M.7
Shido, K.8
White, I.A.9
Kobayashi, M.10
-
5
-
-
77956583421
-
The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity
-
Campbell CJ, Lee JB, Levadoux-Martin M, Wynder T, Xenocostas A, Leber B, Bhatia M (2010a) The human stem cell hierarchy is defined by a functional dependence on Mcl-1 for self-renewal capacity. Blood 116: 1433- 1442
-
(2010)
Blood
, vol.116
, pp. 1433-1442
-
-
Campbell, C.J.1
Lee, J.B.2
Levadoux-Martin, M.3
Wynder, T.4
Xenocostas, A.5
Leber, B.6
Bhatia, M.7
-
6
-
-
78049371811
-
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance
-
Campbell KJ, Bath ML, Turner ML, Vandenberg CJ, Bouillet P, Metcalf D, Scott CL, Cory S (2010b) Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance. Blood 116: 3197- 3207
-
(2010)
Blood
, vol.116
, pp. 3197-3207
-
-
Campbell, K.J.1
Bath, M.L.2
Turner, M.L.3
Vandenberg, C.J.4
Bouillet, P.5
Metcalf, D.6
Scott, C.L.7
Cory, S.8
-
7
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L, Willis SN, Wei A, Smith BJ, Fletcher JI, Hinds MG, Colman PM, Day CL, Adams JM, Huang DC (2005) Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17: 393- 403
-
(2005)
Mol Cell
, vol.17
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
Colman, P.M.7
Day, C.L.8
Adams, J.M.9
Huang, D.C.10
-
8
-
-
0142117313
-
The Bcl-2 family: roles in cell survival and oncogenesis
-
Cory S, Huang DC, Adams JM (2003) The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22: 8590- 8607
-
(2003)
Oncogene
, vol.22
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.2
Adams, J.M.3
-
9
-
-
85047699482
-
Extensive early apoptosis in frozen-thawed CD34-positive stem cells decreases threshold doses for haematological recovery after autologous peripheral blood progenitor cell transplantation
-
de Boer F, Drager AM, Pinedo HM, Kessler FL, van der WE, Jonkhoff AR, van der LJ, Huijgens PC, Ossenkoppele GJ, Schuurhuis GJ (2002) Extensive early apoptosis in frozen-thawed CD34-positive stem cells decreases threshold doses for haematological recovery after autologous peripheral blood progenitor cell transplantation. Bone Marrow Transplant 29: 249- 255
-
(2002)
Bone Marrow Transplant
, vol.29
, pp. 249-255
-
-
de Boer, F.1
Drager, A.M.2
Pinedo, H.M.3
Kessler, F.L.4
van der, W.E.5
Jonkhoff, A.R.6
van der, L.J.7
Huijgens, P.C.8
Ossenkoppele, G.J.9
Schuurhuis, G.J.10
-
10
-
-
9044221363
-
Optimization of peripheral blood stem cell mobilization
-
Demirer T, Buckner CD, Bensinger WI (1996) Optimization of peripheral blood stem cell mobilization. Stem Cells 14: 106- 116
-
(1996)
Stem Cells
, vol.14
, pp. 106-116
-
-
Demirer, T.1
Buckner, C.D.2
Bensinger, W.I.3
-
11
-
-
0034677173
-
The role of apoptosis in the regulation of hematopoietic stem cells: overexpression of Bcl-2 increases both their number and repopulation potential
-
Domen J, Cheshier SH, Weissman IL (2000) The role of apoptosis in the regulation of hematopoietic stem cells: overexpression of Bcl-2 increases both their number and repopulation potential. J Exp Med 191: 253- 264
-
(2000)
J Exp Med
, vol.191
, pp. 253-264
-
-
Domen, J.1
Cheshier, S.H.2
Weissman, I.L.3
-
12
-
-
0032055166
-
Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation
-
Domen J, Gandy KL, Weissman IL (1998) Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood 91: 2272- 2282
-
(1998)
Blood
, vol.91
, pp. 2272-2282
-
-
Domen, J.1
Gandy, K.L.2
Weissman, I.L.3
-
13
-
-
0034684662
-
Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other
-
Domen J, Weissman IL (2000) Hematopoietic stem cells need two signals to prevent apoptosis; BCL-2 can provide one of these, Kitl/c-Kit signaling the other. J Exp Med 192: 1707- 1718
