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Volumn 7, Issue 7, 2012, Pages

Angiopoietin-2 is a direct transcriptional target of tal1, lyl1 and lmo2 in endothelial cells

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 2; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; FIBROBLAST GROWTH FACTOR 2; INTERLEUKIN 3; LIM ONLY 2 PROTEIN; MESSENGER RNA; SMALL INTERFERING RNA; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR LYL1; TRANSCRIPTION FACTOR TAL1; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 84863707683     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040484     Document Type: Article
Times cited : (24)

References (55)
  • 1
    • 80052015813 scopus 로고    scopus 로고
    • Molecular control of endothelial cell behaviour during blood vessel morphogenesis
    • Herbert SP, Stainier DY, (2011) Molecular control of endothelial cell behaviour during blood vessel morphogenesis. Nat Rev Mol Cell Biol 12: 551-564.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 551-564
    • Herbert, S.P.1    Stainier, D.Y.2
  • 2
    • 77949895151 scopus 로고    scopus 로고
    • Haematopoietic stem cells derive directly from aortic endothelium during development
    • Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, et al. (2010) Haematopoietic stem cells derive directly from aortic endothelium during development. Nature 464: 108-111.
    • (2010) Nature , vol.464 , pp. 108-111
    • Bertrand, J.Y.1    Chi, N.C.2    Santoso, B.3    Teng, S.4    Stainier, D.Y.5
  • 3
    • 0031696447 scopus 로고    scopus 로고
    • Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny
    • Jaffredo T, Gautier R, Eichmann A, Dieterlen-Lievre F, (1998) Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development 125: 4575-4583.
    • (1998) Development , vol.125 , pp. 4575-4583
    • Jaffredo, T.1    Gautier, R.2    Eichmann, A.3    Dieterlen-Lievre, F.4
  • 4
  • 5
    • 33751558834 scopus 로고    scopus 로고
    • lyl-1 and tal-1/scl, two genes encoding closely related bHLH transcription factors, display highly overlapping expression patterns during cardiovascular and hematopoietic ontogeny
    • Giroux S, Kaushik AL, Capron C, Jalil A, Kelaidi C, et al. (2007) lyl-1 and tal-1/scl, two genes encoding closely related bHLH transcription factors, display highly overlapping expression patterns during cardiovascular and hematopoietic ontogeny. Gene Expr Patterns 7: 215-226.
    • (2007) Gene Expr Patterns , vol.7 , pp. 215-226
    • Giroux, S.1    Kaushik, A.L.2    Capron, C.3    Jalil, A.4    Kelaidi, C.5
  • 6
    • 0032584104 scopus 로고    scopus 로고
    • The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis
    • Yamada Y, Warren AJ, Dobson C, Forster A, Pannell R, et al. (1998) The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis. Proc Natl Acad Sci U S A 95: 3890-3895.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3890-3895
    • Yamada, Y.1    Warren, A.J.2    Dobson, C.3    Forster, A.4    Pannell, R.5
  • 7
    • 6044275816 scopus 로고    scopus 로고
    • SCL: from the origin of hematopoiesis to stem cells and leukemia
    • Lecuyer E, Hoang T, (2004) SCL: from the origin of hematopoiesis to stem cells and leukemia. Exp Hematol 32: 11-24.
    • (2004) Exp Hematol , vol.32 , pp. 11-24
    • Lecuyer, E.1    Hoang, T.2
  • 8
    • 0032520080 scopus 로고    scopus 로고
    • Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development
    • Visvader JE, Fujiwara Y, Orkin SH, (1998) Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development. Genes Dev 12: 473-479.
    • (1998) Genes Dev , vol.12 , pp. 473-479
    • Visvader, J.E.1    Fujiwara, Y.2    Orkin, S.H.3
  • 9
    • 0032722671 scopus 로고    scopus 로고
    • Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding
    • Porcher C, Liao EC, Fujiwara Y, Zon LI, Orkin SH, (1999) Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding. Development 126: 4603-4615.
