메뉴 건너뛰기




Volumn 15, Issue 5, 2011, Pages 1032-1043

Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarction

Author keywords

Bone marrow; Mesenchymal stem cells; Myocardial infarction; Repair mechanisms

Indexed keywords

CYTOKINE;

EID: 79957582277     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01255.x     Document Type: Review
Times cited : (131)

References (100)
  • 1
    • 33644878249 scopus 로고    scopus 로고
    • Cardiovascular disease in the developing world and its cost-effective management
    • Gaziano TA. Cardiovascular disease in the developing world and its cost-effective management. Circulation. 2005; 112: 3547-53.
    • (2005) Circulation. , vol.112 , pp. 3547-3553
    • Gaziano, T.A.1
  • 2
    • 61949196872 scopus 로고    scopus 로고
    • Stem cells in myocardial infarction: from bench to bedside
    • Mollmann H, Nef H, Elsasser A, et al Stem cells in myocardial infarction: from bench to bedside. Heart. 2009; 95: 508-14.
    • (2009) Heart. , vol.95 , pp. 508-514
    • Mollmann, H.1    Nef, H.2    Elsasser, A.3
  • 3
    • 33748059545 scopus 로고    scopus 로고
    • Cardiac stem cell therapy. Need for optimization of efficacy and safety monitoring
    • Oettgen P, Boyle AJ, Schulman SP, et al Cardiac stem cell therapy. Need for optimization of efficacy and safety monitoring. Circulation. 2006; 114: 353-8.
    • (2006) Circulation. , vol.114 , pp. 353-358
    • Oettgen, P.1    Boyle, A.J.2    Schulman, S.P.3
  • 4
    • 0033106384 scopus 로고    scopus 로고
    • Cardiomyocytes can be generated from marrow stromal cellsin vitro
    • Makino S, Fukuda K, Miyoshi S, et al Cardiomyocytes can be generated from marrow stromal cellsin vitro. J Clin Invest. 1999; 103: 697-705.
    • (1999) J Clin Invest. , vol.103 , pp. 697-705
    • Makino, S.1    Fukuda, K.2    Miyoshi, S.3
  • 5
    • 0033678140 scopus 로고    scopus 로고
    • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
    • Liechty KW, MacKenzie TC, Shaaban AF, et al Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med. 2000; 6: 1282-6.
    • (2000) Nat Med. , vol.6 , pp. 1282-1286
    • Liechty, K.W.1    MacKenzie, T.C.2    Shaaban, A.F.3
  • 6
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC, et al Multilineage potential of adult human mesenchymal stem cells. Science. 1999; 284: 143-7.
    • (1999) Science. , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 7
    • 59149087667 scopus 로고    scopus 로고
    • Mesenchymal stem cells improve outcomes of cardiopulmonary resuscitation in myocardial infarcted rats
    • Wang T, Tang W, Sun S, et al Mesenchymal stem cells improve outcomes of cardiopulmonary resuscitation in myocardial infarcted rats. J Mol Cell Cardiol. 2009; 46: 378-84.
    • (2009) J Mol Cell Cardiol. , vol.46 , pp. 378-384
    • Wang, T.1    Tang, W.2    Sun, S.3
  • 8
    • 62849109614 scopus 로고    scopus 로고
    • Improved outcomes of cardiopulmonary resuscitation in rats with myocardial infarction treated with allogenic bone marrow mesenchymal stem cells
    • Wang T, Tang W, Sun S, et al Improved outcomes of cardiopulmonary resuscitation in rats with myocardial infarction treated with allogenic bone marrow mesenchymal stem cells. Crit Care Med. 2009; 37: 833-9.
    • (2009) Crit Care Med. , vol.37 , pp. 833-839
    • Wang, T.1    Tang, W.2    Sun, S.3
  • 9
    • 70350484991 scopus 로고    scopus 로고
    • Cardiac cell repair therapy: a clinical perspective
    • Gersh BJ, Simari RD, Behfar A, et al Cardiac cell repair therapy: a clinical perspective. Mayo Clin Proc. 2009; 84: 876-92.
    • (2009) Mayo Clin Proc. , vol.84 , pp. 876-892
    • Gersh, B.J.1    Simari, R.D.2    Behfar, A.3
  • 10
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S, et al Bone marrow cells regenerate infarcted myocardium. Nature. 2001; 410: 701-5.
    • (2001) Nature. , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 11
    • 33645410509 scopus 로고    scopus 로고
    • Cell-to-cell contact induces mesenchymal stem cell to differentiate into cardiomyocyte and smooth muscle cell
    • Wang T, Xu Z, Jiang W, et al Cell-to-cell contact induces mesenchymal stem cell to differentiate into cardiomyocyte and smooth muscle cell. Int J Cardiol. 2006; 109: 74-81.
    • (2006) Int J Cardiol. , vol.109 , pp. 74-81
    • Wang, T.1    Xu, Z.2    Jiang, W.3
  • 12
    • 23744499651 scopus 로고    scopus 로고
    • Effects of bone marrow derived mesenchymal stem cells transplantation in acutely infarcting myocardium
    • Piao H, Youn TJ, Kwon JS, et al Effects of bone marrow derived mesenchymal stem cells transplantation in acutely infarcting myocardium. Eur J Heart Fail. 2005; 7: 730-8.
    • (2005) Eur J Heart Fail. , vol.7 , pp. 730-738
    • Piao, H.1    Youn, T.J.2    Kwon, J.S.3
  • 13
    • 33749013538 scopus 로고    scopus 로고
    • Homing and differentiation of mesenchymal stem cells delivered intravenously to ischemic myocardiumin vivo: a time-series study
    • Jiang W, Ma A, Wang T, et al Homing and differentiation of mesenchymal stem cells delivered intravenously to ischemic myocardiumin vivo: a time-series study. Pflugers Arch. 2006; 453: 43-52.
