Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR

Genome Biology

Volumn 16, Issue 1, 2015, Pages

  Li, Wei ^a,b   Köster, Johannes ^a,b   Xu, Han ^c   Chen, Chen Hao ^a,b   Xiao, Tengfei ^b   Liu, Jun S ^d   Brown, Myles ^b,e   Liu, X Shirley ^a,b,f  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d HARVARD UNIVERSITY   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f TONGJI UNIVERSITY   (China)

Author keywords

CRISPR Cas9; D3; Data driven documents; Expectation Maximization; Maximum likelihood; Negative binomial; Quality contro; Screening; Visualization

Indexed keywords

CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; ESSENTIAL GENE; EXPECTATION; FUNCTIONAL GENOMICS; GENE DISRUPTION; KNOCKOUT GENE; MAXIMUM LIKELIHOOD METHOD; MODEL; QUALITY CONTROL; STATISTICAL MODEL; WORKFLOW; CRISPR CAS SYSTEM; GENE TARGETING; PROCEDURES; SOFTWARE; STANDARDS;

CRISPR-CAS SYSTEMS; GENE TARGETING; GENES, ESSENTIAL; QUALITY CONTROL; SOFTWARE;

EID: 84955629629     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0843-6     Document Type: Article

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