메뉴 건너뛰기




Volumn 35, Issue 3, 2016, Pages 344-357

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; HORMONE RECEPTOR; MATRIX METALLOPROTEINASE 14; PROGESTERONE RECEPTOR; PROTEIN P63; CKAP4 PROTEIN, HUMAN; INTERSTITIAL COLLAGENASE; MEMBRANE PROTEIN;

EID: 84955383716     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.87     Document Type: Article
Times cited : (74)

References (59)
  • 1
    • 0037805549 scopus 로고    scopus 로고
    • Basement membranes: Structure, assembly and role in tumour angiogenesis
    • Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 2003; 3: 422-433.
    • (2003) Nat Rev Cancer , vol.3 , pp. 422-433
    • Kalluri, R.1
  • 2
    • 84884286419 scopus 로고    scopus 로고
    • Progression from ductal carcinoma in situ to invasive breast cancer: Revisited
    • Cowell CF, Weigelt B, Sakr RA, Ng CK, Hicks J, King TA et al. Progression from ductal carcinoma in situ to invasive breast cancer: revisited. Mol Oncol 2013; 7: 859-869.
    • (2013) Mol Oncol , vol.7 , pp. 859-869
    • Cowell, C.F.1    Weigelt, B.2    Sakr, R.A.3    Ng, C.K.4    Hicks, J.5    King, T.A.6
  • 3
    • 0028291737 scopus 로고
    • A matrix metalloproteinase expressed on the surface of invasive tumour cells
    • Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E et al. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 1994; 370: 61-65.
    • (1994) Nature , vol.370 , pp. 61-65
    • Sato, H.1    Takino, T.2    Okada, Y.3    Cao, J.4    Shinagawa, A.5    Yamamoto, E.6
  • 4
    • 0029753004 scopus 로고    scopus 로고
    • Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay
    • Tsunezuka Y, Kinoh H, Takino T, Watanabe Y, Okada Y, Shinagawa A et al. Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay. Cancer Res 1996; 56: 5678-5683.
    • (1996) Cancer Res , vol.56 , pp. 5678-5683
    • Tsunezuka, Y.1    Kinoh, H.2    Takino, T.3    Watanabe, Y.4    Okada, Y.5    Shinagawa, A.6
  • 5
    • 0038784546 scopus 로고    scopus 로고
    • Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix
    • Hotary KB, Allen ED, Brooks PC, Datta NS, Long MW, Weiss SJ. Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. Cell 2003; 114: 33-45.
    • (2003) Cell , vol.114 , pp. 33-45
    • Hotary, K.B.1    Allen, E.D.2    Brooks, P.C.3    Datta, N.S.4    Long, M.W.5    Weiss, S.J.6
  • 6
    • 44349156127 scopus 로고    scopus 로고
    • MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease
    • Szabova L, Chrysovergis K, Yamada SS, Holmbeck K. MT1-MMP is required for efficient tumor dissemination in experimental metastatic disease. Oncogene 2008; 27: 3274-3281.
    • (2008) Oncogene , vol.27 , pp. 3274-3281
    • Szabova, L.1    Chrysovergis, K.2    Yamada, S.S.3    Holmbeck, K.4
  • 7
    • 79959904515 scopus 로고    scopus 로고
    • Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors
    • Perentes JY, Kirkpatrick ND, Nagano S, Smith EY, Shaver CM, Sgroi D et al. Cancer cell-associated MT1-MMP promotes blood vessel invasion and distant metastasis in triple-negative mammary tumors. Cancer Res 2011; 71: 4527-4538.
    • (2011) Cancer Res , vol.71 , pp. 4527-4538
    • Perentes, J.Y.1    Kirkpatrick, N.D.2    Nagano, S.3    Smith, E.Y.4    Shaver, C.M.5    Sgroi, D.6
  • 8
    • 9444290419 scopus 로고    scopus 로고
    • Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP
    • Sabeh F, Ota I, Holmbeck K, Birkedal-Hansen H, Soloway P, Balbin M et al. Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP. J Cell Biol 2004; 167: 769-781.
