Nimbolide inhibits pancreatic cancer growth and metastasis through ROS-mediated apoptosis and inhibition of epithelial-to-mesenchymal transition

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Subramani, Ramadevi ^a   Gonzalez, Elizabeth ^a   Arumugam, Arunkumar ^a   Nandy, Sushmita ^a   Gonzalez, Viviana ^b   Medel, Joshua ^a   Camacho, Fernando ^a   Ortega, Andrew ^b   Bonkoungou, Sandrine ^a   Narayan, Mahesh ^b   Dwivedi, Alok Kumar ^a   Lakshmanaswamy, Rajkumar ^a  

^a TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF TEXAS AT EL PASO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3-METHYLADENINE; ADENINE; LIMONOID; NIMBOLIDE; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE;

ANALOGS AND DERIVATIVES; APOPTOSIS; AUTOPHAGY; CELL PROLIFERATION; DRUG EFFECTS; EPITHELIAL MESENCHYMAL TRANSITION; GENETICS; HUMAN; METABOLISM; METASTASIS; PANCREATIC NEOPLASMS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ADENINE; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; LIMONINS; MAP KINASE SIGNALING SYSTEM; NEOPLASM METASTASIS; PANCREATIC NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; REACTIVE OXYGEN SPECIES;

EID: 84955513541     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep19819     Document Type: Article

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