Chitosan gel-embedded moxifloxacin niosomes: An efficient antimicrobial hybrid system for burn infection

International Journal of Biological Macromolecules

Volumn 85, Issue , 2016, Pages 625-633

  Sohrabi, Shohreh ^a   Haeri, Azadeh ^a   Mahboubi, Arash ^a   Mortazavi, Alireza ^a   Dadashzadeh, Simin ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Chitosan gel; Moxifloxacin; Niosomes

Indexed keywords

CHITOSAN; MOXIFLOXACIN; NIOSOME; ANTIINFECTIVE AGENT; DRUG CARRIER; GEL; QUINOLONE DERIVATIVE;

AGAR DIFFUSION; ANTIMICROBIAL ACTIVITY; ARTICLE; BURN INFECTION; CONTROLLED STUDY; DRUG FORMULATION; IN VITRO STUDY; INFRARED SPECTROSCOPY; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PARTICLE SIZE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SUSTAINED DRUG RELEASE; ZETA POTENTIAL; BURN; CHEMISTRY; COMPLICATION; DRUG DELIVERY SYSTEM; DRUG EFFECTS; DRUG RELEASE; GEL; INFECTION; MEDICINAL CHEMISTRY; MICROBIAL SENSITIVITY TEST; VISCOSITY;

ANTI-INFECTIVE AGENTS; BURNS; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; FLUOROQUINOLONES; GELS; INFECTION; MICROBIAL SENSITIVITY TESTS; PARTICLE SIZE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STAPHYLOCOCCUS AUREUS; VISCOSITY;

EID: 84955105547     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2016.01.013     Document Type: Article

References (58)