-
(2000)
J Exp Med
, vol.192
, pp. 1707-1718
-
-
Domen, J.1
Weissman, I.L.2
-
14
-
-
0038722038
-
Hematopoietic stem cells and other hematopoietic cells show broad resistance to chemotherapeutic agents in vivo when overexpressing bcl-2
-
Domen J, Weissman IL (2003) Hematopoietic stem cells and other hematopoietic cells show broad resistance to chemotherapeutic agents in vivo when overexpressing bcl-2. Exp Hematol 31: 631- 639
-
(2003)
Exp Hematol
, vol.31
, pp. 631-639
-
-
Domen, J.1
Weissman, I.L.2
-
16
-
-
84883843144
-
Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways
-
Eldering E, Spek CA, Aberson HL, Grummels A, Derks IA, de Vos AF, McElgunn CJ, Schouten JP (2003) Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways. Nucleic Acids Res 31: e153
-
(2003)
Nucleic Acids Res
, vol.31
-
-
Eldering, E.1
Spek, C.A.2
Aberson, H.L.3
Grummels, A.4
Derks, I.A.5
de Vos, A.F.6
McElgunn, C.J.7
Schouten, J.P.8
-
17
-
-
33845913794
-
Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction
-
Erlacher M, Labi V, Manzl C, Bock G, Tzankov A, Hacker G, Michalak E, Strasser A, Villunger A (2006) Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction. J Exp Med 203: 2939- 2951
-
(2006)
J Exp Med
, vol.203
, pp. 2939-2951
-
-
Erlacher, M.1
Labi, V.2
Manzl, C.3
Bock, G.4
Tzankov, A.5
Hacker, G.6
Michalak, E.7
Strasser, A.8
Villunger, A.9
-
18
-
-
0038155706
-
Elevation of Survivin levels by hematopoietic growth factors occurs in quiescent CD34+ hematopoietic stem and progenitor cells before cell cycle entry
-
Fukuda S, Pelus LM (2002) Elevation of Survivin levels by hematopoietic growth factors occurs in quiescent CD34+ hematopoietic stem and progenitor cells before cell cycle entry. Cell Cycle 1: 322- 326
-
(2002)
Cell Cycle
, vol.1
, pp. 322-326
-
-
Fukuda, S.1
Pelus, L.M.2
-
19
-
-
0037182861
-
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
-
Gerber HP, Malik AK, Solar GP, Sherman D, Liang XH, Meng G, Hong K, Marsters JC, Ferrara N (2002) VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature 417: 954- 958
-
(2002)
Nature
, vol.417
, pp. 954-958
-
-
Gerber, H.P.1
Malik, A.K.2
Solar, G.P.3
Sherman, D.4
Liang, X.H.5
Meng, G.6
Hong, K.7
Marsters, J.C.8
Ferrara, N.9
-
20
-
-
33645402975
-
Evaluation of the reactivity of apoptosis markers before and after cryopreservation in cord blood CD34(+) cells
-
Greco NJ, Seetharaman S, Kurtz J, Lee WR, Moroff G (2006) Evaluation of the reactivity of apoptosis markers before and after cryopreservation in cord blood CD34(+) cells. Stem Cells Dev 15: 124- 135
-
(2006)
Stem Cells Dev
, vol.15
, pp. 124-135
-
-
Greco, N.J.1
Seetharaman, S.2
Kurtz, J.3
Lee, W.R.4
Moroff, G.5
-
21
-
-
73549092480
-
Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo
-
Hubner A, Cavanagh-Kyros J, Rincon M, Flavell RA, Davis RJ (2010) Functional cooperation of the proapoptotic Bcl2 family proteins Bmf and Bim in vivo. Mol Cell Biol 30: 98- 105
-
(2010)
Mol Cell Biol
, vol.30
, pp. 98-105
-
-
Hubner, A.1
Cavanagh-Kyros, J.2
Rincon, M.3
Flavell, R.A.4
Davis, R.J.5
-
22
-
-
41149127750
-
Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development
-
Labi V, Erlacher M, Kiessling S, Manzl C, Frenzel A, O'Reilly L, Strasser A, Villunger A (2008) Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development. J Exp Med 205: 641- 655
-
(2008)
J Exp Med
, vol.205
, pp. 641-655
-
-
Labi, V.1
Erlacher, M.2
Kiessling, S.3
Manzl, C.4
Frenzel, A.5
O'Reilly, L.6
Strasser, A.7
