-
1
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE (2003) The pathophysiology and treatment of sepsis. N Engl J Med 348: 138-150.
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
2
-
-
0026710191
-
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
-
American College of Chest Physicians/Society of Critical Care Medicine. Chest
-
Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, et al. (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101: 1644-1655.
-
(1992)
The ACCP/SCCM Consensus Conference Committee
, vol.101
, pp. 1644-1655
-
-
Bone, R.C.1
Balk, R.A.2
Cerra, F.B.3
Dellinger, R.P.4
Fein, A.M.5
-
3
-
-
34247338128
-
Rapid increase in hospitalization and DEADality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003
-
Dombrovskiy VY, Martin AA, Sunderram J, Paz HL (2003) Rapid increase in hospitalization and DEADality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 35: 1244-50.
-
(2003)
Crit Care Med
, vol.35
, pp. 1244-1250
-
-
Dombrovskiy, V.Y.1
Martin, A.A.2
Sunderram, J.3
Paz, H.L.4
-
4
-
-
1542285975
-
Relaparotomy for suspected intraperitoneal sepsis after abdominal surgery
-
Hutchins RR, Gunning PM, Lucas DN, Allen-Mersh TG, Soni NC (2004) Relaparotomy for suspected intraperitoneal sepsis after abdominal surgery. World J Surg 28: 137-141.
-
(2004)
World J Surg
, vol.28
, pp. 137-141
-
-
Hutchins, R.R.1
Gunning, P.M.2
Lucas, D.N.3
Allen-Mersh, T.G.4
Soni, N.C.5
-
5
-
-
34247196096
-
Postoperative Bacterial/Fungal Infections: A Challenging Problem in Critically Ill Patients after Abdominal Surgery
-
Lichtenstern C, Schmidt J, Knaebel HP, Martin E, Büchler MW, et al. (2007) Postoperative Bacterial/Fungal Infections: A Challenging Problem in Critically Ill Patients after Abdominal Surgery. Dig Surg 24: 1-11.
-
(2007)
Dig Surg
, vol.24
, pp. 1-11
-
-
Lichtenstern, C.1
Schmidt, J.2
Knaebel, H.P.3
Martin, E.4
Büchler, M.W.5
-
6
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6: 857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
7
-
-
63049085576
-
MicroRNAs - The micro steering wheel of tumor metastases
-
Nicoloso MS, Spizzo R, Shimizu M, Rossi S, Calin GA (2009) MicroRNAs - The micro steering wheel of tumor metastases. Nat Rev Cancer 9: 293-302.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 293-302
-
-
Nicoloso, M.S.1
Spizzo, R.2
Shimizu, M.3
Rossi, S.4
Calin, G.A.5
-
8
-
-
34249736846
-
microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder
-
Perkins DO, Jeffries CD, Jarskog LF, Thomson JM, Woods K, et al. (2007) microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol 8: R27.
-
(2007)
Genome Biol
, vol.8
-
-
Perkins, D.O.1
Jeffries, C.D.2
Jarskog, L.F.3
Thomson, J.M.4
Woods, K.5
-
9
-
-
57349186092
-
MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy
-
Wang Q, Wang Y, Minto AW, Wang J, Shi Q, et al. (2008) MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J 22: 4126-4135.
-
(2008)
FASEB J
, vol.22
, pp. 4126-4135
-
-
Wang, Q.1
Wang, Y.2
Minto, A.W.3
Wang, J.4
Shi, Q.5
-
10
-
-
55249119513
-
MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha
-
Wu F, Zikusoka M, Trindade A, Dassopoulos T, Harris ML, et al. (2008) MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha. Gastroenterology 135: 1624-1635.
-
(2008)
Gastroenterology
, vol.135
, pp. 1624-1635
-
-
Wu, F.1
Zikusoka, M.2
Trindade, A.3
Dassopoulos, T.4
Harris, M.L.5
-
11
-
-
65249122551
-
MicroRNA expression profiles predictive of human renal allograft status
-
Anglicheau D, Sharma VK, Ding R, Hummel A, Snopkowski C, et al. (2009) MicroRNA expression profiles predictive of human renal allograft status. Proc Natl Acad Sci U S A 106: 5330-5335.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5330-5335
-
-
Anglicheau, D.1
Sharma, V.K.2
Ding, R.3
Hummel, A.4
Snopkowski, C.5
-
12
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V (2004) The functions of animal microRNAs. Nature 431: 350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
13
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
-
Tili E, Michaille JJ, Cimino A, Costinean S, Dumitru CD, et al. (2007) Modulation of miR-155 and miR-125b levels following lipopolysaccharide/ TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 179: 5082-5089.