    • (1999) Development , vol.126 , pp. 4603-4615
    • Porcher, C.1    Liao, E.C.2    Fujiwara, Y.3    Zon, L.I.4    Orkin, S.H.5
  • 10
    • 0346888544 scopus 로고    scopus 로고
    • Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1
    • Gering M, Yamada Y, Rabbitts TH, Patient RK, (2003) Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1. Development 130: 6187-6199.
    • (2003) Development , vol.130 , pp. 6187-6199
    • Gering, M.1    Yamada, Y.2    Rabbitts, T.H.3    Patient, R.K.4
  • 11
    • 18244392936 scopus 로고    scopus 로고
    • Scl is required for dorsal aorta as well as blood formation in zebrafish embryos
    • Patterson LJ, Gering M, Patient R, (2005) Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood 105: 3502-3511.
    • (2005) Blood , vol.105 , pp. 3502-3511
    • Patterson, L.J.1    Gering, M.2    Patient, R.3
  • 12
    • 0034602651 scopus 로고    scopus 로고
    • The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice
    • Yamada Y, Pannell R, Forster A, Rabbitts TH, (2000) The oncogenic LIM-only transcription factor Lmo2 regulates angiogenesis but not vasculogenesis in mice. Proc Natl Acad Sci U S A 97: 320-324.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 320-324
    • Yamada, Y.1    Pannell, R.2    Forster, A.3    Rabbitts, T.H.4
  • 13
    • 34147209078 scopus 로고    scopus 로고
    • TAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells
    • Deleuze V, Chalhoub E, El-Hajj R, Dohet C, Le Clech M, et al. (2007) TAL-1/SCL and its partners E47 and LMO2 up-regulate VE-cadherin expression in endothelial cells. Mol Cell Biol 27: 2687-2697.
    • (2007) Mol Cell Biol , vol.27 , pp. 2687-2697
    • Deleuze, V.1    Chalhoub, E.2    El-Hajj, R.3    Dohet, C.4    Le Clech, M.5
  • 14
    • 0034329320 scopus 로고    scopus 로고
    • Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development
    • Kappel A, Schlaeger TM, Flamme I, Orkin SH, Risau W, et al. (2000) Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development. Blood 96: 3078-3085.
    • (2000) Blood , vol.96 , pp. 3078-3085
    • Kappel, A.1    Schlaeger, T.M.2    Flamme, I.3    Orkin, S.H.4    Risau, W.5
  • 15
    • 4344694186 scopus 로고    scopus 로고
    • Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1
    • Schlaeger TM, Schuh A, Flitter S, Fisher A, Mikkola H, et al. (2004) Decoding hematopoietic specificity in the helix-loop-helix domain of the transcription factor SCL/Tal-1. Mol Cell Biol 24: 7491-7502.
    • (2004) Mol Cell Biol , vol.24 , pp. 7491-7502
    • Schlaeger, T.M.1    Schuh, A.2    Flitter, S.3    Fisher, A.4    Mikkola, H.5
  • 16
    • 33745079016 scopus 로고    scopus 로고
    • The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation
    • Capron C, Lecluse Y, Kaushik AL, Foudi A, Lacout C, et al. (2006) The SCL relative LYL-1 is required for fetal and adult hematopoietic stem cell function and B-cell differentiation. Blood 107: 4678-4686.
    • (2006) Blood , vol.107 , pp. 4678-4686
    • Capron, C.1    Lecluse, Y.2    Kaushik, A.L.3    Foudi, A.4    Lacout, C.5
  • 18
    • 67049108075 scopus 로고    scopus 로고
    • The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development
    • Wilson NK, Miranda-Saavedra D, Kinston S, Bonadies N, Foster SD, et al. (2009) The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development. Blood 113: 5456-5465.
    • (2009) Blood , vol.113 , pp. 5456-5465
    • Wilson, N.K.1    Miranda-Saavedra, D.2    Kinston, S.3    Bonadies, N.4    Foster, S.D.5
  • 19
    • 70449675049 scopus 로고    scopus 로고
    • Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy
    • Fujiwara T, O'Geen H, Keles S, Blahnik K, Linnemann AK, et al. (2009) Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy. Mol Cell 36: 667-681.