Villunger, A.8
-
23
-
-
0030893390
-
Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell
-
Matsuzaki Y, Nakayama K, Nakayama K, Tomita T, Isoda M, Loh DY, Nakauchi H (1997) Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell. Blood 89: 853- 862
-
(1997)
Blood
, vol.89
, pp. 853-862
-
-
Matsuzaki, Y.1
Nakayama, K.2
Nakayama, K.3
Tomita, T.4
Isoda, M.5
Loh, D.Y.6
Nakauchi, H.7
-
24
-
-
0028922885
-
Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice
-
Motoyama N, Wang F, Roth KA, Sawa H, Nakayama K, Nakayama K, Negishi I, Senju S, Zhang Q, Fujii S, et al (1995) Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science 267: 1506- 1510
-
(1995)
Science
, vol.267
, pp. 1506-1510
-
-
Motoyama, N.1
Wang, F.2
Roth, K.A.3
Sawa, H.4
Nakayama, K.5
Nakayama, K.6
Negishi, I.7
Senju, S.8
Zhang, Q.9
Fujii, S.10
-
25
-
-
0033034215
-
Thrombopoietin, flt3, and kit ligands together suppress apoptosis of human mobilized CD34+ cells and recruit primitive CD34+ Thy-1+ cells into rapid division
-
Murray LJ, Young JC, Osborne LJ, Luens KM, Scollay R, Hill BL (1999) Thrombopoietin, flt3, and kit ligands together suppress apoptosis of human mobilized CD34+ cells and recruit primitive CD34+ Thy-1+ cells into rapid division. Exp Hematol 27: 1019- 1028
-
(1999)
Exp Hematol
, vol.27
, pp. 1019-1028
-
-
Murray, L.J.1
Young, J.C.2
Osborne, L.J.3
Luens, K.M.4
Scollay, R.5
Hill, B.L.6
-
26
-
-
0033593038
-
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival
-
Ogilvy S, Metcalf D, Print CG, Bath ML, Harris AW, Adams JM (1999) Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. Proc Natl Acad Sci USA 96: 14943- 14948
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14943-14948
-
-
Ogilvy, S.1
Metcalf, D.2
Print, C.G.3
Bath, M.L.4
Harris, A.W.5
Adams, J.M.6
-
27
-
-
78650722292
-
MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets
-
Ooi AG, Sahoo D, Adorno M, Wang Y, Weissman IL, Park CY (2010) MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc Natl Acad Sci USA 107: 21505- 21510
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21505-21510
-
-
Ooi, A.G.1
Sahoo, D.2
Adorno, M.3
Wang, Y.4
Weissman, I.L.5
Park, C.Y.6
-
28
-
-
13844319184
-
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells
-
Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ (2005) Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells. Science 307: 1101- 1104
-
(2005)
Science
, vol.307
, pp. 1101-1104
-
-
Opferman, J.T.1
Iwasaki, H.2
Ong, C.C.3
Suh, H.4
Mizuno, S.5
Akashi, K.6
Korsmeyer, S.J.7
-
29
-
-
2542418036
-
The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression
-
Orelio C, Harvey KN, Miles C, Oostendorp RA, van der HK, Dzierzak E (2004) The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression. Blood 103: 4084- 4092
-
(2004)
Blood
, vol.103
, pp. 4084-4092
-
-
Orelio, C.1
Harvey, K.N.2
Miles, C.3
Oostendorp, R.A.4
van der, H.K.5
Dzierzak, E.6
-
30
-
-
77956025424
-
In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days
-
Pillay J, den Braber I, Vrisekoop N, Kwast LM, de Boer RJ, Borghans JA, Tesselaar K, Koenderman L (2010) In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days. Blood 116: 625- 627
-
(2010)
Blood
, vol.116
, pp. 625-627
-
-
Pillay, J.1
den Braber, I.2
Vrisekoop, N.3
Kwast, L.M.4
de Boer, R.J.5
Borghans, J.A.6
Tesselaar, K.7
Koenderman, L.8
-
31
-
-
68149105937
-
Bim and Bmf in tissue homeostasis and malignant disease
-
Pinon JD, Labi V, Egle A, Villunger A (2008) Bim and Bmf in tissue homeostasis and malignant disease. Oncogene 27 (Suppl 1), S41- S52
