Lung T-helper cells expressing T-cell receptor AV2S3 associate with clinical features of pulmonary sarcoidosis

American Journal of Respiratory and Critical Care Medicine

Volumn 161, Issue 3 I, 2000, Pages 814-818

  Grunewald, Johan ^a   Berlin, Mary ^b   Olerup, Olle ^b   Eklund, Anders ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HLA DR ANTIGEN; T LYMPHOCYTE RECEPTOR;

ADULT; AGE; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HELPER CELL; HUMAN; INFLAMMATION; LUNG LAVAGE; LUNG SARCOIDOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION;

EID: 0034109136     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.161.3.9906001     Document Type: Article

References (21)

1. Newman, L., C. Rose, and L. Maier. 1997. Sarcoidosis. N. Engl. J. Med. 336:1224-1234.
2. Hunninghake, G., and R. Crystal. 1981. Pulmonary sarcoidosis: a disorder mediated by excess helper T-lymphocyte activity at sites of disease activity. N. Engl. J. Med. 305:429-434.
3. Robinson, R., T. McLemore, and R. Crystal. 1985. Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis. J. Clin. Invest. 75:1488-1505.
4. Müller-Quernheim, J., C. Saltini, P. Sondermeyer, and R. Crystal. 1986. Compartmentalized activation of the interleukin-2 gene by lung T lymphocytes in active pulmonary sarcoidosis. J. Immunol. 137:3475-3483.
5. Davis, M., and P. Bjorkman. 1988. T cell antigen receptor genes and T cell recognition. Nature 334:395-402.
6. Winoto, A., J. Urban, N. Lan, J. Goverman, L. Hood, and D. Hansburg. 1986. Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c. Nature 324:679-682.
7. Acha-Orbea, H., D. Mitchell, L. Timmermann, D. Wraith, G. Tausch, M. Waldor, S. Zamvil, H. McDevitt, and L. Steinmann. 1988. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell 54: 263-273.
8. Argaet, V., C. Schmidt, S. Burrowa, S. Silins, M. Kurilla, D. Doolan, A. Suhrbier, D. Moss, E. Kieff, T. Sculley, and I. Misko. 1994. Dominant selection of an invariant T cell antigen receptor in response to persistent infection with Epstein-Barr virus. J. Exp. Med. 180:2335-2340.
9. Lehner, P., E. Wang, P. Moss, S. Williams, K. Platt, S. Friedman, J. Bell, and L. Borysiewicz. 1995. Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of Influenza A is dominated by T cells bearing the V beta 17 gene segment. J. Exp. Med. 181:79-91.
10. + T lymphocytes in bronchoalveolar lavage fluid from sarcoidosis patients correlates with HLA-DR3. Eur. J. Immunol. 22:129-135.
11. + T cells in bronchoalveolar lavage fluid and peripheral blood of sarcoidosis patients. Proc. Natl Acad. Sci. U.S.A. 91:4965-4969.
12. + sarcoidosis patients. Mol. Med. 1:287-296.
13. + cell ratios in bronchoalveolar lavage fluid: of value for diagnosing sarcoidosis? Eur. Respir. J. 10:2699-2700.
14. Berlin, M., A. Fogdell-Hahn, O. Olerup, A. Eklund, and J. Grunewald. 1997. HLA-DR predicts the prognosis in Scandinavian patients with pulmonary sarcoidosis. Am. J. Respir. Crit. Care Med. 156:1601-1605.
15. + human peripheral blood T lymphocytes. Eur. J. Immunol. 21:819-822.
16. Wahlström, J., M. Berlin, R. Lundgren, O. Olerup, H. Wigzell, A. Eklund, and J. Grunewald. 1997. Lung and blood T-cell receptor repertoire in extrinsic allergic alveolitis. Eur. Respir. J. 10:772-779.
17. Oksenberg, J., M. Panzara, A. Begovich, D. Mitchell, H. Erlich, R. Murray, R. Shimonkevitz, M. Sherritt, J. Rothbard, C. Bernard, and L. Steinman. 1993. Selection for T-cell receptor V beta-D beta-J beta gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature 362:68-70.
18. Grunewald, J., and H. Wigzell. 1996. T cell expansions in healthy individuals. Immunologist 4:99-103.
19. Posnett, D., R. Sinha, S. Kabak, and C. Russo. 1994. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy." J. Exp. Med. 179:609-618.
20. Burastero, W., B. Borgonovo, D. Gaffi, E. Frittoli, A. Wack, G. A. Rossi, and E. Crimi. 1996. The repertoire of T lymphocytes recovered by bronchoalveolar lavage from healthy nonsmokers. Eur. Respir. J. 9:319-327.
21. Yurovsky, V., E. Bleecker, and B. White. 1996. Restricted T-cell antigen receptor repertoire in bronchoalveolar T cells from normal humans. Hum. Immunol. 50:22-37.