    • (2006) Pflugers Arch. , vol.453 , pp. 43-52
    • Jiang, W.1    Ma, A.2    Wang, T.3
  • 14
    • 69549138471 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathyviatrilineage differentiating capacity
    • Quevedo HC, Hatzistergos KE, Oskouei BN, et al Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathyviatrilineage differentiating capacity. Proc Natl Acad Sci USA. 2009; 106: 14022-7.
    • (2009) Proc Natl Acad Sci USA. , vol.106 , pp. 14022-14027
    • Quevedo, H.C.1    Hatzistergos, K.E.2    Oskouei, B.N.3
  • 15
    • 30944448824 scopus 로고    scopus 로고
    • Mesenchymal, but not hematopoietic, stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction in mice
    • Fukuda K, Fujita J. Mesenchymal, but not hematopoietic, stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction in mice. Kidney Int. 2005; 68: 1940-3.
    • (2005) Kidney Int. , vol.68 , pp. 1940-1943
    • Fukuda, K.1    Fujita, J.2
  • 16
    • 33744908550 scopus 로고    scopus 로고
    • Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance
    • Berry MF, Engler AJ, Woo YJ, et al Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance. Am J Physiol Heart Circ Physiol. 2006; 290: H2196-203.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Berry, M.F.1    Engler, A.J.2    Woo, Y.J.3
  • 17
    • 56249148884 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells express cardiac-specific markers, retain the stromal phenotype, and do not become functional cardiomyocytesin vitro
    • Rose RA, Jiang H, Wang X, et al Bone marrow-derived mesenchymal stromal cells express cardiac-specific markers, retain the stromal phenotype, and do not become functional cardiomyocytesin vitro. Stem Cells. 2008; 26: 2884-92.
    • (2008) Stem Cells. , vol.26 , pp. 2884-2892
    • Rose, R.A.1    Jiang, H.2    Wang, X.3
  • 18
    • 19944432052 scopus 로고    scopus 로고
    • Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model
    • Silva GV, Litovsky S, Assad JA, et al Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation. 2005; 111: 150-6.
    • (2005) Circulation. , vol.111 , pp. 150-156
    • Silva, G.V.1    Litovsky, S.2    Assad, J.A.3
  • 19
    • 33645530042 scopus 로고    scopus 로고
    • Human mesenchymal stem cells do not differentiate into cardiomyocytes in a cardiac ischemic xenomodel
    • Grinnemo KH, Mansson-Broberg A, Leblanc K, et al Human mesenchymal stem cells do not differentiate into cardiomyocytes in a cardiac ischemic xenomodel. Ann Med. 2006; 38: 144-53.
    • (2006) Ann Med. , vol.38 , pp. 144-153
    • Grinnemo, K.H.1    Mansson-Broberg, A.2    Leblanc, K.3
  • 20
    • 42349110746 scopus 로고    scopus 로고
    • Early homing of adult mesenchymal stem cells in normal and infarcted isolated beating hearts
    • Penna C, Raimondo S, Ronchi G, et al Early homing of adult mesenchymal stem cells in normal and infarcted isolated beating hearts. J Cell Mol Med. 2008; 12: 507-21.
    • (2008) J Cell Mol Med. , vol.12 , pp. 507-521
    • Penna, C.1    Raimondo, S.2    Ronchi, G.3
  • 21
    • 9344265225 scopus 로고    scopus 로고
    • Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis
    • Nagaya N, Fujii T, Iwase T, et al Intravenous administration of mesenchymal stem cells improves cardiac function in rats with acute myocardial infarction through angiogenesis and myogenesis. Am J Physiol Heart Circ Physiol. 2004; 287: H2670-6.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Nagaya, N.1    Fujii, T.2    Iwase, T.3
  • 22
    • 33846401855 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells differentiate into functional cardiac phenotypes by cardiac microenvironment
    • Li X, Yu X, Lin Q, et al Bone marrow mesenchymal stem cells differentiate into functional cardiac phenotypes by cardiac microenvironment. J Mol Cell Cardiol. 2007; 42: 295-303.
    • (2007) J Mol Cell Cardiol. , vol.42 , pp. 295-303
    • Li, X.1    Yu, X.2    Lin, Q.3
  • 23
    • 55049129824 scopus 로고    scopus 로고
    • Impact of myocardial infarct proteins and oscillating pressure on the differentiation of mesenchymal stem cells: effect of acute myocardial infarction on stem cell differentiation
    • Chang SA, Lee EJ, Kang HJ, et al Impact of myocardial infarct proteins and oscillating pressure on the differentiation of mesenchymal stem cells: effect of acute myocardial infarction on stem cell differentiation. Stem Cells. 2008; 26: 1901-12.
    • (2008) Stem Cells. , vol.26 , pp. 1901-1912
    • Chang, S.A.1    Lee, E.J.2    Kang, H.J.3
  • 24
    • 33845438599 scopus 로고    scopus 로고
    • Effects of myocardial transplantation of marrow mesenchymal stem cells transfected with vascular endothelial growth factor for the improvement of heart function and angiogenesis after myocardial infarction
    • Yang J, Zhou W, Zheng W, et al Effects of myocardial transplantation of marrow mesenchymal stem cells transfected with vascular endothelial growth factor for the improvement of heart function and angiogenesis after myocardial infarction. Cardiology. 2007; 107: 17-29.
    • (2007) Cardiology. , vol.107 , pp. 17-29
    • Yang, J.1    Zhou, W.2    Zheng, W.3
  • 25
    • 49249101551 scopus 로고    scopus 로고
    • Forced myocardin expression enhances the therapeutic effect of human mesenchymal stem cells after transplantation in ischemic mouse hearts
    • Grauss RW, van Tuyn J, Steendijk P, et al Forced myocardin expression enhances the therapeutic effect of human mesenchymal stem cells after transplantation in ischemic mouse hearts. Stem Cells. 2008; 26: 1083-93.