    • (2009) Mol Cell , vol.36 , pp. 667-681
    • Fujiwara, T.1    O'Geen, H.2    Keles, S.3    Blahnik, K.4    Linnemann, A.K.5
  • 20
    • 77955131763 scopus 로고    scopus 로고
    • Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells
    • Kassouf MT, Hughes JR, Taylor S, McGowan SJ, Soneji S, et al. (2010) Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells. Genome Res 20: 1064-1083.
    • (2010) Genome Res , vol.20 , pp. 1064-1083
    • Kassouf, M.T.1    Hughes, J.R.2    Taylor, S.3    McGowan, S.J.4    Soneji, S.5
  • 21
    • 77957348625 scopus 로고    scopus 로고
    • Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators
    • Wilson NK, Foster SD, Wang X, Knezevic K, Schutte J, et al. (2010) Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell 7: 532-544.
    • (2010) Cell Stem Cell , vol.7 , pp. 532-544
    • Wilson, N.K.1    Foster, S.D.2    Wang, X.3    Knezevic, K.4    Schutte, J.5
  • 22
    • 0028123474 scopus 로고
    • The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis
    • Kallianpur AR, Jordan JE, Brandt SJ, (1994) The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Blood 83: 1200-1208.
    • (1994) Blood , vol.83 , pp. 1200-1208
    • Kallianpur, A.R.1    Jordan, J.E.2    Brandt, S.J.3
  • 25
    • 33747890790 scopus 로고    scopus 로고
    • Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes
    • Tang T, Shi Y, Opalenik SR, Brantley-Sieders DM, Chen J, et al. (2006) Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes. J Pathol 210: 121-129.
    • (2006) J Pathol , vol.210 , pp. 121-129
    • Tang, T.1    Shi, Y.2    Opalenik, S.R.3    Brantley-Sieders, D.M.4    Chen, J.5
  • 26
    • 77954676266 scopus 로고    scopus 로고
    • LYL1 activity is required for the maturation of newly formed blood vessels in adulthood
    • Pirot N, Deleuze V, El-Hajj R, Dohet C, Sablitzky F, et al. (2010) LYL1 activity is required for the maturation of newly formed blood vessels in adulthood. Blood 115: 5270-5279.
    • (2010) Blood , vol.115 , pp. 5270-5279
    • Pirot, N.1    Deleuze, V.2    El-Hajj, R.3    Dohet, C.4    Sablitzky, F.5
  • 27
    • 1842531473 scopus 로고    scopus 로고
    • The bHLH TAL-1/SCL regulates endothelial cell migration and morphogenesis
    • Lazrak M, Deleuze V, Noel D, Haouzi D, Chalhoub E, et al. (2004) The bHLH TAL-1/SCL regulates endothelial cell migration and morphogenesis. J Cell Sci 117: 1161-1171.
    • (2004) J Cell Sci , vol.117 , pp. 1161-1171
    • Lazrak, M.1    Deleuze, V.2    Noel, D.3    Haouzi, D.4    Chalhoub, E.5
  • 28
    • 0037148909 scopus 로고    scopus 로고
    • The LIM-domain protein Lmo2 is a key regulator of tumour angiogenesis: a new anti-angiogenesis drug target
    • Yamada Y, Pannell R, Forster A, Rabbitts TH, (2002) The LIM-domain protein Lmo2 is a key regulator of tumour angiogenesis: a new anti-angiogenesis drug target. Oncogene 21: 1309-1315.
    • (2002) Oncogene , vol.21 , pp. 1309-1315
    • Yamada, Y.1    Pannell, R.2    Forster, A.3    Rabbitts, T.H.4
  • 29
    • 58849151863 scopus 로고    scopus 로고
    • The transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms and selected other entities
    • Gratzinger D, Zhao S, West R, Rouse RV, Vogel H, et al. (2009) The transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms and selected other entities. Am J Clin Pathol 131: 264-278.
