Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 52, 2013, Pages 21065-21070

  Dettman, Jeremy R ^a,b   Rodrigue, Nicolas ^c   Aaron, Shawn D ^d   Kassen, Rees ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF CALGARY   (Canada)

^d OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

Multidrug resistance; Redox balance; Virulence

Indexed keywords

ANTIBIOTIC AGENT; CEFTAZIDIME; CIPROFLOXACIN; GENTAMICIN; HEAVY METAL;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENOME; BACTERIAL METABOLISM; BACTERIAL SECRETION SYSTEM; BACTERIAL STRAIN; BACTERIUM ISOLATION; BIOFILM; BIOLOGICAL FUNCTIONS; CELL SPREADING; CONTROLLED STUDY; CYSTIC FIBROSIS; DRUG METABOLISM; ENRICHMENT CULTURE; EPIDEMIC; EVOLUTIONARY ADAPTATION; GENE SEQUENCE; GENETIC POLYMORPHISM; GENOTYPE; LUNG FIBROSIS; NONHUMAN; NORTH AMERICA; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PHYLOGENY; POPULATION STRUCTURE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; REDUCTION; RESPIRATORY TRACT INFECTION; SEQUENCE ALIGNMENT; UNITED KINGDOM;

EID: 84891362153     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1307862110     Document Type: Article

References (43)