1. Church D., Elsayed S., Reid O., Winston B., Lindsay R. Burn wound infections. Clin. Microbiol. Rev. 2006, 19:403-434.
2. Sharma B. Infection in patients with severe burns: causes and prevention thereof. Infect. Dis. Clin. North. Am. 2007, 21:745-759.
3. Sevgi M., Toklu A., Vecchio D., Hamblin M.R. Topical antimicrobials for burn infections-an update. Recent Pat. Anti-infect. Drug Discov. 2013, 8:161.
4. Honari S. Topical therapies and antimicrobials in the management of burn wounds. Crit. Care Nurs. Clin. North Am. 2004, 16:1-11.
5. Kumar G.P., Rajeshwarrao P. Nonionic surfactant vesicular systems for effective drug delivery-an overview. Acta Pharm. Sinica B 2011, 1:208-219.
6. Uchegbu I.F., Vyas S.P. Non-ionic surfactant based vesicles (niosomes) in drug delivery. Int. J. Pharm. 1998, 172:33-70.
7. Hurler J., Berg O.A., Skar M., Conradi A.H., Johnsen P.J., Škalko-Basnet N. Improved burns therapy: liposomes-in-hydrogel delivery system for mupirocin. J. Pharm. Sci. 2012, 101:3906-3915.
8. Dai T., Tanaka M., Huang Y.-Y., Hamblin M.R. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert. Rev. Anti. Infect. Ther. 2011, 9:857-879.
9. Bhattarai N., Gunn J., Zhang M. Chitosan-based hydrogels for controlled, localized drug delivery. Adv. Drug Deliv. Rev. 2010, 62:83-99.
10. Dharashivkar S.S., Sahasrabuddhe S.H., Saoji A.N. Niosomally encapsulated silver sulfadiazine gel for burn treatment. J. Microencapsul. 2014, 32:1-6.
11. Keating G.M., Scott L.J. Moxifloxacin: a review of its use in the management of bacterial infections. Drugs 2004, 64:2347-2377.
12. Jacobsen F., Fisahn C., Sorkin M., Thiele I., Hirsch T., Stricker I., Klaassen T., Roemer A., Fugmann B., Steinstraesser L. Efficacy of topically delivered moxifloxacin against wound infection by Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 2011, 55:2325-2334.
13. Arzani G., Haeri A., Daeihamed M., Bakhtiari-Kaboutaraki H., Dadashzadeh S. Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge. Int. J. Nanomedicine. 2015, 10:4797-4813.
14. Peer D., Margalit R. Physicochemical evaluation of a stability-driven approach to drug entrapment in regular and in surface-modified liposomes. Arch. Biochem. Biophys. 2000, 383:185-1190.
15. Tasdighi E., Azar Z.J., Mortazavi S.A. Development and in-vitro evaluation of a contraceptive vagino-adhesive propranolol hydrochloride gel. Iran. J. Pharm. Res. 2012, 11:13-26.
16. Contri R.V., Katzer T., Pohlmann A.R., Guterres S.S. Chitosan hydrogel containing capsaicinoids-loaded nanocapsules: an innovative formulation for topical delivery. Soft Matter 2010, 8:370-385.
17. Park S., Jeong U., Lee J., Park J. Preparation and characterization of bovine serum albumin-loaded cationic liposomes: effect of hydration phase. J. Pharm. Invest. 2010, 40:353-356.
18. Park S.-J., Choi S.G., Davaa E., Park J.-S. Encapsulation enhancement and stabilization of insulin in cationic liposomes. Int. J. Pharm. 2011, 415:267-272.
19. Crowe J.H., Tsvetkova N.M., Oliver A.E., Leidy C., Ricker J., Crowe L.M. Stabilization of liposomes by freeze-drying: lessons from nature. Liposome Technol.: Liposome Prep. Relat Tech. 2006, 261.
20. van Winden E.C. Freeze-drying of liposomes: theory and practice. Methods Enzymol. 2003, 367:99-110.
21. Shahiwala A., Misra A. Studies in topical application of niosomally entrapped nimesulide. J. Pharm. Pharm. Sci. 2002, 5:220-225.
22. Jin Y., Wen J., Garg S., Liu D., Zhou Y., Teng L., Zhang W. Development of a novel niosomal system for oral delivery of Ginkgo biloba extract. Int. J. Nanomed. 2013, 8:421-430.
23. Ragelle H., Crauste-Manciet S., Seguin J., Brossard D., Scherman D., Arnaud P., Chabot G.G. Nanoemulsion formulation of fisetin improves bioavailability and antitumour activity in mice. Int. J. Pharm. 2012, 427:452-459.
24. Waddad A.Y., Abbad S., Yu F., Munyendo W.L., Wang J., Lv H., Zhou J. Formulation, characterization and pharmacokinetics of Morin hydrate niosomes prepared from various non-ionic surfactants. Int. J. Pharm. 2013, 456:446-458.
25. Parthasarathi G., Udupa N., Umadevi P., Pillai G. Niosome encapsulated of vincristine sulfate: improved anticancer activity with reduced toxicity in mice. J. Drug Target. 1994, 2:173-182.
26. Kirby C., Clarke J., Gregoriadis G. Effect of the cholesterol content of small unilamellar liposomes on their stability in vivo and in vitro. Biochem. J. 1980, 186:591-598.
27. Ogihara-Umeda I., Kojima S. Cholesterol enhances the delivery of liposome-encapsulated gallium-67 to tumors. Eur. J. Nucl. Med. 1989, 15:612-617.
28. Akhter S., Kushwaha S., Warsi M.H., Anwar M., Ahmad M.Z., Ahmad I., Talegaonkar S., Khan Z.I., Khar R.K., Ahmad F.J. Development and evaluation of nanosized niosomal dispersion for oral delivery of Ganciclovir. Drug Dev. Ind. Pharm. 2012, 38:84-92.
29. Haeri A., Alinaghian B., Daeihamed M., Dadashzadeh S. Preparation and characterization of stable nanoliposomal formulation of fluoxetine as a potential adjuvant therapy for drug-resistant tumors. Iran. J. Pharm. Res. 2014, 13:3-14.
30. Kannan V., Balabathula P., Divi M.K., Thoma L.A., Wood G.C. Optimization of drug loading to improve physical stability of paclitaxel-loaded long-circulating liposomes. J. Liposome Res. 2014, 1-8.
31. Haeri A., Sadeghian S., Rabbani S., Anvari M.S., Boroumand M.A., Dadashzadeh S. Use of remote film loading methodology to entrap sirolimus into liposomes: preparation, characterization and in vivo efficacy for treatment of restenosis. Int. J. Pharm. 2011, 414:16-27.
