Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells - possible implications for the ICOS/ICOS-ligand axis in disease course and resolution

Clinical and Experimental Immunology

Volumn 183, Issue 2, 2016, Pages 294-306

  Sakthivel, P ^a,b   Grunewald, J ^c   Eklund, A ^c   Bruder, D ^a,b   Wahlstrom J ^a,b,c  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

ICOS; ICOS L; L fgren's syndrome; Regulatory T cells; Sarcoidosis

Indexed keywords

BIOLOGICAL MARKER; CD4 ANTIGEN; CYTOKINE; INDUCIBLE COSTIMULATOR; INDUCIBLE T CELL COSTIMULATOR LIGAND; UNCLASSIFIED DRUG; ICOS PROTEIN, HUMAN; INDUCIBLE T CELL COSTIMULATOR; LIGAND;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE COURSE; EFFECTOR CELL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOREGULATION; LOFGREN SYNDROME; LUNG LAVAGE; LUNG SARCOIDOSIS; MALE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; TH1 CELL; AGED; BLOOD; BRONCHOALVEOLAR LAVAGE FLUID; CYTOLOGY; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; MIDDLE AGED; NORMAL HUMAN; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGED; BIOMARKERS; BRONCHOALVEOLAR LAVAGE FLUID; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION; HEALTHY VOLUNTEERS; HUMANS; INDUCIBLE T-CELL CO-STIMULATOR PROTEIN; LIGANDS; LUNG; MALE; MIDDLE AGED; MONOCYTES; SARCOIDOSIS, PULMONARY; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY;

EID: 84955215901     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12715     Document Type: Article

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