-
(2007)
J Immunol
, vol.179
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.J.2
Cimino, A.3
Costinean, S.4
Dumitru, C.D.5
-
14
-
-
67649120071
-
MicroRNA identification in plasma and serum: A novel tool to diagnose and monitor diseases
-
Cortez A, Calin GA (2009) MicroRNA identification in plasma and serum: a novel tool to diagnose and monitor diseases. Expert Opinion in Biological Therapy 9: 703-711.
-
(2009)
Expert Opinion in Biological Therapy
, vol.9
, pp. 703-711
-
-
Cortez, A.1
Calin, G.A.2
-
15
-
-
0033944073
-
Elevation of IL-18 in human sepsis
-
Grobmyer SR, Lin E, Lowry SF, Rivadeneira DE, Potter S, et al. (2000) Elevation of IL-18 in human sepsis. J Clin Immunol 20: 212-215.
-
(2000)
J Clin Immunol
, vol.20
, pp. 212-215
-
-
Grobmyer, S.R.1
Lin, E.2
Lowry, S.F.3
Rivadeneira, D.E.4
Potter, S.5
-
16
-
-
0035653851
-
Interleukin-18 plasma levels are increased in patients with sepsis compared to severely injured patients
-
Oberholzer A, Steckholzer U, Kurimoto M, Trentz O, Ertel W (2001) Interleukin-18 plasma levels are increased in patients with sepsis compared to severely injured patients. Shock 16: 411-414.
-
(2001)
Shock
, vol.16
, pp. 411-414
-
-
Oberholzer, A.1
Steckholzer, U.2
Kurimoto, M.3
Trentz, O.4
Ertel, W.5
-
17
-
-
34547912524
-
-
ZakiMel-S, Elgendy MY, El-Mashad NB, Farahat ME (2007) IL-18 level correlates with development of sepsis in surgical patients. Immunol Invest 36: 403-411.
-
ZakiMel-S, Elgendy MY, El-Mashad NB, Farahat ME (2007) IL-18 level correlates with development of sepsis in surgical patients. Immunol Invest 36: 403-411.
-
-
-
-
18
-
-
40749112792
-
Wnt5A/ CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10
-
Pereira C, Schaer DJ, Bachli EB, Kurrer MO, Schoedon G (2008) Wnt5A/ CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10. Arterioscler Thromb Vasc Biol 28: 504-510.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 504-510
-
-
Pereira, C.1
Schaer, D.J.2
Bachli, E.B.3
Kurrer, M.O.4
Schoedon, G.5
-
19
-
-
40749157135
-
Wnt pathway: A new role in regulation of inflammation
-
George SJ (2008) Wnt pathway: a new role in regulation of inflammation. Arterioscler Thromb Vasc Biol 28: 400-402.
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 400-402
-
-
George, S.J.1
-
20
-
-
70350719428
-
-
Metab Syndr Relat Disord
-
Das S, Misra B, Roul L, Minz NT, Pattnaik M, Baig MA (2008) Insulin Resistance and beta Cell Function As Prognostic Indicator in Multi-Organ Dysfunction Syndrome. Metab Syndr Relat Disord.
-
(2008)
Insulin Resistance and beta Cell Function As Prognostic Indicator in Multi-Organ Dysfunction Syndrome
-
-
Das, S.1
Misra, B.2
Roul, L.3
Minz, N.T.4
Pattnaik, M.5
Baig, M.A.6
-
21
-
-
67650188910
-
-
Injury
-
Barkhausen T, Probst C, Hildebrand F, Pape HC, Krettek C, van Griensven M (2009) Insulin therapy induces changes in the inflammatory response in a murine 2-hit model. Injury.
-
(2009)
Insulin therapy induces changes in the inflammatory response in a murine 2-hit model
-
-
Barkhausen, T.1
Probst, C.2
Hildebrand, F.3
Pape, H.C.4
Krettek, C.5
van Griensven, M.6
-
22
-
-
48949119355
-
Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium
-
Koff JL, Shao MX, Ueki IF, Nadel JA (2008) Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium. Am J Physiol Lung Cell Mol Physiol 294: L1068-1075.
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.294
-
-
Koff, J.L.1
Shao, M.X.2
Ueki, I.F.3
Nadel, J.A.4
-
23
-
-
54949109311
-
-
Weichhart T, G. Costantino G, Poglitsch M, Rosner M, Zeyda M, et al. (2008) The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29: 565-577.
-
Weichhart T, G. Costantino G, Poglitsch M, Rosner M, Zeyda M, et al. (2008) The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29: 565-577.
-
-
-
-
24
-
-
58149326737
-
Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production
-
Németh K, Leelahavanichkul A, Yuen PS, Mayer B, Parmelee A, et al. (2009) Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 15: 42-49.
