메뉴 건너뛰기




Volumn 54, Issue 2, 2017, Pages 977-982

A Missense Variant in TREML2 Reduces Risk of Alzheimer’s Disease in a Han Chinese Population

Author keywords

Alzheimer s disease; Han Chinese; TREML2; Variant

Indexed keywords

APOLIPOPROTEIN E4; IMMUNOGLOBULIN RECEPTOR; TREML2 PROTEIN, HUMAN;

EID: 84955263698     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9706-8     Document Type: Article
Times cited : (14)

References (26)
  • 1
    • 84865576332 scopus 로고    scopus 로고
    • Novel disease-modifying therapies for Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC38Xht1GhurbN
    • Jiang T, Yu JT, Tan L (2012) Novel disease-modifying therapies for Alzheimer’s disease. J Alzheime Dis: JAD 31(3):475–492. doi:10.3233/JAD-2012-120640
    • (2012) J Alzheime Dis: JAD , vol.31 , Issue.3 , pp. 475-492
    • Jiang, T.1    Yu, J.T.2    Tan, L.3
  • 2
    • 84888062913 scopus 로고    scopus 로고
    • Epidemiology and etiology of Alzheimer’s disease: from genetic to non-genetic factors
    • COI: 1:CAS:528:DC%2BC3sXhsFKktLzE
    • Jiang T, Yu JT, Tian Y, Tan L (2013) Epidemiology and etiology of Alzheimer’s disease: from genetic to non-genetic factors. Curr Alzheim Res 10(8):852–867
    • (2013) Curr Alzheim Res , vol.10 , Issue.8 , pp. 852-867
    • Jiang, T.1    Yu, J.T.2    Tian, Y.3    Tan, L.4
  • 3
    • 84903627137 scopus 로고    scopus 로고
    • Alzheimer’s disease genetics: from the bench to the clinic
    • COI: 1:CAS:528:DC%2BC2cXhtFWgt7nN, PID: 24991952
    • Karch CM, Cruchaga C, Goate AM (2014) Alzheimer’s disease genetics: from the bench to the clinic. Neuron 83(1):11–26. doi:10.1016/j.neuron.2014.05.041
    • (2014) Neuron , vol.83 , Issue.1 , pp. 11-26
    • Karch, C.M.1    Cruchaga, C.2    Goate, A.M.3
  • 4
    • 84904678185 scopus 로고    scopus 로고
    • Apolipoprotein e in Alzheimer’s disease: an update
    • COI: 1:CAS:528:DC%2BC2cXhsVKgt7fP, PID: 24821312
    • Yu JT, Tan L, Hardy J (2014) Apolipoprotein e in Alzheimer’s disease: an update. Annu Rev Neurosci 37:79–100. doi:10.1146/annurev-neuro-071013-014300
    • (2014) Annu Rev Neurosci , vol.37 , pp. 79-100
    • Yu, J.T.1    Tan, L.2    Hardy, J.3
  • 5
    • 84867608942 scopus 로고    scopus 로고
    • The genetics of Alzheimer disease
    • Tanzi RE (2012) The genetics of Alzheimer disease. Cold Spring Harbor Perspect Med 2(10):a006296. doi:10.1101/cshperspect.a006296
    • (2012) Cold Spring Harbor Perspect Med , vol.2 , Issue.10 , pp. a006296
    • Tanzi, R.E.1
  • 6
    • 84888317489 scopus 로고    scopus 로고
    • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3sXhs1yiu7vJ, PID: 24162737
    • Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC et al (2013) Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nat Genet 45(12):1452–1458. doi:10.1038/ng.2802
    • (2013) Nat Genet , vol.45 , Issue.12 , pp. 1452-1458
    • Lambert, J.C.1    Ibrahim-Verbaas, C.A.2    Harold, D.3    Naj, A.C.4    Sims, R.5    Bellenguez, C.6    DeStafano, A.L.7    Bis, J.C.8
  • 9
    • 84875261136 scopus 로고
    • (2013) TREM2 is associated with the risk of Alzheimer’s disease in Spanish population
    • Benitez BA, Cooper B, Pastor P, Jin SC, Lorenzo E, Cervantes S, Cruchaga C (2013) TREM2 is associated with the risk of Alzheimer’s disease in Spanish population. Neurobiology of aging 34 (6):1711 e1715-1717. doi:10.1016/j.neurobiolaging.2012.12.018
    • (1711) Neurobiology of aging , vol.34 , Issue.6 , pp. e1715-e1717
    • Benitez, B.A.1    Cooper, B.2    Pastor, P.3    Jin, S.C.4    Lorenzo, E.5    Cervantes, S.6    Cruchaga, C.7
  • 12
    • 84884165090 scopus 로고    scopus 로고