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL 1
-
-
Pinon, J.D.1
Labi, V.2
Egle, A.3
Villunger, A.4
-
32
-
-
0035823238
-
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
-
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A (2001) Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 293: 1829- 1832
-
(2001)
Science
, vol.293
, pp. 1829-1832
-
-
Puthalakath, H.1
Villunger, A.2
O'Reilly, L.A.3
Beaumont, J.G.4
Coultas, L.5
Cheney, R.E.6
Huang, D.C.7
Strasser, A.8
-
33
-
-
36749001043
-
Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells
-
Qian H, Buza-Vidas N, Hyland CD, Jensen CT, Antonchuk J, Mansson R, Thoren LA, Ekblom M, Alexander WS, Jacobsen SE (2007) Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells. Cell Stem Cell 1: 671- 684
-
(2007)
Cell Stem Cell
, vol.1
, pp. 671-684
-
-
Qian, H.1
Buza-Vidas, N.2
Hyland, C.D.3
Jensen, C.T.4
Antonchuk, J.5
Mansson, R.6
Thoren, L.A.7
Ekblom, M.8
Alexander, W.S.9
Jacobsen, S.E.10
-
34
-
-
0042424706
-
Bad-deficient mice develop diffuse large B cell lymphoma
-
Ranger AM, Zha J, Harada H, Datta SR, Danial NN, Gilmore AP, Kutok JL, Le Beau MM, Greenberg ME, Korsmeyer SJ (2003) Bad-deficient mice develop diffuse large B cell lymphoma. Proc Natl Acad Sci USA 100: 9324- 9329
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9324-9329
-
-
Ranger, A.M.1
Zha, J.2
Harada, H.3
Datta, S.R.4
Danial, N.N.5
Gilmore, A.P.6
Kutok, J.L.7
Le Beau, M.M.8
Greenberg, M.E.9
Korsmeyer, S.J.10
-
35
-
-
77953044213
-
New approaches for improving engraftment after cord blood transplantation
-
Rocha V, Broxmeyer HE (2010) New approaches for improving engraftment after cord blood transplantation. Biol Blood Marrow Transplant 16: S126- S132
-
(2010)
Biol Blood Marrow Transplant
, vol.16
-
-
Rocha, V.1
Broxmeyer, H.E.2
-
36
-
-
77955512131
-
Of mice and men: human RNA polymerase III promoter U6 is more efficient than its murine homologue for shRNA expression from a lentiviral vector in both human and murine progenitor cells
-
Roelz R, Pilz IH, Mutschler M, Pahl HL (2010) Of mice and men: human RNA polymerase III promoter U6 is more efficient than its murine homologue for shRNA expression from a lentiviral vector in both human and murine progenitor cells. Exp Hematol 38: 792- 797
-
(2010)
Exp Hematol
, vol.38
, pp. 792-797
-
-
Roelz, R.1
Pilz, I.H.2
Mutschler, M.3
Pahl, H.L.4
-
37
-
-
0035072475
-
Large populations of non-clonogenic early apoptotic CD34-positive cells are present in frozen-thawed peripheral blood stem cell transplants
-
Schuurhuis GJ, Muijen MM, Oberink JW, de Boer F, Ossenkoppele GJ, Broxterman HJ (2001) Large populations of non-clonogenic early apoptotic CD34-positive cells are present in frozen-thawed peripheral blood stem cell transplants. Bone Marrow Transplant 27: 487- 498
-
(2001)
Bone Marrow Transplant
, vol.27
, pp. 487-498
-
-
Schuurhuis, G.J.1
Muijen, M.M.2
Oberink, J.W.3
de Boer, F.4
Ossenkoppele, G.J.5
Broxterman, H.J.6
-
38
-
-
14944348965
-
The role of BH3-only proteins in the immune system
-
Strasser A (2005) The role of BH3-only proteins in the immune system. Nat Rev Immunol 5: 189- 200
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 189-200
-
-
Strasser, A.1
-
39
-
-
0025251664
-
Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2
-
Strasser A, Harris AW, Bath ML, Cory S (1990) Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2. Nature 348: 331- 333
-
(1990)
Nature
, vol.348
, pp. 331-333
-
-
Strasser, A.1
Harris, A.W.2
Bath, M.L.3
Cory, S.4
-
40
-
-
1842588698
-
