The rare TREM2 R47H variant exerts only a modest effect on alzheimer disease risk

Neurology

Volumn 83, Issue 15, 2014, Pages 1353-1358

  Hooli, Basavaraj V ^a   Parrado, Antonio R ^a   Mullin, Kristina ^a   Yip, Wai Ki ^b   Liu, Tian ^c   Roehr, Johannes T ^c   Qiao, Dandi ^b   Jessen, Frank ^d,e   Peters, Oliver ^f   Becker, Tim ^d,e   Ramirez, Alfredo ^d   Lange, Christoph ^b   Bertram, Lars ^c   Tanzi, Rudolph E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d UNIVERSITY OF BONN   (Germany)

^e GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE RECEPTOR; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM2 PROTEIN, HUMAN;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CAUCASIAN; CONTROL; CONTROLLED STUDY; EXON; FOLLOW UP; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS;

ALZHEIMER DISEASE; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MEMBRANE GLYCOPROTEINS; MUTATION, MISSENSE; RECEPTORS, IMMUNOLOGIC;

EID: 84921984443     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000000855     Document Type: Article

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