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Volumn 36, Issue 2, 2016, Pages 380-388

MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular Injury

Author keywords

adherens junctions; angiopoietin 2; endothelial growth response 2; endothelium; lung injury; miR 150; sepsis

Indexed keywords

ANGIOPOIETIN 2; BETA CATENIN; EARLY GROWTH RESPONSE FACTOR 2; LIPOPOLYSACCHARIDE; MICRORNA; MICRORNA 150; MYOSIN LIGHT CHAIN KINASE; UNCLASSIFIED DRUG; VASCULAR ENDOTHELIAL CADHERIN; ANGPT2 PROTEIN, HUMAN; EGR2 PROTEIN, HUMAN; MIRN150 MICRORNA, HUMAN; MIRN150 MICRORNA, MOUSE;

EID: 84955708236     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.306997     Document Type: Article
Times cited : (47)

References (52)
  • 1
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D, Malik AB, Signaling mechanisms regulating endothelial permeability. Physiol Rev 2006 86 279 367. doi: 10.1152/physrev.00012.2005.
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 2
    • 38449083544 scopus 로고    scopus 로고
    • Dual regulation of endothelial junctional permeability
    • Komarova YA, Mehta D, Malik AB, Dual regulation of endothelial junctional permeability. Sci STKE 2007 2007 re8. doi: 10.1126/stke.4122007re8.
    • (2007) Sci STKE , vol.2007 , pp. re8
    • Komarova, Y.A.1    Mehta, D.2    Malik, A.B.3
  • 4
    • 41149164199 scopus 로고    scopus 로고
    • Regulation of endothelial junctional permeability
    • Vandenbroucke E, Mehta D, Minshall R, Malik AB, Regulation of endothelial junctional permeability. Ann N Y Acad Sci 2008 1123 134 145. doi: 10.1196/annals.1420.016.
    • (2008) Ann N y Acad Sci , vol.1123 , pp. 134-145
    • Vandenbroucke, E.1    Mehta, D.2    Minshall, R.3    Malik, A.B.4
  • 7
    • 73349090278 scopus 로고    scopus 로고
    • The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin
    • Knezevic N, Tauseef M, Thennes T, Mehta D, The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin. J Exp Med 2009 206 2761 2777. doi: 10.1084/jem.20090652.
    • (2009) J Exp Med , vol.206 , pp. 2761-2777
    • Knezevic, N.1    Tauseef, M.2    Thennes, T.3    Mehta, D.4
  • 8
    • 79751520659 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome: Pathogenesis and treatment
    • Matthay MA, Zemans RL, The acute respiratory distress syndrome: pathogenesis and treatment. Annu Rev Pathol 2011 6 147 163. doi: 10.1146/annurev-pathol-011110-130158.
    • (2011) Annu Rev Pathol , vol.6 , pp. 147-163
    • Matthay, M.A.1    Zemans, R.L.2
  • 10
    • 0242405592 scopus 로고    scopus 로고
    • Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis
    • Thurston G, Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis. Cell Tissue Res 2003 314 61 68. doi: 10.1007/s00441-003-0749-6.
    • (2003) Cell Tissue Res , vol.314 , pp. 61-68
    • Thurston, G.1
  • 14
    • 84897402975 scopus 로고    scopus 로고
    • Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression
    • Mammoto T, Jiang E, Jiang A, Lu Y, Juan AM, Chen J, Mammoto A, Twist1 controls lung vascular permeability and endotoxin-induced pulmonary edema by altering Tie2 expression. PLoS One 2013 8 e73407. doi: 10.1371/journal.pone.0073407.
    • (2013) PLoS One , vol.8 , pp. e73407
    • Mammoto, T.1    Jiang, E.2    Jiang, A.3    Lu, Y.4    Juan, A.M.5    Chen, J.6    Mammoto, A.7
  • 16
    • 84873510243 scopus 로고    scopus 로고