    • (2004) J Cell Biol , vol.167 , pp. 769-781
    • Sabeh, F.1    Ota, I.2    Holmbeck, K.3    Birkedal-Hansen, H.4    Soloway, P.5    Balbin, M.6
  • 9
    • 33749350351 scopus 로고    scopus 로고
    • A cancer cell metalloprotease triad regulates the basement membrane transmigration program
    • Hotary K, Li XY, Allen E, Stevens SL, Weiss SJ. A cancer cell metalloprotease triad regulates the basement membrane transmigration program. Genes Dev 2006; 20: 2673-2686.
    • (2006) Genes Dev , vol.20 , pp. 2673-2686
    • Hotary, K.1    Li, X.Y.2    Allen, E.3    Stevens, S.L.4    Weiss, S.J.5
  • 10
    • 34547569807 scopus 로고    scopus 로고
    • Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
    • Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C et al. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol 2007; 9: 893-904.
    • (2007) Nat Cell Biol , vol.9 , pp. 893-904
    • Wolf, K.1    Wu, Y.I.2    Liu, Y.3    Geiger, J.4    Tam, E.5    Overall, C.6
  • 12
    • 0028935326 scopus 로고
    • Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas
    • Okada A, Bellocq JP, Rouyer N, Chenard MP, Rio MC, Chambon P et al. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc Natl Acad Sci USA 1995; 92: 2730-2734.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 2730-2734
    • Okada, A.1    Bellocq, J.P.2    Rouyer, N.3    Chenard, M.P.4    Rio, M.C.5    Chambon, P.6
  • 13
    • 0032959030 scopus 로고    scopus 로고
    • Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors
    • Nakada M, Nakamura H, Ikeda E, Fujimoto N, Yamashita J, Sato H et al. Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human astrocytic tumors. Am J Pathol 1999; 154: 417-428.
    • (1999) Am J Pathol , vol.154 , pp. 417-428
    • Nakada, M.1    Nakamura, H.2    Ikeda, E.3    Fujimoto, N.4    Yamashita, J.5    Sato, H.6
  • 14
    • 0032953789 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinase-1 expression and activation of gelatinase A as prognostic markers in advanced pediatric neuroblastoma
    • Sakakibara M, Koizumi S, Saikawa Y, Wada H, Ichihara T, Sato H et al. Membrane-type matrix metalloproteinase-1 expression and activation of gelatinase A as prognostic markers in advanced pediatric neuroblastoma. Cancer 1999; 85: 231-239.
    • (1999) Cancer , vol.85 , pp. 231-239
    • Sakakibara, M.1    Koizumi, S.2    Saikawa, Y.3    Wada, H.4    Ichihara, T.5    Sato, H.6
  • 15
    • 23044466812 scopus 로고    scopus 로고
    • Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion
    • Zhai Y, Hotary KB, Nan B, Bosch FX, Munoz N, Weiss SJ et al. Expression of membrane type 1 matrix metalloproteinase is associated with cervical carcinoma progression and invasion. Cancer Res 2005; 65: 6543-6550.
    • (2005) Cancer Res , vol.65 , pp. 6543-6550
    • Zhai, Y.1    Hotary, K.B.2    Nan, B.3    Bosch, F.X.4    Munoz, N.5    Weiss, S.J.6
  • 16
    • 0030951910 scopus 로고    scopus 로고
    • Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas
    • Ueno H, Nakamura H, Inoue M, Imai K, Noguchi M, Sato H et al. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res 1997; 57: 2055-2060.
    • (1997) Cancer Res , vol.57 , pp. 2055-2060
    • Ueno, H.1    Nakamura, H.2    Inoue, M.3    Imai, K.4    Noguchi, M.5    Sato, H.6
  • 17
    • 0032835899 scopus 로고    scopus 로고
    • Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas
    • Jones JL, Glynn P, Walker RA. Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas. J Pathol 1999; 189: 161-168.
