Unique molecular signatures influencing the biological function and fate of post-natal stem cells isolated from different sources

Journal of Tissue Engineering and Regenerative Medicine

Volumn 9, Issue 12, 2015, Pages E252-E266

  Abu Kasim, Noor Hayaty ^a   Govindasamy, Vijayendran ^a,b   Gnanasegaran, Nareshwaran ^a   Musa, Sabri ^a   Pradeep, Padmaja Jayaprasad ^a   Srijaya, Thekkeparambil Chandrabose ^a   Aziz, Zeti Adura Che Ab ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b Hygieia Innovation Sdn Bhd   (Malaysia)

Author keywords

Adipose; Bone marrow; Dental pulp; Gene expression; Mesenchymal stem cells; Wharton's jelly

Indexed keywords

BONE; CELL MEMBRANES; DISEASE CONTROL; FLOWCHARTING; GENE EXPRESSION; STEM CELLS;

ADIPOSE; ADIPOSE TISSUE; BONE MARROW; CELL-BE; CELL/B.E; DENTAL PULP; GENES EXPRESSION; MESENCHYMAL STEM CELL; STEM-CELL; WHARTON JELLY;

CELL CULTURE;

5' NUCLEOTIDASE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; CD34 ANTIGEN; CD45 ANTIGEN; HLA DR ANTIGEN; NESTIN; OCTAMER TRANSCRIPTION FACTOR 4; THY 1 ANTIGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTOME;

ADIPOSE TISSUE MESENCHYMAL STEM CELL; ADULT; ARTICLE; BETA III TUB GENE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL ISOLATION; CELL MIGRATION; CELL MOTION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURFACE; CHONDROGENESIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOGENETICS; DENTAL PULP STEM CELL; DPPA5 GENE; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; IN VITRO STUDY; KARYOTYPING; MALE; MESENCHYMAL STEM CELL; MOLECULAR DYNAMICS; MOLECULAR STABILITY; NANOG GENE; NESTIN GENE; NEWBORN; NF GENE; OCT4 GENE; POSTNATAL STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REX1 GENE; SOX2 GENE; STELLAR GENE; STEM CELL; TISSUE SPECIFICITY; TRANSCRIPTOMICS; UPREGULATION; WHARTON JELLY MESENCHYMAL STEM CELL; ADIPOSE TISSUE; ANTIBODY SPECIFICITY; BONE MARROW CELL; CLINICAL TRIAL; CYTOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; TOOTH PULP; WHARTON JELLY;

ADIPOSE TISSUE; ADULT; BONE MARROW CELLS; DENTAL PULP; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MALE; MESENCHYMAL STROMAL CELLS; ORGAN SPECIFICITY; TRANSCRIPTOME; WHARTON JELLY;

EID: 84955212960     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1663     Document Type: Article

References (81)