    • (2009) Am J Clin Pathol , vol.131 , pp. 264-278
    • Gratzinger, D.1    Zhao, S.2    West, R.3    Rouse, R.V.4    Vogel, H.5
  • 30
    • 33846159467 scopus 로고    scopus 로고
    • Novel binding partners of Ldb1 are required for haematopoietic development
    • Meier N, Krpic S, Rodriguez P, Strouboulis J, Monti M, et al. (2006) Novel binding partners of Ldb1 are required for haematopoietic development. Development 133: 4913-4923.
    • (2006) Development , vol.133 , pp. 4913-4923
    • Meier, N.1    Krpic, S.2    Rodriguez, P.3    Strouboulis, J.4    Monti, M.5
  • 31
    • 0026677532 scopus 로고
    • HMEC-1: establishment of an immortalized human microvascular endothelial cell line
    • Ades EW, Candal FJ, Swerlick RA, George VG, Summers S, et al. (1992) HMEC-1: establishment of an immortalized human microvascular endothelial cell line. J Invest Dermatol 99: 683-690.
    • (1992) J Invest Dermatol , vol.99 , pp. 683-690
    • Ades, E.W.1    Candal, F.J.2    Swerlick, R.A.3    George, V.G.4    Summers, S.5
  • 32
    • 52049114102 scopus 로고    scopus 로고
    • In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis
    • Koh W, Stratman AN, Sacharidou A, Davis GE, (2008) In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis. Methods Enzymol 443: 83-101.
    • (2008) Methods Enzymol , vol.443 , pp. 83-101
    • Koh, W.1    Stratman, A.N.2    Sacharidou, A.3    Davis, G.E.4
  • 33
    • 60749096085 scopus 로고    scopus 로고
    • Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system
    • Augustin HG, Koh GY, Thurston G, Alitalo K, (2009) Control of vascular morphogenesis and homeostasis through the angiopoietin-Tie system. Nat Rev Mol Cell Biol 10: 165-177.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 165-177
    • Augustin, H.G.1    Koh, G.Y.2    Thurston, G.3    Alitalo, K.4
  • 34
    • 2542453735 scopus 로고    scopus 로고
    • The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies
    • Fiedler U, Scharpfenecker M, Koidl S, Hegen A, Grunow V, et al. (2004) The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies. Blood 103: 4150-4156.
    • (2004) Blood , vol.103 , pp. 4150-4156
    • Fiedler, U.1    Scharpfenecker, M.2    Koidl, S.3    Hegen, A.4    Grunow, V.5
  • 35
    • 61549130907 scopus 로고    scopus 로고
    • Angiopoietin-2 exocytosis is stimulated by sphingosine-1-phosphate in human blood and lymphatic endothelial cells
    • Jang C, Koh YJ, Lim NK, Kang HJ, Kim DH, et al. (2009) Angiopoietin-2 exocytosis is stimulated by sphingosine-1-phosphate in human blood and lymphatic endothelial cells. Arterioscler Thromb Vasc Biol 29: 401-407.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 401-407
    • Jang, C.1    Koh, Y.J.2    Lim, N.K.3    Kang, H.J.4    Kim, D.H.5
  • 36
    • 54049146968 scopus 로고    scopus 로고
    • The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1
    • Simon MP, Tournaire R, Pouyssegur J, (2008) The angiopoietin-2 gene of endothelial cells is up-regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA-2 and Ets-1. J Cell Physiol 217: 809-818.
    • (2008) J Cell Physiol , vol.217 , pp. 809-818
    • Simon, M.P.1    Tournaire, R.2    Pouyssegur, J.3
  • 37
    • 0028040256 scopus 로고
    • Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins
    • Hsu HL, Huang L, Tsan JT, Funk W, Wright WE, et al. (1994) Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins. Mol Cell Biol 14: 1256-1265.