32. Xu X., Costa A.P., Khan M.A., Burgess D.J. Application of quality by design to formulation and processing of protein liposomes. Int. J. Pharm. 2012, 434:349-359.
33. Haeri A., Sadeghian S., Rabbani S., Anvari M.S., Erfan M., Dadashzadeh S. PEGylated estradiol benzoate liposomes as a potential local vascular delivery system for treatment of restenosis. J. Microencapsul. 2012, 29:83-94.
34. Bajelan E., Haeri A., Vali A.M., Ostad S.N., Dadashzadeh S. Co-delivery of doxorubicin and PSC 833 (Valspodar) by stealth nanoliposomes for efficient overcoming of multidrug resistance. J. Pharm. Pharm. Sci. 2012, 15:568-582.
35. Zucker D., Marcus D., Barenholz Y., Goldblum A. Liposome drugs' loading efficiency: a working model based on loading conditions and drug's physicochemical properties. J. Control. Release 2009, 139:73-80.
36. Al Omari M., Jaafari D.S., Al-Sou'od K.A., Badwan A.A. Moxifloxacin hydrochloride. Profiles Drug Subst. Excipients Relat. Methodol. 2014, 39:299.
37. Peer D., Margalit R. Loading mitomycin C inside long circulating hyaluronan targeted nano-liposomes increases its antitumor activity in three mice tumor models. Int. J. Cancer. 2004, 108:780-789.
38. Elron-Gross I., Glucksam Y., Margalit R. Liposomal dexamethasone-diclofenac combinations for local osteoarthritis treatment. Int. J. Pharm. 2009, 376:84-91.
39. Haeri A., Sadeghian S., Rabbani S., Anvari M.S., Lavasanifar A., Amini M., Dadashzadeh S. Sirolimus-loaded stealth colloidal systems attenuate neointimal hyperplasia after balloon injury: a comparison of phospholipid micelles and liposomes. Int. J. Pharm. 2013, 455:320-330.
40. Wasserman V., Kizelsztein P., Garbuzenko O., Kohen R., Ovadia H., Tabakman R., Barenholz Y. The antioxidant tempamine: in vitro antitumor and neuroprotective effects and optimization of liposomal encapsulation and release. Langmuir 2007, 23:1937-1947.
41. Gubernator J., Chwastek G., Korycińska M., Stasiuk M., Grynkiewicz G., Lewrick F., Süss R., Kozubek A. The encapsulation of idarubicin within liposomes using the novel EDTA ion gradient method ensures improved drug retention in vitro and in vivo. J. Control. Release 2010, 146:68-75.
42. Hossann M., Wang T., Wiggenhorn M., Schmidt R., Zengerle A., Winter G., Eibl H., Peller M., Reiser M., Issels R.D. Size of thermosensitive liposomes influences content release. J. Control. Release 2010, 147:436-443.
43. Hurler J., Žakelj S., Mravljak J., Pajk S., Kristl A., Schubert R., Škalko-Basnet N. The effect of lipid composition and liposome size on the release properties of liposomes-in-hydrogel. Int. J. Pharm. 2013, 456:49-57.
44. Ritger P.L., Peppas N.A. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs spheres, cylinders or discs. J. Control. Release 1987, 5:23-36.
45. Lippacher A., Müller R., Mäder K. Semisolid SLN™ dispersions for topical application: influence of formulation and production parameters on viscoelastic properties. Eur. J. Pharm. Biopharm. 2002, 53:155-160.
46. Varshosaz J., Jaffari F., Karimzadeh S. Development of bioadhesive chitosan gels for topical delivery of lidocaine. Sci. Pharm. 2006, 74:209-232.
47. Vermani K., Garg S., Zaneveld L.J. Assemblies for in vitro measurement of bioadhesive strength and retention characteristics in simulated vaginal environment. Drug Dev. Ind. Pharm. 2002, 28:1133-1146.
48. Kaur P., Garg T., Vaidya B., Prakash A., Rath G., Goyal A.K. Brain delivery of intranasal in situ gel of nanoparticulated polymeric carriers containing antidepressant drug: behavioral and biochemical assessment. J. Drug Target. 2015, 23:275-286.
49. Soussy C.J., Nguyen J., Goldstein F., Dabernat H., Andremont A., Leclercq R., Drugeon H., Cavallo P., Chardon H., Etienne J. In vitro antibacterial activity of moxifloxacin against hospital isolates: a multicentre study. Clin. Microbiol. Infect. 2003, 9:997-1005.
50. Omri A., Ravaoarinoro M. Comparison of the bactericidal action of amikacin, netilmicin and tobramycin in free and liposomal formulation against Pseudomonas aeruginosa. Chemotherapy 1996, 42:170-176.
51. Amusa A.S., Satish J., Gopalakrishna P. In vitro activities of fluoroquinolones entrapped in non-ionic surfactant vesicles against ciprofloxacin-resistant bacteria strains. J. Pharm. Technol. Drug Res. 2012, 1:5.
52. Huang C.-M., Chen C.-H., Pornpattananangkul D., Zhang L., Chan M., Hsieh M.-F., Zhang L. Eradication of drug resistant Staphylococcus aureus by liposomal oleic acids. Biomaterials 2011, 32:214-221.
53. Mugabe C., Azghani A.O., Omri A. Liposome-mediated gentamicin delivery: development and activity against resistant strains of Pseudomonas aeruginosa isolated from cystic fibrosis patients. J. Antimicrob. Chemother. 2005, 55:269-271.
54. Kong M., Chen X.G., Xing K., Park H.J. Antimicrobial properties of chitosan and mode of action: a state of the art review. Int. J. Food Microbiol. 2010, 144:51-63.
55. Chung Y.-C., Su Y.-P., Chen C.-C., Jia G., Wang H.-l., Wu J.G., Lin J.-G. Relationship between antibacterial activity of chitosan and surface characteristics of cell wall. Acta Pharmacol. Sin. 2004, 25:932-936.
56. No H.K., Park N.Y., Lee S.H., Meyers S.P. Antibacterial activity of chitosans and chitosan oligomers with different molecular weights. Int. J. Food Microbiol. 2002, 74:65-72.
57. Ding F., Nie Z., Deng H., Xiao L., Du Y., Shi X. Antibacterial hydrogel coating by electrophoretic co-deposition of chitosan/alkynyl chitosan. Carbohydr. Polym. 2013, 98:1547-1552.
58. Wang X., Du Y., Liu H. Preparation, characterization and antimicrobial activity of chitosan-Zn complex. Carbohydr. Polym. 2004, 56:21-26.