Treatment of myocardial ischemia with bone marrow-derived mesenchymal stem cells overexpressing hepatocyte growth factor

Molecular Therapy

Volumn 8, Issue 3, 2003, Pages 467-474

  Duan, Hai Feng ^a   Wu, Chu Tse ^a   Wu, Dan Li ^a   Lu, Ying ^a   Liu, Hong Jun ^a   Ha, Xiao Qin ^a   Zhang, Qun Wei ^a   Wang, Hua ^a   Jia, Xiang Xu ^a   Wang, Li Sheng ^a  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANGIOGENIC FACTOR; CHEMOATTRACTANT; COLLAGEN; COMPLEMENTARY DNA; SCATTER FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL LOSS; CELL REGENERATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HEART FUNCTION; HEART MUSCLE; HEART MUSCLE BLOOD FLOW; HEART MUSCLE CAPILLARY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEMATOPOIETIC STEM CELL; HUMAN; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MARKER GENE; MESENCHYME CELL; NONHUMAN; PROGENY; PROTEIN SECRETION; RAT; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME;

ADENOVIRIDAE; ANIMALIA;

EID: 10744233934     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1525-0016(03)00186-2     Document Type: Article

References (29)

1. Hlatky, M. A. (1996). Analysis of costs associated with CABG and PTCA. Ann. Thoracic Surg. 61: S30-S32.
2. Heuser, R., et al. (2000). A retrospective study of 6,671 patients comparing coronary stenting and balloon angioplasty. J. Invasive Cardiol. 12: 354-362.
3. Malekan, R., et al. (1998). Angiogenesis in transmyocardial laser revascularization: A nonspecific response to injury. Circulation 98(19 Suppl.): II62-II65 discussion II66.
4. Horvath, K. A. (2000). Transmyocardial laser revascularization in the treatment of myocardial ischemia. J. Cardiovasc. Surg. 15: 271-177.
5. Su H., Lu, R., and Kan, Y. W. (2000). Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart. Proc. Natl. Acad. Sci. USA 97: 13801-13806.
6. Losordo, D. W., et al. (1998). Gene therapy for myocardial angiogenesis: Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation 98: 2800-2804.
7. Zhang, C., Yang, J., Feng, J., and Jennings, L. K. (2002). Short-term administration of basic fibroblast growth factor enhances coronary collateral development without exacerbating atherosclerosis and balloon injury-induced vasoproliferation in atherosclerotic rabbits with acute myocardial infarction. J. Lab. Clin. Med. 140: 119-125.
8. Ruel, M., et al. (2002). Long-term effects of surgical angiogenic therapy with fibroblast growth factor 2 protein. J. Thoracic Cardiovasc. Surg. 124: 28-34.
9. Udelson, J. E., et al. (2000). Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe symptomatic chronic coronary artery disease. Circulation 102: 1605-1610.
10. Funatsu, T., et al. (2002). Therapeutic angiogenesis in the ischemic canine heart induced by myocardial injection of naked complementary DNA plasmid encoding hepatocyte growth factor. J. Thoracic Cardiovasc. Surg. 124: 1099-1105.
11. Miyagawa, S., et al. (2002). Myocardial regeneration therapy for heart failure: Hepatocyte growth factor enhances the effect of cellular cardiomyoplasty. Circulation 105: 2556-2561.
12. Jackson, K. A., et al. (2001). Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J. Clin. Invest. 107: 1395-1402.
13. Strauer, B. E., et al. (2002). Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation 106: 1913-1918.
14. Orlic, D., et al. (2001). Bone marrow cells regenerate infarcted myocardium. Nature 410: 701-705.
15. Kadner, A., et al. (2002). A new source for cardiovascular tissue engineering: Human bone marrow stromal cells. Eur. J. Cardiothoracic Surg. 21: 1055-1060.
16. Bruder, S. P., et al. (1998). Mesenchymal stem cells in osteobiology and applied bone regeneration. Clin. Orthop. 355(Suppl.): S247-S256.
17. Ogueta, S., et al. (2002). Prolactin is a component of the human synovial liquid and modulates the growth and chondrogenic differentiation of bone marrow-derived mesenchymal stem cells. Mol. Cell. Endocrinol. 190: 51-63.
18. Murphy, J. M., et al. (2002). Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum. 46: 704-713.
19. Lee, K., et al. (2001). Human mesenchymal stem cells maintain transgene expression during expansion and differentiation. Mol. Ther. 3: 857-866.
20. Shake, J. G., et al. (2002). Mesenchymal stem cell implantation in a swine myocardial infarct model: Engraftment and functional effects. Ann. Thoracic Surg. 73: 1919-1925 discussion 1926.
21. Toma, C., et al. (2002). Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105: 93-98.
22. Rappolee, D. A., Iyer, A., and Patel, Y. (1996). Hepatocyte growth factor and its receptor are expressed in cardiac myocytes during early cardiogenesis. Circ. Res. 78: 1028-1036.
23. Ueda, H., et al. (2001). A potential cardioprotective role of hepatocyte growth factor in myocardial infarction in rats. Cardiovasc. Res. 51: 41-50.
24. Tomita, S., et al. (1999). Autologous transplantation of bone marrow cells improves damaged heart function. Circulation 100(19 Suppl.): II247-II256.
25. Jaiswal, N., Haynesworth, S. E., Caplan, A. I., and Bruder, S. P. (1997). Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro. J. Cell. Biochem. 64: 295-312.
26. Anand, I. S., et al. (1997). Isolated myocyte contractile function is normal in postinfarct remodeled rat heart with systolic dysfunction. Circulation 96: 3974-3984.
27. Robers, C. S., Maclean, D., Maroko, P., and Kloner, R. A. (1984). Early and late remodeling of the left ventricle after acute myocardial infarction. Am. J. Cardiol. 54: 407-410.
28. Kalkman, E. A., van Suylen, R. J., van Dijk, J. P., Saxena, P. R., and Schoemaker, R. G. (1995). Chronic aspirin treatment affects collagen deposition in non-infarcted myocardium during remodeling after coronary artery ligation in the rat. J. Mol. Cell. Cardiol. 27: 2483-2494.
29. An, J., Beauchemin, N., Albanese, J., Abney, T. O., and Sullivan, A. K. (1997). Use of a rat cDNA probe specific for the Y chromosome to detect male-derived cells. J. Androl. 18: 289-293.