Improved burns therapy: Liposomes-in-hydrogel delivery system for mupirocin

Journal of Pharmaceutical Sciences

Volumn 101, Issue 10, 2012, Pages 3906-3915

  Hurler, Julia ^a   Berg, Ole Aleksander ^a   Skar, Merete ^a   Conradi, Anne Hilde ^a   Johnsen, Pål Jarle ^a   Škalko Basnet, Nataša ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Anti infectives; Chitosan; Drug delivery system; Hydrogels; Liposomes; Skin

Indexed keywords

CHITOSAN; LIPOSOME; PHOSPHATIDYLCHOLINE; PSEUDOMONIC ACID;

ADHESION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACILLUS SUBTILIS; BURN; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENCAPSULATION; ENTEROCOCCUS FAECALIS; EX VIVO STUDY; HYDROGEL; IN VITRO STUDY; MICROCOCCUS LUTEUS; NONHUMAN; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 84865390892     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23260     Document Type: Article

References (36)

1. Peck MD. 2011. Epidemiology of burns throughout the world. Part I: Distribution and risk factors. Burns 37:1087-1110.
2. Elsner JJ, Egozi D, Ullmann Y, Berdicevsky I, Shefy-Peleg A, Zilberman M. 2011. Novel biodegradable composite wound dressings with controlled release of antibiotics: Results in a guinea pig burn model. Burns 37:896-904.
3. Murphy KD, Lee JO, Herndon DN. 2003. Current pharmacotherapy for the treatment of severe burns. Expert Opin Pharmacother 4:369-381.
4. Elsner JJ, Shefy-Peleg A, Zilberman M. 2010. Novel biodegradable composite wound dressing with controlled release of antibiotics: Microstructure, mechanical and physical properties. J Biomed Mater Res B Appl Biomater 93B:425-435.
5. Guggenheim M, Thurnheer T, Gmür R, Giovanoli P, Guggenheim B. 2011. Validation of the Zürich burn-biofilm model. Burns 37:1125-1133.
6. Gisby J, Bryant J. 2000. Efficacy of a new cream formulation of mupirocin: Comparison with oral and topical agents in experimental skin infections. Antimicrob Agents Chemother 44:255-260.
7. Pavelic Z, Skalko-Basnet N, Schubert R. 2001. Liposomal gels for vaginal delivery. Int J Pharm 219:139-149.
8. Hurler J, Skalko-Basnet N. 2012. Potentials of chitosan-based delivery systems in wound therapy: Bioadhesion study. J Funct Biomater 3:37-48.
9. Alsarra IA. 2009. Chitosan topical gel formulation in the management of burn wounds. Int J Biol Macromol 45:16-21.
10. Ribeiro MP, Espiga A, Silva D, Baptista P, Henriques J, Ferreira C, Silva JC, Borges JP, Pires E, Chaves P, Correia IJ. 2009. Development of a new chitosan hydrogel for wound dressing. Wound Repair Regen 17:817-824.
11. Echevarría L, Blanco-Príeto MJ, Campanero MA, Santoyo S, Ygartua P. 2003. Development and validation of a liquid chromatographic method for in vitro mupirocin quantification in both skin layers and percutaneous penetration studies. J Chromatogr B 796:233-241.
12. Hurler J, Engesland A, Poorahmary Kermany B, Skalko-Basnet N. 2011. Improved texture analysis for hydrogel characterization: Gel cohesiveness, adhesiveness and hardness. J Appl Polym Sci 125:180-188.
13. Ji JA, Liu J, Shire SJ, Kamerzell TJ, Hong S, Billeci K, Shen Y, Wang YJ. 2010. Characteristics of rhVEGF release from topical hydrogel formulations. Pharm Res 27:644-654.
14. Basnet P, Hussain H, Tho I, Skalko-Basnet N. 2012. Liposomal delivery system enhances anti-inflammatory properties of curcumin. J Pharm Sci 101:598-609.
15. du Plessis J, Ramachandran C, Weiner N, Müller DG. 1994. The influence of particle size of liposomes on the deposition of drug into skin. Int J Pharm 103:277-282.
16. Škalko N, Čajkovac M, Jalšenjak I. 1998. Liposomes with metronidazole for topical use: The choice of preparation method and vehicle. J Lipos Res 8:283-293.