    • (1994) Mol Cell Biol , vol.14 , pp. 1256-1265
    • Hsu, H.L.1    Huang, L.2    Tsan, J.T.3    Funk, W.4    Wright, W.E.5
  • 38
    • 0029913351 scopus 로고    scopus 로고
    • Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells
    • Miyamoto A, Cui X, Naumovski L, Cleary ML, (1996) Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells. Mol Cell Biol 16: 2394-2401.
    • (1996) Mol Cell Biol , vol.16 , pp. 2394-2401
    • Miyamoto, A.1    Cui, X.2    Naumovski, L.3    Cleary, M.L.4
  • 39
    • 36349025387 scopus 로고    scopus 로고
    • Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction
    • Lecuyer E, Lariviere S, Sincennes MC, Haman A, Lahlil R, et al. (2007) Protein stability and transcription factor complex assembly determined by the SCL-LMO2 interaction. J Biol Chem 282: 33649-33658.
    • (2007) J Biol Chem , vol.282 , pp. 33649-33658
    • Lecuyer, E.1    Lariviere, S.2    Sincennes, M.C.3    Haman, A.4    Lahlil, R.5
  • 40
    • 79953828409 scopus 로고    scopus 로고
    • VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines
    • Stratman AN, Davis MJ, Davis GE, (2011) VEGF and FGF prime vascular tube morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood 117: 3709-3719.
    • (2011) Blood , vol.117 , pp. 3709-3719
    • Stratman, A.N.1    Davis, M.J.2    Davis, G.E.3
  • 41
    • 5344244722 scopus 로고    scopus 로고
    • Expression of angiopoietin-2 in endothelial cells is controlled by positive and negative regulatory promoter elements
    • Hegen A, Koidl S, Weindel K, Marme D, Augustin HG, et al. (2004) Expression of angiopoietin-2 in endothelial cells is controlled by positive and negative regulatory promoter elements. Arterioscler Thromb Vasc Biol 24: 1803-1809.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1803-1809
    • Hegen, A.1    Koidl, S.2    Weindel, K.3    Marme, D.4    Augustin, H.G.5
  • 42
    • 1842478183 scopus 로고    scopus 로고
    • Hypoxic regulation of angiopoietin-2 expression in endothelial cells
    • Pichiule P, Chavez JC, LaManna JC, (2004) Hypoxic regulation of angiopoietin-2 expression in endothelial cells. J Biol Chem 279: 12171-12180.
    • (2004) J Biol Chem , vol.279 , pp. 12171-12180
    • Pichiule, P.1    Chavez, J.C.2    LaManna, J.C.3
  • 43
    • 33750349223 scopus 로고    scopus 로고
    • Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells
    • Daly C, Pasnikowski E, Burova E, Wong V, Aldrich TH, et al. (2006) Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells. Proc Natl Acad Sci U S A 103: 15491-15496.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15491-15496
    • Daly, C.1    Pasnikowski, E.2    Burova, E.3    Wong, V.4    Aldrich, T.H.5
  • 44
    • 35649026775 scopus 로고    scopus 로고
    • High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A
    • Yao D, Taguchi T, Matsumura T, Pestell R, Edelstein D, et al. (2007) High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. J Biol Chem 282: 31038-31045.
    • (2007) J Biol Chem , vol.282 , pp. 31038-31045
    • Yao, D.1    Taguchi, T.2    Matsumura, T.3    Pestell, R.4    Edelstein, D.5
  • 45
    • 51649130774 scopus 로고    scopus 로고
    • Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
    • Kassouf MT, Chagraoui H, Vyas P, Porcher C, (2008) Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis. Blood 112: 1056-1067.
    • (2008) Blood , vol.112 , pp. 1056-1067
    • Kassouf, M.T.1    Chagraoui, H.2    Vyas, P.3    Porcher, C.4
  • 46
    • 55449130784 scopus 로고    scopus 로고
    • Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis
    • Wozniak RJ, Keles S, Lugus JJ, Young KH, Boyer ME, et al. (2008) Molecular hallmarks of endogenous chromatin complexes containing master regulators of hematopoiesis. Mol Cell Biol 28: 6681-6694.