1. Agha-Hosseini F, Jahani MA, Jahani M, et al. 2010; In vitro isolation of stem cells derived from human dental pulp. Clin Transpl 24(2): E23-E28.
2. Al Battah F, De Kock J, Vanhaecke T, et al. 2011; Current status of human adipose-derived stem cells: differentiation into hepatocyte-like cells. Sci World J 11: 1568-1581.
3. Al-Nbaheen M, Vishnubalaji R, Ali D, et al. 2012; Human stromal (mesenchymal) stem cells from bone marrow, adipose tissue and skin exhibit differences in molecular phenotype and differentiation potential. Stem Cell Rev. DOI: 10.1007/s12015-012-9365-8.
4. Akela A, Nandi SK, Banerjee D, et al. 2012; Evaluation of autologous bone marrow in wound healing in animal model: a possible application of autologous stem cells. Int Wound J 9(5): 505-516. DOI: 10.1111/j.1742-481X.2011.00909.x.
5. Antoniou KM, Papadaki HA, Soufla G, et al. 2010; Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in idiopathic pulmonary fibrosis (IPF). Resp Med 104: 1535-1542.
6. Augello A, Kurth TB, De Bari C. 2010; Mesenchymal stem cells: a perspective from in vitro cultures to in vivo migration and niches. Eur Cells Mater 20: 121-133.
7. Avilion A, Nicolis S, Pevny L, et al. 2003; Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17(1): 126-140.
8. Bakopoulou A, Leyhausen G, Volk J, et al. 2011; Comparative analysis of in vitro osteo/odontogenic differentiation potential of human dental pulp stem cells (DPSCs) and stem cells from the apical papilla (SCAP). Arch Oral Biol 56(7): 709-721.
9. Balic A, Anguila HL, Caimano MJ, et al. 2010; Characterization of stem and progenitor cells in the dental pulp of erupted and unerupted murine molars. Bone 46(6): 1639-1651.
10. Bey E, Prat M, Duhamel P, et al. 2010; Emerging therapy for improving wound repair of severe radiation burns using local bone marrow-derived stem cell administrations. Wound Repair Regen 18(1): 50-58.
11. Bittencourt RADC, Pereira HR, Felisbino SL, et al. 2006; Isolation of bone marrow mesenchymal stem cells. Acta Ortop Bras 14(1): 22-24.
12. Breitbach M, Bostani T, Roell W, et al. 2007; Potential risks of bone marrow cell transplantation into infarcted hearts. Blood 110(4):1362-1369.
13. Chambers I, Colby D, Robertson M, et al. 2003. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 113(5): 643-655.
14. Charbord P, Livne E, Gross G, et al. 2011. Human bone marrow mesenchymal stem cells: a systematic reappraisal via the genostem experience. Stem Cells Rev 7: 32-42.
15. Chen LL, Carmichael GG. 2010; Long noncoding RNAs in mammalian cells: what, where, and why? Wiley Interdiscip Rev RNA 1(1): 2-21.
16. Chen MY, Lie PC, Li ZL, et al. 2009a; Endothelial differentiation of Wharton's jelly-derived mesenchymal stem cells in comparison with bone marrow-derived mesenchymal stem cells. Exp Hematol 37(5): 629-640.
17. Chen MY, Lie PC, Li ZL, et al. 2009b; Endothelial differentiation of Wharton's jelly-derived mesenchymal stem cells in comparison with bone marrow-derived mesenchymal stem cells. Exp Hematol 37(5): 629-640.
18. + cells from Wharton's jelly show in vitro and in vivo myogenic differentiation potential. Int J Mol Med 18(6): 1089-1096.
19. de Mattos Carvalho A, Alves ALG, Golim MA, et al. 2009; Isolation and immunophenotypic characterization of mesenchymal stem cells derived from equine species adipose tissue. Vet Immunol Immunopathol 132(2-4): 303-306.
20. Dharmasaroja P. 2009; Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke. J Clin Neurosci 16(1): 12-20.
21. Dominici M, Le Blanc K, Mueller I, et al. 2006; Minimal criteria for defining multipotent mesenchymal stromal cells: the International Society for Cellular Therapy position statement. Cytotherapy 8: 315-317.
22. Duan HF, Wu CT, Wu DL, et al. 2003; Treatment of myocardial ischemia with bone marrow-derived mesenchymal stem cells overexpressing hepatocyte growth factor. Mol Ther 8(3): 467-474.
23. Fong CY, Subramanian A, Biswas A, et al. 2010; Derivation efficiency, cell proliferation, freeze-thaw survival, stem-cell properties and differentiation of human Wharton's jelly stem cells. Reprod Biomed Online 21(3): 391-401.
24. Friedenstein AJ, Piatetzky-Shapiro II, Petrakova KV. 1966; Osteogenesis in transplants of bone marrow cells. J Embryol Exp Morphol 16: 381-390.
25. Gabr MM, Zakaria MM, Refaie AF, et al. 2012. Insulin-producing cells from adult human bone marrow mesenchymal stem cells control streptozotocin-induced diabetes in nude mice. Cell Transpl [Epub ahead of print].
26. Govindasamy V, Ronald VS, Totey S, et al. 2010a; Micromanipulation of culture niche permits long-term expansion of dental pulp stem cells - an economic and commercial angle. In Vitro Cell Dev Biol Anim 46(9):764-773.
27. Govindasamy V, Abdullah AN, Ronald VS, et al. 2010b; Inherent differential propensity of dental pulp stem cells derived from human deciduous and permanent teeth. J Endod 36(9): 1504-1515.