    • (2008) Stem Cells. , vol.26 , pp. 1083-1093
    • Grauss, R.W.1    van Tuyn, J.2    Steendijk, P.3
  • 26
    • 36749001126 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 improves the efficacy of mesenchymal stem cells transplantation in a rat model of myocardial infarction
    • Guo J, Lin G, Bao C, et al Insulin-like growth factor 1 improves the efficacy of mesenchymal stem cells transplantation in a rat model of myocardial infarction. J Biomed Sci. 2008; 15: 89-97.
    • (2008) J Biomed Sci. , vol.15 , pp. 89-97
    • Guo, J.1    Lin, G.2    Bao, C.3
  • 27
    • 41549105367 scopus 로고    scopus 로고
    • Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism
    • Crisostomo PR, Wang Y, Markel TA, et al Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an NF kappa B- but not JNK-dependent mechanism. Am J Physiol Cell Physiol. 2008; 294: C675-82.
    • (2008) Am J Physiol Cell Physiol , vol.294
    • Crisostomo, P.R.1    Wang, Y.2    Markel, T.A.3
  • 28
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects
    • Dai W, Hale SL, Martin BJ, et al Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: short- and long-term effects. Circulation. 2005; 112: 214-23.
    • (2005) Circulation. , vol.112 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3
  • 29
    • 2942523981 scopus 로고    scopus 로고
    • Mesenchymal stem cells can be differentiated into endothelial cellsin vitro
    • Oswald J, Boxberger S, Jorgensen B, et al Mesenchymal stem cells can be differentiated into endothelial cellsin vitro. Stem Cells. 2004; 22: 377-84.
    • (2004) Stem Cells. , vol.22 , pp. 377-384
    • Oswald, J.1    Boxberger, S.2    Jorgensen, B.3
  • 30
    • 77953016267 scopus 로고    scopus 로고
    • SDF-1/CXCR4-mediated migration of transplanted bone marrow stromal cells toward areas of heart myocardial infarction through activation of PI3K/Akt
    • Yu J, Li M, Qu Z, et al SDF-1/CXCR4-mediated migration of transplanted bone marrow stromal cells toward areas of heart myocardial infarction through activation of PI3K/Akt. J Cardiovasc Pharmacol. 2010; 55: 496-505.
    • (2010) J Cardiovasc Pharmacol. , vol.55 , pp. 496-505
    • Yu, J.1    Li, M.2    Qu, Z.3
  • 31
    • 69849084725 scopus 로고    scopus 로고
    • Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats
    • Tang J, Wang J, Yang J, et al Mesenchymal stem cells over-expressing SDF-1 promote angiogenesis and improve heart function in experimental myocardial infarction in rats. Eur J Cardiothorac Surg. 2009; 36: 644-50.
    • (2009) Eur J Cardiothorac Surg. , vol.36 , pp. 644-650
    • Tang, J.1    Wang, J.2    Yang, J.3
  • 32
    • 37349036435 scopus 로고    scopus 로고
    • Locally overexpressing hepatocyte growth factor prevents post-ischemic heart failure by inhibition of apoptosisviacalcineurin-mediated pathway and angiogenesis
    • Guo Y, He J, Wu J, et al Locally overexpressing hepatocyte growth factor prevents post-ischemic heart failure by inhibition of apoptosisviacalcineurin-mediated pathway and angiogenesis. Arch Med Res. 2008; 39: 179-88.
    • (2008) Arch Med Res. , vol.39 , pp. 179-188
    • Guo, Y.1    He, J.2    Wu, J.3
  • 33
    • 20144382339 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction
    • Matsumoto R, Omura T, Yoshiyama M, et al Vascular endothelial growth factor-expressing mesenchymal stem cell transplantation for the treatment of acute myocardial infarction. Arterioscler Thromb Vasc Biol. 2005; 25: 1168-73.
    • (2005) Arterioscler Thromb Vasc Biol. , vol.25 , pp. 1168-1173
    • Matsumoto, R.1    Omura, T.2    Yoshiyama, M.3
  • 34
    • 70749095115 scopus 로고    scopus 로고
    • Enhanced mesenchymal cell engraftment by IGF-1 improves left ventricular function in rats undergoing myocardial infarction
    • Enoki C, Otani H, Sato D, et al Enhanced mesenchymal cell engraftment by IGF-1 improves left ventricular function in rats undergoing myocardial infarction. Int J Cardiol. 2010; 138: 9-18.
    • (2010) Int J Cardiol. , vol.138 , pp. 9-18
    • Enoki, C.1    Otani, H.2    Sato, D.3
  • 35
    • 77956107611 scopus 로고    scopus 로고
    • The effect of age on the efficacy of human mesenchymal stem cell transplantation after a myocardial infarction
    • Fan M, Chen W, Liu W, et al The effect of age on the efficacy of human mesenchymal stem cell transplantation after a myocardial infarction. Rejuvenation Res. 2010; 13: 429-38.
    • (2010) Rejuvenation Res. , vol.13 , pp. 429-438
    • Fan, M.1    Chen, W.2    Liu, W.3
  • 36
    • 77950671531 scopus 로고    scopus 로고
    • Micropatterned three-dimensional hydrogel system to study human endothelial-mesenchymal stem cell interactions
    • Trkov S, Eng G, Di Liddo R, et al Micropatterned three-dimensional hydrogel system to study human endothelial-mesenchymal stem cell interactions. J Tissue Eng Regen Med. 2010; 4: 205-15.
    • (2010) J Tissue Eng Regen Med. , vol.4 , pp. 205-215
    • Trkov, S.1    Eng, G.2    Di Liddo, R.3
  • 37
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M, Zhang Z, Ni A, et al Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res. 2008; 103: 1204-19.
    • (2008) Circ Res. , vol.103 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3
  • 38
    • 1642373909 scopus 로고    scopus 로고
    • Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promotein vitroandin vivoarteriogenesis through paracrine mechanisms
    • Kinnaird T, Stabile E, Burnett MS, et al Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promotein vitroandin vivoarteriogenesis through paracrine mechanisms. Circ Res. 2004; 94: 678-85.