    • (2008) Mol Cell Biol , vol.28 , pp. 6681-6694
    • Wozniak, R.J.1    Keles, S.2    Lugus, J.J.3    Young, K.H.4    Boyer, M.E.5
  • 47
    • 64049118936 scopus 로고    scopus 로고
    • SCL and associated proteins distinguish active from repressive GATA transcription factor complexes
    • Tripic T, Deng W, Cheng Y, Zhang Y, Vakoc CR, et al. (2009) SCL and associated proteins distinguish active from repressive GATA transcription factor complexes. Blood 113: 2191-2201.
    • (2009) Blood , vol.113 , pp. 2191-2201
    • Tripic, T.1    Deng, W.2    Cheng, Y.3    Zhang, Y.4    Vakoc, C.R.5
  • 48
    • 79960051861 scopus 로고    scopus 로고
    • Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression
    • Kanki Y, Kohro T, Jiang S, Tsutsumi S, Mimura I, et al. (2011) Epigenetically coordinated GATA2 binding is necessary for endothelium-specific endomucin expression. Embo J 30: 2582-2595.
    • (2011) Embo J , vol.30 , pp. 2582-2595
    • Kanki, Y.1    Kohro, T.2    Jiang, S.3    Tsutsumi, S.4    Mimura, I.5
  • 50
    • 84863649033 scopus 로고    scopus 로고
    • Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies
    • Bresnick EH, Katsumura KR, Lee HY, Johnson KD, Perkins AS, (2012) Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res.
    • (2012) Nucleic Acids Res
    • Bresnick, E.H.1    Katsumura, K.R.2    Lee, H.Y.3    Johnson, K.D.4    Perkins, A.S.5
  • 51
    • 79951831250 scopus 로고    scopus 로고
    • Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex
    • El Omari K, Hoosdally SJ, Tuladhar K, Karia D, Vyas P, et al. (2011) Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex. Blood 117: 2146-2156.
    • (2011) Blood , vol.117 , pp. 2146-2156
    • El Omari, K.1    Hoosdally, S.J.2    Tuladhar, K.3    Karia, D.4    Vyas, P.5
  • 52
    • 59649092177 scopus 로고    scopus 로고
    • The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications
    • Dejana E, Tournier-Lasserve E, Weinstein BM, (2009) The control of vascular integrity by endothelial cell junctions: molecular basis and pathological implications. Dev Cell 16: 209-221.
    • (2009) Dev Cell , vol.16 , pp. 209-221
    • Dejana, E.1    Tournier-Lasserve, E.2    Weinstein, B.M.3
  • 53
    • 77954369555 scopus 로고    scopus 로고
    • Angiopoietin-2 Regulates Gene Expression in TIE2-Expressing Monocytes and Augments Their Inherent Proangiogenic Functions
    • Coffelt SB, Tal AO, Scholz A, De Palma M, Patel S, et al. (2010) Angiopoietin-2 Regulates Gene Expression in TIE2-Expressing Monocytes and Augments Their Inherent Proangiogenic Functions. Cancer Res 70.
    • (2010) Cancer Res , vol.70
    • Coffelt, S.B.1    Tal, A.O.2    Scholz, A.3    de Palma, M.4    Patel, S.5
  • 54
    • 79953740905 scopus 로고    scopus 로고
    • Multiple effects of angiopoietin-2 blockade on tumors
    • Lewis CE, Ferrara N, (2011) Multiple effects of angiopoietin-2 blockade on tumors. Cancer Cell 19: 431-433.
    • (2011) Cancer Cell , vol.19 , pp. 431-433
    • Lewis, C.E.1    Ferrara, N.2
  • 55
    • 79953750307 scopus 로고    scopus 로고
    • Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells
    • Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A, et al. (2011) Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer Cell 19: 512-526.
    • (2011) Cancer Cell , vol.19 , pp. 512-526
    • Mazzieri, R.1    Pucci, F.2    Moi, D.3    Zonari, E.4    Ranghetti, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.