    • (1999) J Pathol , vol.189 , pp. 161-168
    • Jones, J.L.1    Glynn, P.2    Walker, R.A.3
  • 18
    • 0037457657 scopus 로고    scopus 로고
    • Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells
    • Bisson C, Blacher S, Polette M, Blanc JF, Kebers F, Desreux J et al. Restricted expression of membrane type 1-matrix metalloproteinase by myofibroblasts adjacent to human breast cancer cells. Int J Cancer 2003; 105: 7-13.
    • (2003) Int J Cancer , vol.105 , pp. 7-13
    • Bisson, C.1    Blacher, S.2    Polette, M.3    Blanc, J.F.4    Kebers, F.5    Desreux, J.6
  • 20
    • 77955271694 scopus 로고    scopus 로고
    • Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer
    • Muggerud AA, Hallett M, Johnsen H, Kleivi K, Zhou W, Tahmasebpoor S et al. Molecular diversity in ductal carcinoma in situ (DCIS) and early invasive breast cancer. Mol Oncol 2010; 4: 357-368.
    • (2010) Mol Oncol , vol.4 , pp. 357-368
    • Muggerud, A.A.1    Hallett, M.2    Johnsen, H.3    Kleivi, K.4    Zhou, W.5    Tahmasebpoor, S.6
  • 21
    • 84865773617 scopus 로고    scopus 로고
    • Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer
    • Lee S, Stewart S, Nagtegaal I, Luo J, Wu Y, Colditz G et al. Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer. Cancer Res 2012; 72: 4574-4586.
    • (2012) Cancer Res , vol.72 , pp. 4574-4586
    • Lee, S.1    Stewart, S.2    Nagtegaal, I.3    Luo, J.4    Wu, Y.5    Colditz, G.6
  • 22
    • 84894581126 scopus 로고    scopus 로고
    • Collective invasion in breast cancer requires a conserved basal epithelial program
    • Cheung KJ, Gabrielson E, Werb Z, Ewald AJ. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell 2013; 155: 1639-1651.
    • (2013) Cell , vol.155 , pp. 1639-1651
    • Cheung, K.J.1    Gabrielson, E.2    Werb, Z.3    Ewald, A.J.4
  • 23
    • 33747095513 scopus 로고    scopus 로고
    • Do myoepithelial cells hold the key for breast tumor progression?
    • Polyak K, Hu M. Do myoepithelial cells hold the key for breast tumor progression? J Mammary Gland Biol Neoplasia 2005; 10: 231-247.
    • (2005) J Mammary Gland Biol Neoplasia , vol.10 , pp. 231-247
    • Polyak, K.1    Hu, M.2
  • 25
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999; 398: 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 26
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999; 398: 714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3    Kaghad, M.4    Walker, N.5    Bronson, R.T.6
  • 28
    • 84867867576 scopus 로고    scopus 로고
    • Quantification of PKC family genes in sporadic breast cancer by qRT-PCR: Evidence that PKCiota/lambda overexpression is an independent prognostic factor
    • Awadelkarim KD, Callens C, Rosse C, Susini A, Vacher S, Rouleau E et al. Quantification of PKC family genes in sporadic breast cancer by qRT-PCR: Evidence that PKCiota/lambda overexpression is an independent prognostic factor. Int J Cancer 2012; 131: 2852-2862.
    • (2012) Int J Cancer , vol.131 , pp. 2852-2862
    • Awadelkarim, K.D.1    Callens, C.2    Rosse, C.3    Susini, A.4    Vacher, S.5    Rouleau, E.6
  • 29
    • 77449153440 scopus 로고    scopus 로고
    • An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ
    • Behbod F, Kittrell FS, LaMarca H, Edwards D, Kerbawy S, Heestand JC et al. An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res 2009; 11: R66.