    • (2004) Circ Res. , vol.94 , pp. 678-685
    • Kinnaird, T.1    Stabile, E.2    Burnett, M.S.3
  • 39
    • 19944426939 scopus 로고    scopus 로고
    • Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion
    • Kajstura J, Rota M, Whang B, et al Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res. 2005; 96: 127-37.
    • (2005) Circ Res. , vol.96 , pp. 127-137
    • Kajstura, J.1    Rota, M.2    Whang, B.3
  • 40
    • 38349112704 scopus 로고    scopus 로고
    • A placebo controlled, dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction
    • Hashemi SM, Ghods S, Kolodgie FD, et al A placebo controlled, dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction. Eur Heart J. 2008; 29: 251-9.
    • (2008) Eur Heart J. , vol.29 , pp. 251-259
    • Hashemi, S.M.1    Ghods, S.2    Kolodgie, F.D.3
  • 41
    • 33751038565 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation
    • Noiseux N, Gnecchi M, Lopez-Ilasaca M, et al Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation. Mol Ther. 2006; 14: 840-50.
    • (2006) Mol Ther. , vol.14 , pp. 840-850
    • Noiseux, N.1    Gnecchi, M.2    Lopez-Ilasaca, M.3
  • 42
    • 33646252939 scopus 로고    scopus 로고
    • Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement
    • Gnecchi M, He H, Noiseux N, et al Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. FASEB J. 2006; 20: 661-9.
    • (2006) FASEB J. , vol.20 , pp. 661-669
    • Gnecchi, M.1    He, H.2    Noiseux, N.3
  • 43
    • 58149169162 scopus 로고    scopus 로고
    • Cardiogenic differentiation and transdifferentiation of progenitor cells
    • Reinecke H, Minami E, Zhu WZ, et al Cardiogenic differentiation and transdifferentiation of progenitor cells. Circ Res. 2008; 103: 1058-71.
    • (2008) Circ Res. , vol.103 , pp. 1058-1071
    • Reinecke, H.1    Minami, E.2    Zhu, W.Z.3
  • 44
    • 33846467107 scopus 로고    scopus 로고
    • Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche
    • Mazhari R, Hare JM. Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche. Nat Clin Pract Cardiovasc Med. 2007; 4: S21-6.
    • (2007) Nat Clin Pract Cardiovasc Med , vol.4
    • Mazhari, R.1    Hare, J.M.2
  • 45
    • 77958012860 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation
    • Hatzistergos KE, Quevedo H, Oskouei BN, et al Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation. Circ Res. 2010: DOI:.
    • (2010) Circ Res
    • Hatzistergos, K.E.1    Quevedo, H.2    Oskouei, B.N.3
  • 46
    • 70449518977 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes cardiac stem cell migrationviathe PI3K/Akt pathway
    • Tang J, Wang J, Kong X, et al Vascular endothelial growth factor promotes cardiac stem cell migrationviathe PI3K/Akt pathway. Exp Cell Res. 2009; 315: 3521-31.
    • (2009) Exp Cell Res. , vol.315 , pp. 3521-3531
    • Tang, J.1    Wang, J.2    Kong, X.3
  • 47
    • 26244460357 scopus 로고    scopus 로고
    • Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival
    • Urbanek K, Rota M, Cascapera S, et al Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival. Circ Res. 2005; 97: 663-73.
    • (2005) Circ Res. , vol.97 , pp. 663-673
    • Urbanek, K.1    Rota, M.2    Cascapera, S.3
  • 48
    • 70349783458 scopus 로고    scopus 로고
    • Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction
    • Padin-Iruegas ME, Misao Y, Davis ME, et al Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction. Circulation. 2009; 120: 876-87.
    • (2009) Circulation. , vol.120 , pp. 876-887
    • Padin-Iruegas, M.E.1    Misao, Y.2    Davis, M.E.3
  • 49
    • 70449705826 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repair
    • Zisa D, Shabbir A, Suzuki G, et al Vascular endothelial growth factor (VEGF) as a key therapeutic trophic factor in bone marrow mesenchymal stem cell-mediated cardiac repair. Biochem Biophys Res Commun. 2009; 390: 834-8.
    • (2009) Biochem Biophys Res Commun. , vol.390 , pp. 834-838
    • Zisa, D.1    Shabbir, A.2    Suzuki, G.3
  • 50
    • 65549171187 scopus 로고    scopus 로고
    • Cell therapy generates a favourable chemokine gradient for stem cell recruitment into the infarcted heart in rabbits
    • Lee BC, Hsu HC, Tseng WY, et al Cell therapy generates a favourable chemokine gradient for stem cell recruitment into the infarcted heart in rabbits. Eur J Heart Fail. 2009; 11: 238-45.
    • (2009) Eur J Heart Fail. , vol.11 , pp. 238-245
    • Lee, B.C.1    Hsu, H.C.2    Tseng, W.Y.3
  • 51
    • 66149093343 scopus 로고    scopus 로고
    • Stem cell homing and angiomyogenesis in transplanted hearts are enhanced by combined intramyocardial SDF-1alpha delivery and endogenous cytokine signaling
    • Zhao T, Zhang D, Millard RW, et al Stem cell homing and angiomyogenesis in transplanted hearts are enhanced by combined intramyocardial SDF-1alpha delivery and endogenous cytokine signaling. Am J Physiol Heart Circ Physiol. 2009; 296: H976-86.
    • (2009) Am J Physiol Heart Circ Physiol , vol.296
    • Zhao, T.1    Zhang, D.2    Millard, R.W.3
  • 52
    • 18844380715 scopus 로고    scopus 로고
    • Regeneration of infarcted myocardium by intramyocardial implantation ofex vivotransforming growth factor-beta-preprogrammed bone marrow stem cells
    • Li TS, Hayashi M, Ito H, et al Regeneration of infarcted myocardium by intramyocardial implantation ofex vivotransforming growth factor-beta-preprogrammed bone marrow stem cells. Circulation. 2005; 111: 2438-45.