-
(2009)
Nat Med
, vol.15
, pp. 42-49
-
-
Németh, K.1
Leelahavanichkul, A.2
Yuen, P.S.3
Mayer, B.4
Parmelee, A.5
-
25
-
-
43049085950
-
Up-regulation of interleukin-10 mRNA expression in peripheral leukocytes predicts poor outcome and diminished human leukocyte antigen-DR expression on monocytes in septic patients
-
Abe R, Hirasawa H, Oda S, Sadahiro T, Nakamura M, et al. (2008) Up-regulation of interleukin-10 mRNA expression in peripheral leukocytes predicts poor outcome and diminished human leukocyte antigen-DR expression on monocytes in septic patients. J Surg Res 147: 1-8.
-
(2008)
J Surg Res
, vol.147
, pp. 1-8
-
-
Abe, R.1
Hirasawa, H.2
Oda, S.3
Sadahiro, T.4
Nakamura, M.5
-
26
-
-
0037461767
-
Inflammation: A nervous connection
-
Libert C (2003) Inflammation: A nervous connection. Nature 421: 328-329.
-
(2003)
Nature
, vol.421
, pp. 328-329
-
-
Libert, C.1
-
27
-
-
60549094934
-
In vivo profile of the human leukocyte microRNA response to endotoxemia
-
Schmidt WM, Spiel AO, Jilma B, Wolzt M, Müller M (2009) In vivo profile of the human leukocyte microRNA response to endotoxemia. Biochem Biophys Res Commun 380: 437-441.
-
(2009)
Biochem Biophys Res Commun
, vol.380
, pp. 437-441
-
-
Schmidt, W.M.1
Spiel, A.O.2
Jilma, B.3
Wolzt, M.4
Müller, M.5
-
28
-
-
34547941361
-
MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb
-
Xiao C, Calado DP, Galler G, Thai TH, Patterson HC, et al. (2007) MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell 131: 146-159.
-
(2007)
Cell
, vol.131
, pp. 146-159
-
-
Xiao, C.1
Calado, D.P.2
Galler, G.3
Thai, T.H.4
Patterson, H.C.5
-
29
-
-
58149218633
-
-
PLoS
-
Fredriksson K, Tjäder I, Keller P, Petrovic N, Ahlman B, et al. (2008) Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis-induced multiple organ failure. PLoS ONE 3: e3686.
-
(2008)
Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis-induced multiple organ failure
, vol.ONE 3
-
-
Fredriksson, K.1
Tjäder, I.2
Keller, P.3
Petrovic, N.4
Ahlman, B.5
-
30
-
-
60849102446
-
Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review
-
Minne L, Abu-Hanna A, de Jonge E (2008) Evaluation of SOFA-based models for predicting mortality in the ICU: A systematic review. Crit Care 12(6): R161.
-
(2008)
Crit Care
, vol.12
, Issue.6
-
-
Minne, L.1
Abu-Hanna, A.2
de Jonge, E.3
-
31
-
-
33750288937
-
Apoptosis and caspases regulate death and inflammation in sepsis
-
Hotchkiss RS, Nicholson DW (2006) Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 6: 813-822.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 813-822
-
-
Hotchkiss, R.S.1
Nicholson, D.W.2
-
32
-
-
0035338993
-
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans
-
Hotchkiss RS, Tinsley KW, Swanson PE, Schmieg Jr RE, Hui JJ, et al. (2001) Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans. J Immunol 166: 6952-6963.
-
(2001)
J Immunol
, vol.166
, pp. 6952-6963
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Schmieg Jr, R.E.4
Hui, J.J.5
-
33
-
-
0036499162
-
Depletion of dendritic cells, but not macrophages, in patients with sepsis
-
Hotchkiss RS, Tinsley KW, Swanson PE, Grayson MH, Osborne DF, et al. (2002) Depletion of dendritic cells, but not macrophages, in patients with sepsis. J Immunol 168: 2493-2500.
-
(2002)
J Immunol
, vol.168
, pp. 2493-2500
-
-
Hotchkiss, R.S.1
Tinsley, K.W.2
Swanson, P.E.3
Grayson, M.H.4
Osborne, D.F.5
-
34
-
-
47849125676
-
MicroRNAs: New regulators of immune cell development and function
-
Baltimore D, Boldin MP, O'Connell RM, Rao DS, Taganov KD (2008) MicroRNAs: new regulators of immune cell development and function. Nat Immunol 9: 839-845.
-
(2008)
Nat Immunol
, vol.9
, pp. 839-845
-
-
Baltimore, D.1
Boldin, M.P.2
O'Connell, R.M.3
Rao, D.S.4
Taganov, K.D.5
-
35
-
-
44449179366
-
Expression and function of micro-RNAs in immune cells during normal or disease state
-
Tili E, Michaille JJ, Calin GA (2008) Expression and function of micro-RNAs in immune cells during normal or disease state. Int J Med Sci 5: 73-79.
-
(2008)
Int J Med Sci
, vol.5
, pp. 73-79
-
-
Tili, E.1
Michaille, J.J.2
Calin, G.A.3
|