CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer

International Journal of Cancer

Volumn 138, Issue 5, 2016, Pages 1207-1219

  Izumi, Daisuke ^a   Ishimoto, Takatsugu ^a,b   Miyake, Keisuke ^a   Sugihara, Hidetaka ^a   Eto, Kojiro ^a   Sawayama, Hiroshi ^a   Yasuda, Tadahito ^a   Kiyozumi, Yuki ^a   Kaida, Takayoshi ^a   Kurashige, Junji ^a   Imamura, Yu ^a   Hiyoshi, Yukiharu ^a   Iwatsuki, Masaaki ^c   Iwagami, Shiro ^a   Baba, Yoshifumi ^a   Sakamoto, Yasuo ^a   Miyamoto, Yuji ^a   Yoshida, Naoya ^a   Watanabe, Masayuki ^d   Takamori, Hiroshi ^c   Araki, Norie ^a   Tan, Patrick ^b   Baba, Hideo ^a   more..

^a KUMAMOTO UNIVERSITY   (Japan)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

^c SAISEIKAI KUMAMOTO HOSPITAL   (Japan)

^d CANCER INSTITUTE HOSPITAL   (Japan)

Author keywords

cancer associated fibroblasts; CXCL12; CXCR4; gastric cancer; integrin 1

Indexed keywords

BETA1 INTEGRIN; CD31 ANTIGEN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; EPITHELIAL CELL ADHESION MOLECULE; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; PF 573228; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLERIXAFOR; SEPRASE; STROMAL CELL DERIVED FACTOR 1; THY 1 ANTIGEN; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN;

AGED; ARTICLE; CANCER ASSOCIATED FIBROBLAST; CANCER PROGNOSIS; CELL SURFACE; COCULTURE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; FEMALE; FIBROBLAST; FIBROBLAST CULTURE; GASTRECTOMY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STOMACH CANCER; TUMOR INVASION; TUMOR LOCALIZATION; TUMOR VOLUME; ANTAGONISTS AND INHIBITORS; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; STOMACH TUMOR; TUMOR CELL LINE;

AGED; ANTIGENS, CD29; CELL LINE, TUMOR; CHEMOKINE CXCL12; FEMALE; FIBROBLASTS; FOCAL ADHESION PROTEIN-TYROSINE KINASES; HUMANS; MALE; NEOPLASM INVASIVENESS; PROGNOSIS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 84955713026     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29864     Document Type: Article

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