    • (2005) Circulation. , vol.111 , pp. 2438-2445
    • Li, T.S.1    Hayashi, M.2    Ito, H.3
  • 53
    • 20544450374 scopus 로고    scopus 로고
    • Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction
    • Tang YL, Zhao Q, Qin X, et al Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction. Ann Thorac Surg. 2005; 80: 229-36.
    • (2005) Ann Thorac Surg. , vol.80 , pp. 229-236
    • Tang, Y.L.1    Zhao, Q.2    Qin, X.3
  • 54
    • 77953706481 scopus 로고    scopus 로고
    • Effects of estrogen on diverse stem cells and relevant intracellular mechanisms
    • Sun H, Wang H, Hu S. Effects of estrogen on diverse stem cells and relevant intracellular mechanisms. Sci China Life Sci. 2010; 53: 542-7.
    • (2010) Sci China Life Sci. , vol.53 , pp. 542-547
    • Sun, H.1    Wang, H.2    Hu, S.3
  • 55
    • 33645734621 scopus 로고    scopus 로고
    • Estradiol enhances recovery after myocardial infarction by augmenting incorporation of bone marrow-derived endothelial progenitor cells into sites of ischemia-induced neovascularizationviaendothelial nitric oxide synthase-mediated activation of matrix metalloproteinase-9
    • Iwakura A, Shastry S, Luedemann C, et al Estradiol enhances recovery after myocardial infarction by augmenting incorporation of bone marrow-derived endothelial progenitor cells into sites of ischemia-induced neovascularizationviaendothelial nitric oxide synthase-mediated activation of matrix metalloproteinase-9. Circulation. 2006; 113: 1605-14.
    • (2006) Circulation. , vol.113 , pp. 1605-1614
    • Iwakura, A.1    Shastry, S.2    Luedemann, C.3
  • 56
    • 52749089852 scopus 로고    scopus 로고
    • Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization
    • Johansson U, Rasmusson I, Niclou SP, et al Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization. Diabetes. 2008; 57: 2393-401.
    • (2008) Diabetes. , vol.57 , pp. 2393-2401
    • Johansson, U.1    Rasmusson, I.2    Niclou, S.P.3
  • 57
    • 49549092228 scopus 로고    scopus 로고
    • VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma
    • Beckermann BM, Kallifatidis G, Groth A, et al VEGF expression by mesenchymal stem cells contributes to angiogenesis in pancreatic carcinoma. Br J Cancer. 2008; 99: 622-31.
    • (2008) Br J Cancer. , vol.99 , pp. 622-631
    • Beckermann, B.M.1    Kallifatidis, G.2    Groth, A.3
  • 58
    • 34147158400 scopus 로고    scopus 로고
    • Mesenchymal stem cells regulate angiogenesis according to their mechanical environment
    • Kasper G, Dankert N, Tuischer J, et al Mesenchymal stem cells regulate angiogenesis according to their mechanical environment. Stem Cells. 2007; 25: 903-10.
    • (2007) Stem Cells. , vol.25 , pp. 903-910
    • Kasper, G.1    Dankert, N.2    Tuischer, J.3
  • 59
    • 33750740096 scopus 로고    scopus 로고
    • Experimental study of bone marrow-derived mesenchymal stem cells combined with hepatocyte growth factor transplantationvianoninfarct-relative artery in acute myocardial infarction
    • Yang ZJ, Ma DC, Wang W, et al Experimental study of bone marrow-derived mesenchymal stem cells combined with hepatocyte growth factor transplantationvianoninfarct-relative artery in acute myocardial infarction. Gene Ther. 2006; 13: 1564-8.
    • (2006) Gene Ther. , vol.13 , pp. 1564-1568
    • Yang, Z.J.1    Ma, D.C.2    Wang, W.3
  • 60
    • 56249148883 scopus 로고    scopus 로고
    • Secreted frizzled-related protein-1 enhances mesenchymal stem cell function in angiogenesis and contributes to neovessel maturation
    • Dufourcq P, Descamps B, Tojais NF, et al Secreted frizzled-related protein-1 enhances mesenchymal stem cell function in angiogenesis and contributes to neovessel maturation. Stem Cells. 2008; 26: 2991-3001.
    • (2008) Stem Cells. , vol.26 , pp. 2991-3001
    • Dufourcq, P.1    Descamps, B.2    Tojais, N.F.3
  • 61
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 2005; 105: 1815-22.
    • (2005) Blood. , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 62
    • 48849096045 scopus 로고    scopus 로고
    • Mesenchymal stem cell-derived IL-10 and recovery from infarction: a third pitch for the chord
    • Bishopric NH. Mesenchymal stem cell-derived IL-10 and recovery from infarction: a third pitch for the chord. Circ Res. 2008; 103: 125-7.
    • (2008) Circ Res. , vol.103 , pp. 125-127
    • Bishopric, N.H.1
  • 63
    • 53249127066 scopus 로고    scopus 로고
    • Immuno-inflammatory regulation effect of mesenchymal stem cell transplantation in a rat model of myocardial infarction
    • Du YY, Zhou SH, Zhou T, et al Immuno-inflammatory regulation effect of mesenchymal stem cell transplantation in a rat model of myocardial infarction. Cytotherapy. 2008; 10: 469-78.
    • (2008) Cytotherapy. , vol.10 , pp. 469-478
    • Du, Y.Y.1    Zhou, S.H.2    Zhou, T.3
  • 64
    • 20144382493 scopus 로고    scopus 로고
    • Increased heme oxygenase-1 expression in infarcted rat hearts following human bone marrow mesenchymal cell transplantation
    • Zhang S, Lu S, Ge J, et al Increased heme oxygenase-1 expression in infarcted rat hearts following human bone marrow mesenchymal cell transplantation. Microvasc Res. 2005; 69: 64-70.
