Adapting Koch's postulates: Criteria for disease causation must take microbial interactions into account

Science

Volumn 351, Issue 6270, 2016, Pages 224-226

  Byrd, Allyson L ^a,b   Segre, Julia A ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; BACTERIUM; COLONIZATION; ECOLOGICAL THEORY; INFECTIOUS DISEASE; MICROBIAL ACTIVITY; PATHOGEN; RESEARCH WORK;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; DISEASE PREDISPOSITION; GENETIC VARIABILITY; HEALTH STATUS; INFECTION; MEDICAL HISTORY; MICROBIAL COLONIZATION; MICROBIAL COMMUNITY; NONHUMAN; ORGANISMAL INTERACTION; PATHOGENESIS; PRACTICE GUIDELINE; PRIORITY JOURNAL; ANIMAL; CHEMICALLY INDUCED; COMMUNICABLE DISEASE; CROSS INFECTION; DIARRHEA; DRUG EFFECTS; HOST PATHOGEN INTERACTION; HUMAN; MICROBIAL CONSORTIUM; MICROBIOLOGY; MOUSE; PATHOGENICITY; PEPTOCLOSTRIDIUM DIFFICILE; PSEUDOMEMBRANOUS COLITIS; SYMBIOSIS;

ANTIINFECTIVE AGENT;

ANIMALS; ANTI-BACTERIAL AGENTS; CLOSTRIDIUM DIFFICILE; COMMUNICABLE DISEASES; CROSS INFECTION; DIARRHEA; DISEASE SUSCEPTIBILITY; ENTEROCOLITIS, PSEUDOMEMBRANOUS; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE; MICROBIAL CONSORTIA; SYMBIOSIS;

EID: 84954530483     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aad6753     Document Type: Article

References (14)

1. R. Koch, in Xth International Congress of Medicine, Berlin (1890).
2. A. S. Evans, Yale J. Biol. Med. 49, 175 (1976).
3. T. M. Rivers, J. Bacteriol. 33, 1 (1937).
4. S. Falkow, Rev. Infect. Dis. 10 (suppl. 2), S274 (1988).
5. D. N. Fredricks, D. A. Relman, Clin. Microbiol. Rev. 9, 18 (1996).
6. C. G. Buffie, E. G. Pamer, Nat. Rev. Immunol. 13, 790 (2013).
7. C. G. Buffie et al. Nature 517, 205 (2015).
8. A. M. Schieber et al. Science 350, 558 (2015).
9. J. A. Sorg, A. L. Sonenshein, J. Bacteriol. 192, 4983 (2010).
10. A. Nissle, Med. Welt 29-30, 1519 (1961).
11. M. Sassone-Corsi, M. Raffatellu, J. Immunol. 194, 4081 (2015).
12. T. D. Lawley et al., PLOS Pathogens 8, e1002995 (2012).
13. E. van Nood et al., N. Engl. J. Med. 368, 407 (2013).
14. T. J. Break et al. Infect. Immun. 83, 958 (2015).