28. Govindasamy V, Ronald VS, Abdullah AN, et al. 2011a; Differentiation of dental pulp stem cells into islet-like aggregates. J Dent Res 90(5): 646-652.
29. Govindasamy V, Ronald VS, Abdullah AN, et al. 2011b; Human platelet lysate permits scale-up of dental pulp stromal cells for clinical applications. Cytotherapy 13(10): 1221-1233.
30. Gronthos S, Arthur A, Bartold PM, et al. 2011; A method to isolate and culture expand human dental pulp stem cells. Methods Mol Biol 698(2): 107-121.
31. Hanson SE, Kim J, Johnson BHQ, et al. 2010; Characterization of mesenchymal stem cells from human vocal fold fibroblast. Laryngoscope 120(3): 546-551.
32. Hill D, Berardini TZ, Howe DG, et al. 2010; Representing ontogeny through ontology: a developmental biologist's guide to the gene ontology. Mol Reprod Dev 77(4): 314-329.
33. Huang da W, Sherman BT, Lempicki RA. 2009; Systematic and integrative analysis of large gene lists using DAVID bioinformatiocs resources. Nat Protoc 4(1): 44-57.
34. Huang P, Lin LM, Wu XY, et al. 2010; Differentiation of human umbilical cord Wharton's jelly-derived mesenchymal stem cells into germ-like cells in vitro. J Cell Biochem 109(4): 747-754.
35. Inanc B, Elcin YM. 2011; Stem cells in tooth tissue regeneration - challenges and limitations. Stem Cell Rev Rep 7(3): 683-692.
36. Ishinge I, Nagamura-Inoue T, Honda MJ, et al. 2009; Comparison of mesenchymal stem cells derived from arterial, venous and Wharton's jelly explants of human umbilical cord. Int J Hematol 90: 261-269.
37. Jansen BJH, Gilissen C, Roelofs H, et al. 2010; Functional differences between mesenchymal stem cells populations are reflected by their transcriptome. Stem Cells Dev 19(4): 481-490.
38. Kadar K, Kiraly M, Porcsalmy B, et al. 2009; Differentiation potential of stem cells from human dental origin - promise for tissue engineering. J Physiol Pharmacol 60(7): 167-175.
39. Kuo YR, Wang CT, Cheng JT, et al. 2011; Bone marrow-derived mesenchymal stem cells enhanced diabetic wound healing through recruitment of tissue regeneration in a rat model of streptozotocin-induced diabetes. Plast Reconstr Surg 128(4): 872-880.
40. Lin SZ, Chang YJ, Liu JW, et al. 2010; Transplantation of human Wharton's jelly-derived stem cells alleviates chemically induced liver fibrosis in rats. Cell Transpl 19(11): 1451-1463.
41. Lindner U, Kramer J, Rohwedel J, et al. 2010; Mesenchymal stem or stromal cells: toward a better understanding of their biology? Transfus Med Hemother 37(2): 75-83.
42. Mallanna SK, Rizzino A. 2010; Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells. Dev Biol 344: 16-25.
43. Mazo M, Gavira JJ, Pelacho B, et al. 2011; Adipose-derived stem cells for myocardial infarction. J Cardiovasc Transl Res 4(2):145-153.
44. + acute leukemia harbor and express the MLL-AF4 fusion gene. J Exp Med 206(13): 3131-3141.
45. Mimeault M, Hauke R, Batra SK. 2007; Stem cells: a revolution in therapeutics - recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin Pharmacol Ther 82(3): 252-264.
46. Miura M, Gronthos S, Zhao M, et al. 2003; SHED: Stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 100(10): 5807-5812.
47. Mohyeddin-Bonab M, Mohamad-Hassani MR, Alimoghaddam K, et al. 2007; Autologous in vitro expanded mesenchymal stem cell therapy for human old myocardial infarction. Arch Iran Med 10(4): 467-473.
48. Mueller SM, Glowacki J. 2001; Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges. J Cell Biochem 82(4): 583-590.
49. Muraglia A, Cancedda R, Quarto R. 2000; Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. J Cell Sci 113: 1161-1166.
50. Nagoshi N, Shibata S, Kubota Y, et al. 2008; Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad. Stem Cell 2(4): 392-403.
51. Nakashima M, Mizunuma K, Murakami T, et al. 2002; Induction of dental pulp stem cell differentiation into odontoblasts by electroporation-mediated gene delivery of growth/differentiation factor 11 (Gdf11). Gene Ther 9(12): 814-818.
52. Nam S, Won JE, Kim CH et al. 2011; Odontogenic differentiation of human dental pulp stem cells stimulated by the calcium phosphate porous granules. J Tissue Eng. DOI: 10.4061/2011/812547.
53. Nekanti U, Dastidar S, Venugopal P, et al. 2010a; Increased proliferation and analysis of differential gene expression in human Wharton's jelly-derived mesenchymal stromal cells under hypoxia. Int J Biol Sci 6(5): 499-512.
54. Nekanti U, Rao VB, Bahirvani AG, et al. 2010b; Long-term expansion and pluripotent marker array analysis of Wharton's jelly-derived mesenchymal stem cells. Stem Cells Dev 19(1): 117-130.
55. Nekanti U, Mohanty L, Venugopal P, et al. 2010c; Optimization and scale-up of Wharton's jelly-derived mesenchymal stem cells for clinical applications. Stem Cell Res 5: 244-254.