    • (2009) Breast Cancer Res , vol.11 , pp. R66
    • Behbod, F.1    Kittrell, F.S.2    LaMarca, H.3    Edwards, D.4    Kerbawy, S.5    Heestand, J.C.6
  • 30
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10: 515-527.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 31
    • 0037377761 scopus 로고    scopus 로고
    • The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA. The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 2003; 23: 2264-2276.
    • (2003) Mol Cell Biol , vol.23 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 32
    • 84867305210 scopus 로고    scopus 로고
    • Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation
    • McDade SS, Henry AE, Pivato GP, Kozarewa I, Mitsopoulos C, Fenwick K et al. Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation. Nucleic Acids Res 2012; 40: 7190-7206.
    • (2012) Nucleic Acids Res , vol.40 , pp. 7190-7206
    • McDade, S.S.1    Henry, A.E.2    Pivato, G.P.3    Kozarewa, I.4    Mitsopoulos, C.5    Fenwick, K.6
  • 33
    • 79952237500 scopus 로고    scopus 로고
    • The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer
    • Buckley NE, Conlon SJ, Jirstrom K, Kay EW, Crawford NT, O'Grady A et al. The DeltaNp63 proteins are key allies of BRCA1 in the prevention of basal-like breast cancer. Cancer Res 2011; 71: 1933-1944.
    • (2011) Cancer Res , vol.71 , pp. 1933-1944
    • Buckley, N.E.1    Conlon, S.J.2    Jirstrom, K.3    Kay, E.W.4    Crawford, N.T.5    O'Grady, A.6
  • 34
    • 84875781320 scopus 로고    scopus 로고
    • Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: Identification of a novel p63/Her2/neu expressing subgroup
    • Shekhar MP, Kato I, Nangia-Makker P, Tait L. Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup. Oncotarget 2013; 4: 231-241.
    • (2013) Oncotarget , vol.4 , pp. 231-241
    • Shekhar, M.P.1    Kato, I.2    Nangia-Makker, P.3    Tait, L.4
  • 35
    • 79960015997 scopus 로고    scopus 로고
    • Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
    • Lehmann BD, Bauer JA, Chen X, Sanders ME, Chakravarthy AB, Shyr Y et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011; 121: 2750-2767.
    • (2011) J Clin Invest , vol.121 , pp. 2750-2767
    • Lehmann, B.D.1    Bauer, J.A.2    Chen, X.3    Sanders, M.E.4    Chakravarthy, A.B.5    Shyr, Y.6
  • 36
    • 0345304246 scopus 로고    scopus 로고
    • Positive and negative regulation of deltaN-p63 promoter activity by p53 and deltaN-p63-alpha contributes to differential regulation of p53 target genes
    • Harmes DC, Bresnick E, Lubin EA, Watson JK, Heim KE, Curtin JC et al. Positive and negative regulation of deltaN-p63 promoter activity by p53 and deltaN-p63-alpha contributes to differential regulation of p53 target genes. Oncogene 2003; 22: 7607-7616.
    • (2003) Oncogene , vol.22 , pp. 7607-7616
    • Harmes, D.C.1    Bresnick, E.2    Lubin, E.A.3    Watson, J.K.4    Heim, K.E.5    Curtin, J.C.6
  • 38
    • 84877056160 scopus 로고    scopus 로고
    • p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model
    • Olsen JR, Oyan AM, Rostad K, Hellem MR, Liu J, Li L et al. p63 attenuates epithelial to mesenchymal potential in an experimental prostate cell model. PLoS One 2013; 8: e62547.
    • (2013) PLoS One , vol.8
    • Olsen, J.R.1    Oyan, A.M.2    Rostad, K.3    Hellem, M.R.4    Liu, J.5    Li, L.6
  • 39
    • 84866546174 scopus 로고    scopus 로고
    • Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer
    • Tucci P, Agostini M, Grespi F, Markert EK, Terrinoni A, Vousden KH et al. Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci USA 2012; 109: 15312-15317.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 15312-15317
    • Tucci, P.1    Agostini, M.2    Grespi, F.3    Markert, E.K.4    Terrinoni, A.5    Vousden, K.H.6
  • 40
    • 84872573955 scopus 로고    scopus 로고
    • DeltaNp63alpha-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells
    • Balboni AL, Hutchinson JA, DeCastro AJ, Cherukuri P, Liby K, Sporn MB et al. DeltaNp63alpha-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer Res 2013; 73: 1020-1030.