    • The role of angiogenic factors and their soluble receptors in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) associated with critical illness
    • Wada T, Jesmin S, Gando S, Yanagida Y, Mizugaki A, Sultana SN, Zaedi S, Yokota H, The role of angiogenic factors and their soluble receptors in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) associated with critical illness. J Inflamm (Lond) 2013 10 6. doi: 10.1186/1476-9255-10-6.
    • (2013) J Inflamm (Lond) , vol.10 , pp. 6
    • Wada, T.1    Jesmin, S.2    Gando, S.3    Yanagida, Y.4    Mizugaki, A.5    Sultana, S.N.6    Zaedi, S.7    Yokota, H.8
  • 17
    • 84871277703 scopus 로고    scopus 로고
    • Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation
    • Diamond JM, Porteous MK, Cantu E, Lung Transplant Outcomes Group Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation. PLoS One 2012 7 e51932. doi: 10.1371/journal.pone.0051932.
    • (2012) PLoS One , vol.7 , pp. e51932
    • Diamond, J.M.1    Porteous, M.K.2    Cantu, E.3
  • 18
    • 79956207348 scopus 로고    scopus 로고
    • ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio
    • Meyer NJ, Li M, Feng R, ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med 2011 183 1344 1353. doi: 10.1164/rccm.201005-0701OC.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 1344-1353
    • Meyer, N.J.1    Li, M.2    Feng, R.3
  • 22
    • 0035412821 scopus 로고    scopus 로고
    • Human angiopoietin gene expression is a marker for severity of pulmonary hypertension in patients undergoing pulmonary thromboendarterectomy
    • Thistlethwaite PA, Lee SH, Du LL, Wolf PL, Sullivan C, Pradhan S, Deutsch R, Jamieson SW, Human angiopoietin gene expression is a marker for severity of pulmonary hypertension in patients undergoing pulmonary thromboendarterectomy. J Thorac Cardiovasc Surg 2001 122 65 73. doi: 10.1067/mtc.2001.113753.
    • (2001) J Thorac Cardiovasc Surg , vol.122 , pp. 65-73
    • Thistlethwaite, P.A.1    Lee, S.H.2    Du, L.L.3    Wolf, P.L.4    Sullivan, C.5    Pradhan, S.6    Deutsch, R.7    Jamieson, S.W.8
  • 23
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP, MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004 116 281 297
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 24
    • 79955608010 scopus 로고    scopus 로고
    • MiRNAs and regulation of cell signaling
    • Ichimura A, Ruike Y, Terasawa K, Tsujimoto G, miRNAs and regulation of cell signaling. FEBS J 2011 278 1610 1618. doi: 10.1111/j.1742-4658.2011.08087.x.
    • (2011) FEBS J , vol.278 , pp. 1610-1618
    • Ichimura, A.1    Ruike, Y.2    Terasawa, K.3    Tsujimoto, G.4
  • 27
    • 84885164941 scopus 로고    scopus 로고
    • MicroRNA-200C and-150 play an important role in endothelial cell differentiation and vasculogenesis by targeting transcription repressor ZEB1
    • Luo Z, Wen G, Wang G, Pu X, Ye S, Xu Q, Wang W, Xiao Q, MicroRNA-200C and-150 play an important role in endothelial cell differentiation and vasculogenesis by targeting transcription repressor ZEB1. Stem Cells 2013 31 1749 1762. doi: 10.1002/stem.1448.
    • (2013) Stem Cells , vol.31 , pp. 1749-1762
    • Luo, Z.1    Wen, G.2    Wang, G.3    Pu, X.4    Ye, S.5    Xu, Q.6    Wang, W.7    Xiao, Q.8
  • 28
    • 58149174403 scopus 로고    scopus 로고
    • Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells
    • Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D, Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circ Res 2008 103 1164 1172. doi: 10.1161/01.RES.0000338501.84810.51.