56. Neupane M, Chang CC, Kiupel M, et al. 2008; Isolation and characterization of canine adipose-derived mesenchymal stem cells. Tissue Eng Part A 14(6): 1007-1015.
57. Nichols J, Zevnik B, Anastassiadis K, et al. 1998; Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95(3): 379-391.
58. Qian Q, Qian H, Zhang X, et al. 2012; 5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase. Stem Cells Dev 21(1): 67-75.
59. Pal R, Hanwate M, Jan M, et al. 2009; Phenotypic and functional comparison of optimum culture conditions for upscaling of bone marrow-derived mesenchymal stem cells. J Tissue Eng Regen Med 3(3): 163-174.
60. Pal R, Venkataramana NK, Bansal A, et al. 2010; Ex vivo-expanded autologous bone marrow-derived mesenchymal stromal cells in human spinal cord injury/paraplegia: a pilot clinical study. Cytotherapy 11(7): 897-911.
61. Peng J, Wang Y, Zhang L, et al. 2011; Human umbilical cord Wharton's jelly-derived mesenchymal stem cells differentiate into a Schwann-cell phenotype and promote neurite outgrowth in vitro. Brain Res Bull 84(3): 235-243.
62. Rasulov MF, Vasilchenkov AV, Onishchenko NA, et al. 2005; First experience of the use of bone marrow mesenchymal stem cells for the treatment of a patient with deep skin burns. Bull Exp Biol Med 139(1): 141-144.
63. Rizzino A. 2009; Sox2 and Oct-3/4: A versatile pair of master regulators that orchestrate the self-renewal and pluripotency of embryonic stem cells by functioning as molecular rheostats. Wiley Interdiscip Rev Syst Biol Med 1(2): 228-236.
64. Rodríguez-Lozano FJ, Bueno C, Insausti CL, et al. 2011; Mesenchymal stem cells derived from dental tissues. Int Endod J 44(9): 800-806.
65. Rojphisan S, Manochantr S, U-pratya Y, et al. 2009; Characterization of mesenchymal stem cells from umbilical cord and Wharton's jelly in comparison to bone marrow derived mesenchymal stem cells. Thammasat Med J 9(3): 259-26•.
66. Sakai K, Yamamoto A, Matsubara K, et al. 2012; Human dental pulp-derived stem cells promote locomotor recovery after complete transection of the rat spinal cord by multiple neuro-regenerative mechanisms. J Clin Invest 122(1): 80-90.
67. Sathishkumar S, Mohanashankar P, Boopalan PRJVC. 2011; Cell surface protein expression of stem cells from human adipose tissue at early passage with reference to mesenchymal stem cell phenotype. Int J Med Med Sci 3(5): 129-134.
68. Satomura K, Krebsbach P, Bianco P, et al. 2000. Osteogenic imprinting upstream of marrow stromal cell differentiation. J Cell Biochem 78: 391-403.
69. Secco M, Moreira YB, Zucconi E, et al. 2009; Gene expression profile of mesenchymal stem cells from paired umbilical cord units: cord is different from blood. Stem Cell Rev 5(4): 387-401.
70. Shih DT, Chen JC, Chen WY, et al. 2011; Expansion of adipose tissue mesenchymal stromal progenitors in serum-free medium supplemented with virally inactivated allogeneic human platelet lysate. Transfusion 51(4): 770-778.
71. Sotiropoulou PA, Perez SA, Salagianni M, et al. 2006; Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells 24: 462-471.
72. Stenderup K, Justesen J, Clausen C, et al. 2003; Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 33: 919-926.
73. Subrammaniyan R, Amalorpavanathan J, Shankar R, et al. 2011. Application of autologous bone marrow mononuclear cells in six patients with advanced chronic critical limb ischemia as a result of diabetes: our experience. Cytotherapy 13(8): 993-999.
74. Tirino V, Paino F, d'Aquino R, et al. 2011; Methods for the identification, characterization and banking of human DPSCs: current strategies and perspectives. Stem Cell Rev Rep 7(3): 608-615.
75. Venugopal P, Balasubramanian S, Majumdar AS, et al. 2011; Isolation, characterization, and gene expression analysis of Wharton's jelly-derived mesenchymal stem cells under xeno-free culture conditions. Stem Cells CloningAdv Applic 4: 39-50.
76. Wang HS, Hung SC, Peng ST, et al. 2004; Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord. Stem Cells 22: 1330-1337.
77. Weiss ML, Anderson C, Medicetty S, et al. 2008; Immune properties of human umbilical cord Wharton's jelly-derived cells. Stem Cells 26(11): 2865-2874.
78. Wen Z, Zheng S, Zhou C, et al. 2011; Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarction. J Cell Mol Med 15(5): 1032-1043.
79. Wu LF, Wang NN, Liu YS, et al. 2009; Differentiation of Wharton's jelly primitive stromal cells into insulin-producing cells in comparison with bone marrow mesenchymal stem cells. Tissue Eng Part A 15(10): 2865-2873.
80. Yamada Y, Ito K, Nakamura S, et al. 2010; Promising cell-based therapy for bone regeneration using stem cells from deciduous teeth, dental pulp, and bone marrow. Cell Transpl 20(7): 1003-1013.
81. Zheng Y, Liu Y, Zhang CM, et al. 2009; Stem cells from deciduous tooth repair mandibular defect in swine. J Dent Res 88(3): 249-254.