Il-10 controls early microglial phenotypes and disease onset in ALS caused by misfolded superoxide dismutase 1

Journal of Neuroscience

Volumn 36, Issue 3, 2016, Pages 1031-1048

  Gravel, Mathieu ^a   Béland, Louis Charles ^a   Soucy, Geneviéve ^a   Abdelhamid, Essam ^a   Rahimian, Reza ^a   Gravel, Claude ^a   Kriz, Jasna ^a  

^a UNIVERSITÉ LAVAL   (Canada)

Author keywords

ALS; Biophotonics; Innate immunity; Microglia; TLR2; Transgenic mice

Indexed keywords

ADENOVIRUS VECTOR; CD11B ANTIGEN; COPPER ZINC SUPEROXIDE DISMUTASE; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; IL10 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIOLUMINESCENCE; CONTROLLED STUDY; CYTOKINE RELEASE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE MUTATION; IMMUNOFLUORESCENCE TEST; INNATE IMMUNITY; MICROGLIA; MICROGLIAL CELL CULTURE; MOUSE; NONHUMAN; OLFACTORY BULB; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FOLDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD; SURVIVAL; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BRAIN; CELL CULTURE; CHEMISTRY; FEMALE; GENETICS; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; CELLS, CULTURED; FEMALE; INTERLEUKIN-10; MALE; MICE; MICE, TRANSGENIC; MICROGLIA; PHENOTYPE; PROTEIN FOLDING; SUPEROXIDE DISMUTASE;

EID: 84955143429     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0854-15.2016     Document Type: Article

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