Reversal of global CD4+ subset dysfunction is associated with spontaneous clinical resolution of pulmonary sarcoidosis

Journal of Immunology

Volumn 190, Issue 11, 2013, Pages 5446-5453

  Oswald Richter, Kyra A ^a   Richmond, Bradley W ^a   Braun, Nicole A ^a   Isom, Joan ^a   Abraham, Susamma ^b   Taylor, Thyneice R ^a   Drake, John M ^c   Culver, Daniel A ^b   Wilkes, David S ^d   Drake, Wonder P ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; PROTEIN KINASE C THETA; PROTEIN TYROSINE KINASE; SRC KINASE LCK; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIGENICITY; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; FEMALE; GENE; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IL2 GENE; IMMUNE DYSREGULATION; LUNG LAVAGE; LUNG SARCOIDOSIS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MAJOR CLINICAL STUDY; MALE; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T CELL DEPLETION; TH1 CELL;

ADULT; AGED; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CLONAL ANERGY; FEMALE; HUMANS; INTERLEUKIN-2; MALE; MIDDLE AGED; RECEPTORS, ANTIGEN, T-CELL; REMISSION, SPONTANEOUS; SARCOIDOSIS, PULMONARY; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; YOUNG ADULT;

EID: 84878093771     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202891     Document Type: Article

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