    • (2005) Microvasc Res. , vol.69 , pp. 64-70
    • Zhang, S.1    Lu, S.2    Ge, J.3
  • 65
    • 52949146346 scopus 로고    scopus 로고
    • Effects of combined mesenchymal stem cells and heme oxygenase-1 therapy on cardiac performance
    • Zeng B, Chen H, Zhu C, et al Effects of combined mesenchymal stem cells and heme oxygenase-1 therapy on cardiac performance. Eur J Cardiothorac Surg. 2008; 34: 850-6.
    • (2008) Eur J Cardiothorac Surg. , vol.34 , pp. 850-856
    • Zeng, B.1    Chen, H.2    Zhu, C.3
  • 66
    • 77952365320 scopus 로고    scopus 로고
    • TNF receptor 2, NOT tnf receptor 1, enhances mesenchymal stem cell-mediated cardiac protection following acute ischemia
    • Kelly ML, Wang M, Crisostomo PR, et al TNF receptor 2, NOT tnf receptor 1, enhances mesenchymal stem cell-mediated cardiac protection following acute ischemia. Shock. 2010; 33: 602-7.
    • (2010) Shock. , vol.33 , pp. 602-607
    • Kelly, M.L.1    Wang, M.2    Crisostomo, P.R.3
  • 67
    • 33845608157 scopus 로고    scopus 로고
    • Gender differences in injury induced mesenchymal stem cell apoptosis and VEGF, TNF, IL-6 expression: role of the 55 kDa TNF receptor (TNFR1)
    • Crisostomo PR, Wang M, Herring CM, et al Gender differences in injury induced mesenchymal stem cell apoptosis and VEGF, TNF, IL-6 expression: role of the 55 kDa TNF receptor (TNFR1). J Mol Cell Cardiol. 2007; 42: 142-9.
    • (2007) J Mol Cell Cardiol. , vol.42 , pp. 142-149
    • Crisostomo, P.R.1    Wang, M.2    Herring, C.M.3
  • 68
    • 40949085086 scopus 로고    scopus 로고
    • Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart functionviaenhanced survival of implanted cells and angiogenesis
    • Hu X, Yu SP, Fraser JL, et al Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart functionviaenhanced survival of implanted cells and angiogenesis. J Thorac Cardiovasc Surg. 2008; 135: 799-808.
    • (2008) J Thorac Cardiovasc Surg. , vol.135 , pp. 799-808
    • Hu, X.1    Yu, S.P.2    Fraser, J.L.3
  • 69
    • 34547901409 scopus 로고    scopus 로고
    • Bcl-2 engineered MSCs inhibited apoptosis and improved heart function
    • Li W, Ma N, Ong LL, et al Bcl-2 engineered MSCs inhibited apoptosis and improved heart function. Stem Cells. 2007; 25: 2118-27.
    • (2007) Stem Cells. , vol.25 , pp. 2118-2127
    • Li, W.1    Ma, N.2    Ong, L.L.3
  • 70
    • 33846845067 scopus 로고    scopus 로고
    • Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair
    • Mirotsou M, Zhang Z, Deb A, et al Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair. Proc Natl Acad Sci USA. 2007; 104: 1643-8.
    • (2007) Proc Natl Acad Sci USA. , vol.104 , pp. 1643-1648
    • Mirotsou, M.1    Zhang, Z.2    Deb, A.3
  • 71
    • 73349099336 scopus 로고    scopus 로고
    • Hsp20-engineered mesenchymal stem cells are resistant to oxidative stressviaenhanced activation of Akt and increased secretion of growth factors
    • Wang X, Zhao T, Huang W, et al Hsp20-engineered mesenchymal stem cells are resistant to oxidative stressviaenhanced activation of Akt and increased secretion of growth factors. Stem Cells. 2009; 27: 3021-31.
    • (2009) Stem Cells. , vol.27 , pp. 3021-3031
    • Wang, X.1    Zhao, T.2    Huang, W.3
  • 72
    • 35248875838 scopus 로고    scopus 로고
    • SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction
    • Zhang M, Mal N, Kiedrowski M, et al SDF-1 expression by mesenchymal stem cells results in trophic support of cardiac myocytes after myocardial infarction. FASEB J. 2007; 21: 3197-207.
    • (2007) FASEB J. , vol.21 , pp. 3197-3207
    • Zhang, M.1    Mal, N.2    Kiedrowski, M.3
  • 73
    • 39549105786 scopus 로고    scopus 로고
    • Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction
    • Hahn JY, Cho HJ, Kang HJ, et al Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction. J Am Coll Cardiol. 2008; 51: 933-43.
    • (2008) J Am Coll Cardiol. , vol.51 , pp. 933-943
    • Hahn, J.Y.1    Cho, H.J.2    Kang, H.J.3
  • 74
    • 70349143140 scopus 로고    scopus 로고
    • Lipopolysaccharide preconditioning enhances the efficacy of mesenchymal stem cells transplantation in a rat model of acute myocardial infarction
    • Yao Y, Zhang F, Wang L, et al Lipopolysaccharide preconditioning enhances the efficacy of mesenchymal stem cells transplantation in a rat model of acute myocardial infarction. J Biomed Sci. 2009; 16: 74.
    • (2009) J Biomed Sci , vol.16 , pp. 74
    • Yao, Y.1    Zhang, F.2    Wang, L.3
  • 75
    • 67649628227 scopus 로고    scopus 로고
    • Integrin-linked kinase is required in hypoxic mesenchymal stem cells for strengthening cell adhesion to ischemic myocardium
    • Song SW, Chang W, Song BW, et al Integrin-linked kinase is required in hypoxic mesenchymal stem cells for strengthening cell adhesion to ischemic myocardium. Stem Cells. 2009; 27: 1358-65.