    • Assessment of TREM2 rs75932628 association with Alzheimer’s disease in a population-based sample: the Cache County Study
    • Gonzalez Murcia JD, Schmutz C, Munger C, Perkes A, Gustin A, Peterson M, Ebbert MT, Norton MC et al (2013) Assessment of TREM2 rs75932628 association with Alzheimer’s disease in a population-based sample: the Cache County Study. Neurobiol Aging 34(12):2889 e2811–2883. doi:10.1016/j.neurobiolaging.2013.06.004
    • (2013) Neurobiol Aging , vol.34 , Issue.12 , pp. 2889 e2811-2883
    • Gonzalez Murcia, J.D.1    Schmutz, C.2    Munger, C.3    Perkes, A.4    Gustin, A.5    Peterson, M.6    Ebbert, M.T.7    Norton, M.C.8
  • 13
    • 84921984443 scopus 로고    scopus 로고
    • The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk
    • COI: 1:CAS:528:DC%2BC2cXhsleiu7fJ, PID: 25186855
    • Hooli BV, Parrado AR, Mullin K, Yip WK, Liu T, Roehr JT, Qiao D, Jessen F et al (2014) The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk. Neurology 83(15):1353–1358. doi:10.1212/WNL.0000000000000855
    • (2014) Neurology , vol.83 , Issue.15 , pp. 1353-1358
    • Hooli, B.V.1    Parrado, A.R.2    Mullin, K.3    Yip, W.K.4    Liu, T.5    Roehr, J.T.6    Qiao, D.7    Jessen, F.8
  • 15
    • 85058205511 scopus 로고    scopus 로고
    • Triggering receptor expressed on myeloid cells 2 variant is rare in late-onset Alzheimer’s disease in Han Chinese individuals
    • Yu JT, Jiang T, Wang YL, Wang HF, Zhang W, Hu N, Tan L, Sun L et al (2014) Triggering receptor expressed on myeloid cells 2 variant is rare in late-onset Alzheimer’s disease in Han Chinese individuals. Neurobiol Aging 35(4):937 e931–933. doi:10.1016/j.neurobiolaging.2013.10.075
    • (2014) Neurobiol Aging , vol.35 , Issue.4 , pp. 937 e931-933
    • Yu, J.T.1    Jiang, T.2    Wang, Y.L.3    Wang, H.F.4    Zhang, W.5    Hu, N.6    Tan, L.7    Sun, L.8
  • 17
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s disease
    • COI: 1:STN:280:DyaL2c3ks1altQ%3D%3D, PID: 6610841
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer’s disease. Neurology 34(7):939–944
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 18
    • 84860513790 scopus 로고    scopus 로고
    • Common variants in toll-like receptor 4 confer susceptibility to Alzheimer’s disease in a Han Chinese population
    • COI: 1:CAS:528:DC%2BC38XmslWrtbw%3D
    • Yu JT, Miao D, Cui WZ, Ou JR, Tian Y, Wu ZC, Zhang W, Tan L (2012) Common variants in toll-like receptor 4 confer susceptibility to Alzheimer’s disease in a Han Chinese population. Curr Alzheim Res 9(4):458–466
    • (2012) Curr Alzheim Res , vol.9 , Issue.4 , pp. 458-466
    • Yu, J.T.1    Miao, D.2    Cui, W.Z.3    Ou, J.R.4    Tian, Y.5    Wu, Z.C.6    Zhang, W.7    Tan, L.8
  • 19
    • 85058205408 scopus 로고    scopus 로고
    • Genetic variation in PICALM and Alzheimer’s disease risk in Han Chinese
    • Jiang T, Yu JT, Tan MS, Wang HF, Wang YL, Zhu XC, Zhang W, Tan L (2014) Genetic variation in PICALM and Alzheimer’s disease risk in Han Chinese. Neurobiol Aging 35(4):934 e931–933. doi:10.1016/j.neurobiolaging.2013.09.014
    • (2014) Neurobiol Aging , vol.35 , Issue.4 , pp. 934 e931-933
    • Jiang, T.1    Yu, J.T.2    Tan, M.S.3    Wang, H.F.4    Wang, Y.L.5    Zhu, X.C.6    Zhang, W.7    Tan, L.8
  • 20
    • 84876786043 scopus 로고    scopus 로고
    • GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3sXlsVKhu78%3D, PID: 23562540
    • Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT et al (2013) GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer’s disease. Neuron 78(2):256–268. doi:10.1016/j.neuron.2013.02.026