17. Sutherland R, Boon RJ, Griffin KE, Masters PJ, Slocombe B, White AR. 1985. Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Antimicrob Agents Chemother 27:495-498.
18. Simpson IN, Gisby J, Hemingway CP, Durodie J, Macpherson I. 1995. Evaluation of mupirocin E-test for determination of isolate susceptibility: Comparison with standard agar dilution techniques. J Clin Microbiol 33:2254-2259.
19. Jones DS, Woolfson AD, Brown AF, Coulter WA, McClelland C, Irwin CR. 2000. Design, characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodonatal disease. J Control Release 67:357-368.
20. Keegan G, Smart J, Ingram M, Barnes L, Rees G, Burnett G. 2007. An in vitro assessment of bioadhesive zinc/carbomer complexes for antimicrobial therapy within the oral cavity. Int J Pharm 340:92-96.
21. Khutoryanskiy VV. 2011. Advances in mucoadhesion and mucoadhesive polymers. Macromol Biosci 11:748-764.
22. Cevc G. 2004. Lipid vesicles and other colloids as drug carriers on the skin. Adv Drug Deliv Rev 56:675-711.
23. Knudsen NØ, Jorgensen L, Hansen J, Vermehren C, Frokjaer S, Foged C. 2011. Targeting of liposome-associated calcipotriol to the skin: Effect of liposomal membrane fluidity and skin barrier integrity. Int J Pharm 416:478-485.
24. Gattu S, Maibach HI. 2010. Enhanced absorption through damaged skin: An overview of the in vitro human model. Skin Pharmacol Physiol 23:171-176.
25. Moddaresi M, Brown MB, Zhao Y, Tamburic S, Jones SA. 2010. The role of vehicle-nanoparticle interactions in topical drug delivery. Int J Pharm 400:176-182.
26. Ye F, Yaghmur A, Jensen H, Larsen SW, Larsen C, Østergaard J. 2011. Real-time UV imaging of drug diffusion and release from Pluronic F127 hydrogels. Eur J Pharm Sci 43:236-243.
27. Brandl F, Kastner F, Gschwind RM, Blunk T, Teβmar J, Göpferich A. 2010. Hydrogel-based drug delivery systems: Comparison of drug diffusivity and release kinetics. J Control Release 142:221-228.
28. Homann H-H, Rosbach O, Moll W, Vogt PM, Germann G, Hopp M, Langer-Brauburger B, Reimer K, Steinau H-U. 2007. A liposome hydrogel with polyvinyl-pyrrolidone iodine in the local treatment of partial-thickness burn wounds. Ann Plast Surg 59:423-427.
29. Kang J-W, Davaa E, Kim Y-T, Park J-S. 2010. A new vaginal delivery system of amphotericin B: A dispersion of cationic liposomes in a thermosensitive gel. J Drug Target 18:637-644.
30. Mulik R, Kulkarni V, Muthy RSR. 2009. Chitosan-based thermosensitive hydrogel containing liposomes for sustained delivery of cytarabine. Drug Dev Ind Pharm 35:49-56.
31. Paavola A, Kilpeläinen I, Yliruusi J, Rosenberg P. 2000. Controlled release injectable liposomal gel of ibuprofen for epidural analgesia. Int J Pharm 199:85-93.
32. Rubio L, Alonso C, López O, Rodríguez G, Coderch L, Notario J, de la Maza A, Parra JL. 2011. Barrier function of intact and impaired skin: Percutaneous penetration of caffeine and salicylic acid. Int J Dermatol 50:881-889.
33. Jacobi U, Kaiser M, Toll R, Mangelsdorf S, Audring H, Otberg N, Sterry W, Lademann J. 2007. Porcine ear skin: An in vitro model for human skin. Skin Res Technol 13:19-24.
34. Barbero AM, Frasch HF. 2009. Pig and guinea pig skin as surrogates for human in vitro penetration studies: A quantitative review. Toxicol In Vitro 23:1-13.
35. No HK, Park NY, Lee SH, Meyers SP. 2002. Antibacterial activity of chitosans and chitosan oligomers with different molecular weights. Int J Food Microb 74:65-72.
36. Deǧim Z, Çelebi N, Alemdaroǧlu C, Deevci M, Òztùrk S, Òzoǧul C. 2011. Evaluation of chitosan gel containing liposome-loaded epidermal growth factor on burn wound healing. Int Wound J 8:343-354.