    • (2013) Cancer Res , vol.73 , pp. 1020-1030
    • Balboni, A.L.1    Hutchinson, J.A.2    DeCastro, A.J.3    Cherukuri, P.4    Liby, K.5    Sporn, M.B.6
  • 41
    • 84925298125 scopus 로고    scopus 로고
    • DeltaNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling
    • Chakrabarti R, Wei Y, Hwang J, Hang X, Andres Blanco M, Choudhury A et al. DeltaNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signalling. Nat Cell Biol 2014; 16: 1004-1015 1-13.
    • (2014) Nat Cell Biol , vol.16
    • Chakrabarti, R.1    Wei, Y.2    Hwang, J.3    Hang, X.4    Andres Blanco, M.5    Choudhury, A.6
  • 43
    • 84890283025 scopus 로고    scopus 로고
    • Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes
    • Lehmann BD, Pietenpol JA. Identification and use of biomarkers in treatment strategies for triple-negative breast cancer subtypes. J Pathol 2014; 232: 142-150.
    • (2014) J Pathol , vol.232 , pp. 142-150
    • Lehmann, B.D.1    Pietenpol, J.A.2
  • 44
    • 27744489092 scopus 로고    scopus 로고
    • p63 correlates with both BRCA1 and cytokeratin 5 in invasive breast carcinomas: Further evidence for the pathogenesis of the basal phenotype of breast cancer
    • Ribeiro-Silva A, Ramalho LN, Garcia SB, Brandao DF, Chahud F, Zucoloto S. p63 correlates with both BRCA1 and cytokeratin 5 in invasive breast carcinomas: further evidence for the pathogenesis of the basal phenotype of breast cancer. Histopathology 2005; 47: 458-466.
    • (2005) Histopathology , vol.47 , pp. 458-466
    • Ribeiro-Silva, A.1    Ramalho, L.N.2    Garcia, S.B.3    Brandao, D.F.4    Chahud, F.5    Zucoloto, S.6
  • 45
    • 27644567107 scopus 로고    scopus 로고
    • p63, cytokeratin 5, and P-cadherin: Three molecular markers to distinguish basal phenotype in breast carcinomas
    • Matos I, Dufloth R, Alvarenga M, Zeferino LC, Schmitt F. p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas. Virchows Arch 2005; 447: 688-694.
    • (2005) Virchows Arch , vol.447 , pp. 688-694
    • Matos, I.1    Dufloth, R.2    Alvarenga, M.3    Zeferino, L.C.4    Schmitt, F.5
  • 47
    • 84872550777 scopus 로고    scopus 로고
    • Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer
    • Prat A, Cheang MC, Martin M, Parker JS, Carrasco E, Caballero R et al. Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer. J Clin Oncol 2013; 31: 203-209.
    • (2013) J Clin Oncol , vol.31 , pp. 203-209
    • Prat, A.1    Cheang, M.C.2    Martin, M.3    Parker, J.S.4    Carrasco, E.5    Caballero, R.6
  • 48
    • 33847147313 scopus 로고    scopus 로고
    • American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
    • Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol 2007; 25: 118-145.
    • (2007) J Clin Oncol , vol.25 , pp. 118-145
    • Wolff, A.C.1    Hammond, M.E.2    Schwartz, J.N.3    Hagerty, K.L.4    Allred, D.C.5    Cote, R.J.6
  • 49
    • 2342476480 scopus 로고    scopus 로고
    • A molecular signature of the Nottingham prognostic index in breast cancer
    • Yu K, Lee CH, Tan PH, Hong GS, Wee SB, Wong CY et al. A molecular signature of the Nottingham prognostic index in breast cancer. Cancer Res 2004; 64: 2962-2968.