    • (2013) Neuron , vol.78 , Issue.2 , pp. 256-268
    • Cruchaga, C.1    Kauwe, J.S.2    Harari, O.3    Jin, S.C.4    Cai, Y.5    Karch, C.M.6    Benitez, B.A.7    Jeng, A.T.8
  • 21
    • 64049095240 scopus 로고    scopus 로고
    • TREM and TREM-like receptors in inflammation and disease
    • COI: 1:CAS:528:DC%2BD1MXksVCntrg%3D, PID: 19230638
    • Ford JW, McVicar DW (2009) TREM and TREM-like receptors in inflammation and disease. Curr Opin Immunol 21(1):38–46. doi:10.1016/j.coi.2009.01.009
    • (2009) Curr Opin Immunol , vol.21 , Issue.1 , pp. 38-46
    • Ford, J.W.1    McVicar, D.W.2
  • 22
    • 79952256613 scopus 로고    scopus 로고
    • Genome-wide association of familial late-onset Alzheimer’s disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE
    • COI: 1:CAS:528:DC%2BC3MXisl2ntrc%3D, PID: 21379329
    • Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD et al (2011) Genome-wide association of familial late-onset Alzheimer’s disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. PLoS Genet 7(2), e1001308. doi:10.1371/journal.pgen.1001308
    • (2011) PLoS Genet , vol.7 , Issue.2
    • Wijsman, E.M.1    Pankratz, N.D.2    Choi, Y.3    Rothstein, J.H.4    Faber, K.M.5    Cheng, R.6    Lee, J.H.7    Bird, T.D.8
  • 23
    • 84939950813 scopus 로고    scopus 로고
    • Bridging integrator 1 (BIN1) genotype effects on working memory, hippocampal volume, and functional connectivity in young healthy individuals
    • COI: 1:CAS:528:DC%2BC2MXivFaju70%3D
    • Zhang X, Yu JT, Li J, Wang C, Tan L, Liu B, Jiang T (2015) Bridging integrator 1 (BIN1) genotype effects on working memory, hippocampal volume, and functional connectivity in young healthy individuals. Neuropsychopharmacol Off Publ Am College Neuropsychopharmacol 40(7):1794–1803. doi:10.1038/npp.2015.30
    • (2015) Neuropsychopharmacol Off Publ Am College Neuropsychopharmacol , vol.40 , Issue.7 , pp. 1794-1803
    • Zhang, X.1    Yu, J.T.2    Li, J.3    Wang, C.4    Tan, L.5    Liu, B.6    Jiang, T.7
  • 24
    • 84862777328 scopus 로고    scopus 로고
    • The role of clusterin in Alzheimer’s disease: pathways, pathogenesis, and therapy
    • COI: 1:CAS:528:DC%2BC38XksVertrY%3D, PID: 22274961
    • Yu JT, Tan L (2012) The role of clusterin in Alzheimer’s disease: pathways, pathogenesis, and therapy. Mol Neurobiol 45(2):314–326. doi:10.1007/s12035-012-8237-1
    • (2012) Mol Neurobiol , vol.45 , Issue.2 , pp. 314-326
    • Yu, J.T.1    Tan, L.2
  • 25
    • 84896698958 scopus 로고    scopus 로고
    • TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in Han Chinese
    • COI: 1:CAS:528:DC%2BC3sXhslWmurnN, PID: 24166182
    • Lu RC, Wang H, Tan MS, Yu JT, Tan L (2014) TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in Han Chinese. J Neural Transm 121(3):283–287. doi:10.1007/s00702-013-1106-x
    • (2014) J Neural Transm , vol.121 , Issue.3 , pp. 283-287
    • Lu, R.C.1    Wang, H.2    Tan, M.S.3    Yu, J.T.4    Tan, L.5
  • 26
    • 84862831893 scopus 로고    scopus 로고
    • SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in a Northern Han Chinese population
    • COI: 1:CAS:528:DC%2BC38Xkt1egs7Y%3D, PID: 22353753
    • Wang HF, Yu JT, Zhang W, Wang W, Liu QY, Ma XY, Ding HM, Tan L (2012) SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in a Northern Han Chinese population. Brain Res 1448:111–116. doi:10.1016/j.brainres.2012.01.067
    • (2012) Brain Res , vol.1448 , pp. 111-116
    • Wang, H.F.1    Yu, J.T.2    Zhang, W.3    Wang, W.4    Liu, Q.Y.5    Ma, X.Y.6    Ding, H.M.7    Tan, L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.