    • (2008) Circ Res , vol.103 , pp. 1164-1172
    • Tauseef, M.1    Kini, V.2    Knezevic, N.3    Brannan, M.4    Ramchandaran, R.5    Fyrst, H.6    Saba, J.7    Vogel, S.M.8    Malik, A.B.9    Mehta, D.10
  • 30
    • 44449145867 scopus 로고    scopus 로고
    • Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome
    • Gallagher DC, Parikh SM, Balonov K, Miller A, Gautam S, Talmor D, Sukhatme VP, Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome. Shock 2008 29 656 661. doi: 10.1097/shk.0b013e31815dd92f.
    • (2008) Shock , vol.29 , pp. 656-661
    • Gallagher, D.C.1    Parikh, S.M.2    Balonov, K.3    Miller, A.4    Gautam, S.5    Talmor, D.6    Sukhatme, V.P.7
  • 32
    • 84883303630 scopus 로고    scopus 로고
    • The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases
    • Minami T, Jiang S, Schadler K, Suehiro J, Osawa T, Oike Y, Miura M, Naito M, Kodama T, Ryeom S, The calcineurin-NFAT-angiopoietin-2 signaling axis in lung endothelium is critical for the establishment of lung metastases. Cell Rep 2013 4 709 723. doi: 10.1016/j.celrep.2013.07.021.
    • (2013) Cell Rep , vol.4 , pp. 709-723
    • Minami, T.1    Jiang, S.2    Schadler, K.3    Suehiro, J.4    Osawa, T.5    Oike, Y.6    Miura, M.7    Naito, M.8    Kodama, T.9    Ryeom, S.10
  • 33
    • 84863707683 scopus 로고    scopus 로고
    • Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells
    • Deleuze V, El-Hajj R, Chalhoub E, Dohet C, Pinet V, Couttet P, Mathieu D, Angiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cells. PLoS One 2012 7 e40484. doi: 10.1371/journal.pone.0040484.
    • (2012) PLoS One , vol.7 , pp. e40484
    • Deleuze, V.1    El-Hajj, R.2    Chalhoub, E.3    Dohet, C.4    Pinet, V.5    Couttet, P.6    Mathieu, D.7
  • 35
    • 79959805164 scopus 로고    scopus 로고
    • MiRWalk-database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes
    • Dweep H, Sticht C, Pandey P, Gretz N, miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform 2011 44 839 847. doi: 10.1016/j.jbi.2011.05.002.
    • (2011) J Biomed Inform , vol.44 , pp. 839-847
    • Dweep, H.1    Sticht, C.2    Pandey, P.3    Gretz, N.4
  • 36
    • 84928396514 scopus 로고    scopus 로고
    • Therapeutic opportunities for targeting microRNAs in cancer
    • Taylor MA, Schiemann WP, Therapeutic opportunities for targeting microRNAs in cancer. Mol Cell Ther 2014 2 1 13. doi: 10.1186/2052-8426-2-30.
    • (2014) Mol Cell Ther , vol.2 , pp. 1-13
    • Taylor, M.A.1    Schiemann, W.P.2
  • 37
    • 33644855668 scopus 로고    scopus 로고
    • Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: Role in regulation of endothelial permeability
    • Holinstat M, Knezevic N, Broman M, Samarel AM, Malik AB, Mehta D, Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability. J Biol Chem 2006 281 2296 2305. doi: 10.1074/jbc.M511248200.
    • (2006) J Biol Chem , vol.281 , pp. 2296-2305
    • Holinstat, M.1    Knezevic, N.2    Broman, M.3    Samarel, A.M.4    Malik, A.B.5    Mehta, D.6
  • 38
    • 84891522360 scopus 로고    scopus 로고
    • Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27
    • Young JA, Ting KK, Li J, Regulation of vascular leak and recovery from ischemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood 2013 122 2911 2919. doi: 10.1182/blood-2012-12-473017.
    • (2013) Blood , vol.122 , pp. 2911-2919
    • Young, J.A.1    Ting, K.K.2    Li, J.3