    • (2009) Stem Cells. , vol.27 , pp. 1358-1365
    • Song, S.W.1    Chang, W.2    Song, B.W.3
  • 76
    • 77953919762 scopus 로고    scopus 로고
    • Connexin43 promotes survival of mesenchymal stem cells in ischaemic heart
    • Wang D, Shen W, Zhang F, et al Connexin43 promotes survival of mesenchymal stem cells in ischaemic heart. Cell Biol Int. 2010; 34: 415-23.
    • (2010) Cell Biol Int. , vol.34 , pp. 415-423
    • Wang, D.1    Shen, W.2    Zhang, F.3
  • 77
    • 34548174756 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis
    • Hu X, Dai S, Wu WJ, et al Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation. 2007; 116: 654-63.
    • (2007) Circulation. , vol.116 , pp. 654-663
    • Hu, X.1    Dai, S.2    Wu, W.J.3
  • 78
    • 34547685923 scopus 로고    scopus 로고
    • Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions
    • Ohnishi S, Sumiyoshi H, Kitamura S, et al Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions. FEBS Lett. 2007; 581: 3961-6.
    • (2007) FEBS Lett. , vol.581 , pp. 3961-3966
    • Ohnishi, S.1    Sumiyoshi, H.2    Kitamura, S.3
  • 79
    • 72849145234 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction
    • Mias C, Lairez O, Trouche E, et al Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction. Stem Cells. 2009; 27: 2734-43.
    • (2009) Stem Cells. , vol.27 , pp. 2734-2743
    • Mias, C.1    Lairez, O.2    Trouche, E.3
  • 80
    • 20644471364 scopus 로고    scopus 로고
    • Effects of mesenchymal stem cell transplantation on extracellular matrix after myocardial infarction in rats
    • Xu X, Xu Z, Xu Y, et al Effects of mesenchymal stem cell transplantation on extracellular matrix after myocardial infarction in rats. Coron Artery Dis. 2005; 16: 245-55.
    • (2005) Coron Artery Dis. , vol.16 , pp. 245-255
    • Xu, X.1    Xu, Z.2    Xu, Y.3
  • 81
    • 77955925294 scopus 로고    scopus 로고
    • HO-1 modified mesenchymal stem cells modulate MMPs/TIMPs system and adverse remodeling in infarcted myocardium
    • Shu T, Zeng B, Ren X, et al HO-1 modified mesenchymal stem cells modulate MMPs/TIMPs system and adverse remodeling in infarcted myocardium. Tissue Cell. 2010; 42: 217-22.
    • (2010) Tissue Cell. , vol.42 , pp. 217-222
    • Shu, T.1    Zeng, B.2    Ren, X.3
  • 82
    • 61449140349 scopus 로고    scopus 로고
    • Paracrine action mediate the antifibrotic effect of transplanted mesenchymal stem cells in a rat model of global heart failure
    • Li L, Zhang S, Zhang Y, et al Paracrine action mediate the antifibrotic effect of transplanted mesenchymal stem cells in a rat model of global heart failure. Mol Biol Rep. 2009; 36: 725-31.
    • (2009) Mol Biol Rep. , vol.36 , pp. 725-731
    • Li, L.1    Zhang, S.2    Zhang, Y.3
  • 83
    • 33847073124 scopus 로고    scopus 로고
    • Transplantation of genetically engineered mesenchymal stem cells improves cardiac function in rats with myocardial infarction: benefit of a novel nonviral vector, cationized dextran
    • Jo J, Nagaya N, Miyahara Y, et al Transplantation of genetically engineered mesenchymal stem cells improves cardiac function in rats with myocardial infarction: benefit of a novel nonviral vector, cationized dextran. Tissue Eng. 2007; 13: 313-22.
    • (2007) Tissue Eng. , vol.13 , pp. 313-322
    • Jo, J.1    Nagaya, N.2    Miyahara, Y.3
  • 84
    • 77952543737 scopus 로고    scopus 로고
    • Intra-myocardial delivery of mesenchymal stem cells ameliorates left ventricular and cardiomyocyte contractile dysfunction following myocardial infarction
    • Li Q, Turdi S, Thomas DP, et al Intra-myocardial delivery of mesenchymal stem cells ameliorates left ventricular and cardiomyocyte contractile dysfunction following myocardial infarction. Toxicol Lett. 2010; 195: 119-26.
    • (2010) Toxicol Lett. , vol.195 , pp. 119-126
    • Li, Q.1    Turdi, S.2    Thomas, D.P.3
  • 85
    • 34548394568 scopus 로고    scopus 로고
    • Functional and bioenergetic modulations in the infarct border zone following autologous mesenchymal stem cell transplantation
    • Feygin J, Mansoor A, Eckman P, et al Functional and bioenergetic modulations in the infarct border zone following autologous mesenchymal stem cell transplantation. Am J Physiol Heart Circ Physiol. 2007; 293: H1772-80.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Feygin, J.1    Mansoor, A.2    Eckman, P.3
  • 86
    • 34848834841 scopus 로고    scopus 로고
    • Intravenously injected mesenchymal stem cells home to viable myocardium after coronary occlusion and preserve systolic function without altering infarct size
    • Boomsma RA, Swaminathan PD, Geenen DL. Intravenously injected mesenchymal stem cells home to viable myocardium after coronary occlusion and preserve systolic function without altering infarct size. Int J Cardiol. 2007; 122: 17-28.
    • (2007) Int J Cardiol. , vol.122 , pp. 17-28
    • Boomsma, R.A.1    Swaminathan, P.D.2    Geenen, D.L.3
  • 87
    • 33846433158 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 blocksin vitrocardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum
    • Kumar A, Kumar A, Paladugu B, et al Transforming growth factor-beta1 blocksin vitrocardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum. Crit Care Med. 2007; 35: 358-64.