1. Aaron SD, et al. (2010) Infection with transmissible strains of Pseudomonas aeruginosa and clinical outcomes in adults with cystic fibrosis. JAMA 304(19): 2145-2153.
2. LiPuma JJ (2010) The changing microbial epidemiology in cystic fibrosis. Clin Microbiol Rev 23(2): 299-323.
3. Hauser AR, Jain M, Bar-Meir M, McColley SA (2011) Clinical significance of microbial infection and adaptation in cystic fibrosis. Clin Microbiol Rev 24(1): 29-70.
4. Folkesson A, et al. (2012) Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: An evolutionary perspective. Nat Rev Microbiol 10(12): 841-851.
5. Sriramulu DD, Lünsdorf H, Lam JS, Römling U (2005) Microcolony formation: A novel biofilm model of Pseudomonas aeruginosa for the cystic fibrosis lung. J Med Microbiol 54(Pt 7): 667-676.
6. Smith EE, et al. (2006) Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc Natl Acad Sci USA 103(22): 8487-8492.
7. Poole K (2005) Efflux-mediated antimicrobial resistance. J Antimicrob Chemother 56(1): 20-51.
8. Cramer N, et al. (2011) Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs. Environ Microbiol 13(7): 1690-1704.
9. Yang L, et al. (2011) Evolutionary dynamics of bacteria in a human host environment. Proc Natl Acad Sci USA 108(18): 7481-7486.
10. Mowat E, et al. (2011) Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections. Am J Respir Crit Care Med 183(12): 1674-1679.
11. Al-Aloul M, et al. (2004) Increased morbidity associated with chronic infection by an epidemic Pseudomonas aeruginosa strain in CF patients. Thorax 59(4): 334-336.
12. Pirnay JP, et al. (2009) Pseudomonas aeruginosa population structure revisited. PLoS ONE 4(11):e7740.
13. Takase H, Nitanai H, Hoshino K, Otani T (2000) Impact of siderophore production on Pseudomonas aeruginosa infections in immunosuppressed mice. Infect Immun 68(4): 1834-1839.
14. Smith EE, Sims EH, Spencer DH, Kaul R, Olson MV (2005) Evidence for diversifying selection at the pyoverdine locus of Pseudomonas aeruginosa. J Bacteriol 187(6): 2138-2147.
15. Raymond CK, et al. (2002) Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa. J Bacteriol 184(13): 3614-3622.
16. Jolley KA, Maiden MCJ (2010) BIGSdb: Scalable analysis of bacterial genome variation at the population level. BMC Bioinformatics 11:595.
17. Marttinen P, et al. (2012) Detection of recombination events in bacterial genomes from large population samples. Nucleic Acids Res 40(1):e6.
18. Dettman JR, et al. (2012) Evolutionary insight from whole-genome sequencing of experimentally evolved microbes. Mol Ecol 21(9): 2058-2077.
19. Winstanley C, et al. (2009) Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa. Genome Res 19(1): 12-23.
20. Hauser AR (2009) The type III secretion system of Pseudomonas aeruginosa: Infection by injection. Nat Rev Microbiol 7(9): 654-665.
21. Schmiel DH, Miller VL (1999) Bacterial phospholipases and pathogenesis. Microbes Infect 1(13): 1103-1112.
22. Beaudoin T, Zhang L, Hinz AJ, Parr CJ, Mah TF (2012) The biofilm-specific antibiotic resistance gene ndvB is important for expression of ethanol oxidation genes in Pseudomonas aeruginosa biofilms. J Bacteriol 194(12): 3128-3136.
23. Jackson RW, Vinatzer B, Arnold DL, Dorus S, Murillo J (2011) The influence of the accessory genome on bacterial pathogen evolution. Mobile Genet Elements 1(1): 55-65.
24. MacMicking J, Xie QW, Nathan C (1997) Nitric oxide and macrophage function. Annu Rev Immunol 15: 323-350.
25. Roum JH, Buhl R, McElvaney NG, Borok Z, Crystal RG (1993) Systemic deficiency of glutathione in cystic fibrosis. J Appl Physiol (1985) 75(6): 2419-2424.
26. Schobert M, Jahn D (2010) Anaerobic physiology of Pseudomonas aeruginosa in the cystic fibrosis lung. Int J Med Microbiol 300(8): 549-556.
27. Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ (2007) A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130(5): 797-810.
28. Liu Y, Imlay JA (2013) Cell death from antibiotics without the involvement of reactive oxygen species. Science 339(6124): 1210-1213.
29. Gusarov I, Shatalin K, Starodubtseva M, Nudler E (2009) Endogenous nitric oxide protects bacteria against a wide spectrum of antibiotics. Science 325(5946): 1380-1384.
30. McCallum SJ, et al. (2001) Superinfection with a transmissible strain of Pseudomonas aeruginosa in adults with cystic fibrosis chronically colonised by P aeruginosa. Lancet 358(9281): 558-560.
31. Salunkhe P, et al. (2005) A cystic fibrosis epidemic strain of Pseudomonas aeruginosa displays enhanced virulence and antimicrobial resistance. J Bacteriol 187(14): 4908-4920.
32. Beaudoin T, Aaron SD, Giesbrecht-Lewis T, Vandemheen K, Mah TF (2010) Characterization of clonal strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients in Ontario, Canada. Can J Microbiol 56(7): 548-557.
33. Carter MEK, et al. (2010) A subtype of a Pseudomonas aeruginosa cystic fibrosis epidemic strain exhibits enhanced virulence in a murine model of acute respiratory infection. J Infect Dis 202(6): 935-942.
34. Shafikhani SH, Engel J (2006) Pseudomonas aeruginosa type III-secreted toxin ExoT inhibits host-cell division by targeting cytokinesis at multiple steps. Proc Natl Acad Sci USA 103(42): 15605-15610.
35. Hoboth C, et al. (2009) Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis. J Infect Dis 200(1): 118-130.
36. Palmer KL, Aye LM, Whiteley M (2007) Nutritional cues control Pseudomonas aeruginosa multicellular behavior in cystic fibrosis sputum. J Bacteriol 189(22): 8079-8087.
37. Regunathan S, Piletz JE (2003) Regulation of inducible nitric oxide synthase and agmatine synthesis in macrophages and astrocytes. Ann N Y Acad Sci 1009: 20-29.
38. Grasemann H, et al. (2012) L-ornithine derived polyamines in cystic fibrosis airways. PLoS ONE 7(10):e46618.
39. Saier MH, Jr., et al. (1998) Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria. FASEB J 12(3): 265-274.
40. Armstrong DS, et al. (2002) Detection of a widespread clone of Pseudomonas aeruginosa in a pediatric cystic fibrosis clinic. Am J Respir Crit Care Med 166(7): 983-987.
41. Hill D, et al. (2005) Antibiotic susceptabilities of Pseudomonas aeruginosa isolates derived from patients with cystic fibrosis under aerobic, anaerobic, and biofilm conditions. J Clin Microbiol 43(10): 5085-5090.
42. Chen H, et al. (2008) The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism. Proc Natl Acad Sci USA 105(36): 13586-13591.
43. Lieberman TD, et al. (2011) Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. Nat Genet 43(12): 1275-1280.