Development of a human adaptive immune system in cord blood cell-transplanted mice
-
Traggiai E, Chicha L, Mazzucchelli L, Bronz L, Piffaretti JC, Lanzavecchia A, Manz MG (2004) Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 304: 104- 107
-
(2004)
Science
, vol.304
, pp. 104-107
-
-
Traggiai, E.1
Chicha, L.2
Mazzucchelli, L.3
Bronz, L.4
Piffaretti, J.C.5
Lanzavecchia, A.6
Manz, M.G.7
-
41
-
-
0033694305
-
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
-
Varnum-Finney B, Xu L, Brashem-Stein C, Nourigat C, Flowers D, Bakkour S, Pear WS, Bernstein ID (2000) Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nat Med 6: 1278- 1281
-
(2000)
Nat Med
, vol.6
, pp. 1278-1281
-
-
Varnum-Finney, B.1
Xu, L.2
Brashem-Stein, C.3
Nourigat, C.4
Flowers, D.5
Bakkour, S.6
Pear, W.S.7
Bernstein, I.D.8
-
42
-
-
0027427492
-
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
-
Veis DJ, Sorenson CM, Shutter JR, Korsmeyer SJ (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell 75: 229- 240
-
(1993)
Cell
, vol.75
, pp. 229-240
-
-
Veis, D.J.1
Sorenson, C.M.2
Shutter, J.R.3
Korsmeyer, S.J.4
-
43
-
-
0242410719
-
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa
-
Villunger A, Michalak EM, Coultas L, Mullauer F, Bock G, Ausserlechner MJ, Adams JM, Strasser A (2003) p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa. Science 302: 1036- 1038
-
(2003)
Science
, vol.302
, pp. 1036-1038
-
-
Villunger, A.1
Michalak, E.M.2
Coultas, L.3
Mullauer, F.4
Bock, G.5
Ausserlechner, M.J.6
Adams, J.M.7
Strasser, A.8
-
44
-
-
0031990830
-
Rescue from apoptosis in early (CD34-selected) versus late (non-CD34-selected) human hematopoietic cells by very late antigen 4- and vascular cell adhesion molecule (VCAM) 1-dependent adhesion to bone marrow stromal cells
-
Wang MW, Consoli U, Lane CM, Durett A, Lauppe MJ, Champlin R, Andreeff M, Deisseroth AB (1998) Rescue from apoptosis in early (CD34-selected) versus late (non-CD34-selected) human hematopoietic cells by very late antigen 4- and vascular cell adhesion molecule (VCAM) 1-dependent adhesion to bone marrow stromal cells. Cell Growth Differ 9: 105- 112
-
(1998)
Cell Growth Differ
, vol.9
, pp. 105-112
-
-
Wang, M.W.1
Consoli, U.2
Lane, C.M.3
Durett, A.4
Lauppe, M.J.5
Champlin, R.6
Andreeff, M.7
Deisseroth, A.B.8
-
45
-
-
71849114718
-
Balancing dormant and self-renewing hematopoietic stem cells
-
Wilson A, Laurenti E, Trumpp A (2009) Balancing dormant and self-renewing hematopoietic stem cells. Curr Opin Genet Dev 19: 461- 468
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 461-468
-
-
Wilson, A.1
Laurenti, E.2
Trumpp, A.3
-
46
-
-
78649630259
-
Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity
-
Wilson WH, O'Connor OA, Czuczman MS, LaCasce AS, Gerecitano JF, Leonard JP, Tulpule A, Dunleavy K, Xiong H, Chiu YL, et al (2010) Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity. Lancet Oncol 11: 1149- 1159
-
(2010)
Lancet Oncol
, vol.11
, pp. 1149-1159
-
-
Wilson, W.H.1
O'Connor, O.A.2
Czuczman, M.S.3
LaCasce, A.S.4
Gerecitano, J.F.5
Leonard, J.P.6
Tulpule, A.7
Dunleavy, K.8
Xiong, H.9
Chiu, Y.L.10
-
47
-
-
33745841375
-
FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal
-
You H, Pellegrini M, Tsuchihara K, Yamamoto K, Hacker G, Erlacher M, Villunger A, Mak TW (2006) FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal. J Exp Med 203: 1657- 1663
-
(2006)
J Exp Med
, vol.203
, pp. 1657-1663
-
-
You, H.1
Pellegrini, M.2
Tsuchihara, K.3
Yamamoto, K.4
Hacker, G.5
Erlacher, M.6
Villunger, A.7
Mak, T.W.8
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