    • (2007) Crit Care Med. , vol.35 , pp. 358-364
    • Kumar, A.1    Kumar, A.2    Paladugu, B.3
  • 88
    • 77958087304 scopus 로고    scopus 로고
    • Improved function and myocardial repair of infarcted heart by intracoronary injection of mesenchymal stem cell-derived growth factors
    • Nguyen BK, Maltais S, Perrault LP, et al Improved function and myocardial repair of infarcted heart by intracoronary injection of mesenchymal stem cell-derived growth factors. J Cardiovasc Transl Res. 2010; 3: 547-58.
    • (2010) J Cardiovasc Transl Res. , vol.3 , pp. 547-558
    • Nguyen, B.K.1    Maltais, S.2    Perrault, L.P.3
  • 89
    • 33746859703 scopus 로고    scopus 로고
    • Profound bioenergetic abnormalities in peri-infarct myocardial regions
    • Hu Q, Wang X, Lee J, et al Profound bioenergetic abnormalities in peri-infarct myocardial regions. Am J Physiol Heart Circ Physiol. 2006; 291: H648-57.
    • (2006) Am J Physiol Heart Circ Physiol , vol.291
    • Hu, Q.1    Wang, X.2    Lee, J.3
  • 90
    • 65649128494 scopus 로고    scopus 로고
    • Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction
    • Gnecchi M, He H, Melo LG, et al Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. Stem Cells. 2009; 27: 971-9.
    • (2009) Stem Cells. , vol.27 , pp. 971-979
    • Gnecchi, M.1    He, H.2    Melo, L.G.3
  • 91
    • 10744224147 scopus 로고    scopus 로고
    • Mesenchymal stem cell injection induces cardiac nerve sprouting and increased tenascin expression in a Swine model of myocardial infarction
    • Pak HN, Qayyum M, Kim DT, et al Mesenchymal stem cell injection induces cardiac nerve sprouting and increased tenascin expression in a Swine model of myocardial infarction. J Cardiovasc Electrophysiol. 2003; 14: 841-8.
    • (2003) J Cardiovasc Electrophysiol. , vol.14 , pp. 841-848
    • Pak, H.N.1    Qayyum, M.2    Kim, D.T.3
  • 92
    • 77953620382 scopus 로고    scopus 로고
    • Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43-positive gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in canine heart
    • Kim SK, Pak HN, Park JH, et al Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43-positive gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in canine heart. Cardiol Young. 2010; 20: 308-17.
    • (2010) Cardiol Young. , vol.20 , pp. 308-317
    • Kim, S.K.1    Pak, H.N.2    Park, J.H.3
  • 93
    • 79957627022 scopus 로고    scopus 로고
    • cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells
    • Zhang L, Seitz LC, Abramczyk AM, et al cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells. Cell Mol Life Sci. 2010: DOI.
    • (2010) Cell Mol Life Sci
    • Zhang, L.1    Seitz, L.C.2    Abramczyk, A.M.3
  • 94
    • 65349084436 scopus 로고    scopus 로고
    • Stem cell therapy is proarrhythmic
    • Macia E, Boyden PA. Stem cell therapy is proarrhythmic. Circulation. 2009; 119: 1814-23.
    • (2009) Circulation. , vol.119 , pp. 1814-1823
    • Macia, E.1    Boyden, P.A.2
  • 95
    • 65349147149 scopus 로고    scopus 로고
    • Stem cells are not proarrhythmic: letting the genie out of the bottle
    • Ly HQ, Nattel S. Stem cells are not proarrhythmic: letting the genie out of the bottle. Circulation. 2009; 119: 1824-31.
    • (2009) Circulation. , vol.119 , pp. 1824-1831
    • Ly, H.Q.1    Nattel, S.2
  • 96
    • 33646199622 scopus 로고    scopus 로고
    • Proarrhythmic potential of mesenchymal stem cell transplantation revealed in anin vitrococulture model
    • Chang MG, Tung L, Sekar RB, et al Proarrhythmic potential of mesenchymal stem cell transplantation revealed in anin vitrococulture model. Circulation. 2006; 113: 1832-41.
    • (2006) Circulation. , vol.113 , pp. 1832-1841
    • Chang, M.G.1    Tung, L.2    Sekar, R.B.3
  • 97
    • 35548961817 scopus 로고    scopus 로고
    • Autologousin vitroexpanded mesenchymal stem cell therapy for human old myocardial infarction
    • Mohyeddin-Bonab M, Mohamad-Hassani MR, Alimoghaddam K, et al Autologousin vitroexpanded mesenchymal stem cell therapy for human old myocardial infarction. Arch Iran Med. 2007; 10: 467-73.
    • (2007) Arch Iran Med. , vol.10 , pp. 467-473
    • Mohyeddin-Bonab, M.1    Mohamad-Hassani, M.R.2    Alimoghaddam, K.3
  • 98
    • 3042662157 scopus 로고    scopus 로고
    • Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction
    • Chen SL, Fang WW, Ye F, et al Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol. 2004; 94: 92-5.
    • (2004) Am J Cardiol. , vol.94 , pp. 92-95
    • Chen, S.L.1    Fang, W.W.2    Ye, F.3
  • 99
    • 33846343320 scopus 로고    scopus 로고
    • Stem cell therapy enhances electrical viability in myocardial infarction
    • Mills WR, Mal N, Kiedrowski MJ, et al Stem cell therapy enhances electrical viability in myocardial infarction. J Mol Cell Cardiol. 2007; 42: 304-14.
    • (2007) J Mol Cell Cardiol. , vol.42 , pp. 304-314
    • Mills, W.R.1    Mal, N.2    Kiedrowski, M.J.3
  • 100
    • 79955470528 scopus 로고    scopus 로고
    • Mesenchymal stem cell injection ameliorates the inducibility of ventricular arrhythmias after myocardial infarction in rats
    • Wang D, Zhang F, Shen W, et al Mesenchymal stem cell injection ameliorates the inducibility of ventricular arrhythmias after myocardial infarction in rats. Int J Cardiol. 2010: DOI:.
    • (2010) Int J Cardiol
    • Wang, D.1    Zhang, F.2    Shen, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.