  • 39
    • 60549094934 scopus 로고    scopus 로고
    • In vivo profile of the human leukocyte microRNA response to endotoxemia
    • Schmidt WM, Spiel AO, Jilma B, Wolzt M, Müller M, In vivo profile of the human leukocyte microRNA response to endotoxemia. Biochem Biophys Res Commun 2009 380 437 441. doi: 10.1016/j.bbrc.2008.12.190.
    • (2009) Biochem Biophys Res Commun , vol.380 , pp. 437-441
    • Schmidt, W.M.1    Spiel, A.O.2    Jilma, B.3    Wolzt, M.4    Müller, M.5
  • 43
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekström K, Bossios A, Sjöstrand M, Lee JJ, Lötvall JO, Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol 2007 9 654 659. doi: 10.1038/ncb1596.
    • (2007) Nat Cell Biol , vol.9 , pp. 654-659
    • Valadi, H.1    Ekström, K.2    Bossios, A.3    Sjöstrand, M.4    Lee, J.J.5    Lötvall, J.O.6
  • 44
    • 84944887229 scopus 로고    scopus 로고
    • MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension
    • Deng L, Blanco FJ, Stevens H, MicroRNA-143 activation regulates smooth muscle and endothelial cell crosstalk in pulmonary arterial hypertension. Circ Res 2015 117 870 883. doi: 10.1161/CIRCRESAHA.115.306806.
    • (2015) Circ Res , vol.117 , pp. 870-883
    • Deng, L.1    Blanco, F.J.2    Stevens, H.3
  • 46
    • 84923766524 scopus 로고    scopus 로고
    • Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells
    • Menden H, Welak S, Cossette S, Ramchandran R, Sampath V, Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells. J Biol Chem 2015 290 5449 5461. doi: 10.1074/jbc.M114.600692.
    • (2015) J Biol Chem , vol.290 , pp. 5449-5461
    • Menden, H.1    Welak, S.2    Cossette, S.3    Ramchandran, R.4    Sampath, V.5
  • 48
    • 79958167861 scopus 로고    scopus 로고
    • The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates profibrotic responses
    • Fang F, Ooka K, Bhattacharyya S, Bhattachyya S, Wei J, Wu M, Du P, Lin S, Del Galdo F, Feghali-Bostwick CA, Varga J, The early growth response gene Egr2 (Alias Krox20) is a novel transcriptional target of transforming growth factor-β that is up-regulated in systemic sclerosis and mediates profibrotic responses. Am J Pathol 2011 178 2077 2090. doi: 10.1016/j.ajpath.2011.01.035.
    • (2011) Am J Pathol , vol.178 , pp. 2077-2090
    • Fang, F.1    Ooka, K.2    Bhattacharyya, S.3    Bhattachyya, S.4    Wei, J.5    Wu, M.6    Du, P.7    Lin, S.8    Del Galdo, F.9    Feghali-Bostwick, C.A.10    Varga, J.11
  • 49
    • 84880053827 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression
    • Chandra A, Lan S, Zhu J, Siclari VA, Qin L, Epidermal growth factor receptor (EGFR) signaling promotes proliferation and survival in osteoprogenitors by increasing early growth response 2 (EGR2) expression. J Biol Chem 2013 288 20488 20498. doi: 10.1074/jbc.M112.447250.
    • (2013) J Biol Chem , vol.288 , pp. 20488-20498
    • Chandra, A.1    Lan, S.2    Zhu, J.3    Siclari, V.A.4    Qin, L.5
  • 51
    • 37549048594 scopus 로고    scopus 로고
    • An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer
    • Dillon RL, Brown ST, Ling C, Shioda T, Muller WJ, An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Mol Cell Biol 2007 27 8648 8657. doi: 10.1128/MCB.00866-07.
    • (2007) Mol Cell Biol , vol.27 , pp. 8648-8657
    • Dillon, R.L.1    Brown, S.T.2    Ling, C.3    Shioda, T.4    Muller, W.J.5


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