    • (2004) Cancer Res , vol.64 , pp. 2962-2968
    • Yu, K.1    Lee, C.H.2    Tan, P.H.3    Hong, G.S.4    Wee, S.B.5    Wong, C.Y.6
  • 51
    • 38949105905 scopus 로고    scopus 로고
    • Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution
    • Allred DC, Wu Y, Mao S, Nagtegaal ID, Lee S, Perou CM et al. Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution. Clin Cancer Res 2008; 14: 370-378.
    • (2008) Clin Cancer Res , vol.14 , pp. 370-378
    • Allred, D.C.1    Wu, Y.2    Mao, S.3    Nagtegaal, I.D.4    Lee, S.5    Perou, C.M.6
  • 53
    • 33847198956 scopus 로고    scopus 로고
    • HER2 status of bone marrow micrometastasis and their corresponding primary tumours in a pilot study of 27 cases: A possible tool for anti-HER2 therapy management?
    • Vincent-Salomon A, Pierga JY, Couturier J, d'Enghien CD, Nos C, Sigal-Zafrani B et al. HER2 status of bone marrow micrometastasis and their corresponding primary tumours in a pilot study of 27 cases: a possible tool for anti-HER2 therapy management? Br J Cancer 2007; 96: 654-659.
    • (2007) Br J Cancer , vol.96 , pp. 654-659
    • Vincent-Salomon, A.1    Pierga, J.Y.2    Couturier, J.3    D'Enghien, C.D.4    Nos, C.5    Sigal-Zafrani, B.6
  • 54
    • 45349084318 scopus 로고    scopus 로고
    • The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
    • Sakurai-Yageta M, Recchi C, Le Dez G, Sibarita JB, Daviet L, Camonis J et al. The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA. J Cell Biol 2008; 181: 985-998.
    • (2008) J Cell Biol , vol.181 , pp. 985-998
    • Sakurai-Yageta, M.1    Recchi, C.2    Le Dez, G.3    Sibarita, J.B.4    Daviet, L.5    Camonis, J.6
  • 56
    • 13944259795 scopus 로고    scopus 로고
    • Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia
    • Teuliere J, Faraldo MM, Deugnier MA, Shtutman M, Ben-Ze'ev A, Thiery JP et al. Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Development 2005; 132: 267-277.
    • (2005) Development , vol.132 , pp. 267-277
    • Teuliere, J.1    Faraldo, M.M.2    Deugnier, M.A.3    Shtutman, M.4    Ben-Ze'ev, A.5    Thiery, J.P.6
  • 57
    • 0033973613 scopus 로고    scopus 로고
    • Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene
    • Lohi J, Lehti K, Valtanen H, Parks WC, Keski-Oja J. Structural analysis and promoter characterization of the human membrane-type matrix metalloproteinase-1 (MT1-MMP) gene. Gene 2000; 242: 75-86.
    • (2000) Gene , vol.242 , pp. 75-86
    • Lohi, J.1    Lehti, K.2    Valtanen, H.3    Parks, W.C.4    Keski-Oja, J.5
  • 58
    • 77957371805 scopus 로고    scopus 로고
    • Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus
    • Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE, Alonso ME et al. Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus. PLoS Genet 2010; 6: e1001065.
    • (2010) PLoS Genet , vol.6
    • Kouwenhoven, E.N.1    Van Heeringen, S.J.2    Tena, J.J.3    Oti, M.4    Dutilh, B.E.5    Alonso, M.E.6
  • 59
    • 84863786613 scopus 로고    scopus 로고
    • Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63
    • Martynova E, Pozzi S, Basile V, Dolfini D, Zambelli F, Imbriano C et al. Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63. Oncotarget 2012; 3: 132-143.
    • (2012) Oncotarget , vol.3 , pp. 132-143
    • Martynova, E.1    Pozzi, S.2    Basile, V.3    Dolfini, D.4    Zambelli, F.5    Imbriano, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.